Publications,References

Cyclin-dependent kinase inhibitor 1A mediates mouse line- and fate-...
Published: September, 2025

Abstract: Microglia, the resident macrophages in the central nervous system (CNS), have been intensively studied using rodent genetic models, including the... Read more »

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Tagmentase

Endurance training increases a ubiquitylated form of histone H3 in ...
Published: September, 2025

Abstract: At the onset of training, each exercise session transiently shifts the distribution of histone post-transcriptional modifications (HPTMs) to acti... Read more »

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Antibody

Profiling BRCA1-BRCT interactions and their functional relevance at...
Published: September, 2025

Abstract: BRCA1 (breast cancer-associated protein 1) plays a central role in homologous recombination (HR) through interactions with multiple proteins ac... Read more »

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Antibody

Spatial joint profiling of DNA methylome and transcriptome in tissues
Published: September, 2025

Abstract: The spatial resolution of omics analyses is fundamental to understanding tissue biology1-3. The capacity to spatially profile DNA methylation, ... Read more »

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Tagmentase

Developmental modulation of schizophrenia risk gene methylation in ...
Published: August, 2025

Abstract: Maternal infection during pregnancy has been shown in epidemiological studies to increase the risk of neurodevelopmental disorders, like schizo... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

Combinatorial DNMTs and EZH2 inhibition reprograms the H3K27me3 and...
Published: August, 2025

Abstract: Comprehensive epigenomic studies in multiple myeloma (MM) that unravel the connections between major epigenetic regulators, their intertwined colla... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

De novo assembly and delivery of synthetic megabase-scale human DNA...
Published: August, 2025

Abstract: Epigenetic modifications on natural chromosomes are inherited and maintained in a default state, making it challenging to remove intrinsic mark... Read more »

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Antibody

A brain-shuttled antibody targeting alpha synuclein aggregates for ...
Published: August, 2025

Abstract: Parkinson's disease and multiple system atrophy are members of a class of devastating neurodegenerative diseases called synucleinopathies, whic... Read more »

Lysine-specific demethylase 1 regulates hematopoietic stem cell exp...
Published: August, 2025

Abstract: The lysine-specific demethylase 1 (LSD1) regulates hematopoietic stem cell differentiation and has been identified as a therapeutic target in h... Read more »

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Antibody

Active chromatin marks and up-regulation of FOXC1 in uterine epithe...
Published: August, 2025

Abstract: Advanced maternal age increases the risk of pregnancy complications due, in part, to changes in the uterine environment. Here, we show that uteri... Read more »

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Antibody Microplex Library Preparation kit

Phased genome assemblies and pangenome graphs of human populations ...
Published: August, 2025

Abstract: The selection of a reference sequence in genome analysis is critical, as it serves as the foundation for all downstream analyses. Recently, the... Read more »

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Megaruptor

H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endo...
Published: August, 2025

Abstract: Endometriosis is a common gynecological condition associated with chronic inflammation, epigenetic dysregulation, and infertility. The TET1 gene,... Read more »

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Antibody

DNA methylation at retrotransposons protects the germline by preven...
Published: August, 2025

Abstract: Silencing evolutionary young retrotransposons by cytosine DNA methylation is essential for spermatogenesis, as failure to methylate their promote... Read more »

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CUT&Tag

Evidence of neuronal DNA damage in the brains of patients with Rett...
Published: August, 2025

Abstract: Rett syndrome is characterized by the postnatal loss of neurophysiological function and regression of childhood development. Because the syndrome... Read more »

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Antibody

A draft UAE-based Arab pangenome reference
Published: July, 2025

Abstract: Pangenomes provide a robust and comprehensive portrayal of genetic diversity in humans, but Arab populations remain underrepresented. We presen... Read more »

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Megaruptor

TransTag enables simple and efficient transgene mapping in zebrafis...
Published: July, 2025

Abstract: Zebrafish has become a preeminent model for developmental biology research, largely due to the ease of transgenesis. Despite widespread usage of tr... Read more »

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Tagmentase

SUMO operates from a unique long tandem repeat to keep innate immun...
Published: July, 2025

Abstract: The SUMO pathway mainly functions to repress innate immunity in myeloid cells. Inactivating sumoylation triggers a strong, noncanonical, type I... Read more »

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Antibody Microplex Library Preparation kit

Shift in the urinary metabolome associated with 2,3,7,8-tetrachloro...
Published: July, 2025

Abstract: Epidemiological evidence suggests an association between dioxin and dioxin-like compound (DLC) exposure and human liver disease. In rodents, th... Read more »

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Microplex Library Preparation kit

Genetic disruption of the baculum compromises the ability of male m...
Published: July, 2025

Abstract: The baculum, a bone in the penis of many mammal species, shows an astonishing level of morphological divergence between species. Despite hundre... Read more »

High-resolution map of the Plasmodium falciparum genome reveals MOR...
Published: July, 2025

Abstract: Genome organization plays an important role in silencing compacted, heterochromatinized genes in the most virulent human malaria parasite, Plas... Read more »

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Microplex Library Preparation kit ChIP Cross-link Gold

Somatic mutations in TBX3 promote hepatic clonal expansion by accel...
Published: July, 2025

Abstract: Somatic mutations that increase clone fitness or resist disease are positively selected, but the impact of these mutations on organismal health r... Read more »

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Antibody

Traditional Chinese Medicine Luo Tong Formula attenuates retinal in...
Published: July, 2025

Abstract: Background: Diabetic retinopathy (DR) is a leading cause of blindness in the adult population. Luo-Tong Formula (LTF), a traditional Chinese medici... Read more »

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Antibody

Liebenberg syndrome severity arises from variations in Pitx1 locus ...
Published: July, 2025

Abstract: Enhancer hijacking, a common cause of gene misregulation linked to disease, occurs when non-matching enhancers and promoters interact ectopical... Read more »

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Antibody

Dissecting the epigenetic regulation of the fetal hemoglobin genes ...
Published: July, 2025

Abstract: Beta-hemoglobinopathies are severe genetic diseases caused by mutations affecting the production of the adult β-globin chain. The clinical... Read more »

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Antibody

TP53 missense-specific transcriptional plasticity drives resistance...
Published: July, 2025

Abstract: In ~70% of patients with pancreatic ductal adenocarcinoma, the TP53 gene acquires gain-of-function (GOF) mutations leading to rapid dis... Read more »

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Microplex Library Preparation kit

Spatial profiling of chromatin accessibility in formalin-fixed para...
Published: July, 2025

Abstract: Formalin-fixed paraffin-embedded (FFPE) samples represent a vast, untapped resource for epigenomic research, yet molecular tools for deep analysi... Read more »

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Tagmentase

Constitutive expression of the transcriptional co-activator IκBζ pr...
Published: June, 2025

Abstract: IκBζ, a rather unknown co-regulator of NF-κB, can either activate or repress a subset of NF-κB target genes. While its r... Read more »

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Antibody

Quantitative measurement of phenotype dynamics during cancer drug r...
Published: June, 2025

Abstract: Cancer treatment frequently fails due to the evolution of drug-resistant cell phenotypes driven by genetic or non-genetic changes. The origin... Read more »

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Tagmentase

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells
Published: June, 2025

Abstract: Iron is an irreplaceable co-factor for metabolism. Iron deficiency affects >1 billion people and decreased iron availability impairs immunit... Read more »

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Antibody

Extrusion fountains are restricted by WAPL-dependent cohesin releas...
Published: June, 2025

Abstract: Interphase chromosomes are mainly shaped by loop extrusion and compartmentalisation mechanisms. However, their temporal component and cause-eff... Read more »

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Antibody

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