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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

HSV-1 infection induces a downstream shift of the +1 nucleosome
Published: March, 2025
Abstract: Herpes simplex virus 1 (HSV-1) infection induces a loss of host transcriptional activity and widespread disruption of host transcription terminatio... Read more »
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Antibody
Overlapping and distinct functions of SPT6, PNUTS, and PCF11 in reg...
Published: March, 2025
Abstract: The histone chaperone and transcription elongation factor SPT6 is integral to RNA polymerase II (RNAPII) activity. SPT6 also plays a crucial role i... Read more »
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Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ...
Published: March, 2025
Abstract: Microglial diversity arises from the interplay between inherent genetic programs and external environmental signals. However, the mechanisms by whi... Read more »
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iDeal ChIP-seq Kit for Histones
Spatially resolved genome-wide joint profiling of epigenome and tra...
Published: March, 2025
Abstract: The epigenome of a cell is tightly correlated with gene transcription, which controls cell identity and diverse biological activities. Recent advan... Read more »
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Tagmentase CUT&Tag
Transcriptional stress induces the overexpression of novel lncRNAs ...
Published: March, 2025
Abstract: Long non-coding RNAs (lncRNAs) have been shown to play a role during transcriptional regulation in response to stress. However, their function unde... Read more »
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CRISPR
Activin A activation of Smad3 mitigates innate inflammation in mous...
Published: March, 2025
Abstract: Phosphorylation of Smad3 is a critical mediator of TGF-β signaling, which plays an important role in regulating innate immune responses. Howev... Read more »
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iDeal ChIP-qPCR
ZEB1 transcription factor induces tumor cell PD-L1 expression in me...
Published: March, 2025
Abstract: Tumor cells can evade antitumor immune response by expressing the PD-L1 ligand, leading to the inhibition of PD-1-expressing T lymphocytes. The mec... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
IER3: exploring its dual function as an oncogene and tumor suppressor
Published: March, 2025
Abstract: The IER3 gene has a complex role in cancer biology, acting either as a tumor suppressor or an oncogene, depending on the cancer type. This duality ... Read more »
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iDeal ChIP-seq Kit for Histones
Recurrent patterns of widespread neuronal genomic damage shared by ...
Published: March, 2025
Abstract: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer's disease (AD) are common neurodegenerative disorders for which t... Read more »
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Tagmentase
Distinct molecular mechanisms of stress habituation in the mouse hi...
Published: March, 2025
Abstract: Chronic stress is a risk factor for neuropsychiatric disorders, making the ability to adapt to repeated stress a crucial determinant of mental heal... Read more »
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Tagmentase
Extracellular Vesicles From Follicular Fluid in Infertile Women: Si...
Published: March, 2025
Abstract: The declining birth rates and fertility challenges in Europe have intensified global concerns over rising infertility, particularly among women. Th... Read more »
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D-Plex small RNA-seq
Comprehensive molecular portrait reveals genetic diversity and dist...
Published: March, 2025
Abstract: Small intestinal neuroendocrine tumors (siNETs) are rare bowel tumors arising from malignant enteroendocrine cells, which normally regulate digesti... Read more »
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Infinium Human MethylationEPIC Array Service
Diverse somatic genomic alterations in single neurons in chronic tr...
Published: March, 2025
Abstract: Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that is linked to exposure to repetitive head impacts (RHI), yet little is kn... Read more »
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Tagmentase
Differences in maternal diet fiber content influence patterns of ge...
Published: March, 2025
Abstract: This study investigates the impact of maternal gestation diets with varying fiber contents on gene expression and chromatin accessibility in fetuse... Read more »
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ATAC-seq
H2AJ Is a Direct Androgen Receptor Target Gene That Regulates Andro...
Published: February, 2025
Abstract: Background: Prostate cancer (PCa) is a significant public health issue, particularly in developed countries. The androgen receptor (AR) plays ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Epigenetic regulation of visual system remodeling during flatfish m...
