ZNF354C is a transcriptional repressor that inhibits endothelialangiogenic sprouting. Published: November, 2020 Abstract:
Zinc finger proteins (ZNF) are a large group of transcription factors with diverse functions. We recently discovered that endothelial cells harbour a specific mechanism to limit the action of ZNF354C, whose function in endothelial cells is unknown... Read more »
AP-1 controls the p11-dependent antidepressant response. Published: May, 2020 Abstract:
Selective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed drugs for mood disorders. While the mechanism of SSRI action is still unknown, SSRIs are thought to exert therapeutic effects by elevating extracellular serotonin level... Read more »
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Published: August, 2019 Abstract:
Sox2 is a master transcriptional regulator of embryonic development. In this study, we determined the protein interactome of Sox2 in the chromatin and nucleoplasm of mouse embryonic stem (mES) cells. Apart from canonical interactions with pluripot... Read more »
Interleukin-22 protects intestinal stem cells against genotoxic stress. Published: February, 2019 Abstract:
Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from the environment. They can induce mutations that, if they occur in epithelial stem cells, contribute... Read more »
