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Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.
| Lot | 002 |
|---|---|
| Concentration | 2 µg/µl |
| Species reactivity | Human, other (wide range): positive. |
| Type | Monoclonal |
| Purity | Protein A purified monoclonal antibody. |
| Host | Mouse |
| Storage Conditions | Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.05% sodium azide. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Applications | Suggested dilution | References |
|---|---|---|
| RIP * | 1 µg per IP | Fig 1 |
*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.
Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine
IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control.
Figure 1A The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody.
Figure 1B shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.
| Epigenetic Antibodies Brochure BROCHURE More than in any other immuoprecipitation assays, quality antibodies are critical tools in many e... | Download |
| Datasheet Inosine Antibody C15200251 DATASHEET | Download |
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Notice (8): Undefined variable: solution_of_interest [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL --><div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"><?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>$viewFile = '/home/website-server/www/app/View/Products/view.ctp' $dataForView = array( 'language' => 'en', 'meta_keywords' => '', 'meta_description' => '', 'meta_title' => '', 'product' => array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. 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We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( [maximum depth reached] ) ), 'Group' => array( 'Group' => array( [maximum depth reached] ), 'Master' => array( [maximum depth reached] ), 'Product' => array( [maximum depth reached] ) ), 'Related' => array(), 'Application' => array( (int) 0 => array( [maximum depth reached] ) ), 'Category' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Document' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Feature' => array(), 'Image' => array( (int) 0 => array( [maximum depth reached] ) ), 'Promotion' => array(), 'Protocol' => array(), 'Publication' => array(), 'Testimonial' => array(), 'Area' => array(), 'SafetySheet' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ), (int) 2 => array( [maximum depth reached] ), (int) 3 => array( [maximum depth reached] ), (int) 4 => array( [maximum depth reached] ), (int) 5 => array( [maximum depth reached] ), (int) 6 => array( [maximum depth reached] ), (int) 7 => array( [maximum depth reached] ) ) ), 'meta_canonical' => 'https://www.diagenode.com/en/p/inosine-monoclonal-antibody-50' ) $language = 'en' $meta_keywords = '' $meta_description = '' $meta_title = '' $product = array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. 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We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ) ), 'Group' => array( 'Group' => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ), 'Master' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). 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Check out all of our highly sensitive and specific antibodies for RNA modifications studies below.</span></p> <p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p> <ul> <li>Highly sensitive and specific</li> <li>Cost-effective (requires less antibody per reaction)</li> <li>Batch-specific data is available on the website</li> <li>Expert technical support</li> <li>Sample sizes available</li> <li>100% satisfaction guarantee</li> </ul> </div> </div>', 'no_promo' => false, 'in_menu' => true, 'online' => true, 'tabular' => false, 'hide' => true, 'all_format' => false, 'is_antibody' => true, 'slug' => 'rna-modifications-antibodies', 'cookies_tag_id' => null, 'meta_keywords' => 'm6A polyclonal antibody ,Monoclonal antibody', 'meta_description' => 'Diagenode offers a wide range of RNA modifications antibodies', 'meta_title' => 'RNA modifications antibodies | Diagenode.com', 'modified' => '2020-09-01 11:43:28', 'created' => '2016-02-15 10:58:08', 'ProductsCategory' => array( [maximum depth reached] ), 'CookiesTag' => array([maximum depth reached]) ), (int) 1 => array( 'id' => '103', 'position' => '0', 'parent_id' => '4', 'name' => 'All antibodies', 'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. 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Notice (8): Undefined variable: header [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL --><div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"><?