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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

High-throughput sequencing reveals principles of adeno-associated v...
Published: August, 2013
Abstract: Viral integrations are important in human biology, yet genome-wide integration profiles have not been determined for many viruses. Adeno-associated... Read more »
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DNA shearing Bioruptor
Diverse stresses dramatically alter genome-wide p53 binding and tra...
Published: August, 2013
Abstract: The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have tak... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Program Specificity for Ptf1a in Pancreas versus Neural Tube Develo...
Published: August, 2013
Abstract: The lineage-specific basic helix-loop-helix transcription factor Ptf1a is a critical driver for development of both the pancreas and nervous system... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Minotaur is critical for primary piRNA biogenesis.
Published: August, 2013
Abstract: Piwi proteins and their associated small RNAs are essential for fertility in animals. In part, this is due to their roles in guarding germ cell gen... Read more »
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DNA shearing Bioruptor
Early growth response 2 (Egr2) plays opposing roles in committing C...
Published: August, 2013
Abstract: Early growth response 2 (Egr2) is a zinc-finger transcription factor that acts as an important modulator of a variety of physiological processes, s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin tandem affinity purification sequencing.
Published: August, 2013
Abstract: Chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) is a widely used method for mapping the interactions of prot... Read more »
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Bioruptor Chromatin Shearing
Chromatin-modifying agents reactivate embryonic renal stem/progenit...
Published: August, 2013
Abstract: Abstract Recent studies have suggested that epigenetic modulation with chromatin-modifying agents can induce stemness and dedifferentiation and inc... Read more »
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DNA shearing Bioruptor
Rev-erb-α modulates skeletal muscle oxidative capacity by regulatin...
Published: August, 2013
Abstract: The nuclear receptor Rev-erb-α modulates hepatic lipid and glucose metabolism, adipogenesis and the inflammatory response in macrophages. We show h... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
BACH2 mediates negative selection and p53-dependent tumor suppressi...
Published: August, 2013
Abstract: The B cell-specific transcription factor BACH2 is required for affinity maturation of B cells. Here we show that Bach2-mediated activation of p53 i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Noncoding RNAs prevent spreading of a repressive histone mark.
Published: August, 2013
Abstract: Transcription of eukaryotic genomes is more widespread than was previously anticipated and results in the production of many non-protein-coding RNA... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prdm1a directly activates foxd3 and tfap2a during zebrafish neural ...
Published: August, 2013
Abstract: The neural crest comprises multipotent precursor cells that are induced at the neural plate border by a series of complex signaling and genetic int... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome wide association analysis of a founder population identified...
Published: July, 2013
Abstract: The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5-10% of the total observed variance is explaine... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Silencing MED1 sensitizes breast cancer cells to pure anti-estrogen...
Published: July, 2013
Abstract: Pure anti-estrogen fulvestrant has been shown to be a promising ER antagonist for locally advanced and metastatic breast cancer. Unfortunately, a s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Zfp819, a novel KRAB-zinc finger protein, interacts with KAP1 and f...
Published: July, 2013
Abstract: Pluripotency is maintained by both known and unknown transcriptional regulatory networks. In the present study, we have identified Zfp819, a KRAB-z... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Synchronous recruitment of epigenetic modifiers to endotoxin synerg...
Published: July, 2013
Abstract: BACKGROUND: As a consequence of acute kidney injury (AKI), proximal tubular cells hyperrespond to endotoxin (lipopolysaccharide, LPS) by exaggerate... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Differential programming of B cells in AID deficient mice.
Published: July, 2013
Abstract: The Aicda locus encodes the activation induced cytidine deaminase (AID) and is highly expressed in germinal center (GC) B cells to initiate somatic... Read more »
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MethylCap
STAT3 signaling induces the differentiation of human ICOS(+) CD4 T ...
Published: July, 2013
Abstract: The generation of high-affinity antibodies and the development of B cell memory are dependent on the help provided by CD4 T cells. Mouse studies in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNA unmethylome profiling by covalent capture of CpG sites.
Published: July, 2013
Abstract: Dynamic patterns of cytosine-5 methylation and successive hydroxylation are part of epigenetic regulation in eukaryotes, including humans, which co... Read more »
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DNA shearing Bioruptor MagMeDIP kit
VAL- and AtBMI1-Mediated H2Aub Initiate the Switch from Embryonic t...
Published: July, 2013
Abstract: Plant B3-domain transcription factors have an important role in regulating seed development, in particular seed maturation and germination [1]. Amo... Read more »
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Antibody H3K27me3 (C15410069)
Chromatin insulator bodies are nuclear structures that form in resp...
Published: July, 2013
Abstract: Chromatin insulators assist in the formation of higher-order chromatin structures by mediating long-range contacts between distant genomic sites. I... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNA methylation of dermal MSCs in psoriasis: Identification of epig...
Published: July, 2013
Abstract: BACKGROUND: Mesenchymal stem cells (MSCs) are likely involved in pathological processes of immune-related diseases, including psoriasis, because of... Read more »
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DNA shearing Bioruptor Antibody
Meta-analysis of IDH-mutant cancers identifies EBF1 as an interacti...
Published: July, 2013
Abstract: Isocitrate dehydrogenase (IDH) genes 1 and 2 are frequently mutated in acute myeloid leukaemia (AML), low-grade glioma, cholangiocarcinoma (CC) and... Read more »
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IP-Star
An epigenetic trap stabilizes singular olfactory receptor expression.
Published: July, 2013
Abstract: The molecular mechanisms regulating olfactory receptor (OR) expression in the mammalian nose are not yet understood. Here, we identify the transien... Read more »
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DNA shearing Bioruptor
Imprinted Chromatin around DIRAS3 Regulates Alternative Splicing of...
Published: July, 2013
Abstract: Imprinted gene clusters are regulated by long noncoding RNAs (lncRNAs), CCCTC binding factor (CTCF)-mediated boundaries, and DNA methylation. DIRAS... Read more »
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Antibody
Transcriptional profiling by RNA-Seq of peri-attachment porcine emb...
Published: July, 2013
Abstract: Substantial mortality of in vitro manipulated porcine embryos is observed during peri-attachment development. Herein we describe our efforts to cha... Read more »
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DNA shearing Bioruptor
Transgene- and locus-dependent imprinting reveals allele-specific c...
Published: July, 2013
Abstract: When positioned into the integrin α-6 gene, an Hoxd9lacZ reporter transgene displayed parental imprinting in mouse embryos. While the expression fr... Read more »
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Antibody
PfSec13 is an unusual chromatin-associated nucleoporin of Plasmodiu...
Published: July, 2013
Abstract: In Plasmodium falciparum, the deadliest form of human malaria, the nuclear periphery has drawn much attention due to its role as a sub-nuclear comp... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
STAT4 and T-bet are required for the plasticity of IFN-γ expression...
Published: July, 2013
Abstract: CD4(+) T cells developing toward a Th2 fate express IL-4, IL-5, and IL-13 while inhibiting production of cytokines associated with other Th types, ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Otx2 and onecut1 promote the fates of cone photoreceptors and horiz...
Published: July, 2013
Abstract: Cone photoreceptors carry out phototransduction in daylight conditions and provide the critical first step in color vision. Despite their importanc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Spatially distinct roles of class Ia PI3K isoforms in the developme...
Published: July, 2013
Abstract: PTEN hamartoma tumor syndrome (PHTS) comprises a collection of genetic disorders associated with germline mutations in the tumor suppressor gene PT... Read more »

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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