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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genotyping 1000 yeast strains by next-generation sequencing.
Published: January, 2013
Abstract: BACKGROUND: The throughput of next-generation sequencing machines has increased dramatically over the last few years; yet the cost and time for lib... Read more »
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for ...
Published: January, 2013
Abstract: Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role ... Read more »
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Bioruptor
The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control Cwl...
Published: January, 2013
Abstract: The WalRK (YycFG) two-component system co-ordinates cell wall metabolism with growth by regulating expression of autolysins and proteins that modul... Read more »
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Bioruptor Chromatin Shearing
A pair of transposons coordinately suppresses gene expression, inde...
Published: January, 2013
Abstract: Our knowledge is limited regarding mechanisms by which transposable elements control host gene expression. Two Antirrhinum lines, HAM2 and HAM5, sh... Read more »
Bridging Decapentaplegic and Wingless signaling in Drosophila wings...
Published: January, 2013
Abstract: Wnts and bone morphogenetic proteins (BMPs) are signaling elements that are crucial for a variety of events in animal development. In Drosophila, W... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of differentially methylated regions using streptavi...
Published: January, 2013
Abstract: We have developed a method that enriches for methylated cytosines by capturing the fraction of bisulfite-treated DNA with unconverted cytosines. Th... Read more »
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DNA shearing Bioruptor
53BP1 Alters the Landscape of DNA Rearrangements and Suppresses AID...
Published: January, 2013
Abstract: Deficiencies in factors that regulate the DNA damage response enhance the incidence of malignancy by destabilizing the genome. However, the precise... Read more »
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DNA shearing Bioruptor
Vorinostat Induces Apoptosis and Differentiation in Myeloid Maligna...
Published: January, 2013
Abstract: Background Aberrant epigenetic patterns are central in the pathogenesis of haematopoietic diseases such as myelodysplastic syndromes (MDS) and acu... Read more »
ATR-like kinase Mec1 facilitates both chromatin accessibility at DN...
Published: January, 2013
Abstract: Faithful DNA replication is essential for normal cell division and differentiation. In eukaryotic cells, DNA replication takes place on chromatin. ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Autologous platelet-poor plasma decreases the bronchial stump necro...
Published: January, 2013
Abstract: Background: Necrosis of the bronchial stump is a very important trigger for bronchopleural fistula. The administration of local autologous platelet... Read more »
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Master Mix
Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting...
Published: December, 2012
Abstract: Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment progra... Read more »
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DNA shearing Bioruptor
The N-terminal segment of Plasmodium falciparum SURFIN(4.1) is requ...
Published: December, 2012
Abstract: Plasmodium falciparum SURFIN is a type I transmembrane protein that shares domains with molecules expressed on the surface of the red blood cells (... Read more »
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Antibody
Poised RNA Polymerase II Changes over Developmental Time and Prepar...
Published: December, 2012
Abstract: Poised RNA polymerase II (Pol II) is predominantly found at developmental control genes and is thought to allow their rapid and synchronous inducti... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Evolution of cichlid vision via trans-regulatory divergence.
Published: December, 2012
Abstract: ABSTRACT: BACKGROUND: Phenotypic evolution may occur through mutations that affect either the structure or expression of protein-coding genes. Alth... Read more »
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DNA shearing Bioruptor Bioruptor Plus
The RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells a...
Published: December, 2012
Abstract: Enhancers play a central role in precisely regulating the expression of developmentally regulated genes. However, the machineries required for enha... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enrichment of meiotic recombination hotspot sequences by avidin cap...
Published: December, 2012
Abstract: About 40% of the hotspots for meiotic recombination contain the degenerate consensus sequence 5'-CCNCCNTNNCCNC-3'. Here we present a novel protocol... Read more »
NKX2-1 activation by SMAD2 signaling after definitive endoderm diff...
Published: December, 2012
Abstract: Expression of NKX2-1 is required to specify definitive endoderm to respiratory endoderm. However, the transcriptional regulation of NKX2-1 is not f... Read more »
Structural analysis of the genome of breast cancer cell line ZR-75-...
Published: December, 2012
Abstract: ABSTRACT: BACKGROUND: It has recently emerged that common epithelial cancers such as breast cancers have fusion genes like those in leukaemias. In ... Read more »
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DNA shearing Bioruptor
Next-Generation Sequencing Reveals Deep Intronic Cryptic ABCC8 and ...
Published: December, 2012
Abstract: Next-generation sequencing (NGS) enables analysis of the human genome on a scale previously unachievable by Sanger sequencing. Exome sequencing of ... Read more »
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DNA shearing Bioruptor
AMPK Is a Negative Regulator of the Warburg Effect and Suppresses T...
Published: December, 2012
Abstract: AMPK is a metabolic sensor that helps maintain cellular energy homeostasis. Despite evidence linking AMPK with tumor suppressor functions, the role... Read more »
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Bioruptor Cell Lysis
Epigenetic Regulation of Nestin Expression During Neurogenic Differ...
Published: December, 2012
Abstract: Adipose-tissue-derived stem cells (ASCs) have received considerable attention due to their easy access, expansion potential, and differentiation ca... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K27me3 (C15410069)
MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chr...
Published: December, 2012
Abstract: The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the CNS may differ from ... Read more »
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Antibody
A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells.
Published: December, 2012
Abstract: Factor-induced reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is inefficient, complicating mechanistic studies. Here, w... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-H...
Published: December, 2012
Abstract: Monoallelic point mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) and its mitochondrial homolog IDH2 can lead to elevated levels of 2-hydr... Read more »
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Bioruptor Cell Lysis Western Blot Bioruptor Plus
HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regu...
Published: December, 2012
Abstract: The NY-ESO1 gene is a cancer/testis antigen considered to be suitable target for the immunotherapy of human malignancies. Despite the identificatio... Read more »
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Bioruptor Chromatin Shearing MeDIP kit
A polycomb group protein is retained at specific sites on chromatin...
Published: December, 2012
Abstract: Epigenetic regulation of gene expression, including by Polycomb Group (PcG) proteins, may depend on heritable chromatin states, but how these state... Read more »
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DNA shearing Bioruptor Bioruptor Plus
Hypoxia-inducible Factor 1α regulates a Socs3-Stat3-adiponectin sig...
Published: December, 2012
Abstract: Obesity has been identified as a major risk factor for type 2 diabetes, characterized by insulin resistance in insulin target tissues. Hypoxia-indu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The EP300, KDM5A, KDM6A and KDM6B Chromatin Regulators Cooperate wi...
Published: December, 2012
Abstract: POU5F1 is essential for maintaining pluripotency in embryonic stem cells (ESCs). It has been reported that the constitutive activation of POU5F1 is... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Nano-MeDIP-seq: Methylome analysis using low DNA concentrations (Pr...
Published: December, 2012
Abstract: To understand the functional consequences of DNA methylation on phenotypic plasticity, a genome - wide analysis should be embraced. This in turn re... Read more »
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DNA shearing Bioruptor IP-Star
A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ER...
Published: December, 2012
Abstract: Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interl... Read more »
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Bioruptor Cell Lysis Western Blot

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