Notice (8): Undefined variable: solution_of_interest [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'product' => array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
)
)
$language = 'jp'
$meta_keywords = 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody'
$meta_description = 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.'
$meta_title = 'SMAD3 polyclonal antibody - Classic | Diagenode'
$product = array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '19',
'position' => '10',
'parent_id' => '40',
'name' => 'WB',
'description' => '<p><strong>Western blot</strong> : The quality of antibodies used in this technique is crucial for correct and specific protein identification. Diagenode offers huge selection of highly sensitive and specific western blot-validated antibodies.</p>
<p>Learn more about: <a href="https://www.diagenode.com/applications/western-blot">Loading control, MW marker visualization</a><em>. <br /></em></p>
<p><em></em>Check our selection of antibodies validated in Western blot.</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'western-blot-antibodies',
'meta_keywords' => ' Western Blot Antibodies ,western blot protocol,Western Blotting Products,Polyclonal antibodies ,monoclonal antibodies ',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for western blot applications',
'meta_title' => ' Western Blot - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-04-26 12:44:51',
'created' => '2015-01-07 09:20:00',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '30',
'position' => '50',
'parent_id' => '4',
'name' => 'Transcription',
'description' => '<p><span style="font-weight: 400;">The list of Diagenode’s highly specific antibodies for transcription studies includes the antibodies against many transcription factors and nuclear receptors. Check the list below to see our targets.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li><span style="font-weight: 400;"> Highly sensitive and specific</span></li>
<li><span style="font-weight: 400;"> Cost-effective (requires less antibody per reaction)</span></li>
<li><span style="font-weight: 400;"> Batch-specific data is available on the website</span></li>
<li><span style="font-weight: 400;"> Expert technical support</span></li>
<li><span style="font-weight: 400;"> Sample sizes available</span></li>
<li><span style="font-weight: 400;"> 100% satisfaction guarantee</span></li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'transcription-factor',
'cookies_tag_id' => null,
'meta_keywords' => ' Transcription factor antibodies,monoclonal antibodies,polyclonal antibodies',
'meta_description' => 'Diagenode offers polyclonal and monoclonal antibodies for Transcription studie',
'meta_title' => 'Transcription factor Antibodies | Diagenode',
'modified' => '2020-07-06 12:59:19',
'created' => '2015-03-12 10:20:08',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '909',
'name' => 'SMAD3 polyclonal antibody C15410328',
'description' => '<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet_SMAD3_polyclonal_antibody_C15410328.pdf',
'slug' => 'datasheet-smad3-polyclonal-antibody-c15410328',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-22 14:30:53',
'created' => '2016-06-22 14:30:53',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '38',
'name' => 'Epigenetic Antibodies Brochure',
'description' => '<p>More than in any other immuoprecipitation assays, quality antibodies are critical tools in many epigenetics experiments. Since 10 years, Diagenode has developed the most stringent quality production available on the market for antibodies exclusively focused on epigenetic uses. All our antibodies have been qualified to work in epigenetic applications.</p>',
'image_id' => null,
'type' => 'Brochure',
'url' => 'files/brochures/Epigenetic_Antibodies_Brochure.pdf',
'slug' => 'epigenetic-antibodies-brochure',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-15 11:24:06',
'created' => '2015-07-03 16:05:27',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '250',
'name' => 'product/antibodies/antibody.png',
'alt' => 'Mouse IgG',
'modified' => '2020-11-27 07:00:09',
'created' => '2015-07-17 10:12:18',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '2230',
'name' => 'SMAD3 Antibody SDS GB en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-GB-en-GHS_1_0.pdf',
'countries' => 'GB',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '2232',
'name' => 'SMAD3 Antibody SDS US en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-US-en-GHS_1_0.pdf',
'countries' => 'US',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '2227',
'name' => 'SMAD3 Antibody SDS DE de',
'language' => 'de',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-DE-de-GHS_1_0.pdf',
'countries' => 'DE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '2231',
'name' => 'SMAD3 Antibody SDS JP ja',
'language' => 'ja',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-JP-ja-GHS_1_0.pdf',
'countries' => 'JP',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '2226',
'name' => 'SMAD3 Antibody SDS BE nl',
'language' => 'nl',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-nl-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '2225',
'name' => 'SMAD3 Antibody SDS BE fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-fr-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '2229',
'name' => 'SMAD3 Antibody SDS FR fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-FR-fr-GHS_1_0.pdf',
'countries' => 'FR',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = false
$other_formats = array()
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
'id' => '4443',
'product_id' => '2820',
'application_id' => '32'
)
)
$slugs = array(
(int) 0 => 'immunohistochemistry'
)
$applications = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'locale' => 'jpn'
)
$description = '<p>Immunohistochemistry</p>'
$name = 'IHC'
$document = array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
'id' => '2132',
'product_id' => '2820',
'document_id' => '11'
)
)
$sds = array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
'id' => '3883',
'product_id' => '2820',
'safety_sheet_id' => '2228'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: header [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'product' => array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
)
)
$language = 'jp'
$meta_keywords = 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody'
$meta_description = 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.'
