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DNA methylation microarray

3 publications found.

Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling
Published: April, 2021
Abstract: DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution of blood DNA methylation to include 12 leukocyte subtypes (neutrophils, eosinophils, basophils, mono...
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Interplay between Histone and DNA Methylation Seen through Comparative Methylomes in Rare Mendelian Disorders
Published: April, 2021
Abstract: DNA methylation (DNAme) profiling is used to establish specific biomarkers to improve the diagnosis of patients with inherited neurodevelopmental disorders and to guide mutation screening. In the specific case of mendelian disorders of the epigene...
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Genome-wide DNA methylation and transcriptome integration reveal distinct sex differences in skeletal muscle
Published: March, 2021
Abstract: Nearly all human complex traits and diseases exhibit some degree of sex differences, and epigenetics contributes to these differences as DNA methylation shows sex differences in various tissues. However, skeletal muscle epigenetic sex differences ...
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