Publications,References

Mission SpaceX CRS-19 RRRM-1 space flight induced skin genomic plas...
Published: December, 2024

Abstract: Highlights Exposure to space environment causes genome-wide adaptive epigenetic changes Space-exposure adaptive genome-wide changes a... Read more »

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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)

The oncogenic lncRNA MIR503HG suppresses cellular senescence counte...
Published: December, 2024

Abstract: Background The androgen receptor (AR), a ligand-dependent transcription factor, plays a key role in regulating prostate cancer (PCa) growth. The n... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Independent evaluation of an 11-CpG panel for age estimation in blood
Published: December, 2024

Abstract: Highlights A set of 11 CpGs for age prediction was investigated in 148 Danish blood samples. Assay optimization improved covera... Read more »

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Premium Bisulfite Kit

Exploring the Epigenetic Landscape of Spermatozoa: Impact of Oxidat...
Published: December, 2024

Abstract: Reproductive success is dependent on gamete integrity, and oxidative stress alters male nuclei, meaning that no DNA repair is possible due to chrom... Read more »

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Antibody

PDGFRA is a conserved HAND2 effector during early cardiac development
Published: December, 2024

Abstract: The basic helix–loop–helix transcription factor HAND2 has multiple roles during vertebrate organogenesis, including cardiogenesis. Howe... Read more »

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True MicroChIP kit

EOMES establishes mesoderm and endoderm differentiation potential t...
Published: December, 2024

Abstract: Highlights Enhancer chromatin is dynamically remodeled during mesoderm/endoderm (ME) differentiation Global ME enhancer accessi... Read more »

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Antibody iDeal ChIP-seq Kit for Transcription Factors

Plasma cell-free DNA chromatin immunoprecipitation profiling depict...
Published: December, 2024

Abstract: Cell phenotype underlies prostate cancer presentation and treatment resistance and can be regulated by epigenomic features. However, the osteotropi... Read more »

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Antibody

Spatial organizations of heterochromatin underpin nuclear structura...
Published: December, 2024

Abstract: Highlights Cardiomyocytes acquire characteristic spatial organizations of heterochromatin (SOH) High levels of H2B-mCherry disr... Read more »

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ATAC-seq

Interferon-gamma rescues FK506 dampened dendritic cell calcineurin-...
Published: December, 2024

Abstract: IScience Highlights Calcineurin inhibitors block DC maturation in response to A. fumigatus Lack of DC maturation impairs T... Read more »

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Antibody IPure kit Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones

ETV2/ER71 regulates hematovascular lineage generation and vasculari...
Published: December, 2024

Abstract: Highlights Interaction of ETV2 and KDM4A decreases H3K9 trimethylation on hematovascular genes. ETV2 and KDM4A cooperatively re... Read more »

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Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services

Epi-microRNA mediated metabolic reprogramming counteracts hypoxia t...
Published: December, 2024

Abstract: To increase antibody affinity against pathogens, positively selected GC-B cells initiate cell division in the light zone (LZ) of germinal centers (... Read more »

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Microplex Library Preparation kit

NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive ge...
Published: November, 2024

Abstract: Highlights Degradation of NUP98-fp halts nascent transcription of key oncogenes within 1 h NUP98-fp loss results in accumulat... Read more »

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Antibody

HIRA protects telomeres against R-loop-induced instability in ALT c...
Published: November, 2024

Abstract: Highlights HIRA establishes greater telomeric chromatin accessibility after ATRX-DAXX loss Deposition of new H3.3 by HIRA-UBN r... Read more »

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Tagmentase

The Novel Direct AR Target Gene Annexin A2 Mediates Androgen-Induce...
Published: November, 2024

Abstract: Clinical trials for prostate cancer (PCa) patients have implemented the bipolar androgen therapy (BAT) that includes the treatment with supraphysio... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Nuclear localization of MTHFD2 is required for correct mitosis prog...
Published: November, 2024

