Publications
Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.
Convergent evolution of intestinal lineages in the phylum Methanoba...
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
Published: May, 2026
Abstract: Background: Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and... Read more »
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Megaruptor
MeCP2 gene dosage-dependent neurodevelopmentally restricted defects...
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Published: April, 2026
Abstract: The overexpression of MECP2 leads to severe neurological deficits in MECP2 duplication syndrome, and its dosage is considered a risk factor in ... Read more »
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Antibody CUT&Tag
Oxidative stress causes a reversible decrease of deubiquitylases ac...
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: The ubiquitin–proteasome system is essential for neuronal proteostasis, yet its function declines with age. How aging affects deubiquitylating enzy... Read more »
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Bioruptor Plus
Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinosit...
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
Published: April, 2026
Abstract: Progression through the cell cycle requires coordinated regulation of transcription, chromatin state, and cellular metabolism. While metabolic en... Read more »
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Antibody
TGF-β/SMAD4/14-3-3σ/TFEB axis promotes mesenchymal-epithelial trans...
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Published: April, 2026
Abstract: 14-3-3σ is a p53-inducible gene with tumor suppressive properties and SMAD4 is a transcription factor encoded by a tumor suppressor gene,... Read more »
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iDeal ChIP-qPCR
Population differences of chromosome 22q11.2 duplication structure ...
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
Published: April, 2026
Abstract: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is mediated by high-identity polymorphic low-copy repeats (LCRA-to-D) that have been challeng... Read more »
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Megaruptor
RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, ...
Published: April, 2026
Abstract: Pathological remodeling in cardiomyocytes during heart failure is driven by excessive activation of mTORC1. Preclinical studies in mice demonst... Read more »
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D-Plex small RNA-seq
Published: April, 2026
Abstract: Pathological remodeling in cardiomyocytes during heart failure is driven by excessive activation of mTORC1. Preclinical studies in mice demonst... Read more »
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D-Plex small RNA-seq
STAG2 loss amplifies EWS-FLI1-driven microsatellite enhancer activi...
Published: April, 2026
Abstract: Ewing sarcoma is driven by chromosomal translocations that fuse a FET RNA-binding protein to an ETS transcription factor, most commonly generatin... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Published: April, 2026
Abstract: Ewing sarcoma is driven by chromosomal translocations that fuse a FET RNA-binding protein to an ETS transcription factor, most commonly generatin... Read more »
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IPure kit iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Newly isolated human-derived Lactobacillus fermentum strain stimula...
Published: April, 2026
Abstract: The gut microbiota represents a promising target to enhance cancer immunotherapy, yet the microbial molecules mediating anti-tumor immunity remain ... Read more »
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Megaruptor
Published: April, 2026
Abstract: The gut microbiota represents a promising target to enhance cancer immunotherapy, yet the microbial molecules mediating anti-tumor immunity remain ... Read more »
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Megaruptor
A Cisplatin-Based Prodrug Inhibits Nucleotide Excision Repair Indep...
Published: April, 2026
Abstract: Cisplatin [cis-diamminedichloroplatinum(II)] is a widely used chemotherapeutic agent that induces cytotoxicity primarily through DNA damage; howeve... Read more »
Published: April, 2026
Abstract: Cisplatin [cis-diamminedichloroplatinum(II)] is a widely used chemotherapeutic agent that induces cytotoxicity primarily through DNA damage; howeve... Read more »
A single small molecule-based human embryo model reveals V-ATPase r...
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
Published: April, 2026
Abstract: Human naïve pluripotent stem cells (nPSCs) can be induced by various combinations of signaling factors to generate blastocyst-like structu... Read more »
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ATAC-seq
A novel temperate phage from Alicyclobacillus: first evidence in th...
Published: April, 2026
Abstract: Bacteriophages are increasingly explored as clean-label, environmentally friendly tools for sustainable food processing. Several phage-based produc... Read more »
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Bioruptor Plus
Published: April, 2026
Abstract: Bacteriophages are increasingly explored as clean-label, environmentally friendly tools for sustainable food processing. Several phage-based produc... Read more »
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Bioruptor Plus
Stage-specific epigenetic priming amplifies gene activation during ...
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Published: March, 2026
Abstract: Neural progenitor cells exhibit developmental plasticity as they can commit to distinct developmental trajectories. The male-specific lethal co... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Dissociation Between Metabolic Improvements and Mitochondrial Trans...
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
Published: March, 2026
Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and affecting women of reproductive age. Al... Read more »
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Premium RRBS Kit
chromIDEAS reveals epigenetic dynamics via multi-dimensional cluste...
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Published: March, 2026
Abstract: Cancer-related transcriptional dysregulation involves complex, incompletely understood epigenetic mechanisms. Chromatin states (CSs), defined by re... Read more »
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Bioruptor Plus
Exon inclusion signatures enable accurate estimation of splicing fa...
Published: March, 2026
Abstract: Splicing factors control exon inclusion in messenger RNAs, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by m... Read more »
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Bioruptor Plus
Published: March, 2026
Abstract: Splicing factors control exon inclusion in messenger RNAs, shaping transcriptome and proteome diversity. Their catalytic activity is regulated by m... Read more »
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Bioruptor Plus
A repeat expansion in GOLGA8A is a major risk factor for atypical f...
