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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Environmentally induced transgenerational epigenetic reprogramming ...
Published: July, 2013
Abstract: A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypi... Read more »
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Antibody
PP1α, PP1β and Wip-1 regulate H4S47 phosphorylation and deposition ...
Published: July, 2013
Abstract: Phosphorylation of histone H4 serine 47 (H4S47ph) is catalyzed by Pak2, a member of the p21-activated serine/threonine protein kinase (Pak) family ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Modifications of Chromatin Dynamics Control the Smad2 Pathway Activ...
Published: July, 2013
Abstract: Rationale: The activation of the Smad2 signaling pathway is thought to play an important role in human aneurysmal diseases as described by an impor... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Reciprocal regulation of hepatic and adipose lipogenesis by liver x...
Published: July, 2013
Abstract: Liver X receptors (LXRs) regulate lipogenesis and inflammation, but their contribution to the metabolic syndrome is unclear. We show that LXRs modu... Read more »
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Master Mix
Detection of histone modification by chromatin immunoprecipitation ...
Published: July, 2013
Abstract: Epigenetic modification such as DNA methylation and histone modification have important roles in gene regulation. Epigenetic modification can be al... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Submergence Confers Immunity Mediated by the WRKY22 Transcription F...
Published: July, 2013
Abstract: Transcriptional control plays an important role in regulating submergence responses in plants. Although numerous genes are highly induced during hy... Read more »
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Bioruptor Chromatin Shearing
Passaging Techniques and ROCK Inhibitor Exert Reversible Effects on...
Published: July, 2013
Abstract: Human embryonic stem cells (hESCs) are known for their potential usage in regenerative medicine, but also for handling sensitivity. Much effort has... Read more »
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Antibody LowCell ChIP kit H3K27me3 (C15410069)
The 26S proteasome drives trinucleotide repeat expansions.
Published: July, 2013
Abstract: Trinucleotide repeat (TNR) expansion is the causative mutation for at least 17 inherited neurological diseases. An important question in the field ... Read more »
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Cell Lysis Western Blot
Progesterone receptor induces bcl-x expression through intragenic b...
Published: July, 2013
Abstract: Steroid receptors were classically described for regulating transcription by binding to target gene promoters. However, genome-wide studies reveal ... Read more »
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Antibody
The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2...
Published: July, 2013
Abstract: The tumour-suppressor gene CDKN1A (encoding p21Waf/Cip1) is thought to be epigenetically repressed in cancer cells. FBI-1 (ZBTB7A) is a proto-oncog... Read more »
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MeDIP kit
Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell o...
Published: July, 2013
Abstract: The number of Schwann cells is fitted to axonal length in peripheral nerves. This relationship is lost when tumorigenic stimuli induce uncontrolled... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Human papillomavirus type 16 E7 oncoprotein induces a transcrip...
Published: July, 2013
Abstract: Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to deregulate immunity by suppressing the function of the doubl... Read more »
Changes in RNA polymerase II progression influence somatic hypermut...
Published: July, 2013
Abstract: Somatic hypermutation (SHM) of Ig genes is initiated by the activation-induced cytidine deaminase (AID), and requires target gene transcription. We... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Uniform, optimal signal processing of mapped deep-sequencing data.
Published: July, 2013
Abstract: Despite their apparent diversity, many problems in the analysis of high-throughput sequencing data are merely special cases of two general problems... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Genome-wide measurement of protein-DNA binding dynamics using compe...
Published: July, 2013
Abstract: Competition chromatin immunoprecipitation (competition ChIP) enables experimenters to measure protein-DNA dynamics at a single locus or across the ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Therapeutic targeting of NOTCH signaling ameliorates immune-mediate...
Published: July, 2013
Abstract: Severe aplastic anemia (AA) is a bone marrow (BM) failure (BMF) disease frequently caused by aberrant immune destruction of blood progenitors. Alth... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Proteomic and genomic approaches reveal critical functions of H3K9 ...
Published: July, 2013
Abstract: Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) involves a marked reorganization of chromatin. To identify post-translat... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The glucocorticoid receptor dimer interface allosterically transmit...
Published: July, 2013
Abstract: Glucocorticoid receptor (GR) binds to genomic response elements and regulates gene transcription with cell and gene specificity. Within a response ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenici...
Published: July, 2013
Abstract: Brain tumors represent the leading cause of childhood cancer mortality, of which medulloblastoma (MB) is the most frequent malignant tumor. Recent ... Read more »
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LowCell ChIP kit
Fragmentation of genomic DNA using microwave irradiation.
Published: July, 2013
Abstract: An unconventional approach for DNA fragmentation was investigated to explore its feasibility as an alternative to the existing DNA fragmentation te... Read more »
Constitutional trisomy 8 mosaicism as a model for epigenetic studie...
Published: July, 2013
Abstract: BACKGROUND: To investigate epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism (CT8M) as a model, enabling an... Read more »
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MagMeDIP kit
Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate At...
Published: July, 2013
Abstract: The chromosome 9p21 (Chr9p21) locus of coronary artery disease has been identified in the first surge of genome-wide association and is the stronge... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody Bioruptor Plus HighCell ChIP kit
Disease-Related Growth Factor and Embryonic Signaling Pathways Modu...
Published: July, 2013
Abstract: Coronary heart disease (CHD) is the leading cause of mortality in both developed and developing countries worldwide. Genome-wide association studie... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)
Stepwise activation of the ATR signaling pathway upon increasing re...
Published: July, 2013
Abstract: Breaks at common fragile sites (CFS) are a recognized source of genome instability in pre-neoplastic lesions, but how such checkpoint-proficient ce... Read more »
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Bioruptor Cell Lysis Western Blot
Stalled RNAP-II molecules bound to non-coding rDNA spacers are requ...
Published: July, 2013
Abstract: The correct distribution of nuclear domains is critical for the maintenance of normal cellular processes such as transcription and replication, whi... Read more »
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Bioruptor Cell Lysis
A temperature-responsive network links cell shape and virulence tra...
Published: July, 2013
Abstract: Survival at host temperature is a critical trait for pathogenic microbes of humans. Thermally dimorphic fungal pathogens, including Histoplasma cap... Read more »
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Bioruptor Chromatin Shearing
Zeb1 Regulates E-cadherin and Epcam (Epithelial Cell Adhesion Molec...
Published: June, 2013
Abstract: The ZEB1 transcription factor is best known as an inducer of epithelial-mesenchymal transitions (EMT) in cancer metastasis, acting through transcri... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The genomic landscape of the somatic linker histone subtypes h1.1 t...
Published: June, 2013
Abstract: Human cells contain five canonical, replication-dependent somatic histone H1 subtypes (H1.1, H1.2, H1.3, H1.4, and H1.5). Although they are key chr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Status epilepticus triggers early and late alterations in brain-der...
Published: June, 2013
Abstract: Status epilepticus (SE) triggers abnormal expression of genes in the hippocampus, such as glutamate receptor subunit epsilon-2 (Grin2b/Nr2b) and br... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Bivalent chromatin marks developmental regulatory genes in the mous...
Published: June, 2013
Abstract: Developmental regulatory genes have both activating (H3K4me3) and repressive (H3K27me3) histone modifications in embryonic stem cells (ESCs). This ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)

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