| Bioruptor® Pico DNA QC kit manual MANUAL We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your ... | Download |
We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your Bioruptor® Pico and to figure out the right time for servicing. After the sonication, if your QC does not reach our standards, please, contact Diagenode for recommendations. However, if your QC passes, we wish you every success with your Bioruptor®.
| Bioruptor® Pico DNA QC kit manual MANUAL We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your ... | Download |
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The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa fa-arrow-circle-right"></i> <a href="https://www.diagenode.com/pages/chromatin-prep-easyshear-kit-guide">Read more</a></h3> </div> <p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> </p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'format' => '1 unit', 'catalog_number' => 'B01080010', 'old_catalog_number' => '', 'sf_code' => 'B01080010-', 'type' => 'ACC', 'search_order' => '00-Machine', 'price_EUR' => '27000', 'price_USD' => '30000', 'price_GBP' => '23500', 'price_JPY' => '4229550', 'price_CNY' => '/', 'price_AUD' => '75000', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => true, 'in_stock' => false, 'featured' => true, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '', 'slug' => 'bioruptorpico2', 'meta_title' => 'Bioruptor® Pico sonication device', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Pico sonication device', 'modified' => '2024-06-14 15:28:50', 'created' => '2020-01-09 16:27:17', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ) ), 'Application' => array(), 'Category' => array( (int) 0 => array( 'id' => '40', 'position' => '1', 'parent_id' => '6', 'name' => 'Bioruptor<sup>®</sup> Pico accessories', 'description' => '<p>All you need for the smooth running of the Bioruptor<sup>®</sup> Pico. 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value="AO">Angola</option> <option value="AI">Anguilla</option> <option value="AQ">Antarctica</option> <option value="AG">Antigua and Barbuda</option> <option value="AR">Argentina</option> <option value="AM">Armenia</option> <option value="AW">Aruba</option> <option value="AU">Australia</option> <option value="AT">Austria</option> <option value="AZ">Azerbaijan</option> <option value="BS">Bahamas</option> <option value="BH">Bahrain</option> <option value="BD">Bangladesh</option> <option value="BB">Barbados</option> <option value="BY">Belarus</option> <option value="BE">Belgium</option> <option value="BZ">Belize</option> <option value="BJ">Benin</option> <option value="BM">Bermuda</option> <option value="BT">Bhutan</option> <option value="BO">Bolivia</option> <option value="BQ">Bonaire, Sint Eustatius and Saba</option> <option value="BA">Bosnia and Herzegovina</option> <option value="BW">Botswana</option> <option value="BV">Bouvet Island</option> <option value="BR">Brazil</option> <option value="IO">British Indian Ocean Territory</option> <option value="BN">Brunei Darussalam</option> <option value="BG">Bulgaria</option> <option value="BF">Burkina Faso</option> <option value="BI">Burundi</option> <option value="KH">Cambodia</option> <option value="CM">Cameroon</option> <option value="CA">Canada</option> <option value="CV">Cape Verde</option> <option value="KY">Cayman Islands</option> <option value="CF">Central African Republic</option> <option value="TD">Chad</option> <option value="CL">Chile</option> <option value="CN">China</option> <option value="CX">Christmas Island</option> <option value="CC">Cocos (Keeling) Islands</option> <option value="CO">Colombia</option> <option value="KM">Comoros</option> <option value="CG">Congo</option> <option value="CD">Congo, The Democratic Republic of the</option> <option value="CK">Cook Islands</option> <option value="CR">Costa Rica</option> <option value="CI">Côte d'Ivoire</option> <option value="HR">Croatia</option> <option value="CU">Cuba</option> <option value="CW">Curaçao</option> <option value="CY">Cyprus</option> <option value="CZ">Czech Republic</option> <option value="DK">Denmark</option> <option value="DJ">Djibouti</option> <option value="DM">Dominica</option> <option value="DO">Dominican Republic</option> <option value="EC">Ecuador</option> <option value="EG">Egypt</option> <option value="SV">El Salvador</option> <option value="GQ">Equatorial Guinea</option> <option value="ER">Eritrea</option> <option value="EE">Estonia</option> <option value="ET">Ethiopia</option> <option value="FK">Falkland Islands (Malvinas)</option> <option value="FO">Faroe Islands</option> <option value="FJ">Fiji</option> <option value="FI">Finland</option> <option value="FR">France</option> <option value="GF">French Guiana</option> <option value="PF">French Polynesia</option> <option value="TF">French Southern Territories</option> <option value="GA">Gabon</option> <option value="GM">Gambia</option> <option value="GE">Georgia</option> <option value="DE">Germany</option> <option value="GH">Ghana</option> <option value="GI">Gibraltar</option> <option value="GR">Greece</option> <option value="GL">Greenland</option> <option value="GD">Grenada</option> <option value="GP">Guadeloupe</option> <option value="GU">Guam</option> <option value="GT">Guatemala</option> <option value="GG">Guernsey</option> <option value="GN">Guinea</option> <option value="GW">Guinea-Bissau</option> <option value="GY">Guyana</option> <option value="HT">Haiti</option> <option value="HM">Heard Island and McDonald Islands</option> <option value="VA">Holy See (Vatican City State)</option> <option value="HN">Honduras</option> <option value="HK">Hong Kong</option> <option value="HU">Hungary</option> <option value="IS">Iceland</option> <option value="IN">India</option> <option value="ID">Indonesia</option> <option value="IR">Iran, Islamic Republic of</option> <option value="IQ">Iraq</option> <option value="IE">Ireland</option> <option value="IM">Isle of Man</option> <option value="IL">Israel</option> <option value="IT">Italy</option> <option value="JM">Jamaica</option> <option value="JP">Japan</option> <option value="JE">Jersey</option> <option value="JO">Jordan</option> <option value="KZ">Kazakhstan</option> <option value="KE">Kenya</option> <option value="KI">Kiribati</option> <option value="KP">Korea, Democratic People's Republic of</option> <option value="KR">Korea, Republic of</option> <option value="KW">Kuwait</option> <option value="KG">Kyrgyzstan</option> <option value="LA">Lao People's Democratic Republic</option> <option value="LV">Latvia</option> <option value="LB">Lebanon</option> <option value="LS">Lesotho</option> <option value="LR">Liberia</option> <option value="LY">Libya</option> <option value="LI">Liechtenstein</option> <option value="LT">Lithuania</option> <option value="LU">Luxembourg</option> <option value="MO">Macao</option> <option value="MK">Macedonia, Republic of</option> <option 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columns"> <input name="data[Quote][state]" id="state-3046" maxlength="3" type="text"/><br /> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Email <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][email]" placeholder="email@address.com" maxlength="255" type="email" id="QuoteEmail" required="required"/> </div> </div> <div class="row collapse" id="email_v"> <div class="small-3 large-2 columns"> <span class="prefix">Email verification<sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][email_v]" autocomplete="nope" type="text" id="QuoteEmailV"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Comment</span> </div> <div class="small-9 large-10 columns"> <textarea name="data[Quote][comment]" placeholder="Additional comments" cols="30" rows="6" id="QuoteComment"></textarea> </div> </div> <!