Notice (8): Undefined variable: solution_of_interest [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => '',
'meta_description' => '',
'meta_title' => '',
'product' => array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
[maximum depth reached]
),
'Master' => array(
[maximum depth reached]
),
'Product' => array(
[maximum depth reached]
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
),
'meta_canonical' => 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
)
$language = 'jp'
$meta_keywords = ''
$meta_description = ''
$meta_title = ''
$product = array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
'id' => '220',
'name' => 'C15310264',
'product_id' => '2906',
'modified' => '2017-10-12 16:05:52',
'created' => '2017-10-12 16:05:52'
),
'Master' => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
),
'Product' => array(
(int) 0 => array(
[maximum depth reached]
)
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '20',
'position' => '10',
'parent_id' => '40',
'name' => 'ELISA',
'description' => '<div class="row">
<div class="small-12 medium-12 large-12 columns">Enzyme-linked immunosorbent assay.</div>
</div>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'elisa-antibodies',
'meta_keywords' => ' ELISA Antibodies,Monoclonal antibody, Polyclonal antibody',
'meta_description' => 'Diagenode offers Monoclonal & Polyclonal antibodies for ELISA applications',
'meta_title' => 'ELISA Antibodies - Monoclonal & Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:21:41',
'created' => '2014-07-08 08:13:28',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '42',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-seq (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-seq-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP Sequencing applications',
'meta_title' => 'ChIP Sequencing Antibodies (ChIP-Seq) | Diagenode',
'modified' => '2016-01-20 11:06:19',
'created' => '2015-10-20 11:44:45',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '102',
'position' => '1',
'parent_id' => '4',
'name' => 'Sample size antibodies',
'description' => '<h1><strong>Validated epigenetics antibodies</strong> – care for a sample?<br /> </h1>
<p>Diagenode has partnered with leading epigenetics experts and numerous epigenetics consortiums to bring to you a validated and comprehensive collection of epigenetic antibodies. As an expert in epigenetics, we are committed to offering highly-specific antibodies validated for ChIP/ChIP-seq and many other applications. All batch-specific validation data is available on our website.<br /><a href="../categories/antibodies">Read about our expertise in antibody production</a>.</p>
<ul>
<li><strong>Focused</strong> - Diagenode's selection of antibodies is exclusively dedicated for epigenetic research. <a title="See the full collection." href="../categories/all-antibodies">See the full collection.</a></li>
<li><strong>Strict quality standards</strong> with rigorous QC and validation</li>
<li><strong>Classified</strong> based on level of validation for flexibility of application</li>
</ul>
<p>Existing sample sizes are listed below. We will soon expand our collection. Are you looking for a sample size of another antibody? Just <a href="mailto:agnieszka.zelisko@diagenode.com?Subject=Sample%20Size%20Request" target="_top">Contact us</a>.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => true,
'is_antibody' => true,
'slug' => 'sample-size-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => '5-hmC monoclonal antibody,CRISPR/Cas9 polyclonal antibody ,H3K36me3 polyclonal antibody,diagenode',
'meta_description' => 'Diagenode offers sample volume on selected antibodies for researchers to test, validate and provide confidence and flexibility in choosing from our wide range of antibodies ',
'meta_title' => 'Sample-size Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:05',
'created' => '2015-10-27 12:13:34',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 2 => array(
'id' => '21',
'position' => '20',
'parent_id' => '4',
'name' => 'Histone modifying enzymes',
'description' => '<p><span style="font-weight: 400;">Diagenode offers the large number of antibodies raised against histone modifying enzymes. The list below includes the antibodies against enzymes like: histone deacetylases, histone demethylases, histone transferases.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chromatin-modifying-proteins-histone-transferase',
'cookies_tag_id' => null,
'meta_keywords' => 'monoclonal antibodies,policlonal antibodies,Histone modifying enzymes',
'meta_description' => 'Diagenode Offers Polyclonal and Monoclonal Antibodies Against Histone Modifying Enzymes like: Histone Deacetylases, Histone Demethylases, Histone Transferases.',
'meta_title' => 'Histone modifying enzymes - Antibodies | Diagenode',
'modified' => '2019-07-04 16:19:15',
'created' => '2014-06-26 13:18:41',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 3 => array(
'id' => '127',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-grade antibodies',
'description' => '<div class="row">
<div class="small-12 columns"><center></center>
<p><br />Chromatin immunoprecipitation (<b>ChIP</b>) is a technique to study the associations of proteins with the specific genomic regions in intact cells. One of the most important steps of this protocol is the immunoprecipitation of targeted protein using the antibody specifically recognizing it. The quality of antibodies used in ChIP is essential for the success of the experiment. Diagenode offers extensively validated ChIP-grade antibodies, confirmed for their specificity, and high level of performance in ChIP. Each batch is validated, and batch-specific data are available on the website.</p>
<p></p>
</div>
</div>
<p><strong>ChIP results</strong> obtained with the antibody directed against H3K4me3 (Cat. No. <a href="../p/h3k4me3-polyclonal-antibody-premium-50-ug-50-ul">C15410003</a>). </p>
<div class="row">
<div class="small-12 medium-6 large-6 columns"><img src="https://www.diagenode.com/img/product/antibodies/C15410003-fig1-ChIP.jpg" alt="" width="400" height="315" /> </div>
<div class="small-12 medium-6 large-6 columns">
<p></p>
<p></p>
<p></p>
</div>
</div>
<p></p>
<p>Our aim at Diagenode is to offer the largest collection of highly specific <strong>ChIP-grade antibodies</strong>. We add new antibodies monthly. Find your ChIP-grade antibody in the list below and check more information about tested applications, extensive validation data, and product information.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-grade antibodies, polyclonal antibody, monoclonal antibody, Diagenode',
'meta_description' => 'Diagenode Offers Extensively Validated ChIP-Grade Antibodies, Confirmed for their Specificity, and high level of Performance in Chromatin Immunoprecipitation ChIP',
'meta_title' => 'Chromatin immunoprecipitation ChIP-grade antibodies | Diagenode',
'modified' => '2024-11-19 17:27:07',
'created' => '2017-02-14 11:16:04',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 4 => array(
'id' => '17',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-seq grade antibodies',
'description' => '<p><b>Unparalleled ChIP-Seq results with the most rigorously validated antibodies</b></p>
<p><span style="font-weight: 400;">Diagenode provides leading solutions for epigenetic research. Because ChIP-seq is a widely-used technique, we validate our antibodies in ChIP and ChIP-seq experiments (in addition to conventional methods like Western blot, Dot blot, ELISA, and immunofluorescence) to provide the highest quality antibody. We standardize our validation and production to guarantee high product quality without technical bias. Diagenode guarantees ChIP-seq grade antibody performance under our suggested conditions.</span></p>
