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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Satb1 regulates the self-renewal of hematopoietic stem cells by pro...
Published: May, 2013
Abstract: How hematopoietic stem cells (HSCs) coordinate the regulation of opposing cellular mechanisms such as self-renewal and differentiation commitment r... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Progesterone receptors induce FOXO1-dependent senescence in ovarian...
Published: May, 2013
Abstract: Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Liver x receptors protect from development of prostatic intra-epith...
Published: May, 2013
Abstract: LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence prolife... Read more »
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Antibody
Differential transcript isoform usage pre- and post-zygotic genome ...
Published: May, 2013
Abstract: BACKGROUND: Zebrafish embryos are transcriptionally silent until activation of the zygotic genome during the 10th cell cycle. Onset of transcriptio... Read more »
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Antibody
First evidence of DNA methylation in insect Tribolium castaneum: en...
Published: May, 2013
Abstract: DNA methylation has been studied in many eukaryotic organisms, in particular vertebrates, and was implicated in developmental and phenotypic variat... Read more »
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Antibody
G-quadruplex structures are stable and detectable in human genomic ...
Published: April, 2013
Abstract: The G-quadruplex is an alternative DNA structural motif that is considered to be functionally important in the mammalian genome for transcriptional... Read more »
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DNA shearing Bioruptor
Heterochromatin protein 1 promotes self-renewal and triggers regene...
Published: April, 2013
Abstract: Adult stem cells (ASCs) capable of self-renewal and differentiation confer the potential of tissues to regenerate damaged parts. Epigenetic regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Coordinate changes in histone modifications, mRNA levels, and metab...
Published: April, 2013
Abstract: Lipotoxicity is a presumed pathogenetic process whereby elevated circulating and stored lipids in type 2 diabetes cause pancreatic β-cell failure. ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Master Mix
Balancing of histone H3K4 methylation states by the Kdm5c/SMCX hist...
Published: April, 2013
Abstract: The functional organization of eukaryotic genomes correlates with specific patterns of histone methylations. Regulatory regions in genomes such as ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
A proteomic characterization of factors enriched at nascent DNA mol...
Published: April, 2013
Abstract: DNA replication is facilitated by multiple factors that concentrate in the vicinity of replication forks. Here, we developed an approach that combi... Read more »
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Bioruptor Chromatin Shearing
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosin...
Published: April, 2013
Abstract: TET dioxygenases successively oxidize 5-methylcytosine (5mC) in mammalian genomes to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-... Read more »
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DNA shearing Bioruptor
Placing the HIRA histone chaperone complex in the chromatin landscape.
Published: April, 2013
Abstract: The HIRA chaperone complex, comprised of HIRA, UBN1, and CABIN1, collaborates with histone-binding protein ASF1a to incorporate histone variant H3.... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic re...
Published: April, 2013
Abstract: Liver fibrosis is a reversible wound-healing response involving TGFβ1/SMAD activation of hepatic stellate cells (HSCs). It results from excessive d... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An Orally Bioavailable Chemical Probe of the Lysine Methyltransfera...
Published: April, 2013
Abstract: EZH2 or EZH1 is the catalytic subunit of the polycomb repressive complex 2 that catalyzes methylation of histone H3 lysine 27 (H3K27). The trimethy... Read more »
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Antibody
Mechanism of Polycomb recruitment to CpG islands revealed by inheri...
Published: April, 2013
Abstract: How the transcription repressing complex Polycomb interacts with transcriptional regulators at housekeeping genes in somatic cells is not well unde... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The response of human macrophages to β-glucans depends on the infla...
Published: April, 2013
Abstract: BACKGROUND: β-glucans are fungal cell wall components that bind to the C-type lectin-like receptor dectin-1. Polymorphisms of dectin-1 gene are ass... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Hypersensitive site 6 of the Th2 locus control region is essential ...
Published: April, 2013
Abstract: The T helper type 2 (Th2) cytokine genes Il4, Il5, and Il13 are contained within a 140-kb region of mouse chromosome 11 and their expression is con... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The developmental epigenomics toolbox: ChIP-seq and MethylCap-seq p...
Published: April, 2013
Abstract: Genome-wide profiling of DNA methylation and histone modifications answered many questions as to how the genes are regulated on a global scale and ... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody MethylCap H3K4me3 (C15410003)
Estradiol represses the G(D3) synthase gene ST8SIA1 expression in h...
Published: April, 2013
Abstract: Recent data have underlined a possible role of G(D3) synthase (GD3S) and complex gangliosides in Estrogen Receptor (ER) negative breast cancer prog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
MTA3 regulates CGB5 and Snail genes in trophoblast.
Published: April, 2013
Abstract: Secreted by the placental trophoblast, human chorionic gonadotropin (hCG) is an important hormone during pregnancy and is required for the maintena... Read more »
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LowCell ChIP kit
Association between living environment and human oral viral ecology.
Published: April, 2013
Abstract: The human oral cavity has an indigenous microbiota known to include a robust community of viruses. Very little is known about how oral viruses are ... Read more »
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DNA shearing Bioruptor
The complete targeted profile of the organic acid intermediates of ...
Published: April, 2013
Abstract: The quantitative profiling of the organic acid intermediates of the citric acid cycle (CAC) presents a challenge due to the lack of commercially av... Read more »
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Cell Lysis Mass Spectrometry
Nuclear retention of the transcription factor NLP7 orchestrates the...
Published: April, 2013
Abstract: Nitrate is both an important nutrient and a signalling molecule for plants. Although several components of the nitrate signalling pathway have been... Read more »
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IPure kit
Multiple mechanisms of action of pyridoxine in primary hyperoxaluri...
Published: April, 2013
Abstract: Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal... Read more »
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Bioruptor Cell Lysis
Gain-of-function mutant p53 downregulates miR-223 contributing to c...
Published: April, 2013
Abstract: Mutant p53 proteins are expressed at high frequency in human tumors and are associated with poor clinical prognosis and resistance to chemotherapeu... Read more »
Retinoic acid represses invasion and stem cell phenotype by inducti...
Published: April, 2013
Abstract: The mouse haematopoietic stem cell (SC) regulator Latexin (LXN) is the only known homologue of the retinoic acid receptor responder 1 (RARRES1) gen... Read more »
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Bioruptor Cell Lysis Western Blot
The histone demethylase Jmjd3 sequentially associates with the tran...
Published: April, 2013
Abstract: Stem cell differentiation depends on transcriptional activation driven by lineage-specific regulators as well as changes in chromatin organization.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Exit from pluripotency is gated by intracellular redistribution of ...
Published: April, 2013
Abstract: Factors that sustain self-renewal of mouse embryonic stem cells (ESCs) are well described. In contrast, the machinery regulating exit from pluripot... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Methylation-dependent and -independent genomic targeting principles...
Published: April, 2013
Abstract: To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution o... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Culture-Independent Sequence-Based Metage nomics Approach to the ...
Published: April, 2013
Abstract: Importance Identification of the bacterium responsible for an outbreak can aid in disease management. However, traditional culture-based diagnos... Read more »
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DNA shearing Bioruptor

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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