------------SERVICES PARTICULAR FORM START----------------> <!------------DATA TO POPULATE REGARDING SPECIFIC SERVICES-----> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <div class="recaptcha"><div id="recaptcha67348ec94d228"></div></div> </div> </div> <br /> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <button id="submit_btn-3046" class="alert button expand" form="Quote-3046" type="submit">Contact me</button> </div> </div> </form><script> var pardotFormHandlerURL = 'https://go.diagenode.com/l/928883/2022-10-10/36b1c'; function postToPardot(formAction, id) { $('#pardot-form-handler').load(function(){ $('#Quote-' + id).attr('action', formAction); $('#Quote-' + id).submit(); }); $('#pardot-form-handler').attr('src', pardotFormHandlerURL + '?' + $('#Quote-' + id).serialize()); } $(document).ready(function() { 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(SA)</option><option value="SH">Schleswig-Holstein (SH)</option><option value="TH">Thüringen</option></select>'); $("#Quote-3046 #state-3046").parent().parent().show(); } else { $("#Quote-3046 #state-3046").parent().parent().hide(); $("#Quote-3046 #state-3046").replaceWith('<input name="data[Quote][state]" maxlength="255" type="text" id="state-3046" value="">'); } }); </script> <a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: QUOTE MODAL --><a href="#" id="bioruptorpico2" data-reveal-id="quoteModal-3046" class="quote_btn" style="color:#B21329"><i class="fa fa-info-circle"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Pico sonication device</h6> </div> </div> </li> ' $related = array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa 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However, if your QC passes, we wish you every success with your Bioruptor</span><span>®</span><span>.</span></p>', 'label1' => '', 'info1' => '', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '1 unit', 'catalog_number' => 'C40010002', 'old_catalog_number' => '', 'sf_code' => 'C40010002-', 'type' => 'REF', 'search_order' => '01-Accessory', 'price_EUR' => '125', 'price_USD' => '135', 'price_GBP' => '115', 'price_JPY' => '19580', 'price_CNY' => '', 'price_AUD' => '338', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '0000-00-00', 'slug' => 'Bioruptor-Pico-DNA-QC-kit', 'meta_title' => 'Bioruptor® Pico DNA QC kit', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Pico DNA QC kit', 'modified' => '2020-11-17 11:26:47', 'created' => '2016-09-21 17:04:22', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => null, 'name' => null, 'description' => null, 'clonality' => null, 'isotype' => null, 'lot' => null, 'concentration' => null, 'reactivity' => null, 'type' => null, 'purity' => null, 'classification' => null, 'application_table' => null, 'storage_conditions' => null, 'storage_buffer' => null, 'precautions' => null, 'uniprot_acc' => null, 'slug' => null, 'meta_keywords' => null, 'meta_description' => null, 'modified' => null, 'created' => null, 'select_label' => null ), 'Slave' => array(), 'Group' => array(), 'Related' => array( (int) 0 => array( 'id' => '1809', 'antibody_id' => null, 'name' => '0.5/0.65 ml tube holder for Bioruptor<sup>®</sup> Standard & Plus', 'description' => '<p><span>The attachment for 0.5 ml (Standard/Plus) tubes has been especially designed for being used with the Bioruptor® sonication device. It allows for reproducible sonication of up to 12 samples at a time.</span></p>', 'label1' => '', 'info1' => '', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '1 pack', 'catalog_number' => 'B01200043', 'old_catalog_number' => 'UCD-pack 0.5', 'sf_code' => 'B01200043-', 'type' => 'ACC', 'search_order' => '01-Accessory', 'price_EUR' => '1300', 'price_USD' => '1800', 'price_GBP' => '1150', 'price_JPY' => '203645', 'price_CNY' => '', 'price_AUD' => '4500', 'country' => 'ALL', 'except_countries' => 'Japan', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '0000-00-00', 'slug' => '0-5-0-65-ml-tube-holder-for-bioruptor-standard-plus-pico-1-pack', 'meta_title' => '0.5/0.65 ml tube holder for Bioruptor® Standard & Plus & Pico', 'meta_keywords' => '', 'meta_description' => '0.5/0.65 ml tube holder for Bioruptor® Standard & Plus & Pico', 'modified' => '2020-03-09 09:53:05', 'created' => '2015-06-29 14:08:20', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ), (int) 1 => array( 'id' => '2835', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Plus DNA QC kit', 'description' => '<p>We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your <strong>Bioruptor</strong><span><strong>® Plus/Standard</strong> </span><span>and to figure out the right time for servicing. 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However, if your QC pass, we wish you every success with your Bioruptor</span><span>®</span><span>.</span></p>', 'label1' => '', 'info1' => '', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '1 unit', 'catalog_number' => 'C40010001', 'old_catalog_number' => '', 'sf_code' => 'C40010001-', 'type' => 'REF', 'search_order' => '01-Accessory', 'price_EUR' => '125', 'price_USD' => '135', 'price_GBP' => '115', 'price_JPY' => '19580', 'price_CNY' => '', 'price_AUD' => '338', 'country' => 'ALL', 'except_countries' => 'Japan', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '0000-00-00', 'slug' => 'Bioruptor-Plus-DNA-QC-kit', 'meta_title' => 'Bioruptor® Plus DNA QC kit', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Plus DNA QC kit', 'modified' => '2018-01-26 10:57:27', 'created' => '2016-09-21 16:49:44', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ), (int) 2 => array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa fa-arrow-circle-right"></i> <a href="https://www.diagenode.com/pages/chromatin-prep-easyshear-kit-guide">Read more</a></h3> </div> <p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> </p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'format' => '1 unit', 'catalog_number' => 'B01080010', 'old_catalog_number' => '', 'sf_code' => 'B01080010-', 'type' => 'ACC', 'search_order' => '00-Machine', 'price_EUR' => '27000', 'price_USD' => '30000', 'price_GBP' => '23500', 'price_JPY' => '4229550', 'price_CNY' => '/', 'price_AUD' => '75000', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => true, 'in_stock' => false, 'featured' => true, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '', 'slug' => 'bioruptorpico2', 'meta_title' => 'Bioruptor® Pico sonication device', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Pico sonication device', 'modified' => '2024-06-14 15:28:50', 'created' => '2020-01-09 16:27:17', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ) ), 'Application' => array(), 'Category' => array( (int) 0 => array( 'id' => '40', 'position' => '1', 'parent_id' => '6', 'name' => 'Bioruptor<sup>®</sup> Pico accessories', 'description' => '<p>All you need for the smooth running of the Bioruptor<sup>®</sup> Pico. 