<div class="row">
<div class="small-12 medium-9 large-9 columns">
<p><strong>ChIP-seq profile</strong> of active (H3K4me3 and H3K36me3) and inactive (H3K27me3) marks using Diagenode antibodies.</p>
<img src="https://www.diagenode.com/img/categories/antibodies/chip-seq-grade-antibodies.png" /></div>
<div class="small-12 medium-3 large-3 columns">
<p><small> ChIP was performed on sheared chromatin from 100,000 K562 cells using iDeal ChIP-seq kit for Histones (cat. No. C01010051) with 1 µg of the Diagenode antibodies against H3K27me3 (cat. No. C15410195) and H3K4me3 (cat. No. C15410003), and 0.5 µg of the antibody against H3K36me3 (cat. No. C15410192). The IP'd DNA was subsequently analysed on an Illumina Genome Analyzer. Library preparation, cluster generation and sequencing were performed according to the manufacturer's instructions. The 36 bp tags were aligned to the human genome using the ELAND algorithm. The figure shows the signal distribution along the complete sequence of human chromosome 3, a zoomin to a 10 Mb region and a further zoomin to a 1.5 Mb region. </small></p>
</div>
</div>
<p>Diagenode’s highly validated antibodies:</p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-seq-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-seq grade antibodies,polyclonal antibody,WB, ELISA, ChIP-seq (ab), ChIP-qPCR (ab)',
'meta_description' => 'Diagenode Offers Wide Range of Validated ChIP-Seq Grade Antibodies for Unparalleled ChIP-Seq Results',
'meta_title' => 'Chromatin Immunoprecipitation ChIP-Seq Grade Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:22',
'created' => '2015-02-16 02:24:01',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '1783',
'name' => 'product/antibodies/chipseq-grade-ab-icon.png',
'alt' => 'ChIP-seq Grade',
'modified' => '2020-11-27 07:04:40',
'created' => '2018-03-15 15:54:09',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '3439',
'name' => 'SDS C15310264 MLL1 Antibody US en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-US-en-GHS_2_0.pdf',
'countries' => 'US',
'modified' => '2024-01-16 13:05:05',
'created' => '2024-01-16 13:05:05',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '3437',
'name' => 'SDS C15310264 MLL1 Antibody GB en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-GB-en-GHS_2_0.pdf',
'countries' => 'GB',
'modified' => '2024-01-16 13:04:26',
'created' => '2024-01-16 13:04:26',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '3436',
'name' => 'SDS C15310264 MLL1 Antibody FR fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-FR-fr-GHS_2_0.pdf',
'countries' => 'FR',
'modified' => '2024-01-16 13:04:07',
'created' => '2024-01-16 13:04:07',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '3435',
'name' => 'SDS C15310264 MLL1 Antibody ES es',
'language' => 'es',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-ES-es-GHS_2_0.pdf',
'countries' => 'ES',
'modified' => '2024-01-16 13:03:48',
'created' => '2024-01-16 13:03:48',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '3438',
'name' => 'SDS C15310264 MLL1 Antibody JP ja',
'language' => 'ja',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-JP-ja-GHS_3_0.pdf',
'countries' => 'JP',
'modified' => '2024-01-16 13:04:44',
'created' => '2024-01-16 13:04:44',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '3434',
'name' => 'SDS C15310264 MLL1 Antibody DE de',
'language' => 'de',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-DE-de-GHS_2_0.pdf',
'countries' => 'DE',
'modified' => '2024-01-16 13:03:30',
'created' => '2024-01-16 13:03:30',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '3433',
'name' => 'SDS C15310264 MLL1 Antibody BE nl',
'language' => 'nl',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-nl-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:03:12',
'created' => '2024-01-16 13:03:12',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$meta_canonical = 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = true
$other_formats = array(
(int) 0 => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
)
$pro = array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 Antibody (sample size)',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS. Sample size available.',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'ProductsGroup' => array(
'id' => '245',
'product_id' => '2910',
'group_id' => '220'
)
)
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$other_format = array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
'id' => '4701',
'product_id' => '2910',
'application_id' => '43'
)
)
$slugs = array(
(int) 0 => 'chip-qpcr-antibodies'
)
$applications = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'locale' => 'jpn'
)
$description = ''
$name = 'ChIP-qPCR (ab)'
$document = array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
'id' => '2435',
'product_id' => '2910',
'document_id' => '971'
)
)
$sds = array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
'id' => '5578',
'product_id' => '2910',
'safety_sheet_id' => '3440'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: header [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => '',
'meta_description' => '',
'meta_title' => '',
'product' => array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
[maximum depth reached]
),
'Master' => array(
[maximum depth reached]
),
'Product' => array(
[maximum depth reached]
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
),
'meta_canonical' => 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
)
$language = 'jp'
$meta_keywords = ''
$meta_description = ''
$meta_title = ''
$product = array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
'id' => '220',
'name' => 'C15310264',
'product_id' => '2906',
'modified' => '2017-10-12 16:05:52',
'created' => '2017-10-12 16:05:52'
),
'Master' => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
),
'Product' => array(
(int) 0 => array(
[maximum depth reached]
)
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '20',
'position' => '10',
'parent_id' => '40',
'name' => 'ELISA',
'description' => '<div class="row">
<div class="small-12 medium-12 large-12 columns">Enzyme-linked immunosorbent assay.</div>
</div>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'elisa-antibodies',
'meta_keywords' => ' ELISA Antibodies,Monoclonal antibody, Polyclonal antibody',
'meta_description' => 'Diagenode offers Monoclonal & Polyclonal antibodies for ELISA applications',
'meta_title' => 'ELISA Antibodies - Monoclonal & Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:21:41',
'created' => '2014-07-08 08:13:28',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '42',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-seq (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-seq-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP Sequencing applications',
'meta_title' => 'ChIP Sequencing Antibodies (ChIP-Seq) | Diagenode',
'modified' => '2016-01-20 11:06:19',
'created' => '2015-10-20 11:44:45',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '102',
'position' => '1',
'parent_id' => '4',
'name' => 'Sample size antibodies',
'description' => '<h1><strong>Validated epigenetics antibodies</strong> – care for a sample?<br /> </h1>
<p>Diagenode has partnered with leading epigenetics experts and numerous epigenetics consortiums to bring to you a validated and comprehensive collection of epigenetic antibodies. As an expert in epigenetics, we are committed to offering highly-specific antibodies validated for ChIP/ChIP-seq and many other applications. All batch-specific validation data is available on our website.<br /><a href="../categories/antibodies">Read about our expertise in antibody production</a>.</p>
<ul>
