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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Alterations in Cellular Energy Metabolism Associated with the Antip...
Published: November, 2012
Abstract: KU-55933 is a specific inhibitor of the kinase activity of the protein encoded by Ataxia telangiectasia mutated (ATM), an important tumor suppresso... Read more »
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Bioruptor Cell Lysis
Reduced TOR signaling sustains hyphal development in Candida albica...
Published: November, 2012
Abstract: Candida albicans is able to undergo reversible morphological changes between yeast and hyphal forms in response to environmental cues. This morphol... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Two different high throughput sequencing approaches identify thousa...
Published: November, 2012
Abstract: High throughput sequencing technologies are being applied to an increasing number of model species with a high-quality reference genome. The applic... Read more »
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DNA shearing Bioruptor
Enhancer-associated H3K4 monomethylation by Trithorax-related, the ...
Published: November, 2012
Abstract: Monomethylation of histone H3 on Lys 4 (H3K4me1) and acetylation of histone H3 on Lys 27 (H3K27ac) are histone modifications that are highly enrich... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
T cell receptor stimulation-induced epigenetic changes and foxp3 ex...
Published: November, 2012
Abstract: The transcription factor Foxp3 is essential for the development of regulatory T (Treg) cells, yet its expression is insufficient for establishing t... Read more »
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MagMeDIP kit
HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Induc...
Published: November, 2012
Abstract: BACKGROUND: Although recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular u... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star IP-Star Compact
Retinoic acid dependent histone 3 demethylation of the clustered HO...
Published: November, 2012
Abstract: Gene activation of HOX clusters is an early event in embryonic development. These genes are highly expressed and been active in the vertebrate nerv... Read more »
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Histone ChIP kit
GADD45G Functions in Male Sex Determination by Promoting p38 Signal...
Published: November, 2012
Abstract: Male sex determination in mammals is induced by Sry, a gene whose regulation is poorly understood. Here we show that mice mutant for the stress-res... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Capturing native long-range contiguity by in situ library construct...
Published: November, 2012
Abstract: The relatively short read lengths associated with the most cost-effective DNA sequencing technologies have limited their use in de novo genome asse... Read more »
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DNA shearing Bioruptor
Timing of Transcriptional Quiescence during Gametogenesis Is Contro...
Published: November, 2012
Abstract: Gametes are among the most highly specialized cells produced during development. Although gametogenesis culminates in transcriptional quiescence in... Read more »
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DNA shearing Bioruptor
Vestigial-like 3 (Vgll3) is an Inhibitor of Adipocyte Differentiation.
Published: November, 2012
Abstract: Abstract Abstract Adipose differentiation is a complex process controlled by a network of transcription factors and co-regulators. We compared the... Read more »
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Master Mix
Altered Binding Site Selection of P53 Transcription Cassettes by He...
Published: November, 2012
Abstract: The key cellular regulator p53 is a common target of viral oncoproteins. However, the mechanism by which p53 transcription regulation is modulated ... Read more »
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Bioruptor Chromatin Shearing
Dysregulation of REST-regulated coding and non-coding RNAs in a cel...
Published: November, 2012
Abstract: Huntingtin (Htt) protein interacts with many transcriptional regulators, with widespread disruption to the transcriptome in Huntington's disease (H... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Protein Group Modification and Synergy in the SUMO Pathway as Exemp...
Published: November, 2012
Abstract: Protein modification by SUMO affects a wide range of protein substrates. Surprisingly, although SUMO pathway mutants display strong phenotypes, the... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)
UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencin...
Published: November, 2012
Abstract: piRNAs silence transposons during germline development. In Drosophila, transcripts from heterochromatic clusters are processed into primary piRNAs ... Read more »
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Bioruptor
Polycomb Group Proteins Bind an engrailed PRE in Both the "ON" and ...