Published: February, 2025
Abstract: Flatfish metamorphosis is characterized by extensive tissue remodeling, associated with a transition from pelagic to benthic lifestyle, being the m... Read more »
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Premium RRBS Kit
Caloric restriction prevents inheritance of polycystic ovary syndro...
Published: February, 2025
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent metabolic and reproductive endocrine disorder with strong heritability. However, the independent ro... Read more »
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MagMeDIP kit
Epigenetic Regulation During Flatfish 2 Metamorphosis: Integrative ...
Published: February, 2025
Abstract: The regulation of gene expression plays a pivotal role in the complex metamorphic process of flatfishes, which oversees the dynamic alterations tha... Read more »
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Premium RRBS Kit
TGIF2 is a major regulator of neural stem cell fate and neurogenic ...
Published: February, 2025
Abstract: During brain development, neural stem cells (NSCs) must balance self-renewal with differentiation and ensure lineage progression. To identify novel... Read more »
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Microplex Library Preparation kit
CRISPR screening identifies regulators of enhancer-mediated androge...
Published: February, 2025
Abstract: Amplification of the androgen receptor (AR) locus is the most frequent alteration in metastatic castration-resistant prostate cancer (CRPC)... Read more »
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Antibody ATAC-seq
Transgenerational inheritance of diabetes susceptibility in male of...
Published: February, 2025
Abstract: Androgen exposure (AE) poses a profound health threat to women, yet its transgenerational impacts on male descendants remain unclear. Here, employi... Read more »
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MagMeDIP kit
Accelerated epigenetic aging in Huntington’s disease involves polyc...
Published: February, 2025
Abstract: Loss of epigenetic information during physiological aging compromises cellular identity, leading to de-repression of developmental genes. Here, we ... Read more »
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Antibody Microplex Library Preparation kit CUT&Tag
Combinatorial mapping of E3 ubiquitin ligases to their target subst...
Published: February, 2025
Abstract: Highlights Developed a combinatorial assay to test E3-substrate interactions at scale Identified known and unknown E3-substrate... Read more »
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Tagmentase
Using multiomic integration to improve blood biomarkers of major de...
Published: February, 2025
Abstract: Background Major depressive disorder (MDD) is a leading cause of disability, with a twofold increase in prevalence in women compared to men. Ove... Read more »
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Infinium Human MethylationEPIC Array Service
The assembly factor Reh1 is released from the ribosome during its i...
Published: February, 2025
Abstract: Assembly of functional ribosomal subunits and successfully delivering them to the translating pool is a prerequisite for protein synthesis and cell... Read more »
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D-Plex small RNA-seq
Effective in vivo binding energy landscape illustrates kinetic stab...
Published: February, 2025
Abstract: Transcription factors (TFs) such as RBPJ in Notch signaling bind to specific DNA sequences to regulate transcription. How TF-DNA binding kinetics a... Read more »
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Microplex Library Preparation kit
HDAC1 and HDAC2 are bidirectional enzymes that catalyze histone sor...
Published: January, 2025
Abstract: Reversible histone acylation is crucial for epigenetic gene expression regulation. Histone acylation is typically mediated by lysine acyltransferas... Read more »
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CUT&Tag
Chromatin environment-dependent effects of DOT1L on gene expression...
Published: January, 2025
Abstract: The H3K79 methyltransferase DOT1L is essential for multiple aspects of mammalian development where it has been shown to regulate gene expression. H... Read more »
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iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones CUT&Tag
Trithorax regulates long-term memory in Drosophila through epigenet...
Published: January, 2025
Abstract: The role of epigenetics and chromatin in the maintenance of postmitotic neuronal cell identities is not well understood. Here, we show that the his... Read more »
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Antibody Microplex Library Preparation kit True MicroChIP kit
Time-dependent chromatin maturation during 3D spheroid culture impr...
Published: January, 2025
Abstract: Non-small cell lung cancer (NSCLC) is the deadliest cancer worldwide. Therapeutic progress stagnate, highlighting the complexity to replicate NSCLC... Read more »
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ChIPmentation

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