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>$viewFile = '/home/website-server/www/app/View/Products/view.ctp' $dataForView = array( 'language' => 'en', 'meta_keywords' => '', 'meta_description' => '', 'meta_title' => '', 'product' => array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. It is an essential modification introduced by specialized enzymes in a highly regulated manner to generate transcriptome diversity and deficiencies of the enzymes involved in this conversion leads to a variety in diseases including cancer, viral infections and neurological and psychiatric disorders. Only a small part of the Inosine conversions occurs in coding sequences; the vast majority is present in noncoding sequences such as microRNAs, tRNAs, and introns and 3′ untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression.', 'clonality' => '', 'isotype' => ' IgG1', 'lot' => '002', 'concentration' => '2 µg/µl', 'reactivity' => 'Human, other (wide range): positive.', 'type' => 'Monoclonal', 'purity' => 'Protein A purified monoclonal antibody.', 'classification' => '', 'application_table' => '<table> <thead> <tr> <th>Applications</th> <th>Suggested dilution</th> <th>References</th> </tr> </thead> <tbody> <tr> <td>RIP <sup>*</sup></td> <td>1 µg per IP</td> <td>Fig 1</td> </tr> </tbody> </table> <p></p> <p><small>*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( [maximum depth reached] ) ), 'Group' => array( 'Group' => array( [maximum depth reached] ), 'Master' => array( [maximum depth reached] ), 'Product' => array( [maximum depth reached] ) ), 'Related' => array(), 'Application' => array( (int) 0 => array( [maximum depth reached] ) ), 'Category' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Document' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Feature' => array(), 'Image' => array( (int) 0 => array( [maximum depth reached] ) ), 'Promotion' => array(), 'Protocol' => array(), 'Publication' => array(), 'Testimonial' => array(), 'Area' => array(), 'SafetySheet' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ), (int) 2 => array( [maximum depth reached] ), (int) 3 => array( [maximum depth reached] ), (int) 4 => array( [maximum depth reached] ), (int) 5 => array( [maximum depth reached] ), (int) 6 => array( [maximum depth reached] ), (int) 7 => array( [maximum depth reached] ) ) ), 'meta_canonical' => 'https://www.diagenode.com/en/p/inosine-monoclonal-antibody-50' ) $language = 'en' $meta_keywords = '' $meta_description = '' $meta_title = '' $product = array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. It is an essential modification introduced by specialized enzymes in a highly regulated manner to generate transcriptome diversity and deficiencies of the enzymes involved in this conversion leads to a variety in diseases including cancer, viral infections and neurological and psychiatric disorders. Only a small part of the Inosine conversions occurs in coding sequences; the vast majority is present in noncoding sequences such as microRNAs, tRNAs, and introns and 3′ untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression.', 'clonality' => '', 'isotype' => ' IgG1', 'lot' => '002', 'concentration' => '2 µg/µl', 'reactivity' => 'Human, other (wide range): positive.', 'type' => 'Monoclonal', 'purity' => 'Protein A purified monoclonal antibody.', 'classification' => '', 'application_table' => '<table> <thead> <tr> <th>Applications</th> <th>Suggested dilution</th> <th>References</th> </tr> </thead> <tbody> <tr> <td>RIP <sup>*</sup></td> <td>1 µg per IP</td> <td>Fig 1</td> </tr> </tbody> </table> <p></p> <p><small>*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ) ), 'Group' => array( 'Group' => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ), 'Master' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18' ), 'Product' => array( (int) 0 => array( [maximum depth reached] ) ) ), 'Related' => array(), 'Application' => array( (int) 0 => array( 'id' => '36', 'position' => '10', 'parent_id' => '40', 'name' => 'RIP', 'description' => '<p>RIP</p>', 'in_footer' => false, 'in_menu' => false, 'online' => true, 'tabular' => true, 'slug' => 'rip', 'meta_keywords' => 'RIP antibodies,classic monoclonal antibodies,Ago (Argonautes) monoclonal antibody,Snf2h monoclonal antibody - Classic,Diagenode', 'meta_description' => 'Diagenode offers a wide range of classic monoclonal RIP antibodies.', 'meta_title' => 'RIP antibodies | Diagenode', 'modified' => '2016-01-21 08:09:31', 'created' => '2015-07-08 13:54:45', 'ProductsApplication' => array( [maximum depth reached] ) ) ), 'Category' => array( (int) 0 => array( 'id' => '109', 'position' => '40', 'parent_id' => '4', 'name' => 'RNA modifications', 'description' => '<div class="row"> <div style="text-align: justify;" class="large-12 columns"> <p><span style="font-weight: 400;">Diagenode’s large range of highly validated antibodies includes the antibodies to study RNA modifications. These antibodies have been thoroughly validated for many applications (RIP, WB, IF, ELISA, Dot blot, IP). Check out all of our highly sensitive and specific antibodies for RNA modifications studies below.