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Plus DNA QC kit</strong> to my shopping cart.</p> <div class="row"> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="checkout" id="checkout" value="checkout" type="submit">Checkout</button> </div> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="keepshop" id="keepshop" type="submit">Keep shopping</button> </div> </div> </div> </div> </form><a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: ADD TO CART MODAL --><a href="#" id="Bioruptor-Plus-DNA-QC-kit" data-reveal-id="cartModal-2835" class="" style="color:#B21329"><i class="fa fa-cart-plus"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Plus DNA QC kit</h6> </div> </div> </li> <li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/bioruptorpico2"><img src="/img/product/shearing_technologies/B01080000-1.jpg" alt="Bioruptor Pico" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">B01080010</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: QUOTE MODAL --><div id="quoteModal-3046" class="reveal-modal small" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <h3>Get a quote</h3><p class="lead">You are about to request a quote for <strong>Bioruptor<sup>®</sup> Pico sonication device</strong>. Fill out the form below and we will be in touch with you very soon.</p><p><small>All <span style="font-size:16px;color:red;">*</span> fields are mandatory</small></p> </div> </div> <form action="/en/quotes/quote?id=3046" id="Quote-3046" class="quote" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Quote][product_id]" value="3046" id="QuoteProductId"/><input type="hidden" name="data[Quote][formLoaded6tY4bPYk]" value="TnRBbnZnc21IeGdtOURiRm9OVHBWUT09" id="QuoteFormLoaded6tY4bPYk"/><input type="hidden" name="data[Quote][product_rfq_tag]" value="bioruptorpico2" id="QuoteProductRfqTag"/><input type="hidden" name="data[Quote][source_quote]" value="modal quote" id="QuoteSourceQuote"/> <div class="row collapse"> <h2>Contact Information</h2> <div class="small-3 large-2 columns"> <span class="prefix">First name <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 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<input name="data[Quote][phone_number]" placeholder="+1 862 209-4680" maxlength="255" type="text" id="QuotePhoneNumber"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">City</span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][city]" placeholder="Denville" maxlength="255" type="text" id="QuoteCity"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Country <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <select name="data[Quote][country]" required="required" class="triggers" id="country_selector_quote-3046"> <option value="">-- select a country --</option> <option value="AF">Afghanistan</option> <option value="AX">Åland Islands</option> <option value="AL">Albania</option> <option value="DZ">Algeria</option> <option value="AS">American Samoa</option> <option value="AD">Andorra</option> <option 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id="QuoteComment"></textarea> </div> </div> <!------------SERVICES PARTICULAR FORM START----------------> <!------------DATA TO POPULATE REGARDING SPECIFIC SERVICES-----> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <div class="recaptcha"><div id="recaptcha67348ec94d228"></div></div> </div> </div> <br /> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <button id="submit_btn-3046" class="alert button expand" form="Quote-3046" type="submit">Contact me</button> </div> </div> </form><script> var pardotFormHandlerURL = 'https://go.diagenode.com/l/928883/2022-10-10/36b1c'; function postToPardot(formAction, id) { $('#pardot-form-handler').load(function(){ $('#Quote-' + id).attr('action', formAction); $('#Quote-' + id).submit(); }); $('#pardot-form-handler').attr('src', pardotFormHandlerURL + '?' + $('#Quote-' + id).serialize()); } $(document).ready(function() { 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(SA)</option><option value="SH">Schleswig-Holstein (SH)</option><option value="TH">Thüringen</option></select>'); $("#Quote-3046 #state-3046").parent().parent().show(); } else { $("#Quote-3046 #state-3046").parent().parent().hide(); $("#Quote-3046 #state-3046").replaceWith('<input name="data[Quote][state]" maxlength="255" type="text" id="state-3046" value="">'); } }); </script> <a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: QUOTE MODAL --><a href="#" id="bioruptorpico2" data-reveal-id="quoteModal-3046" class="quote_btn" style="color:#B21329"><i class="fa fa-info-circle"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Pico sonication device</h6> </div> </div> </li> ' $related = array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa 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It allows for reproducible sonication of up to 12 samples at a time.</span></p>', 'label1' => '', 'info1' => '', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '1 pack', 'catalog_number' => 'B01200043', 'old_catalog_number' => 'UCD-pack 0.5', 'sf_code' => 'B01200043-', 'type' => 'ACC', 'search_order' => '01-Accessory', 'price_EUR' => '1300', 'price_USD' => '1800', 'price_GBP' => '1150', 'price_JPY' => '203645', 'price_CNY' => '', 'price_AUD' => '4500', 'country' => 'ALL', 'except_countries' => 'Japan', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '0000-00-00', 'slug' => '0-5-0-65-ml-tube-holder-for-bioruptor-standard-plus-pico-1-pack', 'meta_title' => '0.5/0.65 ml tube holder for Bioruptor® Standard & Plus & Pico', 'meta_keywords' => '', 'meta_description' => '0.5/0.65 ml tube holder for Bioruptor® Standard & Plus & Pico', 'modified' => '2020-03-09 09:53:05', 'created' => '2015-06-29 14:08:20', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ), (int) 1 => array( 'id' => '2835', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Plus DNA QC kit', 'description' => '<p>We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your <strong>Bioruptor</strong><span><strong>® Plus/Standard</strong> </span><span>and to figure out the right time for servicing. After the sonication, if your QC does not reach our standards, please, contact Diagenode for recommendations. However, if your QC pass, we wish you every success with your Bioruptor</span><span>®</span><span>.