<li><strong>Focused</strong> - Diagenode's selection of antibodies is exclusively dedicated for epigenetic research. <a title="See the full collection." href="../categories/all-antibodies">See the full collection.</a></li>
<li><strong>Strict quality standards</strong> with rigorous QC and validation</li>
<li><strong>Classified</strong> based on level of validation for flexibility of application</li>
</ul>
<p>Existing sample sizes are listed below. We will soon expand our collection. Are you looking for a sample size of another antibody? Just <a href="mailto:agnieszka.zelisko@diagenode.com?Subject=Sample%20Size%20Request" target="_top">Contact us</a>.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => true,
'is_antibody' => true,
'slug' => 'sample-size-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => '5-hmC monoclonal antibody,CRISPR/Cas9 polyclonal antibody ,H3K36me3 polyclonal antibody,diagenode',
'meta_description' => 'Diagenode offers sample volume on selected antibodies for researchers to test, validate and provide confidence and flexibility in choosing from our wide range of antibodies ',
'meta_title' => 'Sample-size Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:05',
'created' => '2015-10-27 12:13:34',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 2 => array(
'id' => '21',
'position' => '20',
'parent_id' => '4',
'name' => 'Histone modifying enzymes',
'description' => '<p><span style="font-weight: 400;">Diagenode offers the large number of antibodies raised against histone modifying enzymes. The list below includes the antibodies against enzymes like: histone deacetylases, histone demethylases, histone transferases.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chromatin-modifying-proteins-histone-transferase',
'cookies_tag_id' => null,
'meta_keywords' => 'monoclonal antibodies,policlonal antibodies,Histone modifying enzymes',
'meta_description' => 'Diagenode Offers Polyclonal and Monoclonal Antibodies Against Histone Modifying Enzymes like: Histone Deacetylases, Histone Demethylases, Histone Transferases.',
'meta_title' => 'Histone modifying enzymes - Antibodies | Diagenode',
'modified' => '2019-07-04 16:19:15',
'created' => '2014-06-26 13:18:41',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 3 => array(
'id' => '127',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-grade antibodies',
'description' => '<div class="row">
<div class="small-12 columns"><center></center>
<p><br />Chromatin immunoprecipitation (<b>ChIP</b>) is a technique to study the associations of proteins with the specific genomic regions in intact cells. One of the most important steps of this protocol is the immunoprecipitation of targeted protein using the antibody specifically recognizing it. The quality of antibodies used in ChIP is essential for the success of the experiment. Diagenode offers extensively validated ChIP-grade antibodies, confirmed for their specificity, and high level of performance in ChIP. Each batch is validated, and batch-specific data are available on the website.</p>
<p></p>
</div>
</div>
<p><strong>ChIP results</strong> obtained with the antibody directed against H3K4me3 (Cat. No. <a href="../p/h3k4me3-polyclonal-antibody-premium-50-ug-50-ul">C15410003</a>). </p>
<div class="row">
<div class="small-12 medium-6 large-6 columns"><img src="https://www.diagenode.com/img/product/antibodies/C15410003-fig1-ChIP.jpg" alt="" width="400" height="315" /> </div>
<div class="small-12 medium-6 large-6 columns">
<p></p>
<p></p>
<p></p>
</div>
</div>
<p></p>
<p>Our aim at Diagenode is to offer the largest collection of highly specific <strong>ChIP-grade antibodies</strong>. We add new antibodies monthly. Find your ChIP-grade antibody in the list below and check more information about tested applications, extensive validation data, and product information.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-grade antibodies, polyclonal antibody, monoclonal antibody, Diagenode',
'meta_description' => 'Diagenode Offers Extensively Validated ChIP-Grade Antibodies, Confirmed for their Specificity, and high level of Performance in Chromatin Immunoprecipitation ChIP',
'meta_title' => 'Chromatin immunoprecipitation ChIP-grade antibodies | Diagenode',
'modified' => '2024-11-19 17:27:07',
'created' => '2017-02-14 11:16:04',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 4 => array(
'id' => '17',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-seq grade antibodies',
'description' => '<p><b>Unparalleled ChIP-Seq results with the most rigorously validated antibodies</b></p>
<p><span style="font-weight: 400;">Diagenode provides leading solutions for epigenetic research. Because ChIP-seq is a widely-used technique, we validate our antibodies in ChIP and ChIP-seq experiments (in addition to conventional methods like Western blot, Dot blot, ELISA, and immunofluorescence) to provide the highest quality antibody. We standardize our validation and production to guarantee high product quality without technical bias. Diagenode guarantees ChIP-seq grade antibody performance under our suggested conditions.</span></p>
<div class="row">
<div class="small-12 medium-9 large-9 columns">
<p><strong>ChIP-seq profile</strong> of active (H3K4me3 and H3K36me3) and inactive (H3K27me3) marks using Diagenode antibodies.</p>
<img src="https://www.diagenode.com/img/categories/antibodies/chip-seq-grade-antibodies.png" /></div>
<div class="small-12 medium-3 large-3 columns">
<p><small> ChIP was performed on sheared chromatin from 100,000 K562 cells using iDeal ChIP-seq kit for Histones (cat. No. C01010051) with 1 µg of the Diagenode antibodies against H3K27me3 (cat. No. C15410195) and H3K4me3 (cat. No. C15410003), and 0.5 µg of the antibody against H3K36me3 (cat. No. C15410192). The IP'd DNA was subsequently analysed on an Illumina Genome Analyzer. Library preparation, cluster generation and sequencing were performed according to the manufacturer's instructions. The 36 bp tags were aligned to the human genome using the ELAND algorithm. The figure shows the signal distribution along the complete sequence of human chromosome 3, a zoomin to a 10 Mb region and a further zoomin to a 1.5 Mb region. </small></p>
</div>
</div>
<p>Diagenode’s highly validated antibodies:</p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-seq-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-seq grade antibodies,polyclonal antibody,WB, ELISA, ChIP-seq (ab), ChIP-qPCR (ab)',
'meta_description' => 'Diagenode Offers Wide Range of Validated ChIP-Seq Grade Antibodies for Unparalleled ChIP-Seq Results',
'meta_title' => 'Chromatin Immunoprecipitation ChIP-Seq Grade Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:22',
'created' => '2015-02-16 02:24:01',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '1783',
'name' => 'product/antibodies/chipseq-grade-ab-icon.png',
'alt' => 'ChIP-seq Grade',
'modified' => '2020-11-27 07:04:40',
'created' => '2018-03-15 15:54:09',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '3439',
'name' => 'SDS C15310264 MLL1 Antibody US en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-US-en-GHS_2_0.pdf',
'countries' => 'US',
'modified' => '2024-01-16 13:05:05',
'created' => '2024-01-16 13:05:05',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '3437',
'name' => 'SDS C15310264 MLL1 Antibody GB en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-GB-en-GHS_2_0.pdf',
'countries' => 'GB',
'modified' => '2024-01-16 13:04:26',
'created' => '2024-01-16 13:04:26',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '3436',
'name' => 'SDS C15310264 MLL1 Antibody FR fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-FR-fr-GHS_2_0.pdf',
'countries' => 'FR',
'modified' => '2024-01-16 13:04:07',
'created' => '2024-01-16 13:04:07',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '3435',
