Diagenode

MethylCap protein

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Catalog Number
Format
Price
C02020012
(mbd-001-100)
100 µg
DISCONTINUED

The MethylCap protein has been extensively validated for specific isolation of DNA fragments containing methylated CpGs. It consists of the methyl-CpG-binding domain (MBD) of human MeCP2, as a C-terminal fusion with Glutathione-S-transferase (GST) containing an N-terminal His6-tag. A single fully methylated CpG is sufficient for the interaction between the MethylCap protein and methylated DNA fragments.

  •  Documents
    Datasheet MethylCap Protein DATASHEET
    The MethylCap protein has been extensively validated for specific isolation of DNA fragments cont...
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  •  Safety sheets
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  •  Publications

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    Prenatal Exposure to DEHP Affects Spermatogenesis and Sperm DNA Methylation in a Strain-Dependent Manner.
    Prados J, Stenz L, Somm E, Stouder C, Dayer A, Paoloni-Giacobino A
    Di-(2-ethylhexyl)phtalate (DEHP) is a plasticizer with endocrine disrupting properties found ubiquitously in the environment and altering reproduction in rodents. Here we investigated the impact of prenatal exposure to DEHP on spermatogenesis and DNA sperm methylation in two distinct, selected, and sequenced mice st...

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