In recent years, studies suggest that the mammalian genome undergoes various epigenetic modifications during development and embryonic stem cell (ESC) differentiation. Understanding the mechanisms that control these epigenetic signals is essential in deciphering stem cell biology and the patterns of gene expression during cellular differentiation. ESC gene expression relies heavily on transcriptional factor networks and epigenetic signals that give stem cells their ability to differentiate into different cell types -- histone modification, histone variants, and DNA methylation. Diagenode provides a full solution for your every epigenetics and stem cell research need including ChIP and ChIP-seq antibodies and kits for low cell amounts, DNA methylation kits and antibodies, and sample processing instruments.
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