Published: March, 2026
Abstract: Atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions (aFTLD-U) is neuropathologically characterized by aggregation of the ... Read more »
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Megaruptor
Published: March, 2026
Abstract: Atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions (aFTLD-U) is neuropathologically characterized by aggregation of the ... Read more »
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Megaruptor
The effects of ingested cellulose nanomaterials on DNA methylation ...
Published: March, 2026
Abstract: Background: Cellulose nanomaterials (CNMs) are emerging materials under development for various applications in biomedicine and the food indus... Read more »
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Premium RRBS Kit
Published: March, 2026
Abstract: Background: Cellulose nanomaterials (CNMs) are emerging materials under development for various applications in biomedicine and the food indus... Read more »
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Premium RRBS Kit
Proteomic landscape of Ewing sarcoma primary tumors and metastases
Published: March, 2026
Abstract: Ewing sarcoma (EWS), a rare pediatric bone tumor, poses unique therapeutic challenges due to its distinct microenvironment and limited molecular un... Read more »
Published: March, 2026
Abstract: Ewing sarcoma (EWS), a rare pediatric bone tumor, poses unique therapeutic challenges due to its distinct microenvironment and limited molecular un... Read more »
Epithelial sensing of vitamin A shapes intestinal antimicrobial def...
Published: March, 2026
Abstract: Vitamin A is a central regulator of intestinal adaptive immunity, but its role in innate immunity is less defined. Antimicrobial proteins form a ch... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Published: March, 2026
Abstract: Vitamin A is a central regulator of intestinal adaptive immunity, but its role in innate immunity is less defined. Antimicrobial proteins form a ch... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Genome-wide discovery of cis-regulatory elements in a large genome
Published: March, 2026
Abstract: Identifying non-coding regulatory elements in the genome poses a challenge in most organisms. Classical methods rely on trial and error to test t... Read more »
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Tagmentase
Published: March, 2026
Abstract: Identifying non-coding regulatory elements in the genome poses a challenge in most organisms. Classical methods rely on trial and error to test t... Read more »
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Tagmentase
Global mapping of circRNA-target RNA interactions reveal P-body-med...
Published: March, 2026
Abstract: Circular RNAs (circRNAs) are primarily produced through pre-mRNA back-splicing, yet their target repertoire and functional mechanisms remain elus... Read more »
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D-Plex small RNA-seq
Published: March, 2026
Abstract: Circular RNAs (circRNAs) are primarily produced through pre-mRNA back-splicing, yet their target repertoire and functional mechanisms remain elus... Read more »
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D-Plex small RNA-seq
Direct interaction of ribosomes with postsynaptic proteins gives ri...
Published: February, 2026
Abstract: Ribosomes and thousands of mRNAs are localized near synapses to support local protein synthesis. Little is known, however, about how ribosomes ar... Read more »
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D-Plex small RNA-seq
Published: February, 2026
Abstract: Ribosomes and thousands of mRNAs are localized near synapses to support local protein synthesis. Little is known, however, about how ribosomes ar... Read more »
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D-Plex small RNA-seq
Translational buffering tunes gene expression in mice and humans
Published: February, 2026
Abstract: Background: Translational buffering refers to the regulation of ribosome occupancy to offset the effects of transcriptional variation. While p... Read more »
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D-Plex small RNA-seq
Published: February, 2026
Abstract: Background: Translational buffering refers to the regulation of ribosome occupancy to offset the effects of transcriptional variation. While p... Read more »
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D-Plex small RNA-seq
SIRT1 mediates brain metabolic and developmental consequences of me...
Published: February, 2026
Abstract: Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological d... Read more »
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Published: February, 2026
Abstract: Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological d... Read more »
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Premium RRBS Kit
Functional dissection of complex trait variants at single-nucleotid...
Published: February, 2026
Abstract: Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core problem in human genetics1-5. Most of thes... Read more »
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Tagmentase
Published: February, 2026
Abstract: Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core problem in human genetics1-5. Most of thes... Read more »
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Tagmentase
Repeat-rich RNA guides repetitive genomic elements into biomolecula...
Published: February, 2026
Abstract: Biomolecular condensation is a pivotal mechanism in chromatin organization and nuclear compartmentalization. However, the molecular mechanism t... Read more »
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Tagmentase
Published: February, 2026
Abstract: Biomolecular condensation is a pivotal mechanism in chromatin organization and nuclear compartmentalization. However, the molecular mechanism t... Read more »
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Tagmentase
Genetic regulation across germline and somatic variation on the Y c...
Published: February, 2026
Abstract: Our understanding of the biological role of the Y chromosome remains limited. Here, we systematically profile germline Y haplogroups and somatic lo... Read more »
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Megaruptor
Published: February, 2026
Abstract: Our understanding of the biological role of the Y chromosome remains limited. Here, we systematically profile germline Y haplogroups and somatic lo... Read more »
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Megaruptor
Methylome and transcriptome responses to feed stress induced by low...
Published: February, 2026
Abstract: Background Poultry farming provides an important source of protein for human consumption around the world. Improving chicken adaptation to changin... Read more »
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Premium RRBS Kit
Published: February, 2026
Abstract: Background Poultry farming provides an important source of protein for human consumption around the world. Improving chicken adaptation to changin... Read more »
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Premium RRBS Kit
Hypoxic stress granules trigger immunogenic dormancy in lung cancer
Published: February, 2026
Abstract: Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for eff... Read more »
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Antibody
Published: February, 2026
Abstract: Induction of the MHC class I antigen processing and presentation pathway (C1APP) is a critical part of the IFN-γ response necessary for eff... Read more »
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Antibody