</span></p> <p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p> <ul> <li>Highly sensitive and specific</li> <li>Cost-effective (requires less antibody per reaction)</li> <li>Batch-specific data is available on the website</li> <li>Expert technical support</li> <li>Sample sizes available</li> <li>100% satisfaction guarantee</li> </ul> </div> </div>', 'no_promo' => false, 'in_menu' => true, 'online' => true, 'tabular' => false, 'hide' => true, 'all_format' => false, 'is_antibody' => true, 'slug' => 'rna-modifications-antibodies', 'cookies_tag_id' => null, 'meta_keywords' => 'm6A polyclonal antibody ,Monoclonal antibody', 'meta_description' => 'Diagenode offers a wide range of RNA modifications antibodies', 'meta_title' => 'RNA modifications antibodies | Diagenode.com', 'modified' => '2020-09-01 11:43:28', 'created' => '2016-02-15 10:58:08', 'ProductsCategory' => array( [maximum depth reached] ), 'CookiesTag' => array([maximum depth reached]) ), (int) 1 => array( 'id' => '103', 'position' => '0', 'parent_id' => '4', 'name' => 'All antibodies', 'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. 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Notice (8): Undefined variable: message [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL --><div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"><?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>$viewFile = '/home/website-server/www/app/View/Products/view.ctp' $dataForView = array( 'language' => 'en', 'meta_keywords' => '', 'meta_description' => '', 'meta_title' => '', 'product' => array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. It is an essential modification introduced by specialized enzymes in a highly regulated manner to generate transcriptome diversity and deficiencies of the enzymes involved in this conversion leads to a variety in diseases including cancer, viral infections and neurological and psychiatric disorders. Only a small part of the Inosine conversions occurs in coding sequences; the vast majority is present in noncoding sequences such as microRNAs, tRNAs, and introns and 3′ untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression.', 'clonality' => '', 'isotype' => ' IgG1', 'lot' => '002', 'concentration' => '2 µg/µl', 'reactivity' => 'Human, other (wide range): positive.', 'type' => 'Monoclonal', 'purity' => 'Protein A purified monoclonal antibody.', 'classification' => '', 'application_table' => '<table> <thead> <tr> <th>Applications</th> <th>Suggested dilution</th> <th>References</th> </tr> </thead> <tbody> <tr> <td>RIP <sup>*</sup></td> <td>1 µg per IP</td> <td>Fig 1</td> </tr> </tbody> </table> <p></p> <p><small>*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( [maximum depth reached] ) ), 'Group' => array( 'Group' => array( [maximum depth reached] ), 'Master' => array( [maximum depth reached] ), 'Product' => array( [maximum depth reached] ) ), 'Related' => array(), 'Application' => array( (int) 0 => array( [maximum depth reached] ) ), 'Category' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Document' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Feature' => array(), 'Image' => array( (int) 0 => array( [maximum depth reached] ) ), 'Promotion' => array(), 'Protocol' => array(), 'Publication' => array(), 'Testimonial' => array(), 'Area' => array(), 'SafetySheet' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ), (int) 2 => array( [maximum depth reached] ), (int) 3 => array( [maximum depth reached] ), (int) 4 => array( [maximum depth reached] ), (int) 5 => array( [maximum depth reached] ), (int) 6 => array( [maximum depth reached] ), (int) 7 => array( [maximum depth reached] ) ) ), 'meta_canonical' => 'https://www.diagenode.com/en/p/inosine-monoclonal-antibody-50' ) $language = 'en' $meta_keywords = '' $meta_description = '' $meta_title = '' $product = array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. 