Protein extraction from tissues and cultured cells is the first step for many biochemical and analytical techniques (PAGE, Western blotting, mass spectrometry, etc.) or protein purification. Efficient disruption and homogenization of animal tissues and cultured cells are required to ensure high yields of proteins. Diagenode’s Bioruptor® Pico uses state-of-the-art ultrasound technology to efficiently disrupt and homogenize tissues and cultured cells in just one step.