</span></p>', 'label1' => '', 'info1' => '', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '1 unit', 'catalog_number' => 'C40010001', 'old_catalog_number' => '', 'sf_code' => 'C40010001-', 'type' => 'REF', 'search_order' => '01-Accessory', 'price_EUR' => '125', 'price_USD' => '135', 'price_GBP' => '115', 'price_JPY' => '19580', 'price_CNY' => '', 'price_AUD' => '338', 'country' => 'ALL', 'except_countries' => 'Japan', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '0000-00-00', 'slug' => 'Bioruptor-Plus-DNA-QC-kit', 'meta_title' => 'Bioruptor® Plus DNA QC kit', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Plus DNA QC kit', 'modified' => '2018-01-26 10:57:27', 'created' => '2016-09-21 16:49:44', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ), (int) 2 => array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa fa-arrow-circle-right"></i> <a href="https://www.diagenode.com/pages/chromatin-prep-easyshear-kit-guide">Read more</a></h3> </div> <p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> </p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'format' => '1 unit', 'catalog_number' => 'B01080010', 'old_catalog_number' => '', 'sf_code' => 'B01080010-', 'type' => 'ACC', 'search_order' => '00-Machine', 'price_EUR' => '27000', 'price_USD' => '30000', 'price_GBP' => '23500', 'price_JPY' => '4229550', 'price_CNY' => '/', 'price_AUD' => '75000', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => true, 'in_stock' => false, 'featured' => true, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '', 'slug' => 'bioruptorpico2', 'meta_title' => 'Bioruptor® Pico sonication device', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Pico sonication device', 'modified' => '2024-06-14 15:28:50', 'created' => '2020-01-09 16:27:17', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ) ), 'Application' => array(), 'Category' => array( (int) 0 => array( 'id' => '40', 'position' => '1', 'parent_id' => '6', 'name' => 'Bioruptor<sup>®</sup> Pico accessories', 'description' => '<p>All you need for the smooth running of the Bioruptor<sup>®</sup> Pico. 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aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <form action="/en/carts/add/1809" id="CartAdd/1809Form" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Cart][product_id]" value="1809" id="CartProductId"/> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <p>Add <input name="data[Cart][quantity]" placeholder="1" value="1" min="1" style="width:60px;display:inline" type="number" id="CartQuantity" required="required"/> <strong> 0.5/0.65 ml tube holder for Bioruptor<sup>®</sup> Standard & Plus</strong> to my shopping cart.</p> <div class="row"> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('0.5/0.65 ml tube holder for Bioruptor<sup>®</sup> Standard & Plus', 'B01200043', '1800', $('#CartQuantity').val());" name="checkout" id="checkout" value="checkout" type="submit">Checkout</button> </div> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('0.5/0.65 ml tube holder for Bioruptor<sup>®</sup> Standard & Plus', 'B01200043', '1800', $('#CartQuantity').val());" name="keepshop" id="keepshop" type="submit">Keep shopping</button> </div> </div> </div> </div> </form><a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: ADD TO CART MODAL --><a href="#" id="0-5-0-65-ml-tube-holder-for-bioruptor-standard-plus-pico-1-pack" data-reveal-id="cartModal-1809" class="" style="color:#B21329"><i class="fa fa-cart-plus"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">0.5/0.65 ml tube holder for Bioruptor® Stan...</h6> </div> </div> </li> <li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/Bioruptor-Plus-DNA-QC-kit"><img src="/img/product/kits/dnaqckit.jpg" alt="dna qc kit" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">C40010001</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: ADD TO CART MODAL --><div id="cartModal-2835" class="reveal-modal small" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <form action="/en/carts/add/2835" id="CartAdd/2835Form" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Cart][product_id]" value="2835" id="CartProductId"/> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <p>Add <input name="data[Cart][quantity]" placeholder="1" value="1" min="1" style="width:60px;display:inline" type="number" id="CartQuantity" required="required"/> <strong> Bioruptor<sup>®</sup> Plus DNA QC kit</strong> to my shopping cart.</p> <div class="row"> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="checkout" id="checkout" value="checkout" type="submit">Checkout</button> </div> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="keepshop" id="keepshop" type="submit">Keep shopping</button> </div> </div> </div> </div> </form><a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: ADD TO CART MODAL --><a href="#" id="Bioruptor-Plus-DNA-QC-kit" data-reveal-id="cartModal-2835" class="" style="color:#B21329"><i class="fa fa-cart-plus"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Plus DNA QC kit</h6> </div> </div> </li> <li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/bioruptorpico2"><img src="/img/product/shearing_technologies/B01080000-1.jpg" alt="Bioruptor Pico" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">B01080010</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: QUOTE MODAL --><div id="quoteModal-3046" class="reveal-modal small" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <h3>Get a quote</h3><p class="lead">You are about to request a quote for <strong>Bioruptor<sup>®</sup> Pico sonication device</strong>. Fill out the form below and we will be in touch with you very soon.</p><p><small>All <span style="font-size:16px;color:red;">*</span> fields are mandatory</small></p> </div> </div> <form action="/en/quotes/quote?id=3046" id="Quote-3046" class="quote" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Quote][product_id]" value="3046" id="QuoteProductId"/><input type="hidden" name="data[Quote][formLoaded6tY4bPYk]" value="TnRBbnZnc21IeGdtOURiRm9OVHBWUT09" id="QuoteFormLoaded6tY4bPYk"/><input type="hidden" name="data[Quote][product_rfq_tag]" value="bioruptorpico2" id="QuoteProductRfqTag"/><input type="hidden" name="data[Quote][source_quote]" value="modal quote" id="QuoteSourceQuote"/> <div class="row collapse"> <h2>Contact Information</h2> <div class="small-3 large-2 columns"> <span class="prefix">First name <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 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(SA)</option><option value="SH">Schleswig-Holstein (SH)</option><option value="TH">Thüringen</option></select>'); $("#Quote-3046 #state-3046").parent().parent().show(); } else { $("#Quote-3046 #state-3046").parent().parent().hide(); $("#Quote-3046 #state-3046").replaceWith('<input name="data[Quote][state]" maxlength="255" type="text" id="state-3046" value="">'); } }); </script> <a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: QUOTE MODAL --><a href="#" id="bioruptorpico2" data-reveal-id="quoteModal-3046" class="quote_btn" style="color:#B21329"><i class="fa fa-info-circle"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Pico sonication device</h6> </div> </div> </li> ' $related = array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa 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The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa fa-arrow-circle-right"></i> <a href="https://www.diagenode.com/pages/chromatin-prep-easyshear-kit-guide">Read more</a></h3> </div> <p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> </p> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <script src="chrome-extension://hhojmcideegachlhfgfdhailpfhgknjm/web_accessible_resources/index.js"></script> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'format' => '1 unit', 'catalog_number' => 'B01080010', 'old_catalog_number' => '', 'sf_code' => 'B01080010-', 'type' => 'ACC', 'search_order' => '00-Machine', 'price_EUR' => '27000', 'price_USD' => '30000', 'price_GBP' => '23500', 'price_JPY' => '4229550', 'price_CNY' => '/', 'price_AUD' => '75000', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => true, 'in_stock' => false, 'featured' => true, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => '', 'slug' => 'bioruptorpico2', 'meta_title' => 'Bioruptor® Pico sonication device', 'meta_keywords' => '', 'meta_description' => 'Bioruptor® Pico sonication device', 'modified' => '2024-06-14 15:28:50', 'created' => '2020-01-09 16:27:17', 'ProductsRelated' => array( [maximum depth reached] ), 'Image' => array( [maximum depth reached] ) ) ), 'Application' => array(), 'Category' => array( (int) 0 => array( 'id' => '40', 'position' => '1', 'parent_id' => '6', 'name' => 'Bioruptor<sup>®</sup> Pico accessories', 'description' => '<p>All you need for the smooth running of the Bioruptor<sup>®</sup> Pico. Download our quick guide <a href="../documents/bioruptor-organigram-tubes">"Which tubes for which Bioruptor<sup><span>®</span></sup>?"</a> to find the best tubes for your applications.</p>', 'no_promo' => false, 'in_menu' => false, 'online' => true, 'tabular' => false, 'hide' => false, 'all_format' => false, 'is_antibody' => false, 'slug' => 'bioruptor-pico-accessories', 'cookies_tag_id' => null, 'meta_keywords' => 'Bioruptor® Pico accessories,DNA shearing ,chromatin shearing,sonication device,sonicator', 'meta_description' => 'All you need for the smooth running of the Bioruptor® Pico', 'meta_title' => 'Accessories for Bioruptor® Pico sonication device | Diagenode', 'modified' => '2018-02-14 16:24:24', 'created' => '2015-06-12 10:01:53', 'ProductsCategory' => array( [maximum depth reached] ), 'CookiesTag' => array([maximum depth reached]) ) ), 'Document' => array( (int) 0 => array( 'id' => '917', 'name' => 'Bioruptor® Pico DNA QC kit manual', 'description' => '<p>We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your Bioruptor® and to figure out the right time for servicing. 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However, if your QC pass, we wish you every success with your Bioruptor®.</p>', 'image_id' => null, 'type' => 'Manual', 'url' => 'files/products/kits/DNAQC-kit-Pico-manual.pdf', 'slug' => 'dnaqc-kit-pico-manual', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2016-09-21 17:06:39', 'created' => '2016-09-21 17:06:39', 'ProductsDocument' => array( [maximum depth reached] ) ) ), 'Feature' => array(), 'Image' => array( (int) 0 => array( 'id' => '1746', 'name' => 'product/kits/dnaqckit.jpg', 'alt' => 'dna qc kit', 'modified' => '2016-09-27 17:27:50', 'created' => '2016-09-27 17:27:50', 'ProductsImage' => array( [maximum depth reached] ) ) ), 'Promotion' => array(), 'Protocol' => array(), 'Publication' => array(), 'Testimonial' => array(), 'Area' => array(), 'SafetySheet' => array( (int) 0 => array( 'id' => '742', 'name' => 'DNA QC kit for Bioruptor Pico SDS GB en', 'language' => 'en', 'url' => 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(int) 10 => 'LU', (int) 11 => 'FR', (int) 12 => 'DE', (int) 13 => 'CH', (int) 14 => 'AT', (int) 15 => 'ES', (int) 16 => 'IT', (int) 17 => 'PT' ) $outsource = false $other_formats = array() $edit = '' $testimonials = '' $featured_testimonials = '' $related_products = '<li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/0-5-0-65-ml-tube-holder-for-bioruptor-standard-plus-pico-1-pack"><img src="/img/product/shearing_technologies/B01200043_tube_holder.jpg" alt="Product image" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">B01200043</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: ADD TO CART MODAL --><div id="cartModal-1809" class="reveal-modal small" data-reveal 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</div> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('0.5/0.65 ml tube holder for Bioruptor<sup>®</sup> Standard & Plus', 'B01200043', '1800', $('#CartQuantity').val());" name="keepshop" id="keepshop" type="submit">Keep shopping</button> </div> </div> </div> </div> </form><a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: ADD TO CART MODAL --><a href="#" id="0-5-0-65-ml-tube-holder-for-bioruptor-standard-plus-pico-1-pack" data-reveal-id="cartModal-1809" class="" style="color:#B21329"><i class="fa fa-cart-plus"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">0.5/0.65 ml tube holder for Bioruptor® Stan...</h6> </div> </div> </li> <li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/Bioruptor-Plus-DNA-QC-kit"><img src="/img/product/kits/dnaqckit.jpg" alt="dna qc kit" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">C40010001</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: ADD TO CART MODAL --><div id="cartModal-2835" class="reveal-modal small" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <form action="/en/carts/add/2835" id="CartAdd/2835Form" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Cart][product_id]" value="2835" id="CartProductId"/> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <p>Add <input name="data[Cart][quantity]" placeholder="1" value="1" min="1" style="width:60px;display:inline" type="number" id="CartQuantity" required="required"/> <strong> Bioruptor<sup>®</sup> Plus DNA QC kit</strong> to my shopping cart.</p> <div class="row"> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="checkout" id="checkout" value="checkout" type="submit">Checkout</button> </div> <div class="small-6 medium-6 large-6 columns"> <button class="alert small button expand" onclick="$(this).addToCart('Bioruptor<sup>®</sup> Plus DNA QC kit', 'C40010001', '135', $('#CartQuantity').val());" name="keepshop" id="keepshop" type="submit">Keep shopping</button> </div> </div> </div> </div> </form><a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: ADD TO CART MODAL --><a href="#" id="Bioruptor-Plus-DNA-QC-kit" data-reveal-id="cartModal-2835" class="" style="color:#B21329"><i class="fa fa-cart-plus"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Plus DNA QC kit</h6> </div> </div> </li> <li> <div class="row"> <div class="small-12 columns"> <a href="/en/p/bioruptorpico2"><img src="/img/product/shearing_technologies/B01080000-1.jpg" alt="Bioruptor Pico" class="th"/></a> </div> <div class="small-12 columns"> <div class="small-6 columns" style="padding-left:0px;padding-right:0px;margin-top:-6px;margin-left:-1px"> <span class="success label" style="">B01080010</span> </div> <div class="small-6 columns text-right" style="padding-left:0px;padding-right:0px;margin-top:-6px"> <!--a href="#" style="color:#B21329"><i class="fa fa-info-circle"></i></a--> <!