'name' => 'SDS C15310264 MLL1 Antibody ES es',
'language' => 'es',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-ES-es-GHS_2_0.pdf',
'countries' => 'ES',
'modified' => '2024-01-16 13:03:48',
'created' => '2024-01-16 13:03:48',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '3438',
'name' => 'SDS C15310264 MLL1 Antibody JP ja',
'language' => 'ja',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-JP-ja-GHS_3_0.pdf',
'countries' => 'JP',
'modified' => '2024-01-16 13:04:44',
'created' => '2024-01-16 13:04:44',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '3434',
'name' => 'SDS C15310264 MLL1 Antibody DE de',
'language' => 'de',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-DE-de-GHS_2_0.pdf',
'countries' => 'DE',
'modified' => '2024-01-16 13:03:30',
'created' => '2024-01-16 13:03:30',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '3433',
'name' => 'SDS C15310264 MLL1 Antibody BE nl',
'language' => 'nl',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-nl-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:03:12',
'created' => '2024-01-16 13:03:12',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$meta_canonical = 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = true
$other_formats = array(
(int) 0 => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
)
$pro = array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 Antibody (sample size)',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS. Sample size available.',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'ProductsGroup' => array(
'id' => '245',
'product_id' => '2910',
'group_id' => '220'
)
)
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$other_format = array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
'id' => '4701',
'product_id' => '2910',
'application_id' => '43'
)
)
$slugs = array(
(int) 0 => 'chip-qpcr-antibodies'
)
$applications = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'locale' => 'jpn'
)
$description = ''
$name = 'ChIP-qPCR (ab)'
$document = array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
'id' => '2435',
'product_id' => '2910',
'document_id' => '971'
)
)
$sds = array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
'id' => '5578',
'product_id' => '2910',
'safety_sheet_id' => '3440'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: message [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => '',
'meta_description' => '',
'meta_title' => '',
'product' => array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
[maximum depth reached]
),
'Master' => array(
[maximum depth reached]
),
'Product' => array(
[maximum depth reached]
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
),
'meta_canonical' => 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
)
$language = 'jp'
$meta_keywords = ''
$meta_description = ''
$meta_title = ''
$product = array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
'id' => '220',
'name' => 'C15310264',
'product_id' => '2906',
'modified' => '2017-10-12 16:05:52',
'created' => '2017-10-12 16:05:52'
),
'Master' => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
),
'Product' => array(
(int) 0 => array(
[maximum depth reached]
)
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '20',
'position' => '10',
'parent_id' => '40',
'name' => 'ELISA',
'description' => '<div class="row">
<div class="small-12 medium-12 large-12 columns">Enzyme-linked immunosorbent assay.</div>
</div>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'elisa-antibodies',
'meta_keywords' => ' ELISA Antibodies,Monoclonal antibody, Polyclonal antibody',
'meta_description' => 'Diagenode offers Monoclonal & Polyclonal antibodies for ELISA applications',
'meta_title' => 'ELISA Antibodies - Monoclonal & Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:21:41',
'created' => '2014-07-08 08:13:28',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '42',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-seq (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-seq-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP Sequencing applications',
'meta_title' => 'ChIP Sequencing Antibodies (ChIP-Seq) | Diagenode',
'modified' => '2016-01-20 11:06:19',
'created' => '2015-10-20 11:44:45',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '102',
'position' => '1',
'parent_id' => '4',
'name' => 'Sample size antibodies',
'description' => '<h1><strong>Validated epigenetics antibodies</strong> – care for a sample?<br /> </h1>
<p>Diagenode has partnered with leading epigenetics experts and numerous epigenetics consortiums to bring to you a validated and comprehensive collection of epigenetic antibodies. As an expert in epigenetics, we are committed to offering highly-specific antibodies validated for ChIP/ChIP-seq and many other applications. All batch-specific validation data is available on our website.<br /><a href="../categories/antibodies">Read about our expertise in antibody production</a>.</p>
<ul>
<li><strong>Focused</strong> - Diagenode's selection of antibodies is exclusively dedicated for epigenetic research. <a title="See the full collection." href="../categories/all-antibodies">See the full collection.</a></li>
<li><strong>Strict quality standards</strong> with rigorous QC and validation</li>
<li><strong>Classified</strong> based on level of validation for flexibility of application</li>
</ul>
<p>Existing sample sizes are listed below. We will soon expand our collection. Are you looking for a sample size of another antibody? Just <a href="mailto:agnieszka.zelisko@diagenode.com?Subject=Sample%20Size%20Request" target="_top">Contact us</a>.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => true,
'is_antibody' => true,
'slug' => 'sample-size-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => '5-hmC monoclonal antibody,CRISPR/Cas9 polyclonal antibody ,H3K36me3 polyclonal antibody,diagenode',
'meta_description' => 'Diagenode offers sample volume on selected antibodies for researchers to test, validate and provide confidence and flexibility in choosing from our wide range of antibodies ',
'meta_title' => 'Sample-size Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:05',
'created' => '2015-10-27 12:13:34',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 2 => array(
'id' => '21',
'position' => '20',
'parent_id' => '4',
'name' => 'Histone modifying enzymes',
'description' => '<p><span style="font-weight: 400;">Diagenode offers the large number of antibodies raised against histone modifying enzymes. The list below includes the antibodies against enzymes like: histone deacetylases, histone demethylases, histone transferases.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chromatin-modifying-proteins-histone-transferase',
'cookies_tag_id' => null,
'meta_keywords' => 'monoclonal antibodies,policlonal antibodies,Histone modifying enzymes',
'meta_description' => 'Diagenode Offers Polyclonal and Monoclonal Antibodies Against Histone Modifying Enzymes like: Histone Deacetylases, Histone Demethylases, Histone Transferases.',
'meta_title' => 'Histone modifying enzymes - Antibodies | Diagenode',
'modified' => '2019-07-04 16:19:15',
'created' => '2014-06-26 13:18:41',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 3 => array(
'id' => '127',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-grade antibodies',
'description' => '<div class="row">
<div class="small-12 columns"><center></center>
<p><br />Chromatin immunoprecipitation (<b>ChIP</b>) is a technique to study the associations of proteins with the specific genomic regions in intact cells. One of the most important steps of this protocol is the immunoprecipitation of targeted protein using the antibody specifically recognizing it. The quality of antibodies used in ChIP is essential for the success of the experiment. Diagenode offers extensively validated ChIP-grade antibodies, confirmed for their specificity, and high level of performance in ChIP. Each batch is validated, and batch-specific data are available on the website.</p>