$meta_title = 'SMAD3 polyclonal antibody - Classic | Diagenode'
$product = array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '19',
'position' => '10',
'parent_id' => '40',
'name' => 'WB',
'description' => '<p><strong>Western blot</strong> : The quality of antibodies used in this technique is crucial for correct and specific protein identification. Diagenode offers huge selection of highly sensitive and specific western blot-validated antibodies.</p>
<p>Learn more about: <a href="https://www.diagenode.com/applications/western-blot">Loading control, MW marker visualization</a><em>. <br /></em></p>
<p><em></em>Check our selection of antibodies validated in Western blot.</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'western-blot-antibodies',
'meta_keywords' => ' Western Blot Antibodies ,western blot protocol,Western Blotting Products,Polyclonal antibodies ,monoclonal antibodies ',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for western blot applications',
'meta_title' => ' Western Blot - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-04-26 12:44:51',
'created' => '2015-01-07 09:20:00',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '30',
'position' => '50',
'parent_id' => '4',
'name' => 'Transcription',
'description' => '<p><span style="font-weight: 400;">The list of Diagenode’s highly specific antibodies for transcription studies includes the antibodies against many transcription factors and nuclear receptors. Check the list below to see our targets.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li><span style="font-weight: 400;"> Highly sensitive and specific</span></li>
<li><span style="font-weight: 400;"> Cost-effective (requires less antibody per reaction)</span></li>
<li><span style="font-weight: 400;"> Batch-specific data is available on the website</span></li>
<li><span style="font-weight: 400;"> Expert technical support</span></li>
<li><span style="font-weight: 400;"> Sample sizes available</span></li>
<li><span style="font-weight: 400;"> 100% satisfaction guarantee</span></li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'transcription-factor',
'cookies_tag_id' => null,
'meta_keywords' => ' Transcription factor antibodies,monoclonal antibodies,polyclonal antibodies',
'meta_description' => 'Diagenode offers polyclonal and monoclonal antibodies for Transcription studie',
'meta_title' => 'Transcription factor Antibodies | Diagenode',
'modified' => '2020-07-06 12:59:19',
'created' => '2015-03-12 10:20:08',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '909',
'name' => 'SMAD3 polyclonal antibody C15410328',
'description' => '<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet_SMAD3_polyclonal_antibody_C15410328.pdf',
'slug' => 'datasheet-smad3-polyclonal-antibody-c15410328',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-22 14:30:53',
'created' => '2016-06-22 14:30:53',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '38',
'name' => 'Epigenetic Antibodies Brochure',
'description' => '<p>More than in any other immuoprecipitation assays, quality antibodies are critical tools in many epigenetics experiments. Since 10 years, Diagenode has developed the most stringent quality production available on the market for antibodies exclusively focused on epigenetic uses. All our antibodies have been qualified to work in epigenetic applications.</p>',
'image_id' => null,
'type' => 'Brochure',
'url' => 'files/brochures/Epigenetic_Antibodies_Brochure.pdf',
'slug' => 'epigenetic-antibodies-brochure',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-15 11:24:06',
'created' => '2015-07-03 16:05:27',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '250',
'name' => 'product/antibodies/antibody.png',
'alt' => 'Mouse IgG',
'modified' => '2020-11-27 07:00:09',
'created' => '2015-07-17 10:12:18',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '2230',
'name' => 'SMAD3 Antibody SDS GB en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-GB-en-GHS_1_0.pdf',
'countries' => 'GB',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '2232',
'name' => 'SMAD3 Antibody SDS US en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-US-en-GHS_1_0.pdf',
'countries' => 'US',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '2227',
'name' => 'SMAD3 Antibody SDS DE de',
'language' => 'de',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-DE-de-GHS_1_0.pdf',
'countries' => 'DE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '2231',
'name' => 'SMAD3 Antibody SDS JP ja',
'language' => 'ja',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-JP-ja-GHS_1_0.pdf',
'countries' => 'JP',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '2226',
'name' => 'SMAD3 Antibody SDS BE nl',