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We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. 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RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). 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These antibodies have been thoroughly validated for many applications (RIP, WB, IF, ELISA, Dot blot, IP). Check out all of our highly sensitive and specific antibodies for RNA modifications studies below.</span></p> <p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p> <ul> <li>Highly sensitive and specific</li> <li>Cost-effective (requires less antibody per reaction)</li> <li>Batch-specific data is available on the website</li> <li>Expert technical support</li> <li>Sample sizes available</li> <li>100% satisfaction guarantee</li> </ul> </div> </div>', 'no_promo' => false, 'in_menu' => true, 'online' => true, 'tabular' => false, 'hide' => true, 'all_format' => false, 'is_antibody' => true, 'slug' => 'rna-modifications-antibodies', 'cookies_tag_id' => null, 'meta_keywords' => 'm6A polyclonal antibody ,Monoclonal antibody', 'meta_description' => 'Diagenode offers a wide range of RNA modifications antibodies', 'meta_title' => 'RNA modifications antibodies | Diagenode.com', 'modified' => '2020-09-01 11:43:28', 'created' => '2016-02-15 10:58:08', 'ProductsCategory' => array( [maximum depth reached] ), 'CookiesTag' => array([maximum depth reached]) ), (int) 1 => array( 'id' => '103', 'position' => '0', 'parent_id' => '4', 'name' => 'All antibodies', 'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. Please, use our Quick search field to find the antibody of interest by target name, application, purity.</span></p> <p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p> <ul> <li>Highly sensitive and specific</li> <li>Cost-effective (requires less antibody per reaction)</li> <li>Batch-specific data is available on the website</li> <li>Expert technical support</li> <li>Sample sizes available</li> <li>100% satisfaction guarantee</li> </ul>', 'no_promo' => false, 'in_menu' => true, 'online' => true, 'tabular' => false, 'hide' => true, 'all_format' => false, 'is_antibody' => true, 'slug' => 'all-antibodies', 'cookies_tag_id' => null, 'meta_keywords' => 'Antibodies,Premium Antibodies,Classic,Pioneer', 'meta_description' => 'Diagenode Offers Strict quality standards with Rigorous QC and validated Antibodies. Classified based on level of validation for flexibility of Application. 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'', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '10 µg', 'catalog_number' => 'C15200251-10', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000582', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '105', 'price_USD' => '115', 'price_GBP' => '100', 'price_JPY' => '16450', 'price_CNY' => '', 'price_AUD' => '288', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => false, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-10', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2021-05-20 11:21:45', 'created' => '2020-12-10 17:28:29', 'ProductsGroup' => array( 'id' => '374', 'product_id' => '3167', 'group_id' => '333' ) ) $img = 'banners/banner-cut_tag-chipmentation-500.jpg' $label = '<img src="/img/banners/banner-customizer-back.png" alt=""/>' $application = array( 'id' => '36', 'position' => '10', 'parent_id' => '40', 'name' => 'RIP', 'description' => '<p>RIP</p>', 'in_footer' => false, 'in_menu' => false, 'online' => true, 'tabular' => true, 'slug' => 'rip', 'meta_keywords' => 'RIP antibodies,classic monoclonal antibodies,Ago (Argonautes) monoclonal antibody,Snf2h monoclonal antibody - Classic,Diagenode', 'meta_description' => 'Diagenode offers a wide range of classic monoclonal RIP antibodies.', 'meta_title' => 'RIP antibodies | Diagenode', 'modified' => '2016-01-21 08:09:31', 'created' => '2015-07-08 13:54:45', 'ProductsApplication' => array( 'id' => '5384', 'product_id' => '3166', 'application_id' => '36' ) ) $slugs = array( (int) 0 => 'rip' ) $applications = array( 'id' => '36', 'position' => '10', 'parent_id' => '40', 'name' => 'RIP', 'description' => '<p>RIP</p>', 'in_footer' => false, 'in_menu' => false, 'online' => true, 'tabular' => true, 'slug' => 'rip', 'meta_keywords' => 'RIP antibodies,classic monoclonal antibodies,Ago (Argonautes) monoclonal antibody,Snf2h monoclonal antibody - Classic,Diagenode', 'meta_description' => 'Diagenode offers a wide range of classic monoclonal RIP antibodies.', 'meta_title' => 'RIP antibodies | Diagenode', 'modified' => '2016-01-21 