<p></p>
</div>
</div>
<p><strong>ChIP results</strong> obtained with the antibody directed against H3K4me3 (Cat. No. <a href="../p/h3k4me3-polyclonal-antibody-premium-50-ug-50-ul">C15410003</a>). </p>
<div class="row">
<div class="small-12 medium-6 large-6 columns"><img src="https://www.diagenode.com/img/product/antibodies/C15410003-fig1-ChIP.jpg" alt="" width="400" height="315" /> </div>
<div class="small-12 medium-6 large-6 columns">
<p></p>
<p></p>
<p></p>
</div>
</div>
<p></p>
<p>Our aim at Diagenode is to offer the largest collection of highly specific <strong>ChIP-grade antibodies</strong>. We add new antibodies monthly. Find your ChIP-grade antibody in the list below and check more information about tested applications, extensive validation data, and product information.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-grade antibodies, polyclonal antibody, monoclonal antibody, Diagenode',
'meta_description' => 'Diagenode Offers Extensively Validated ChIP-Grade Antibodies, Confirmed for their Specificity, and high level of Performance in Chromatin Immunoprecipitation ChIP',
'meta_title' => 'Chromatin immunoprecipitation ChIP-grade antibodies | Diagenode',
'modified' => '2024-11-19 17:27:07',
'created' => '2017-02-14 11:16:04',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 4 => array(
'id' => '17',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-seq grade antibodies',
'description' => '<p><b>Unparalleled ChIP-Seq results with the most rigorously validated antibodies</b></p>
<p><span style="font-weight: 400;">Diagenode provides leading solutions for epigenetic research. Because ChIP-seq is a widely-used technique, we validate our antibodies in ChIP and ChIP-seq experiments (in addition to conventional methods like Western blot, Dot blot, ELISA, and immunofluorescence) to provide the highest quality antibody. We standardize our validation and production to guarantee high product quality without technical bias. Diagenode guarantees ChIP-seq grade antibody performance under our suggested conditions.</span></p>
<div class="row">
<div class="small-12 medium-9 large-9 columns">
<p><strong>ChIP-seq profile</strong> of active (H3K4me3 and H3K36me3) and inactive (H3K27me3) marks using Diagenode antibodies.</p>
<img src="https://www.diagenode.com/img/categories/antibodies/chip-seq-grade-antibodies.png" /></div>
<div class="small-12 medium-3 large-3 columns">
<p><small> ChIP was performed on sheared chromatin from 100,000 K562 cells using iDeal ChIP-seq kit for Histones (cat. No. C01010051) with 1 µg of the Diagenode antibodies against H3K27me3 (cat. No. C15410195) and H3K4me3 (cat. No. C15410003), and 0.5 µg of the antibody against H3K36me3 (cat. No. C15410192). The IP'd DNA was subsequently analysed on an Illumina Genome Analyzer. Library preparation, cluster generation and sequencing were performed according to the manufacturer's instructions. The 36 bp tags were aligned to the human genome using the ELAND algorithm. The figure shows the signal distribution along the complete sequence of human chromosome 3, a zoomin to a 10 Mb region and a further zoomin to a 1.5 Mb region. </small></p>
</div>
</div>
<p>Diagenode’s highly validated antibodies:</p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-seq-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-seq grade antibodies,polyclonal antibody,WB, ELISA, ChIP-seq (ab), ChIP-qPCR (ab)',
'meta_description' => 'Diagenode Offers Wide Range of Validated ChIP-Seq Grade Antibodies for Unparalleled ChIP-Seq Results',
'meta_title' => 'Chromatin Immunoprecipitation ChIP-Seq Grade Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:22',
'created' => '2015-02-16 02:24:01',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '1783',
'name' => 'product/antibodies/chipseq-grade-ab-icon.png',
'alt' => 'ChIP-seq Grade',
'modified' => '2020-11-27 07:04:40',
'created' => '2018-03-15 15:54:09',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '3439',
'name' => 'SDS C15310264 MLL1 Antibody US en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-US-en-GHS_2_0.pdf',
'countries' => 'US',
'modified' => '2024-01-16 13:05:05',
'created' => '2024-01-16 13:05:05',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '3437',
'name' => 'SDS C15310264 MLL1 Antibody GB en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-GB-en-GHS_2_0.pdf',
'countries' => 'GB',
'modified' => '2024-01-16 13:04:26',
'created' => '2024-01-16 13:04:26',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '3436',
'name' => 'SDS C15310264 MLL1 Antibody FR fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-FR-fr-GHS_2_0.pdf',
'countries' => 'FR',
'modified' => '2024-01-16 13:04:07',
'created' => '2024-01-16 13:04:07',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '3435',
'name' => 'SDS C15310264 MLL1 Antibody ES es',
'language' => 'es',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-ES-es-GHS_2_0.pdf',
'countries' => 'ES',
'modified' => '2024-01-16 13:03:48',
'created' => '2024-01-16 13:03:48',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '3438',
'name' => 'SDS C15310264 MLL1 Antibody JP ja',
'language' => 'ja',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-JP-ja-GHS_3_0.pdf',
'countries' => 'JP',
'modified' => '2024-01-16 13:04:44',
'created' => '2024-01-16 13:04:44',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '3434',
'name' => 'SDS C15310264 MLL1 Antibody DE de',
'language' => 'de',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-DE-de-GHS_2_0.pdf',
'countries' => 'DE',
'modified' => '2024-01-16 13:03:30',
'created' => '2024-01-16 13:03:30',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '3433',
'name' => 'SDS C15310264 MLL1 Antibody BE nl',
'language' => 'nl',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-nl-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:03:12',
'created' => '2024-01-16 13:03:12',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$meta_canonical = 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = true
$other_formats = array(
(int) 0 => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
)
$pro = array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 Antibody (sample size)',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS. Sample size available.',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'ProductsGroup' => array(
'id' => '245',
'product_id' => '2910',
'group_id' => '220'
)
)
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$other_format = array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
'id' => '4701',
'product_id' => '2910',
'application_id' => '43'
)
)
$slugs = array(
(int) 0 => 'chip-qpcr-antibodies'
)
$applications = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'locale' => 'jpn'
)
$description = ''
$name = 'ChIP-qPCR (ab)'
$document = array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
'id' => '2435',
'product_id' => '2910',
'document_id' => '971'
)
)
$sds = array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
'id' => '5578',
'product_id' => '2910',
'safety_sheet_id' => '3440'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: campaign_id [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL -->
<div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog">
<?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>
$viewFile = '/home/website-server/www/app/View/Products/view.ctp'
$dataForView = array(
'language' => 'jp',
'meta_keywords' => '',
'meta_description' => '',
'meta_title' => '',