'language' => 'nl',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-nl-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '2225',
'name' => 'SMAD3 Antibody SDS BE fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-fr-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '2229',
'name' => 'SMAD3 Antibody SDS FR fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-FR-fr-GHS_1_0.pdf',
'countries' => 'FR',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = false
$other_formats = array()
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
'id' => '4443',
'product_id' => '2820',
'application_id' => '32'
)
)
$slugs = array(
(int) 0 => 'immunohistochemistry'
)
$applications = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'locale' => 'jpn'
)
$description = '<p>Immunohistochemistry</p>'
$name = 'IHC'
$document = array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
'id' => '2132',
'product_id' => '2820',
'document_id' => '11'
)
)
$sds = array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
'id' => '3883',
'product_id' => '2820',
'safety_sheet_id' => '2228'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: message [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'product' => array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
)
)
$language = 'jp'
$meta_keywords = 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody'
$meta_description = 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.'
$meta_title = 'SMAD3 polyclonal antibody - Classic | Diagenode'
$product = array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '19',
'position' => '10',
'parent_id' => '40',
'name' => 'WB',
'description' => '<p><strong>Western blot</strong> : The quality of antibodies used in this technique is crucial for correct and specific protein identification. Diagenode offers huge selection of highly sensitive and specific western blot-validated antibodies.</p>
<p>Learn more about: <a href="https://www.diagenode.com/applications/western-blot">Loading control, MW marker visualization</a><em>. <br /></em></p>
<p><em></em>Check our selection of antibodies validated in Western blot.</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'western-blot-antibodies',
'meta_keywords' => ' Western Blot Antibodies ,western blot protocol,Western Blotting Products,Polyclonal antibodies ,monoclonal antibodies ',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for western blot applications',
'meta_title' => ' Western Blot - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-04-26 12:44:51',
'created' => '2015-01-07 09:20:00',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '30',
'position' => '50',
'parent_id' => '4',
'name' => 'Transcription',
'description' => '<p><span style="font-weight: 400;">The list of Diagenode’s highly specific antibodies for transcription studies includes the antibodies against many transcription factors and nuclear receptors. Check the list below to see our targets.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li><span style="font-weight: 400;"> Highly sensitive and specific</span></li>
<li><span style="font-weight: 400;"> Cost-effective (requires less antibody per reaction)</span></li>
<li><span style="font-weight: 400;"> Batch-specific data is available on the website</span></li>
<li><span style="font-weight: 400;"> Expert technical support</span></li>
<li><span style="font-weight: 400;"> Sample sizes available</span></li>
<li><span style="font-weight: 400;"> 100% satisfaction guarantee</span></li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'transcription-factor',
'cookies_tag_id' => null,
'meta_keywords' => ' Transcription factor antibodies,monoclonal antibodies,polyclonal antibodies',
'meta_description' => 'Diagenode offers polyclonal and monoclonal antibodies for Transcription studie',
'meta_title' => 'Transcription factor Antibodies | Diagenode',
'modified' => '2020-07-06 12:59:19',
'created' => '2015-03-12 10:20:08',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '909',
'name' => 'SMAD3 polyclonal antibody C15410328',
'description' => '<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet_SMAD3_polyclonal_antibody_C15410328.pdf',
'slug' => 'datasheet-smad3-polyclonal-antibody-c15410328',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-22 14:30:53',
'created' => '2016-06-22 14:30:53',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '38',
'name' => 'Epigenetic Antibodies Brochure',
'description' => '<p>More than in any other immuoprecipitation assays, quality antibodies are critical tools in many epigenetics experiments. Since 10 years, Diagenode has developed the most stringent quality production available on the market for antibodies exclusively focused on epigenetic uses. All our antibodies have been qualified to work in epigenetic applications.</p>',