08:09:31', 'created' => '2015-07-08 13:54:45', 'locale' => 'eng' ) $description = '<p>RIP</p>' $name = 'RIP' $document = array( 'id' => '1117', 'name' => 'Datasheet Inosine Antibody C15200251', 'description' => '', 'image_id' => null, 'type' => 'Datasheet', 'url' => 'files/products/antibodies/Datasheet_inosine_C15200251.pdf', 'slug' => 'inosine-monoclonal-antibody-datasheet', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2020-12-11 09:47:05', 'created' => '2020-12-10 17:34:39', 'ProductsDocument' => array( 'id' => '3061', 'product_id' => '3166', 'document_id' => '1117' ) ) $sds = array( 'id' => '970', 'name' => 'Inosine Antibody SDS BE nl', 'language' => 'nl', 'url' => 'files/SDS/Inosine/SDS-C15200251-Inosine_Antibody-BE-nl-GHS_1_0.pdf', 'countries' => 'BE', 'modified' => '2021-01-12 16:38:24', 'created' => '2021-01-12 16:38:24', 'ProductsSafetySheet' => array( 'id' => '1698', 'product_id' => '3166', 'safety_sheet_id' => '970' ) )include - APP/View/Products/view.ctp, line 755 View::_evaluate() - CORE/Cake/View/View.php, line 971 View::_render() - CORE/Cake/View/View.php, line 933 View::render() - CORE/Cake/View/View.php, line 473 Controller::render() - CORE/Cake/Controller/Controller.php, line 963 ProductsController::slug() - APP/Controller/ProductsController.php, line 1052 ReflectionMethod::invokeArgs() - [internal], line ?? Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491 Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193 Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167 [main] - APP/webroot/index.php, line 118
Notice (8): Undefined variable: campaign_id [APP/View/Products/view.ctp, line 755]Code Context<!-- BEGIN: REQUEST_FORM MODAL --><div id="request_formModal" class="reveal-modal medium" data-reveal aria-labelledby="modalTitle" aria-hidden="true" role="dialog"><?= $this->element('Forms/simple_form', array('solution_of_interest' => $solution_of_interest, 'header' => $header, 'message' => $message, 'campaign_id' => $campaign_id)) ?>$viewFile = '/home/website-server/www/app/View/Products/view.ctp' $dataForView = array( 'language' => 'en', 'meta_keywords' => '', 'meta_description' => '', 'meta_title' => '', 'product' => array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. It is an essential modification introduced by specialized enzymes in a highly regulated manner to generate transcriptome diversity and deficiencies of the enzymes involved in this conversion leads to a variety in diseases including cancer, viral infections and neurological and psychiatric disorders. Only a small part of the Inosine conversions occurs in coding sequences; the vast majority is present in noncoding sequences such as microRNAs, tRNAs, and introns and 3′ untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression.', 'clonality' => '', 'isotype' => ' IgG1', 'lot' => '002', 'concentration' => '2 µg/µl', 'reactivity' => 'Human, other (wide range): positive.', 'type' => 'Monoclonal', 'purity' => 'Protein A purified monoclonal antibody.', 'classification' => '', 'application_table' => '<table> <thead> <tr> <th>Applications</th> <th>Suggested dilution</th> <th>References</th> </tr> </thead> <tbody> <tr> <td>RIP <sup>*</sup></td> <td>1 µg per IP</td> <td>Fig 1</td> </tr> </tbody> </table> <p></p> <p><small>*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( [maximum depth reached] ) ), 'Group' => array( 'Group' => array( [maximum depth reached] ), 'Master' => array( [maximum depth reached] ), 'Product' => array( [maximum depth reached] ) ), 'Related' => array(), 'Application' => array( (int) 0 => array( [maximum depth reached] ) ), 'Category' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Document' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ), 'Feature' => array(), 'Image' => array( (int) 0 => array( [maximum depth reached] ) ), 'Promotion' => array(), 'Protocol' => array(), 'Publication' => array(), 'Testimonial' => array(), 'Area' => array(), 'SafetySheet' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ), (int) 2 => array( [maximum depth reached] ), (int) 3 => array( [maximum depth reached] ), (int) 4 => array( [maximum depth reached] ), (int) 5 => array( [maximum depth reached] ), (int) 6 => array( [maximum depth reached] ), (int) 7 => array( [maximum depth reached] ) ) ), 'meta_canonical' => 'https://www.diagenode.com/en/p/inosine-monoclonal-antibody-50' ) $language = 'en' $meta_keywords = '' $meta_description = '' $meta_title = '' $product = array( 'Product' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). The marker (in bp) is shown on the left, the position of the 28s and 18s ribosomal RNA and of both spike in controls is indicated on the right.