'product' => array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
[maximum depth reached]
),
'Master' => array(
[maximum depth reached]
),
'Product' => array(
[maximum depth reached]
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
)
),
'Category' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
)
),
'Document' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
[maximum depth reached]
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
[maximum depth reached]
),
(int) 1 => array(
[maximum depth reached]
),
(int) 2 => array(
[maximum depth reached]
),
(int) 3 => array(
[maximum depth reached]
),
(int) 4 => array(
[maximum depth reached]
),
(int) 5 => array(
[maximum depth reached]
),
(int) 6 => array(
[maximum depth reached]
),
(int) 7 => array(
[maximum depth reached]
)
)
),
'meta_canonical' => 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
)
$language = 'jp'
$meta_keywords = ''
$meta_description = ''
$meta_title = ''
$product = array(
'Product' => array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'locale' => 'jpn'
),
'Antibody' => array(
'host' => '*****',
'id' => '507',
'name' => 'MLL1 polyclonal antibody',
'description' => 'MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.',
'clonality' => '',
'isotype' => '',
'lot' => 'A1542-001',
'concentration' => 'Not determined',
'reactivity' => 'Human. Other species not tested.',
'type' => 'Polyclonal <strong>ChIP grade, ChIP-seq grade</strong>',
'purity' => 'Whole antiserum from rabbit containing 0.05% azide.',
'classification' => 'Classic',
'application_table' => '<table>
<thead>
<tr>
<th>Applications</th>
<th>Suggested dilution/amount</th>
<th>References</th>
</tr>
</thead>
<tbody>
<tr>
<td>ChIP/ChIP-seq *</td>
<td>2 µl/ChIP</td>
<td>Fig 1, 2</td>
</tr>
<tr>
<td>ELISA</td>
<td>1:100 - 1:1,000</td>
<td>Fig 3</td>
</tr>
</tbody>
</table>
<p></p>
<p><small>*Please note that the optimal antibody amount per ChIP should be determined by the end-user. We recommend testing 1-10 µl per IP.</small></p>',
'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.',
'storage_buffer' => '',
'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.',
'uniprot_acc' => '',
'slug' => '',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2019-09-10 14:58:58',
'created' => '2017-05-08 13:53:49',
'select_label' => '507 - MLL1 polyclonal antibody (A1542-001 - Not determined - Human. Other species not tested. - Whole antiserum from rabbit containing 0.05% azide. - Rabbit)'
),
'Slave' => array(),
'Group' => array(
'Group' => array(
'id' => '220',
'name' => 'C15310264',
'product_id' => '2906',
'modified' => '2017-10-12 16:05:52',
'created' => '2017-10-12 16:05:52'
),
'Master' => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
),
'Product' => array(
(int) 0 => array(
[maximum depth reached]
)
)
),
'Related' => array(),
'Application' => array(
(int) 0 => array(
'id' => '20',
'position' => '10',
'parent_id' => '40',
'name' => 'ELISA',
'description' => '<div class="row">
<div class="small-12 medium-12 large-12 columns">Enzyme-linked immunosorbent assay.</div>
</div>',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'elisa-antibodies',
'meta_keywords' => ' ELISA Antibodies,Monoclonal antibody, Polyclonal antibody',
'meta_description' => 'Diagenode offers Monoclonal & Polyclonal antibodies for ELISA applications',
'meta_title' => 'ELISA Antibodies - Monoclonal & Polyclonal antibody | Diagenode',
'modified' => '2016-01-13 12:21:41',
'created' => '2014-07-08 08:13:28',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '42',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-seq (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-seq-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP Sequencing applications',
'meta_title' => 'ChIP Sequencing Antibodies (ChIP-Seq) | Diagenode',
'modified' => '2016-01-20 11:06:19',
'created' => '2015-10-20 11:44:45',
'ProductsApplication' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
[maximum depth reached]
)
)
),
'Category' => array(
(int) 0 => array(
'id' => '103',
'position' => '0',
'parent_id' => '4',
'name' => 'All antibodies',
'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'all-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer',
'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. Comprehensive selection of histone and non-histone Antibodies',
'meta_title' => 'Diagenode's selection of Antibodies is exclusively dedicated for Epigenetic Research | Diagenode',
'modified' => '2019-07-03 10:55:44',
'created' => '2015-11-02 14:49:22',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 1 => array(
'id' => '102',
'position' => '1',
'parent_id' => '4',
'name' => 'Sample size antibodies',
'description' => '<h1><strong>Validated epigenetics antibodies</strong> – care for a sample?<br /> </h1>
<p>Diagenode has partnered with leading epigenetics experts and numerous epigenetics consortiums to bring to you a validated and comprehensive collection of epigenetic antibodies. As an expert in epigenetics, we are committed to offering highly-specific antibodies validated for ChIP/ChIP-seq and many other applications. All batch-specific validation data is available on our website.<br /><a href="../categories/antibodies">Read about our expertise in antibody production</a>.</p>
<ul>
<li><strong>Focused</strong> - Diagenode's selection of antibodies is exclusively dedicated for epigenetic research. <a title="See the full collection." href="../categories/all-antibodies">See the full collection.</a></li>
<li><strong>Strict quality standards</strong> with rigorous QC and validation</li>
<li><strong>Classified</strong> based on level of validation for flexibility of application</li>
</ul>
<p>Existing sample sizes are listed below. We will soon expand our collection. Are you looking for a sample size of another antibody? Just <a href="mailto:agnieszka.zelisko@diagenode.com?Subject=Sample%20Size%20Request" target="_top">Contact us</a>.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => true,
'is_antibody' => true,
'slug' => 'sample-size-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => '5-hmC monoclonal antibody,CRISPR/Cas9 polyclonal antibody ,H3K36me3 polyclonal antibody,diagenode',
'meta_description' => 'Diagenode offers sample volume on selected antibodies for researchers to test, validate and provide confidence and flexibility in choosing from our wide range of antibodies ',
'meta_title' => 'Sample-size Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:05',
'created' => '2015-10-27 12:13:34',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 2 => array(
'id' => '21',
'position' => '20',
'parent_id' => '4',
'name' => 'Histone modifying enzymes',
'description' => '<p><span style="font-weight: 400;">Diagenode offers the large number of antibodies raised against histone modifying enzymes. The list below includes the antibodies against enzymes like: histone deacetylases, histone demethylases, histone transferases.</span></p>
<p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => false,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chromatin-modifying-proteins-histone-transferase',
'cookies_tag_id' => null,
'meta_keywords' => 'monoclonal antibodies,policlonal antibodies,Histone modifying enzymes',
'meta_description' => 'Diagenode Offers Polyclonal and Monoclonal Antibodies Against Histone Modifying Enzymes like: Histone Deacetylases, Histone Demethylases, Histone Transferases.',
'meta_title' => 'Histone modifying enzymes - Antibodies | Diagenode',
'modified' => '2019-07-04 16:19:15',
'created' => '2014-06-26 13:18:41',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 3 => array(
'id' => '127',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-grade antibodies',
'description' => '<div class="row">