'image_id' => null,
'type' => 'Brochure',
'url' => 'files/brochures/Epigenetic_Antibodies_Brochure.pdf',
'slug' => 'epigenetic-antibodies-brochure',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-15 11:24:06',
'created' => '2015-07-03 16:05:27',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '250',
'name' => 'product/antibodies/antibody.png',
'alt' => 'Mouse IgG',
'modified' => '2020-11-27 07:00:09',
'created' => '2015-07-17 10:12:18',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '2230',
'name' => 'SMAD3 Antibody SDS GB en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-GB-en-GHS_1_0.pdf',
'countries' => 'GB',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '2232',
'name' => 'SMAD3 Antibody SDS US en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-US-en-GHS_1_0.pdf',
'countries' => 'US',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '2227',
'name' => 'SMAD3 Antibody SDS DE de',
'language' => 'de',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-DE-de-GHS_1_0.pdf',
'countries' => 'DE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '2231',
'name' => 'SMAD3 Antibody SDS JP ja',
'language' => 'ja',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-JP-ja-GHS_1_0.pdf',
'countries' => 'JP',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '2226',
'name' => 'SMAD3 Antibody SDS BE nl',
'language' => 'nl',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-nl-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '2225',
'name' => 'SMAD3 Antibody SDS BE fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-fr-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '2229',
'name' => 'SMAD3 Antibody SDS FR fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-FR-fr-GHS_1_0.pdf',
'countries' => 'FR',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = false
$other_formats = array()
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
'id' => '4443',
'product_id' => '2820',
'application_id' => '32'
)
)
$slugs = array(
(int) 0 => 'immunohistochemistry'
)
$applications = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'locale' => 'jpn'
)
$description = '<p>Immunohistochemistry</p>'
$name = 'IHC'
$document = array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
'id' => '2132',
'product_id' => '2820',
'document_id' => '11'
)
)
$sds = array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
'id' => '3883',
'product_id' => '2820',
'safety_sheet_id' => '2228'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: campaign_id [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'product' => array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
)
)
$language = 'jp'
$meta_keywords = 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody'
$meta_description = 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.'
$meta_title = 'SMAD3 polyclonal antibody - Classic | Diagenode'
$product = array(
'Product' => array(
'id' => '2820',
'antibody_id' => '483',
'name' => 'SMAD3 polyclonal antibody ',
'description' => '<p>Alternative names: <strong>MADH3</strong>, <strong>JV15-2</strong>, <strong>HMAD-3</strong>, <strong>HSMAD3</strong>, <strong>MAD3</strong>, <strong>LDS3</strong>, <strong>HSPC193</strong>, <strong>SMAD 3</strong></p>
<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-5 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-wb.jpg" alt="WB" /></p>
</div>
<div class="small-7 columns">
<p><small> <strong>Figure 1. Western blot analysis using the Diagenode antibody directed against SMAD3</strong><br />Lysates from different cells treated with TGFb (+) or untreated control cells (-) were analysed by Western blot using the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:500. The position of SMAD3 is indicated on the right. The antibody recognizes both the phopsphorylated and the unphosphorykated SMAD3.</small></p>
</div>
</div>
<div class="row">
<div class="small-3 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/C15410228-ihc.jpg" alt="IHC" /></p>
</div>
<div class="small-9 columns">
<p><small> <strong>Figure 2. Immunohistochemistry using the Diagenode antibody directed against SMAD3</strong><br />Formalin fixed paraffin embedded cancerous human liver tissue was stained with the Diagenode antibody against SMAD3 (Cat. No. C15410328) diluted 1:400, followed by a peroxidise labelled anti-rabbit antibody. The presence of the SMAD3 protein is shown by the grey color; red indictaed the nuclei.</small></p>
</div>
</div>',
'label2' => 'Target description',
'info2' => '<p>SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.</p>',
'label3' => '',
'info3' => '',
'format' => '100 μg/ 86 μl',
'catalog_number' => 'C15410328',
'old_catalog_number' => '',
'sf_code' => 'C15410328-D001-000526',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '435',