Published: November, 2012
Abstract: Polycomb group (PcG) and trithorax Group (trxG) proteins maintain the "OFF" and "ON" transcriptional states of HOX genes and other targets by modul... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Inhibition of Tumor Promotion by Parthenolide: Epigenetic Modulatio...
Published: November, 2012
Abstract: The promotion stage in the multistep process of epidermal tumorigenesis is NF-кB-dependent, epigenetically regulated, and reversible, thus, a suita... Read more »
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Antibody
A Forward Genetic Screen Identifies Eukaryotic Translation Initiati...
Published: November, 2012
Abstract: We have used a forward genetic screen to identify genes required for transgene silencing in the mouse. Previously these genes were found using cand... Read more »
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DNA shearing Bioruptor
Epigenetic Silencing of Antiviral Genes Renders Clones of Huh-7 Cel...
Published: October, 2012
Abstract: Hepatitis C virus (HCV) does not replicate efficiently in wild-type human hepatoma Huh-7 cells, but it replicates robustly in certain subclones of ... Read more »
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MeDIP kit
Thalamus-derived molecules promote survival and dendritic growth of...
Published: October, 2012
Abstract: The mammalian neocortex is composed of various types of neurons that reflect its laminar and area structures. It has been suggested that not only i... Read more »
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Antibody
IL-23 is pro-proliferative, epigenetically regulated and modulated ...
Published: October, 2012
Abstract: BACKGROUND: IL-23 is a member of the IL-6 super-family and plays key roles in cancer. Very little is currently known about the role of IL-23 in non... Read more »
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Antibody H3K4me3 (C15410003)
Systematic identification of functional residues in mammalian histo...
Published: October, 2012
Abstract: The histone variant H2AX is a principal component of chromatin involved in the detection, signaling and repair of DNA double-strand breaks (DSBs). ... Read more »
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Bioruptor Cell Lysis Western Blot Bioruptor Plus
Piccolo NuA4 catalyzed acetylation of nucleosomal histones: critica...
Published: October, 2012
Abstract: Piccolo NuA4 is an essential yeast histone acetyltransferase (HAT) complex that targets histones H4 and H2A in nucleosome substrates. While Piccolo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of Pluripotency and Self- Renewal of ESCs through Epigen...
Published: October, 2012
Abstract: Embryonic stem cell (ESC) pluripotency requires bivalent epigenetic modifications of key developmental genes regulated by various transcription fac... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
TGFβ1-induced Baf60c regulates both smooth muscle cell commitment a...
Published: October, 2012
Abstract: Smooth muscle cells (SMCs) play critical roles in a number of diseases; however, the molecular mechanism underlying their development is unclear. A... Read more »
High-resolution detection of DNA binding sites of the global transc...
Published: October, 2012
Abstract: The transcriptional regulator GlxR has been characterised as a global hub within the gene-regulatory network of Corynebacterium glutamicum. Chromat... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
CpG islands and GC content dictate nucleosome depletion in a transc...
Published: October, 2012
Abstract: One clear hallmark of mammalian promoters is the presence of CpG islands (CGIs) at more than two-thirds of genes, whereas TATA boxes are only prese... Read more »
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DNA shearing Bioruptor
The H3K27 Demethylase JMJD3 Is Required for Maintenance of the Embr...
Published: October, 2012
Abstract: JMJD3 (KDM6B) antagonizes Polycomb silencing by demethylating lysine 27 on histone H3. The interplay of methyltransferases and demethylases at this... Read more »
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Bioruptor Cell Lysis Western Blot
HIF1α is a central regulator of collagen hydroxylation and secretio...
Published: October, 2012
Abstract: Collagen production is fundamental for the ontogeny and the phylogeny of all multicellular organisms. It depends on hydroxylation of proline residu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin acetylation at transcription start sites and vitamin D re...
Published: October, 2012
Abstract: The nuclear hormone 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3) or 1,25D) regulates its target genes via activation of the transcription factor v... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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