<div class="small-12 columns"><center></center>
<p><br />Chromatin immunoprecipitation (<b>ChIP</b>) is a technique to study the associations of proteins with the specific genomic regions in intact cells. One of the most important steps of this protocol is the immunoprecipitation of targeted protein using the antibody specifically recognizing it. The quality of antibodies used in ChIP is essential for the success of the experiment. Diagenode offers extensively validated ChIP-grade antibodies, confirmed for their specificity, and high level of performance in ChIP. Each batch is validated, and batch-specific data are available on the website.</p>
<p></p>
</div>
</div>
<p><strong>ChIP results</strong> obtained with the antibody directed against H3K4me3 (Cat. No. <a href="../p/h3k4me3-polyclonal-antibody-premium-50-ug-50-ul">C15410003</a>). </p>
<div class="row">
<div class="small-12 medium-6 large-6 columns"><img src="https://www.diagenode.com/img/product/antibodies/C15410003-fig1-ChIP.jpg" alt="" width="400" height="315" /> </div>
<div class="small-12 medium-6 large-6 columns">
<p></p>
<p></p>
<p></p>
</div>
</div>
<p></p>
<p>Our aim at Diagenode is to offer the largest collection of highly specific <strong>ChIP-grade antibodies</strong>. We add new antibodies monthly. Find your ChIP-grade antibody in the list below and check more information about tested applications, extensive validation data, and product information.</p>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-grade antibodies, polyclonal antibody, monoclonal antibody, Diagenode',
'meta_description' => 'Diagenode Offers Extensively Validated ChIP-Grade Antibodies, Confirmed for their Specificity, and high level of Performance in Chromatin Immunoprecipitation ChIP',
'meta_title' => 'Chromatin immunoprecipitation ChIP-grade antibodies | Diagenode',
'modified' => '2024-11-19 17:27:07',
'created' => '2017-02-14 11:16:04',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
),
(int) 4 => array(
'id' => '17',
'position' => '10',
'parent_id' => '4',
'name' => 'ChIP-seq grade antibodies',
'description' => '<p><b>Unparalleled ChIP-Seq results with the most rigorously validated antibodies</b></p>
<p><span style="font-weight: 400;">Diagenode provides leading solutions for epigenetic research. Because ChIP-seq is a widely-used technique, we validate our antibodies in ChIP and ChIP-seq experiments (in addition to conventional methods like Western blot, Dot blot, ELISA, and immunofluorescence) to provide the highest quality antibody. We standardize our validation and production to guarantee high product quality without technical bias. Diagenode guarantees ChIP-seq grade antibody performance under our suggested conditions.</span></p>
<div class="row">
<div class="small-12 medium-9 large-9 columns">
<p><strong>ChIP-seq profile</strong> of active (H3K4me3 and H3K36me3) and inactive (H3K27me3) marks using Diagenode antibodies.</p>
<img src="https://www.diagenode.com/img/categories/antibodies/chip-seq-grade-antibodies.png" /></div>
<div class="small-12 medium-3 large-3 columns">
<p><small> ChIP was performed on sheared chromatin from 100,000 K562 cells using iDeal ChIP-seq kit for Histones (cat. No. C01010051) with 1 µg of the Diagenode antibodies against H3K27me3 (cat. No. C15410195) and H3K4me3 (cat. No. C15410003), and 0.5 µg of the antibody against H3K36me3 (cat. No. C15410192). The IP'd DNA was subsequently analysed on an Illumina Genome Analyzer. Library preparation, cluster generation and sequencing were performed according to the manufacturer's instructions. The 36 bp tags were aligned to the human genome using the ELAND algorithm. The figure shows the signal distribution along the complete sequence of human chromosome 3, a zoomin to a 10 Mb region and a further zoomin to a 1.5 Mb region. </small></p>
</div>
</div>
<p>Diagenode’s highly validated antibodies:</p>
<ul>
<li>Highly sensitive and specific</li>
<li>Cost-effective (requires less antibody per reaction)</li>
<li>Batch-specific data is available on the website</li>
<li>Expert technical support</li>
<li>Sample sizes available</li>
<li>100% satisfaction guarantee</li>
</ul>',
'no_promo' => false,
'in_menu' => true,
'online' => true,
'tabular' => false,
'hide' => true,
'all_format' => false,
'is_antibody' => true,
'slug' => 'chip-seq-grade-antibodies',
'cookies_tag_id' => null,
'meta_keywords' => 'ChIP-seq grade antibodies,polyclonal antibody,WB, ELISA, ChIP-seq (ab), ChIP-qPCR (ab)',
'meta_description' => 'Diagenode Offers Wide Range of Validated ChIP-Seq Grade Antibodies for Unparalleled ChIP-Seq Results',
'meta_title' => 'Chromatin Immunoprecipitation ChIP-Seq Grade Antibodies | Diagenode',
'modified' => '2019-07-03 10:57:22',
'created' => '2015-02-16 02:24:01',
'ProductsCategory' => array(
[maximum depth reached]
),
'CookiesTag' => array([maximum depth reached])
)
),
'Document' => array(
(int) 0 => array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
[maximum depth reached]
)
)
),
'Feature' => array(),
'Image' => array(
(int) 0 => array(
'id' => '1783',
'name' => 'product/antibodies/chipseq-grade-ab-icon.png',
'alt' => 'ChIP-seq Grade',
'modified' => '2020-11-27 07:04:40',
'created' => '2018-03-15 15:54:09',
'ProductsImage' => array(
[maximum depth reached]
)
)
),
'Promotion' => array(),
'Protocol' => array(),
'Publication' => array(),
'Testimonial' => array(),
'Area' => array(),
'SafetySheet' => array(
(int) 0 => array(
'id' => '3439',
'name' => 'SDS C15310264 MLL1 Antibody US en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-US-en-GHS_2_0.pdf',
'countries' => 'US',
'modified' => '2024-01-16 13:05:05',
'created' => '2024-01-16 13:05:05',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 1 => array(
'id' => '3437',
'name' => 'SDS C15310264 MLL1 Antibody GB en',
'language' => 'en',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-GB-en-GHS_2_0.pdf',
'countries' => 'GB',
'modified' => '2024-01-16 13:04:26',
'created' => '2024-01-16 13:04:26',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 2 => array(
'id' => '3436',
'name' => 'SDS C15310264 MLL1 Antibody FR fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-FR-fr-GHS_2_0.pdf',
'countries' => 'FR',
'modified' => '2024-01-16 13:04:07',
'created' => '2024-01-16 13:04:07',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 3 => array(
'id' => '3435',
'name' => 'SDS C15310264 MLL1 Antibody ES es',
'language' => 'es',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-ES-es-GHS_2_0.pdf',
'countries' => 'ES',
'modified' => '2024-01-16 13:03:48',
'created' => '2024-01-16 13:03:48',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 4 => array(
'id' => '3438',
'name' => 'SDS C15310264 MLL1 Antibody JP ja',
'language' => 'ja',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-JP-ja-GHS_3_0.pdf',
'countries' => 'JP',
'modified' => '2024-01-16 13:04:44',
'created' => '2024-01-16 13:04:44',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 5 => array(
'id' => '3434',
'name' => 'SDS C15310264 MLL1 Antibody DE de',
'language' => 'de',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-DE-de-GHS_2_0.pdf',
'countries' => 'DE',
'modified' => '2024-01-16 13:03:30',
'created' => '2024-01-16 13:03:30',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 6 => array(
'id' => '3433',
'name' => 'SDS C15310264 MLL1 Antibody BE nl',
'language' => 'nl',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-nl-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:03:12',
'created' => '2024-01-16 13:03:12',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
),
(int) 7 => array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
[maximum depth reached]
)
)
)
)
$meta_canonical = 'https://www.diagenode.com/jp/p/mll1-polyclonal-antibody-100-ul'
$country = 'US'