</p> </div> </div> <p></p> <p></p>', 'label2' => '', 'info2' => '', 'label3' => '', 'info3' => '', 'format' => '50 µg/29 µl', 'catalog_number' => 'C15200251', 'old_catalog_number' => '', 'sf_code' => 'C15200251-D001-000581', 'type' => 'FRE', 'search_order' => '03-Antibody', 'price_EUR' => '380', 'price_USD' => '380', 'price_GBP' => '340', 'price_JPY' => '59525', 'price_CNY' => '', 'price_AUD' => '950', 'country' => 'ALL', 'except_countries' => 'None', 'quote' => false, 'in_stock' => false, 'featured' => false, 'no_promo' => false, 'online' => true, 'master' => true, 'last_datasheet_update' => 'November 16, 2020', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_title' => '', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2024-02-02 09:56:13', 'created' => '2020-12-09 10:59:18', 'locale' => 'eng' ), 'Antibody' => array( 'host' => '*****', 'id' => '628', 'name' => 'Inosine monoclonal antibody', 'description' => 'The formation of Inosine by deamination of adenosine is probably one of the most common post-translational modifications in RNA. It is an essential modification introduced by specialized enzymes in a highly regulated manner to generate transcriptome diversity and deficiencies of the enzymes involved in this conversion leads to a variety in diseases including cancer, viral infections and neurological and psychiatric disorders. Only a small part of the Inosine conversions occurs in coding sequences; the vast majority is present in noncoding sequences such as microRNAs, tRNAs, and introns and 3′ untranslated regions of messenger RNAs, which play important roles in the RNA-mediated regulation of gene expression.', 'clonality' => '', 'isotype' => ' IgG1', 'lot' => '002', 'concentration' => '2 µg/µl', 'reactivity' => 'Human, other (wide range): positive.', 'type' => 'Monoclonal', 'purity' => 'Protein A purified monoclonal antibody.', 'classification' => '', 'application_table' => '<table> <thead> <tr> <th>Applications</th> <th>Suggested dilution</th> <th>References</th> </tr> </thead> <tbody> <tr> <td>RIP <sup>*</sup></td> <td>1 µg per IP</td> <td>Fig 1</td> </tr> </tbody> </table> <p></p> <p><small>*Please note that the optimal antibody amount per IP should be determined by the end-user. We recommend testing 1 - 10 µg per IP.</small></p>', 'storage_conditions' => 'Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.', 'storage_buffer' => 'PBS containing 0.05% sodium azide.', 'precautions' => 'This product is for research use only. Not for use in diagnostic or therapeutic procedures.', 'uniprot_acc' => '', 'slug' => 'inosine-monoclonal-antibody-50', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2023-02-09 15:22:52', 'created' => '2020-12-09 10:56:28', 'select_label' => '628 - Inosine monoclonal antibody (002 - 2 µg/µl - Human, other (wide range): positive. - Protein A purified monoclonal antibody. - Mouse)' ), 'Slave' => array( (int) 0 => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ) ), 'Group' => array( 'Group' => array( 'id' => '333', 'name' => 'C15200251', 'product_id' => '3166', 'modified' => '2020-12-10 17:29:05', 'created' => '2020-12-10 17:29:05' ), 'Master' => array( 'id' => '3166', 'antibody_id' => '628', 'name' => 'Inosine Antibody', 'description' => '<p>Monoclonal antibody raised in mouse using Inosine (I) conjugated to BSA as immunogen.</p>', 'label1' => 'Validation Data', 'info1' => '<div class="row"> <div class="small-12 columns">A.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1a-rip.png" width="650" /></center></div> </div> <div class="row"> <div class="small-12 columns">B.<center><img src="https://www.diagenode.com/img/product/antibodies/c15200251-fig1b-rip.png" width="500" /></center></div> <div class="small-12 columns"> <p><strong></strong></p> <p><strong>Figure 1. RNA immunoprecipitation using the Diagenode monoclonal antibody directed against Inosine</strong><br />IP was performed with the Diagenode antibody against Inosine (cat. No. C15200251) on 40 µg total RNA from human HeLa cells, spiked with an in vitro produced RNA molecule containing Inosine nucleotides as well as an unmodified control RNA (40 ng each). A titration of the antibody of 1, 2 and 5 µg was analyzed. IgG (2 µg/IP) was used as negative control. <br /><strong>Figure 1A</strong> The immunoprecipitated RNA was subsequently analysed on a Bioanalyzer. The peak at ~500 bp corresponds to the Inosine spike in, whereas the negative control spike in (expected size ~300 bp) is not captured by the antibody. <br /><strong>Figure 1B</strong> shows the gel image for the Inosine antibody (lane 1, 2 and 3), the IgG negative control (lane 4) and the input (lane 5). 