-- BEGIN: QUOTE MODAL --><div id="quoteModal-3046" class="reveal-modal small" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"> <div class="row"> <div class="small-12 medium-12 large-12 columns"> <h3>Get a quote</h3><p class="lead">You are about to request a quote for <strong>Bioruptor<sup>®</sup> Pico sonication device</strong>. Fill out the form below and we will be in touch with you very soon.</p><p><small>All <span style="font-size:16px;color:red;">*</span> fields are mandatory</small></p> </div> </div> <form action="/en/quotes/quote?id=3046" id="Quote-3046" class="quote" method="post" accept-charset="utf-8"><div style="display:none;"><input type="hidden" name="_method" value="POST"/></div><input type="hidden" name="data[Quote][product_id]" value="3046" id="QuoteProductId"/><input type="hidden" name="data[Quote][formLoaded6tY4bPYk]" value="TnRBbnZnc21IeGdtOURiRm9OVHBWUT09" id="QuoteFormLoaded6tY4bPYk"/><input type="hidden" name="data[Quote][product_rfq_tag]" value="bioruptorpico2" id="QuoteProductRfqTag"/><input type="hidden" name="data[Quote][source_quote]" value="modal quote" id="QuoteSourceQuote"/> <div class="row collapse"> <h2>Contact Information</h2> <div class="small-3 large-2 columns"> <span class="prefix">First name <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][first_name]" placeholder="john" maxlength="255" type="text" id="QuoteFirstName" required="required"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Last name <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][last_name]" placeholder="doe" maxlength="255" type="text" id="QuoteLastName" required="required"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Company <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][company]" placeholder="Organisation / Institute" maxlength="255" type="text" id="QuoteCompany" required="required"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Phone number</span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][phone_number]" placeholder="+1 862 209-4680" maxlength="255" type="text" id="QuotePhoneNumber"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">City</span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][city]" placeholder="Denville" maxlength="255" type="text" id="QuoteCity"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Country <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <select name="data[Quote][country]" required="required" class="triggers" id="country_selector_quote-3046"> <option value="">-- select a country --</option> <option value="AF">Afghanistan</option> <option value="AX">Åland Islands</option> <option value="AL">Albania</option> <option value="DZ">Algeria</option> <option value="AS">American Samoa</option> <option value="AD">Andorra</option> <option 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value="CU">Cuba</option> <option value="CW">Curaçao</option> <option value="CY">Cyprus</option> <option value="CZ">Czech Republic</option> <option value="DK">Denmark</option> <option value="DJ">Djibouti</option> <option value="DM">Dominica</option> <option value="DO">Dominican Republic</option> <option value="EC">Ecuador</option> <option value="EG">Egypt</option> <option value="SV">El Salvador</option> <option value="GQ">Equatorial Guinea</option> <option value="ER">Eritrea</option> <option value="EE">Estonia</option> <option value="ET">Ethiopia</option> <option value="FK">Falkland Islands (Malvinas)</option> <option value="FO">Faroe Islands</option> <option value="FJ">Fiji</option> <option value="FI">Finland</option> <option value="FR">France</option> <option value="GF">French Guiana</option> <option value="PF">French Polynesia</option> <option value="TF">French Southern Territories</option> <option value="GA">Gabon</option> <option value="GM">Gambia</option> <option value="GE">Georgia</option> <option value="DE">Germany</option> <option value="GH">Ghana</option> <option value="GI">Gibraltar</option> <option value="GR">Greece</option> <option value="GL">Greenland</option> <option value="GD">Grenada</option> <option value="GP">Guadeloupe</option> <option value="GU">Guam</option> <option value="GT">Guatemala</option> <option value="GG">Guernsey</option> <option value="GN">Guinea</option> <option value="GW">Guinea-Bissau</option> <option value="GY">Guyana</option> <option value="HT">Haiti</option> <option value="HM">Heard Island and McDonald Islands</option> <option value="VA">Holy See (Vatican City State)</option> <option value="HN">Honduras</option> <option value="HK">Hong Kong</option> <option value="HU">Hungary</option> <option value="IS">Iceland</option> <option value="IN">India</option> <option value="ID">Indonesia</option> <option value="IR">Iran, Islamic Republic of</option> <option value="IQ">Iraq</option> <option value="IE">Ireland</option> 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columns"> <input name="data[Quote][state]" id="state-3046" maxlength="3" type="text"/><br /> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Email <sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][email]" placeholder="email@address.com" maxlength="255" type="email" id="QuoteEmail" required="required"/> </div> </div> <div class="row collapse" id="email_v"> <div class="small-3 large-2 columns"> <span class="prefix">Email verification<sup style="font-size:16px;color:red;">*</sup></span> </div> <div class="small-9 large-10 columns"> <input name="data[Quote][email_v]" autocomplete="nope" type="text" id="QuoteEmailV"/> </div> </div> <div class="row collapse"> <div class="small-3 large-2 columns"> <span class="prefix">Comment</span> </div> <div class="small-9 large-10 columns"> <textarea name="data[Quote][comment]" placeholder="Additional comments" cols="30" rows="6" id="QuoteComment"></textarea> </div> </div> <!------------SERVICES PARTICULAR FORM START----------------> <!------------DATA TO POPULATE REGARDING SPECIFIC SERVICES-----> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <div class="recaptcha"><div id="recaptcha67348ec94d228"></div></div> </div> </div> <br /> <div class="row collapse"> <div class="small-3 large-2 columns"> </div> <div class="small-9 large-10 columns"> <button id="submit_btn-3046" class="alert button expand" form="Quote-3046" type="submit">Contact me</button> </div> </div> </form><script> var pardotFormHandlerURL = 'https://go.diagenode.com/l/928883/2022-10-10/36b1c'; function postToPardot(formAction, id) { $('#pardot-form-handler').load(function(){ $('#Quote-' + id).attr('action', formAction); $('#Quote-' + id).submit(); }); $('#pardot-form-handler').attr('src', pardotFormHandlerURL + '?' + $('#Quote-' + id).serialize()); } $(document).ready(function() { 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(SA)</option><option value="SH">Schleswig-Holstein (SH)</option><option value="TH">Thüringen</option></select>'); $("#Quote-3046 #state-3046").parent().parent().show(); } else { $("#Quote-3046 #state-3046").parent().parent().hide(); $("#Quote-3046 #state-3046").replaceWith('<input name="data[Quote][state]" maxlength="255" type="text" id="state-3046" value="">'); } }); </script> <a class="close-reveal-modal" aria-label="Close">×</a></div><!