TGFα Promotes Chemoresistance of Malignant Pleural Mesothelioma. Published: June, 2020 Abstract:
: There is no standard chemotherapy for refractory or relapsing malignant pleural mesothelioma (MPM). Our previous reports nevertheless indicated that a combination of an anthracycline (doxorubicin) and a lysine deacetylase inhibitor (valproic aci... Read more »
Multisite Evaluation of Next-Generation Methods for Small RNA Quantification. Published: January, 2020 Abstract:
Small RNAs (smRNAs) are important regulators of many biologic processes and are now most frequently characterized using Illumina sequencing. However, although standard RNA sequencing library preparation has become routine in most sequencing facili... Read more »
Circulating miRNA analysis for cancer diagnostics and therapy. Published: October, 2019 Abstract:
Successful treatment of cancer depends on early diagnosis and effective monitoring of patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity and specificity to capture cancer development in its early phases a... Read more »
The sncRNA Zoo: a repository for circulating small noncoding RNAs in animals. Published: May, 2019 Abstract:
The repertoire of small noncoding RNAs (sncRNAs), particularly miRNAs, in animals is considered to be evolutionarily conserved. Studies on sncRNAs are often largely based on homology-based information, relying on genomic sequence similarity and ex... Read more »
MicroRNAs and Transplantation. Published: March, 2019 Abstract:
miRNAs, ∼20 to 22 nucleotide single-stranded RNA species that play a pivotal role in the regulation of protein-coding genes, are emerging as robust biomarkers for assessing allograft status. Herein, the authors briefly review the biogenesis an... Read more »
Directional high-throughput sequencing of RNAs without gene-specific primers. Published: October, 2018 Abstract:
Ribosomal RNA analysis is a useful tool for characterization of microbial communities. However, the lack of broad-range primers has hampered the simultaneous analysis of eukaryotic and prokaryotic members by amplicon sequencing. We present a compl... Read more »
