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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Type I interferons regulate eomesodermin expression and the develop...
Published: May, 2015
Abstract: CD8(+) T-cell memory phenotype and function are acquired after antigen-driven activation. Memory-like cells may also arise in absence of antigenic ... Read more »
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Bioruptor Chromatin Shearing
Within-host diversity of MRSA antimicrobial resistances.
Published: May, 2015
Abstract: OBJECTIVES: MRSA is a major antimicrobial resistance (AMR) pathogen. The reservoir of infecting isolates is colonization, which is the site of evol... Read more »
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DNA shearing Bioruptor
The Basal Transcription Complex Component TAF3 Transduces Changes i...
Published: May, 2015
Abstract: Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how nuclear PI directly aff... Read more »
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Bioruptor Chromatin Shearing HighCell ChIP kit
Interaction with WDR5 Promotes Target Gene Recognition and Tumorige...
Published: May, 2015
Abstract: MYC is an oncoprotein transcription factor that is overexpressed in the majority of malignancies. The oncogenic potential of MYC stems from its abi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Supp. informations: Interaction with WDR5 Promotes Target Gene Reco...
Published: May, 2015
Abstract: MYC is an oncoprotein transcription factor that is overexpressed in the majority of malignancies. The oncogenic potential of MYC stems from its abi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Erosion of X Chromosome Inactivation in Human Pluripotent Cells Ini...
Published: May, 2015
Abstract: Human pluripotent stem cells (hPSCs) display extensive epigenetic instability, particularly on the X chromosome. In this study, we show that, in hP... Read more »
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Antibody
A genomewide catalogue of single nucleotide polymorphisms in white-...
Published: May, 2015
Abstract: The field of population genetics is rapidly moving into population genomics as the quantity of data generated by high-throughput sequencing platfor... Read more »
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DNA shearing Bioruptor
Widespread Proteome Remodeling and Aggregation in Aging C. elegans.
Published: May, 2015
Abstract: Aging has been associated with a progressive decline of proteostasis, but how this process affects proteome composition remains largely unexplored.... Read more »
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Cell Lysis
Non-coding RNA Generated following Lariat Debranching Mediates Targ...
Published: May, 2015
Abstract: Transcription through immunoglobulin switch (S) regions is essential for class switch recombination (CSR), but no molecular function of the transcr... Read more »
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Bioruptor Cell Lysis
Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di...
Published: May, 2015
Abstract: The MLL gene is a common target of chromosomal translocations found in human leukemia. MLL-fusion leukemia has a consistently poor outcome. One of ... Read more »
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Antibody
Uvrag targeting by Mir125a and Mir351 modulates autophagy associate...
Published: May, 2015
Abstract: The EWSR1 (EWS RNA-binding protein 1/Ewing Sarcoma Break Point Region 1) gene encodes a RNA/DNA binding protein that is ubiquitously expressed and ... Read more »
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Bioruptor
Evidence Supporting a Role for TopBP1 and Brd4 in the Initiation bu...
Published: May, 2015
Abstract: UNLABELLED: To replicate the double-stranded human papillomavirus 16 (HPV16) DNA genome, viral proteins E1 and E2 associate with the viral origin o... Read more »
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Bioruptor Chromatin Shearing Bioruptor Plus
Telomerase regulates MYC-driven oncogenesis independent of its reve...
Published: May, 2015
Abstract: Constitutively active MYC and reactivated telomerase often coexist in cancers. While reactivation of telomerase is thought to be essential for repl... Read more »
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Bioruptor Chromatin Shearing
Clinical application of whole-genome sequencing to inform treatment...
Published: May, 2015
Abstract: The treatment of drug-resistant tuberculosis cases is challenging, as drug options are limited, and the existing diagnostics are inadequate. Whole-... Read more »
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Bioruptor
Sensitive detection of chromatin-altering polymorphisms reveals aut...