-- END: QUOTE MODAL --><a href="#" id="bioruptorpico2" data-reveal-id="quoteModal-3046" class="quote_btn" style="color:#B21329"><i class="fa fa-info-circle"></i></a> </div> </div> <div class="small-12 columns" > <h6 style="height:60px">Bioruptor® Pico sonication device</h6> </div> </div> </li> ' $related = array( 'id' => '3046', 'antibody_id' => null, 'name' => 'Bioruptor<sup>®</sup> Pico sonication device', 'description' => '<p><a href="https://go.diagenode.com/bioruptor-upgrade"><img src="https://www.diagenode.com/img/banners/banner-br-trade.png" /></a></p> <div class="row"> <div class="small-12 medium-8 large-8 columns"><br /> <p><span>The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. </span>Since 2004, Diagenode has accumulated <strong>shearing expertise</strong> to design the Bioruptor® Pico and guarantee the best experience with the <strong>sample preparation</strong> for <strong>number of applications -- in various fields of studies</strong> including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.</p> </div> <div class="small-12 medium-4 large-4 columns"><center> <script>// <![CDATA[ var date = new Date(); var heure = date.getHours(); var jour = date.getDay(); var semaine = Math.floor(date.getDate() / 7) + 1; if (jour === 2 && ( (heure >= 9 && heure < 9.5) || (heure >= 18 && heure < 18.5) )) { document.write('<a href="https://us02web.zoom.us/j/85467619762"><img src="https://www.diagenode.com/img/epicafe-ON.gif"></a>'); } else { document.write('<a href="https://go.diagenode.com/l/928883/2023-04-26/3kq1v"><img src="https://www.diagenode.com/img/epicafe-OFF.png"></a>'); } // ]]></script> </center></div> </div> <p>The Bioruptor Pico shearing accessories and consumables have been developed to allow <strong>flexibility in sample volumes</strong> (20 µl - 2 ml) and a <strong>fast parallel processing of samples</strong> (up to 16 samples simultaneously). <span>The built-in cooling system (Bioruptor® Cooler) ensures high precision <strong>temperature control</strong>. The <strong>user-friendly interface</strong> has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control. </span></p> <p>In addition, Diagenode provides fully-validated tubes that remain <strong>budget-friendly with low operating cost</strong> (< 1€/$/DNA sample) and shearing kits for best sample quality. <span></span></p> <p><strong>Application versatility</strong>:</p> <ul> <li>DNA shearing for Next-Generation-Sequencing</li> <li>Chromatin shearing</li> <li>RNA shearing</li> <li>Protein extraction from tissues and cells (also for mass spectrometry)</li> <li>FFPE DNA extraction</li> <li>Protein aggregation studies</li> <li>CUT&RUN - shearing of input DNA for NGS</li> </ul> <div style="background-color: #f1f3f4; margin: 10px; padding: 50px;"> <p><strong>Bioruptor Pico: Recommended for CUT&RUN sequencing for input DNA</strong><br /><br /> By combining antibody-targeted controlled cleavage by MNase and NGS, <strong>CUT&RUN sequencing</strong> can be used to identify protein-DNA binding sites genome-wide. CUT&RUN works by using the DNA cleaving activity of a Protein A-fused MNase to isolate DNA that is bound by a protein of interest. This targeted digestion is controlled by the addition of calcium, which MNase requires for its nuclease activity. After MNase digestion, short DNA fragments are released and can then be purified for subsequent library preparation and high-throughput sequencing. While CUT&RUN does not require mechanical shearing chromatin given the enzymatic approach, sonication is highly recommended for the fragmentation of the input DNA (used to compare the enriched sample) in order to be compatible with downstream NGS. The Bioruptor Pico is the ideal instrument of choice for generating optimal DNA fragments with a tight distribution, assuring excellent library prep and excellent sequencing results for your CUT&RUN assay.<br /><br /> <strong>Explore the Bioruptor Pico now.</strong></p> </div> <div class="extra-spaced"><center><img alt="Bioruptor Sonication for Chromatin shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-reproducibility-is-priority.jpg" /></center></div> <div class="extra-spaced"><center><a href="https://www.diagenode.com/en/pages/form-demo"> <img alt="Bioruptor Sonication for RNA shearing" src="https://www.diagenode.com/img/product/shearing_technologies/pico-request-demo.jpg" /></a></center></div> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label1' => 'Specifications', 'info1' => '<center><img alt="Ultrasonic Sonicator" src="https://www.diagenode.com/img/product/shearing_technologies/pico-table.jpg" /></center> <div id="ConnectiveDocSignExtentionInstalled" data-extension-version="1.0.4"></div>', 'label2' => 'View accessories & consumables for Bioruptor<sup>®</sup> Pico', 'info2' => '<h3>Shearing Accessories</h3> <table style="width: 641px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 300px; height: 37px;"><strong>Name</strong></td> <td style="width: 171px; text-align: center; height: 37px;">Catalog number</td> <td style="width: 160px; text-align: center; height: 37px;">Throughput</td> </tr> </thead> <tbody> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-2-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.2 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201144</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">16 samples</span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/0-65-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 0.65 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201143</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">12 samples<br /></span></td> </tr> <tr style="height: 38px;"> <td style="width: 300px; height: 38px;"><a href="https://www.diagenode.com/en/p/1-5-ml-tube-holder-dock-for-bioruptor-pico">Tube holder for 1.5 ml tubes</a></td> <td style="width: 171px; text-align: center; height: 38px;"><span style="font-weight: 400;">B01201140</span></td> <td style="width: 160px; text-align: center; height: 38px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> <tr style="height: 37px;"> <td style="width: 300px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-sonication-accessories-for-bioruptor-standard-plus-pico-1-pack">15 ml sonication accessories</a></td> <td style="width: 171px; text-align: center; height: 37px;"><span style="font-weight: 400;">B01200016</span></td> <td style="width: 160px; text-align: center; height: 37px;"><span style="font-weight: 400;">6 samples<br /></span></td> </tr> </tbody> </table> <h3>Shearing Consumables</h3> <table style="width: 646px;"> <thead> <tr style="background-color: #dddddd; height: 37px;"> <td style="width: 286px; height: 37px;"><strong>Name</strong></td> <td style="width: 76px; height: 37px; text-align: center;">Catalog Number</td> </tr> </thead> <tbody> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/02ml-microtubes-for-bioruptor-pico">0.2 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010020</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/0-65-ml-bioruptor-microtubes-500-tubes">0.65 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010011</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/1-5-ml-bioruptor-microtubes-with-caps-300-tubes">1.5 ml Pico Microtubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010016</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-50-pc">15 ml Pico Tubes</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C30010017</span></td> </tr> <tr style="height: 37px;"> <td style="width: 286px; height: 37px;"><a href="https://www.diagenode.com/en/p/15-ml-bioruptor-tubes-sonication-beads-50-rxns">15 ml Pico Tubes & sonication beads</a></td> <td style="width: 76px; height: 37px; text-align: center;"><span style="font-weight: 400;">C01020031</span></td> </tr> </tbody> </table> <p><a href="https://www.diagenode.com/files/products/shearing_technology/bioruptor_accessories/TDS-BioruptorTubes.pdf">Find datasheet for Diagenode tubes here</a></p> <p><a href="../documents/bioruptor-organigram-tubes">Which tubes for which Bioruptor®?