$countries_allowed = array(
(int) 0 => 'CA',
(int) 1 => 'US',
(int) 2 => 'IE',
(int) 3 => 'GB',
(int) 4 => 'DK',
(int) 5 => 'NO',
(int) 6 => 'SE',
(int) 7 => 'FI',
(int) 8 => 'NL',
(int) 9 => 'BE',
(int) 10 => 'LU',
(int) 11 => 'FR',
(int) 12 => 'DE',
(int) 13 => 'CH',
(int) 14 => 'AT',
(int) 15 => 'ES',
(int) 16 => 'IT',
(int) 17 => 'PT'
)
$outsource = true
$other_formats = array(
(int) 0 => array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
)
$pro = array(
'id' => '2910',
'antibody_id' => '507',
'name' => 'MLL1 Antibody (sample size)',
'description' => '',
'label1' => 'Validation data',
'info1' => '',
'label2' => '',
'info2' => '',
'label3' => '',
'info3' => '',
'format' => '20 µl',
'catalog_number' => 'C15310264-20',
'old_catalog_number' => '',
'sf_code' => 'C15310264-361',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '105',
'price_USD' => '115',
'price_GBP' => '100',
'price_JPY' => '16450',
'price_CNY' => '9500',
'price_AUD' => '288',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => false,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-20-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS. Sample size available.',
'modified' => '2024-01-16 13:06:25',
'created' => '2017-10-12 16:14:15',
'ProductsGroup' => array(
'id' => '245',
'product_id' => '2910',
'group_id' => '220'
)
)
$edit = ''
$testimonials = ''
$featured_testimonials = ''
$related_products = ''
$rrbs_service = array(
(int) 0 => (int) 1894,
(int) 1 => (int) 1895
)
$chipseq_service = array(
(int) 0 => (int) 2683,
(int) 1 => (int) 1835,
(int) 2 => (int) 1836,
(int) 3 => (int) 2684,
(int) 4 => (int) 1838,
(int) 5 => (int) 1839,
(int) 6 => (int) 1856
)
$labelize = object(Closure) {
}
$old_catalog_number = ''
$country_code = 'US'
$other_format = array(
'id' => '2906',
'antibody_id' => '507',
'name' => 'MLL1 Antibody',
'description' => '<p><strong>Other names:</strong> KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS</p>
<p>Polyclonal antibody raised in rabbit against human <strong>MLL1 (Mixed-Lineage Leukemia)</strong> using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'label1' => 'Validation data',
'info1' => '<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chip.png" alt="MLL1 Antibody ChIP Grade" caption="false" width="400" height="341" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 1. ChIP results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed on MV4-11 cells using the Diagenode antibody against MLL1 (Cat. No. C15310264). Sheared chromatin from 1 million cells and 2 μl of antibody were used per ChIP experiment. QPCR was performed using primers specific for the indicated genes. Figure 1 shows the recovery (the relative amount of immunoprecipitated DNA compared to input DNA).</small></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-a.png" alt="MLL1 Antibody ChIP-seq Grade" caption="false" width="700" height="83" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-b.png" alt="MLL1 Antibody for ChIP-seq" caption="false" width="700" height="149" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-c.png" alt="MLL1 Antibody for ChIP-seq assay" caption="false" width="700" height="140" /></p>
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-chipseq-D.png" alt="MLL1 Antibody validated in ChIP-seq" caption="false" width="700" height="108" /></p>
</div>
</div>
<div class="row">
<div class="small-12 columns">
<p><small><strong> Figure 2. ChIP-seq results obtained with the Diagenode antibody directed against MLL1</strong><br />ChIP was performed as described above. The IP’d DNA of 5 ChIP’s was pooled and analysed on an Illumina HiSeq. Library preparation, cluster generation and sequencing were performed according to the manufacturer’s instructions. The 50 bp tags were aligned to the human genome using the BWA algorithm. Figure 2 shows the enrichment along the complete sequence and a 700 kb region of chromosome 10 containing the JMJD1C positive control gene (fig 2A and B), and in 2 genomic regions surrounding HOX cluster on chromosome 7 and the SENP6 gene on chromosome 6 (fig 2C and D).</small></p>
</div>
</div>
<div class="row">
<div class="small-6 columns">
<p><img src="https://www.diagenode.com/img/product/antibodies/c15310264-elisa.png" alt="MLL1 Antibody ELISA validation" caption="false" width="447" height="337" /></p>
</div>
<div class="small-6 columns">
<p><small><strong> Figure 3. Determination of the antibody titer</strong><br />To determine the titer of the antibody, an ELISA was performed using a serial dilution of the Diagenode antibody directed against MLL1 (Cat. No. C15310264). The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 3), the titer of the antibody was estimated to be 1:15,100.</small></p>
</div>
</div>',
'label2' => 'Target Description',
'info2' => '<p>MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.</p>',
'label3' => '',
'info3' => '',
'format' => '100 µl',
'catalog_number' => 'C15310264',
'old_catalog_number' => '',
'sf_code' => 'C15310264-D001-001161',
'type' => 'FRE',
'search_order' => '',
'price_EUR' => '380',
'price_USD' => '380',
'price_GBP' => '340',
'price_JPY' => '59525',
'price_CNY' => '0',
'price_AUD' => '950',
'country' => 'ALL',
'except_countries' => 'Japan',
'quote' => false,
'in_stock' => false,
'featured' => false,
'no_promo' => false,
'online' => true,
'master' => true,
'last_datasheet_update' => 'May 5, 2017',
'slug' => 'mll1-polyclonal-antibody-100-ul',
'meta_title' => 'MLL1 Antibody - ChIP-seq Grade (C15310264) | Diagenode',
'meta_keywords' => '',
'meta_description' => 'MLL1 (Mixed-Lineage Leukemia) Polyclonal Antibody validated in ChIP-seq, ChIP-qPCR and ELISA. Batch-specific data available on the website. Other names: KMT2A, ALL1, CXXC7, TRX1, MLL, HRX, HTRX, HTRX1, WDSTS.',
'modified' => '2024-01-16 13:06:03',
'created' => '2017-10-12 14:43:09'
)
$img = 'banners/banner-cut_tag-chipmentation-500.jpg'
$label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>'
$application = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'ProductsApplication' => array(
'id' => '4701',
'product_id' => '2910',
'application_id' => '43'
)
)
$slugs = array(
(int) 0 => 'chip-qpcr-antibodies'
)
$applications = array(
'id' => '43',
'position' => '10',
'parent_id' => '40',
'name' => 'ChIP-qPCR (ab)',
'description' => '',
'in_footer' => false,
'in_menu' => false,
'online' => true,
'tabular' => true,
'slug' => 'chip-qpcr-antibodies',
'meta_keywords' => 'Chromatin Immunoprecipitation Sequencing,ChIP-Seq,ChIP-seq grade antibodies,DNA purification,qPCR,Shearing of chromatin',
'meta_description' => 'Diagenode offers a wide range of antibodies and technical support for ChIP-qPCR applications',
'meta_title' => 'ChIP Quantitative PCR Antibodies (ChIP-qPCR) | Diagenode',
'modified' => '2016-01-20 11:30:24',
'created' => '2015-10-20 11:45:36',
'locale' => 'jpn'
)
$description = ''
$name = 'ChIP-qPCR (ab)'
$document = array(
'id' => '971',
'name' => 'MLL1 polyclonal antibody',
'description' => '<p>Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.</p>',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet-mll1-C15310264.pdf',
'slug' => 'datasheet-mll1-c15310264',
'meta_keywords' => '',
'meta_description' => '',
'modified' => '2017-10-12 15:20:56',
'created' => '2017-10-12 15:20:56',
'ProductsDocument' => array(
'id' => '2435',
'product_id' => '2910',
'document_id' => '971'
)
)
$sds = array(
'id' => '3440',
'name' => 'SDS C15310264 MLL1 Antibody BE fr',
'language' => 'fr',
'url' => 'files/SDS/MLL1/SDS-C15310264-MLL1_Antibody-BE-fr-GHS_2_0.pdf',
'countries' => 'BE',
'modified' => '2024-01-16 13:05:24',
'created' => '2024-01-16 13:05:24',
'ProductsSafetySheet' => array(
'id' => '5578',
'product_id' => '2910',
'safety_sheet_id' => '3440'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
×