Published: May, 2015
Abstract: Most disease associations detected by genome-wide association studies (GWAS) lie outside coding genes, but very few have been mapped to causal regu... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Regulation of chromatin accessibility and Zic binding at enhancers ...
Published: May, 2015
Abstract: To identify chromatin mechanisms of neuronal differentiation, we characterized chromatin accessibility and gene expression in cerebellar granule ne... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Microplex Library Preparation kit
A lncRNA regulates alternative splicing via establishment of a spli...
Published: May, 2015
Abstract: Alternative pre-mRNA splicing is a highly cell type-specific process essential to generating protein diversity. However, the mechanisms responsible... Read more »
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Bioruptor Chromatin Shearing Antibody H3K27me3 (C15410195)
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activate...
Published: May, 2015
Abstract: Technologies that enable targeted manipulation of epigenetic marks could be used to precisely control cell phenotype or interrogate the relationshi... Read more »
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Bioruptor Chromatin Shearing
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic ...
Published: May, 2015
Abstract: DNA methylation is a key epigenetic modification involved in regulating gene expression and maintaining genomic integrity. Here we inactivated all ... Read more »
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Antibody 5mC (C15200081)
C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
Published: May, 2015
Abstract: Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors. However, for most C2H2-ZF proteins it... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Linking the aryl hydrocarbon receptor with altered DNA methylation ...
Published: May, 2015
Abstract: Successfully fighting infection requires a properly tuned immune system. Recent epidemiological studies link exposure to pollutants that bind the a... Read more »
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Bioruptor Chromatin Shearing
Global regulation of heterochromatin spreading by Leo1.
Published: May, 2015
Abstract: Heterochromatin plays important roles in eukaryotic genome regulation. However, the repressive nature of heterochromatin combined with its propensi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Development of microsatellite primers in the protected species Viol...
Published: May, 2015
Abstract: PREMISE OF THE STUDY: Viola elatior (Violaceae) is a Eurasian perennial plant species in which French populations are threatened by anthropogenic p... Read more »
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DNA shearing Bioruptor
The interaction of mycobacterial protein Rv2966c with host chromati...
Published: April, 2015
Abstract: To effectively modulate the gene expression within an infected mammalian cell, the pathogen Mycobacterium tuberculosis would need to bring about ep... Read more »
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Bioruptor Chromatin Shearing IP-Star Antibody IP-Star Compact
Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogen...
Published: April, 2015
Abstract: Hepatocellular carcinoma (HCC) is a worldwide threat to public health, especially in China, where chronic hepatitis B virus (HBV) infection is foun... Read more »
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Bioruptor Chromatin Shearing
Th17 cells transdifferentiate into regulatory T cells during resolu...
Published: April, 2015
Abstract: Inflammation is a beneficial host response to infection but can contribute to inflammatory disease if unregulated. The Th17 lineage of T helper (Th... Read more »
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DNA shearing Bioruptor
The preRC protein ORCA organizes heterochromatin by assembling hist...
Published: April, 2015
Abstract: Heterochromatic domains are enriched with repressive histone marks, including histone H3 lysine 9 methylation, written by lysine methyltransferases... Read more »
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Chromatin Shearing
Identification of Critical Elements for Regulation of Inorganic Pyr...
Published: April, 2015
Abstract: Cytosolic inorganic pyrophosphatase plays an important role in the cellular metabolism by hydrolyzing inorganic pyrophosphate (PPi) formed as a by-... Read more »
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Antibody
Transcriptional activation by the thyroid hormone receptor through ...
Published: April, 2015
Abstract: A bimodal switch model is widely used to describe transcriptional regulation by the thyroid hormone receptor (TR). In this model, the unliganded TR... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I
Published: April, 2015
Abstract: Spt6 has many roles in transcription initiation and elongation by RNA polymerase (Pol) II. These effects are mediated through interactions with his... Read more »
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Bioruptor Chromatin Shearing

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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