DNA methylation:
overcoming
early detection
challenges in cancer

Capturing biomarkers in real-time with liquid biopsy

Using cell-free DNA (cfDNA) isolated from plasma, biomarkers were monitored in real-time in the risk population.

We helped identify the best sample prep options in terms of quantity, quality, reproducibility and high-throughput for regular screening of cfDNA from plasma.

DNA methylation for cancer classification

Genome-wide methylation profiles from healthy and cancer patients were created to identify potential biomarkers.

Using our WGBS/EM-seq service, UDx identified DNA methylation patterns associated with each CRC grade.

Validating biomarkers for performance

Once a pool of potential biomarkers was available, we identified the best performers.

Thanks to our Targeted Methyl-seq service, UDx narrowed down the candidates, and we validated a set of biomarkers that performs reliably with an NGS assay.