'price_USD' => '440',
'price_GBP' => '395',
'price_JPY' => '68145',
'price_CNY' => '',
'price_AUD' => '1100',
'country' => 'ALL',
'except_countries' => 'None',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => '0000-00-00',
'slug' => 'smad3-polyclonal-antibody-100-ug',
'meta_title' => 'SMAD3 polyclonal antibody - Classic | Diagenode',
'meta_keywords' => 'Polyclonal antibody,synthetic peptide,C-terminal par of the protein,SMAD3 polyclonal antibody',
'meta_description' => 'Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.',
'modified' => '2022-01-05 16:03:52',
'created' => '2016-06-22 14:22:06',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '483',
'name' => 'SMAD3 polyclonal antibody',
'description' => 'SMAD3 (UniProt/Swiss-Prot entry P84022) belongs to the SMAD (‘mothers against decapentaplegic) family of proteins which are signal transducers and transcriptional modulators involved in multiple pathways. SMAD3 is activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases which phosphorylates the C-terminal serines 423 and 425. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and is involved in chondrogenesis, osteogenesis and wound healing. It is also thought to play a role in carcinogenesis.',
'clonality' => '',
'isotype' => '',
'lot' => '001',
'concentration' => '1.17 μg/μl',
'reactivity' => 'Human',
'type' => 'Polyclonal',
'purity' => 'Affinity purified',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>Western Blotting</td>
<td>1:500</td>
<td>Fig 1</td>
</tr>
<tr>
<td>Immunohistochemistry</td>
<td>1:400</td>
<td>Fig 2</td>
</tr>
</tbody>
</table>',
'storage_conditions' => '',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-08-03 16:42:43',
'created' => '2016-06-22 14:22:56',
'select_label' => '483 - SMAD3 polyclonal antibody (001 - 1.17 μg/μl - Human - Affinity purified - Rabbit)'
),
'Slave' => array(),
'Group' => array(),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '19',
'position' => '10',
'parent_id' => '40',
'name' => 'WB',
'description' => '<p><strong>Western blot</strong> : The quality of antibodies used in this technique is crucial for correct and specific protein identification. Diagenode offers huge selection of highly sensitive and specific western blot-validated antibodies.</p>
<p>Learn more about: <a href="https://www.diagenode.com/applications/western-blot">Loading control, MW marker visualization</a><em>. <br /></em></p>
<p><em></em>Check our selection of antibodies validated in Western blot.</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'western-blot-antibodies',
'meta_keywords' => ' Western Blot Antibodies ,western blot protocol,Western Blotting Products,Polyclonal antibodies ,monoclonal antibodies ',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for western blot applications',
'meta_title' => ' Western Blot - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-04-26 12:44:51',
'created' => '2015-01-07 09:20:00',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '30',
'position' => '50',
'parent_id' => '4',
'name' => 'Transcription',
'description' => '<p><span style="font-weight: 400;">The list of Diagenode’s highly specific antibodies for transcription studies includes the antibodies against many transcription factors and nuclear receptors. Check the list below to see our targets.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li><span style="font-weight: 400;"> Highly sensitive and specific</span></li>
<li><span style="font-weight: 400;"> Cost-effective (requires less antibody per reaction)</span></li>
<li><span style="font-weight: 400;"> Batch-specific data is available on the website</span></li>
<li><span style="font-weight: 400;"> Expert technical support</span></li>
<li><span style="font-weight: 400;"> Sample sizes available</span></li>
<li><span style="font-weight: 400;"> 100% satisfaction guarantee</span></li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'transcription-factor',
'cookies_tag_id' => null,
'meta_keywords' => ' Transcription factor antibodies,monoclonal antibodies,polyclonal antibodies',
'meta_description' => 'Diagenode offers polyclonal and monoclonal antibodies for Transcription studie',
'meta_title' => 'Transcription factor Antibodies | Diagenode',
'modified' => '2020-07-06 12:59:19',
'created' => '2015-03-12 10:20:08',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '909',
'name' => 'SMAD3 polyclonal antibody C15410328',
'description' => '<p>Polyclonal antibody raised in rabbit against SMAD3 (SMAD Family Member 3) using a KLH conjugated synthetic peptide from the C-terminal par of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet_SMAD3_polyclonal_antibody_C15410328.pdf',
'slug' => 'datasheet-smad3-polyclonal-antibody-c15410328',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-22 14:30:53',