</a></p>', 'label3' => 'Available shearing Kits', 'info3' => '<p>Diagenode has optimized a range of solutions for <strong>successful chromatin preparation</strong>. Chromatin EasyShear Kits together with the Pico ultrasonicator combine the benefits of efficient cell lysis and chromatin shearing, while keeping epitopes accessible to the antibody, critical for efficient chromatin immunoprecipitation. Each Chromatin EasyShear Kit provides optimized reagents and a thoroughly validated protocol according to your specific experimental needs. SDS concentration is adapted to each workflow taking into account target-specific requirements.</p> <p>For best results, choose your desired ChIP kit followed by the corresponding Chromatin EasyShear Kit (to optimize chromatin shearing ). The Chromatin EasyShear Kits can be used independently of Diagenode’s ChIP kits for chromatin preparation prior to any chromatin immunoprecipitation protocol. Choose an appropriate kit for your specific experimental needs.</p> <h2>Kit choice guide</h2> <table style="border: 0;" valign="center"> <tbody> <tr style="background: #fff;"> <th class="text-center"></th> <th class="text-center" style="font-size: 17px;">SAMPLE TYPE</th> <th class="text-center" style="font-size: 17px;">SAMPLE INPUT</th> <th class="text-center" style="font-size: 17px;">KIT</th> <th class="text-center" style="font-size: 17px;">SDS<br /> CONCENTRATION</th> <th class="text-center" style="font-size: 17px;">NUCLEI<br /> ISOLATION</th> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="5"><img src="https://www.diagenode.com/img/label-histones.png" /></td> <td class="text-center" style="border-bottom: 1px solid #dedede;"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">< 100,000</td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-optimization-kit-high-sds-100-million-cells">Chromatin EasyShear Kit<br />High SDS</a></td> <td class="text-center" style="font-size: 17px; border-bottom: 1px solid #dedede;">1%</td> <td class="text-center" style="border-bottom: 1px solid #dedede;"><img src="https://www.diagenode.com/img/cross-unvalid-green.jpg" width="18" height="20" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center" style="font-size: 17px;">> 100,000</td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-ultra-low-sds">Chromatin EasyShear Kit<br />Ultra Low SDS</a></td> <td class="text-center" style="font-size: 17px;">< 0.1%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff; border-bottom: 1px solid #dedede;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">PLANT TISSUE</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-shearing-plant-chip-seq-kit">Chromatin EasyShear Kit<br />for Plant</a></td> <td class="text-center" style="font-size: 17px;">0.5%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> <td class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td class="text-center" style="font-size: 17px;">0.2%</td> <td class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td colspan="7"></td> </tr> <tr style="background: #fff;"> <td rowspan="6"><img src="https://www.diagenode.com/img/label-tf.png" /></td> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">CELLS</div> </td> <td class="text-center"></td> <td rowspan="3" class="text-center" style="font-size: 17px;"><a href="https://www.diagenode.com/en/p/chromatin-easyshear-kit-low-sds">Chromatin EasyShear Kit<br />Low SDS</a></td> <td rowspan="3" class="text-center" style="font-size: 17px;">0.2%</td> <td rowspan="3" class="text-center"><img src="https://www.diagenode.com/img/valid.png" width="20" height="16" /></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">TISSUE</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td class="text-center"> <div class="label alert" style="font-size: 17px;">FFPE SAMPLES</div> </td> <td class="text-center"></td> </tr> <tr style="background: #fff;"> <td colspan="6"></td> </tr> </tbody> </table> <div class="extra-spaced"> <h3>Guide for optimal chromatin preparation using Chromatin EasyShear Kits <i class="fa 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reached] ) ) ) ) $rrbs_service = array( (int) 0 => (int) 1894, (int) 1 => (int) 1895 ) $chipseq_service = array( (int) 0 => (int) 2683, (int) 1 => (int) 1835, (int) 2 => (int) 1836, (int) 3 => (int) 2684, (int) 4 => (int) 1838, (int) 5 => (int) 1839, (int) 6 => (int) 1856 ) $labelize = object(Closure) { } $old_catalog_number = '' $country_code = 'US' $label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>' $document = array( 'id' => '917', 'name' => 'Bioruptor® Pico DNA QC kit manual', 'description' => '<p>We have developed the DNA Quality Control Kit for you to be able to track the efficiency of your Bioruptor® and to figure out the right time for servicing. After the sonication, if your QC does not reach our standards, please, contact Diagenode for recommendations. However, if your QC pass, we wish you every success with your Bioruptor®.</p>', 'image_id' => null, 'type' => 'Manual', 'url' => 'files/products/kits/DNAQC-kit-Pico-manual.pdf', 'slug' => 'dnaqc-kit-pico-manual', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2016-09-21 17:06:39', 'created' => '2016-09-21 17:06:39', 'ProductsDocument' => array( 'id' => '2208', 'product_id' => '2837', 'document_id' => '917' ) ) $sds = array( 'id' => '740', 'name' => 'DNA QC kit for Bioruptor Pico SDS ES es', 'language' => 'es', 'url' => 'files/SDS/Bioruptor_Pico/SDS-C40010002-DNA_QC_kit_for_Bioruptor_Pico-ES-es-GHS_1_0.pdf', 'countries' => 'ES', 'modified' => '2020-09-18 15:46:38', 'created' => '2020-09-18 15:46:38', 'ProductsSafetySheet' => array( 'id' => '1363', 'product_id' => '2837', 'safety_sheet_id' => '740' ) )include - APP/View/Products/view.ctp, line 755 View::_evaluate() - CORE/Cake/View/View.php, line 971 View::_render() - CORE/Cake/View/View.php, line 933 View::render() - CORE/Cake/View/View.php, line 473 Controller::render() - CORE/Cake/Controller/Controller.php, line 963 ProductsController::slug() - APP/Controller/ProductsController.php, line 1052 ReflectionMethod::invokeArgs() - [internal], line ?? Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491 Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193 Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167 [main] - APP/webroot/index.php, line 118
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