Abstract: Subcellular compartmentalization of metabolic enzymes establishes a unique metabolic environment that elicits specific cellular functions. Indeed, ... Read more »

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Antibody

Claudin-1 as a potential marker of stress-induced premature senesce...
Published: November, 2024

Abstract: Cellular senescence, a permanent state of cell cycle arrest, can result either from external stress and is then called stress-induced premature sen... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

Engineered PsCas9 enables therapeutic genome editing in mouse liver...
Published: November, 2024

Abstract: Clinical implementation of therapeutic genome editing relies on efficient in vivo delivery and the safety of CRISPR-Cas tools. Previously, we ident... Read more »

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Tagmentase

ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophag...
Published: November, 2024

Abstract: Anti-PD-L1-based combination immunotherapy has become the first-line treatment for unresectable hepatocellular carcinoma (HCC). However, the object... Read more »

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Microplex Library Preparation kit

The molecular consequences of FOXF1 missense mutations associated w...
Published: November, 2024

Abstract: Background Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a fatal congenital lung disorder strongly associated wit... Read more »

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CUT&Tag

Atypical chemokine receptor 2 expression is directly regulated by h...
Published: November, 2024

Abstract: Lack of significant and durable clinical benefit from anti-cancer immunotherapies is partly due to the failure of cytotoxic immune cells to infiltr... Read more »

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iDeal ChIP-qPCR

ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fa...
Published: November, 2024

Abstract: SREBF1 plays the central role in lipid metabolism. It has been known that full-length SREBF1 that did not associate with SCAP (SCAP-free SREBF1) is... Read more »

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Tagmentase

Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticit...
Published: October, 2024

Abstract: Cancer cell plasticity contributes significantly to the failure of chemo- and targeted therapies in triple-negative breast cancer (TNBC). Molecular... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

A multidimensional recommendation framework for identifying biologi...
Published: October, 2024

Abstract: The quest to understand the molecular mechanisms of tumour metastasis and identify pivotal biomarkers for cancer therapy is increasing in importanc... Read more »

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Antibody

GTSF1 is required for transposon silencing in the unicellular eukar...
Published: October, 2024

Abstract: The PIWI-interacting RNA (piRNA) pathway is crucial for transposon repression and the maintenance of genomic integrity. Gametocyte-specific factor ... Read more »

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Antibody

Extracellular vesicle-mediated trafficking of molecular cues during...
Published: October, 2024

Abstract: Cellular crosstalk is an essential process influenced by numerous factors, including secreted vesicles that transfer nucleic acids, lipids, and pro... Read more »

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Microplex Library Preparation kit

COL25A1 and METAP1D DNA methylation are promising liquid biopsy epi...
Published: October, 2024

Abstract: Background Colorectal cancer is a public health issue and was the third leading cause of cancer-related death worldwide in 2022. Early diagnosis c... Read more »

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Premium Bisulfite Kit

Differential methylation of circulating free DNA assessed through c...
Published: October, 2024

Abstract: Background Recent studies have highlighted the importance of the cell-free DNA (cfDNA) methylation profile in detecting breast cancer (BC) and its... Read more »

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MagMeDIP kit

Dysregulation of pseudouridylation in small RNAs contributes to pap...
Published: October, 2024

Abstract: Background Previous studies have indicated that ψ-modified small RNAs play crucial roles in tumor metastasis. However, the ψ-modified smal... Read more »

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Antibody

Biochemical characterization of the feedforward loop between CDK1 a...
Published: October, 2024

Abstract: The complex network governing self-renewal in epidermal stem cells (EPSCs) is only partially defined. FOXM1 is one of the main players in this netw... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Epigenetic Analysis of ST3GAL3 and other Sialic Acid Metabolism Gen...
Published: October, 2024

Abstract: Research indicates that the underlying neurobiology of Attention Deficit/Hyperactivity Disorder (ADHD) may stem from a combination of genetic and e... Read more »

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Infinium Human MethylationEPIC Array Service

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