'created' => '2016-06-22 14:30:53',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '38',
'name' => 'Epigenetic Antibodies Brochure',
'description' => '<p>More than in any other immuoprecipitation assays, quality antibodies are critical tools in many epigenetics experiments. Since 10 years, Diagenode has developed the most stringent quality production available on the market for antibodies exclusively focused on epigenetic uses. All our antibodies have been qualified to work in epigenetic applications.</p>',
'image_id' => null,
'type' => 'Brochure',
'url' => 'files/brochures/Epigenetic_Antibodies_Brochure.pdf',
'slug' => 'epigenetic-antibodies-brochure',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2016-06-15 11:24:06',
'created' => '2015-07-03 16:05:27',
'ProductsDocument' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '250',
'name' => 'product/antibodies/antibody.png',
'alt' => 'Mouse IgG',
'modified' => '2020-11-27 07:00:09',
'created' => '2015-07-17 10:12:18',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '2230',
'name' => 'SMAD3 Antibody SDS GB en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-GB-en-GHS_1_0.pdf',
'countries' => 'GB',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '2232',
'name' => 'SMAD3 Antibody SDS US en',
'language' => 'en',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-US-en-GHS_1_0.pdf',
'countries' => 'US',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '2227',
'name' => 'SMAD3 Antibody SDS DE de',
'language' => 'de',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-DE-de-GHS_1_0.pdf',
'countries' => 'DE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '2231',
'name' => 'SMAD3 Antibody SDS JP ja',
'language' => 'ja',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-JP-ja-GHS_1_0.pdf',
'countries' => 'JP',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '2226',
'name' => 'SMAD3 Antibody SDS BE nl',
'language' => 'nl',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-nl-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '2225',
'name' => 'SMAD3 Antibody SDS BE fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-BE-fr-GHS_1_0.pdf',
'countries' => 'BE',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '2229',
'name' => 'SMAD3 Antibody SDS FR fr',
'language' => 'fr',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-FR-fr-GHS_1_0.pdf',
'countries' => 'FR',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = false
$other_formats = array()
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'ProductsApplication' => array(
'id' => '4443',
'product_id' => '2820',
'application_id' => '32'
)
)
$slugs = array(
(int) 0 => 'immunohistochemistry'
)
$applications = array(
'id' => '32',
'position' => '10',
'parent_id' => '40',
'name' => 'IHC',
'description' => '<p>Immunohistochemistry</p>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'immunohistochemistry',
'meta_keywords' => 'immunohistochemistry,Monoclonal antibody,Polyclonal antibody',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for immunohistochemistry applications',
'meta_title' => 'Immunohistochemistry - Monoclonal antibody - Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:23:53',
'created' => '2015-07-08 13:49:03',
'locale' => 'jpn'
)
$description = '<p>Immunohistochemistry</p>'
$name = 'IHC'
$document = array(
'id' => '11',
'name' => 'Antibodies you can trust',
'description' => '<p style="text-align: justify;"><span>Epigenetic research tools have evolved over time from endpoint PCR to qPCR to the analyses of large sets of genome-wide sequencing data. ChIP sequencing (ChIP-seq) has now become the gold standard method for chromatin studies, given the accuracy and coverage scale of the approach over other methods. Successful ChIP-seq, however, requires a higher level of experimental accuracy and consistency in all steps of ChIP than ever before. Particularly crucial is the quality of ChIP antibodies. </span></p>',
'image_id' => null,
'type' => 'Poster',
'url' => 'files/posters/Antibodies_you_can_trust_Poster.pdf',
'slug' => 'antibodies-you-can-trust-poster',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2015-10-01 20:18:31',
'created' => '2015-07-03 16:05:15',
'ProductsDocument' => array(
'id' => '2132',
'product_id' => '2820',
'document_id' => '11'
)
)
$sds = array(
'id' => '2228',
'name' => 'SMAD3 Antibody SDS ES es',
'language' => 'es',
'url' => 'files/SDS/SMAD3/SDS-C15410328-SMAD3_Antibody-ES-es-GHS_1_0.pdf',
'countries' => 'ES',
'modified' => '2022-08-29 10:36:32',
'created' => '2022-08-29 10:36:32',
'ProductsSafetySheet' => array(
'id' => '3883',
'product_id' => '2820',
'safety_sheet_id' => '2228'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
×
