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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Artd1/Parp1 regulates reprogramming by transcriptional regulation o...
Published: August, 2013
Abstract: The recently established reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka, represents a valuabl... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor...
Published: August, 2013
Abstract: In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels in lymphoid malignancies. In a model for p185(BCR-ABL... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)
Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in...
Published: August, 2013
Abstract: IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of kerati... Read more »
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Bioruptor
A three-state model for the regulation of telomerase by TERRA and h...
Published: August, 2013
Abstract: Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which... Read more »
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Bioruptor
Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in ...
Published: August, 2013
Abstract: Polycomb Repressive Complex 2 (PRC2) mediates transcriptional silencing by catalyzing histone H3 lysine 27 trimethylation (H3K27me3), but its role ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-...
Published: August, 2013
Abstract: DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA ... Read more »
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DNA shearing Bioruptor MagMeDIP kit Antibody
Histone variant Htz1 promotes histone H3 acetylation to enhance nuc...
Published: August, 2013
Abstract: Nucleotide excision repair (NER) is critical for maintaining genome integrity. How chromatin dynamics are regulated to facilitate this process in c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Nanolipodendrosome-loaded glatiramer acetate and myogenic different...
Published: August, 2013
Abstract: BACKGROND: Muscular dystrophies consist of a number of juvenile and adult forms of complex disorders which generally cause weakness or efficiency d... Read more »
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Bioruptor Liposome Preparation
Quantification of biomass and cell motion in human pluripotent stem...
Published: August, 2013
Abstract: Somatic cell reprogramming to pluripotency requires an immediate increase in cell proliferation and reduction in cell size. It is unknown whether p... Read more »
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Master Mix
Model selection reveals control of cold signalling by evening-phase...
Published: August, 2013
Abstract: Circadian clocks confer advantages by restricting biological processes to certain times of day through the control of specific phased outputs. Cont... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mitochondrial genome linearization is a causative factor for cardio...
Published: August, 2013
Abstract: Aims: Mitofusin (Mfn) 2 redundantly promotes mitochondrial outer membrane tethering and organelle fusion with Mfn1, and uniquely functions as the m... Read more »
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DNA shearing Bioruptor
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial...
Published: August, 2013
Abstract: Pathogens dramatically affect host cell transcription programs for their own profit during infection, but in most cases, the underlying mechanisms ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
O-glycosylation as a novel control mechanism of peptidoglycan hydro...
Published: August, 2013
Abstract: Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal r... Read more »
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Bioruptor
Genome-wide profiling identifies a subset of methamphetamine (METH)...
Published: August, 2013
Abstract: BACKGROUND: METH is an illicit drug of abuse that influences gene expression in the rat striatum. Histone modifications regulate gene transcription... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Binding of TFIIIC to SINE Elements Controls the Relocation of Activ...
Published: August, 2013
Abstract: In neurons, the timely and accurate expression of genes in response to synaptic activity relies on the interplay between epigenetic modifications o... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene...
Published: August, 2013
Abstract: The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptiona...
Published: August, 2013
Abstract: Oncogenic signaling pathways regulate gene expression in part through epigenetic modification of chromatin including DNA methylation and histone mo... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Androgen Receptor Drives Transcription of Rat PACAP in Gonadotrope ...
Published: August, 2013
Abstract: Gonadotropin expression is precisely regulated within the hypothalamic-pituitary-gonadal axis through the complex interaction of neuropeptides, gon... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
High-throughput sequencing reveals principles of adeno-associated v...
Published: August, 2013
Abstract: Viral integrations are important in human biology, yet genome-wide integration profiles have not been determined for many viruses. Adeno-associated... Read more »
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DNA shearing Bioruptor
Diverse stresses dramatically alter genome-wide p53 binding and tra...
Published: August, 2013
Abstract: The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have tak... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Program Specificity for Ptf1a in Pancreas versus Neural Tube Develo...
Published: August, 2013
Abstract: The lineage-specific basic helix-loop-helix transcription factor Ptf1a is a critical driver for development of both the pancreas and nervous system... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Minotaur is critical for primary piRNA biogenesis.
Published: August, 2013
Abstract: Piwi proteins and their associated small RNAs are essential for fertility in animals. In part, this is due to their roles in guarding germ cell gen... Read more »
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DNA shearing Bioruptor
Early growth response 2 (Egr2) plays opposing roles in committing C...
Published: August, 2013
Abstract: Early growth response 2 (Egr2) is a zinc-finger transcription factor that acts as an important modulator of a variety of physiological processes, s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin tandem affinity purification sequencing.
Published: August, 2013
Abstract: Chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) is a widely used method for mapping the interactions of prot... Read more »
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Bioruptor Chromatin Shearing
Chromatin-modifying agents reactivate embryonic renal stem/progenit...
Published: August, 2013
Abstract: Abstract Recent studies have suggested that epigenetic modulation with chromatin-modifying agents can induce stemness and dedifferentiation and inc... Read more »
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DNA shearing Bioruptor
Rev-erb-α modulates skeletal muscle oxidative capacity by regulatin...
Published: August, 2013
Abstract: The nuclear receptor Rev-erb-α modulates hepatic lipid and glucose metabolism, adipogenesis and the inflammatory response in macrophages. We show h... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
BACH2 mediates negative selection and p53-dependent tumor suppressi...
Published: August, 2013
Abstract: The B cell-specific transcription factor BACH2 is required for affinity maturation of B cells. Here we show that Bach2-mediated activation of p53 i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Noncoding RNAs prevent spreading of a repressive histone mark.
Published: August, 2013
Abstract: Transcription of eukaryotic genomes is more widespread than was previously anticipated and results in the production of many non-protein-coding RNA... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prdm1a directly activates foxd3 and tfap2a during zebrafish neural ...
Published: August, 2013
Abstract: The neural crest comprises multipotent precursor cells that are induced at the neural plate border by a series of complex signaling and genetic int... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome wide association analysis of a founder population identified...
Published: July, 2013
Abstract: The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5-10% of the total observed variance is explaine... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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