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These antibodies have been thoroughly validated for many applications (RIP, WB, IF, ELISA, Dot blot, IP). Check out all of our highly sensitive and specific antibodies for RNA modifications studies below.</span></p> <p><span style="font-weight: 400;">Diagenode’s highly validated antibodies:</span></p> <ul> <li>Highly sensitive and specific</li> <li>Cost-effective (requires less antibody per reaction)</li> <li>Batch-specific data is available on the website</li> <li>Expert technical support</li> <li>Sample sizes available</li> <li>100% satisfaction guarantee</li> </ul> </div> </div>', 'no_promo' => false, 'in_menu' => true, 'online' => true, 'tabular' => false, 'hide' => true, 'all_format' => false, 'is_antibody' => true, 'slug' => 'rna-modifications-antibodies', 'cookies_tag_id' => null, 'meta_keywords' => 'm6A polyclonal antibody ,Monoclonal antibody', 'meta_description' => 'Diagenode offers a wide range of RNA modifications antibodies', 'meta_title' => 'RNA modifications antibodies | Diagenode.com', 'modified' => '2020-09-01 11:43:28', 'created' => '2016-02-15 10:58:08', 'ProductsCategory' => array( [maximum depth reached] ), 'CookiesTag' => array([maximum depth reached]) ), (int) 1 => array( 'id' => '103', 'position' => '0', 'parent_id' => '4', 'name' => 'All antibodies', 'description' => '<p><span style="font-weight: 400;">All Diagenode’s antibodies are listed below. 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'36', 'position' => '10', 'parent_id' => '40', 'name' => 'RIP', 'description' => '<p>RIP</p>', 'in_footer' => false, 'in_menu' => false, 'online' => true, 'tabular' => true, 'slug' => 'rip', 'meta_keywords' => 'RIP antibodies,classic monoclonal antibodies,Ago (Argonautes) monoclonal antibody,Snf2h monoclonal antibody - Classic,Diagenode', 'meta_description' => 'Diagenode offers a wide range of classic monoclonal RIP antibodies.', 'meta_title' => 'RIP antibodies | Diagenode', 'modified' => '2016-01-21 08:09:31', 'created' => '2015-07-08 13:54:45', 'ProductsApplication' => array( 'id' => '5384', 'product_id' => '3166', 'application_id' => '36' ) ) $slugs = array( (int) 0 => 'rip' ) $applications = array( 'id' => '36', 'position' => '10', 'parent_id' => '40', 'name' => 'RIP', 'description' => '<p>RIP</p>', 'in_footer' => false, 'in_menu' => false, 'online' => true, 'tabular' => true, 'slug' => 'rip', 'meta_keywords' => 'RIP antibodies,classic monoclonal antibodies,Ago (Argonautes) monoclonal antibody,Snf2h monoclonal antibody - Classic,Diagenode', 'meta_description' => 'Diagenode offers a wide range of classic monoclonal RIP antibodies.', 'meta_title' => 'RIP antibodies | Diagenode', 'modified' => '2016-01-21 08:09:31', 'created' => '2015-07-08 13:54:45', 'locale' => 'eng' ) $description = '<p>RIP</p>' $name = 'RIP' $document = array( 'id' => '1117', 'name' => 'Datasheet Inosine Antibody C15200251', 'description' => '', 'image_id' => null, 'type' => 'Datasheet', 'url' => 'files/products/antibodies/Datasheet_inosine_C15200251.pdf', 'slug' => 'inosine-monoclonal-antibody-datasheet', 'meta_keywords' => '', 'meta_description' => '', 'modified' => '2020-12-11 09:47:05', 'created' => '2020-12-10 17:34:39', 'ProductsDocument' => array( 'id' => '3061', 'product_id' => '3166', 'document_id' => '1117' ) ) $sds = array( 'id' => '970', 'name' => 'Inosine Antibody SDS BE nl', 'language' => 'nl', 'url' => 'files/SDS/Inosine/SDS-C15200251-Inosine_Antibody-BE-nl-GHS_1_0.pdf', 'countries' => 'BE', 'modified' => '2021-01-12 16:38:24', 'created' => '2021-01-12 16:38:24', 'ProductsSafetySheet' => array( 'id' => '1698', 'product_id' => '3166', 'safety_sheet_id' => '970' ) )include - APP/View/Products/view.ctp, line 755 View::_evaluate() - CORE/Cake/View/View.php, line 971 View::_render() - CORE/Cake/View/View.php, line 933 View::render() - CORE/Cake/View/View.php, line 473 Controller::render() - CORE/Cake/Controller/Controller.php, line 963 ProductsController::slug() - APP/Controller/ProductsController.php, line 1052 ReflectionMethod::invokeArgs() - [internal], line ?? Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491 Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193 Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167 [main] - APP/webroot/index.php, line 118
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