The Diagenode HighCell# ChIP kit protein A contains protein A-coated paramagnetic beads (and negative IgG from rabbit) to allow you to work with rabbit polyclonal antibodies. The HighCell# ChIP kit protein G contains protein G-coated paramagnetic beads (and negative IgG from mouse) to allow you to work with mouse monoclonal antibodies. As positive control or target antibody, choose one of our ChIP-grade antibodies against main histone modifications or your protein of interest.