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<p><small><strong>Figure 1. Western blot analysis using the Diagenode monoclonal antibody directed against hRbAp46/48</strong> <br />Western blot was performed using nuclear extracts from HeLa cells (HeLa NE, 20 μg) and the Diagenode monoclonal antibody against hRbAp46/48 (cat# MAb-033-050) diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the left), the position of the protein of interest is shown on the right.<small></small></small></p>
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<p>Learn more about: <a href="https://www.diagenode.com/applications/western-blot">Loading control, MW marker visualization</a><em>. <br /></em></p>
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<p><small><strong>Figure 1. Western blot analysis using the Diagenode monoclonal antibody directed against hRbAp46/48</strong> <br />Western blot was performed using nuclear extracts from HeLa cells (HeLa NE, 20 μg) and the Diagenode monoclonal antibody against hRbAp46/48 (cat# MAb-033-050) diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the left), the position of the protein of interest is shown on the right.<small></small></small></p>
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'description' => 'RbAp48 (UniProtKB/Swiss-Prot entry Q09028) is a component of several complexes which regulate chromatin metabolism. These include (1) the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; (2) the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; (3) the nucleosome remodelling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; (4) the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and (5) the NURF (nucleosome remodeling factor) complex. Therefore it may target chromatin assembly factors as well as chromatin remodeling factors and histone deacetylases to their histone substrates in a nucleosomal DNA dependent manner.',
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'description' => 'Datasheet description',
'image_id' => null,
'type' => 'Datasheet',
'url' => 'files/products/antibodies/Datasheet_hRbAp46-48_MAb-033-050.pdf',
'slug' => 'datasheet-hrbap46-48-mab-033-050',
'meta_keywords' => null,
'meta_description' => null,
'modified' => '2015-07-07 11:47:44',
'created' => '2015-07-07 11:47:44',
'ProductsDocument' => array(
'id' => '906',
'product_id' => '1974',
'document_id' => '635'
)
)
$sds = array(
'id' => '3293',
'name' => 'SDS C15200033 RbAp 46/48 Antibody FR fr',
'language' => 'fr',
'url' => 'files/SDS/RbAp/SDS-C15200033-RbAp_46_48_Antibody-FR-fr-GHS_1_0.pdf',
'countries' => 'FR',
'modified' => '2024-01-11 12:31:16',
'created' => '2024-01-11 12:31:16',
'ProductsSafetySheet' => array(
'id' => '5350',
'product_id' => '1974',
'safety_sheet_id' => '3293'
)
)include - APP/View/Products/view.ctp, line 755
View::_evaluate() - CORE/Cake/View/View.php, line 971
View::_render() - CORE/Cake/View/View.php, line 933
View::render() - CORE/Cake/View/View.php, line 473
Controller::render() - CORE/Cake/Controller/Controller.php, line 963
ProductsController::slug() - APP/Controller/ProductsController.php, line 1052
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 491
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 193
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167
[main] - APP/webroot/index.php, line 118
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