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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Rapid inactivation and proteasome-mediated degradation of OGG1 cont...
Published: January, 2013
Abstract: Inhibition of DNA repair has been proposed as a mechanism underlying heat-induced sensitization of tumour cells to some anticancer treatments. Base... Read more »
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Bioruptor
Myb-domain protein Teb1 controls histone levels and centromere asse...
Published: January, 2013
Abstract: The TTAGGG motif is common to two seemingly unrelated dimensions of chromatin function-the vertebrate telomere repeat and the promoter regions of m... Read more »
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Bioruptor Chromatin Shearing
Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD1...
Published: January, 2013
Abstract: ADP-ribosylation is a posttranslational modification regulating various physiological processes, including DNA damage repair, gene transcription, a... Read more »
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Bioruptor Cell Lysis
Characterization of the EZH2-MMSET Histone Methyltransferase Regula...
Published: January, 2013
Abstract: Histone methyltransferases (HMTases), as chromatin modifiers, regulate the transcriptomic landscape in normal development as well in diseases such ... Read more »
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HighCell ChIP kit
Pre-mRNA Splicing Is a Determinant of Nucleosome Organization
Published: January, 2013
Abstract: Chromatin organization affects alternative splicing and previous studies have shown that exons have increased nucleosome occupancy compared with th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestr...
Published: January, 2013
Abstract: Embryonic development is characterized by dynamic changes in gene expression, yet the role of chromatin remodeling in these cellular transitions re... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Histone methyltransferase MLL3 contributes to genome-scale circadia...
Published: January, 2013
Abstract: Daily cyclical expression of thousands of genes in tissues such as the liver is orchestrated by the molecular circadian clock, the disruption of wh... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 ...
Published: January, 2013
Abstract: The nuclear receptor peroxisome proliferator-activated receptor (PPAR)α is primarily known as a regulator of fatty acid metabolism, energy balance,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Comprehensive histone phosphorylation analysis and identification o...
Published: January, 2013
Abstract: The important role of histone posttranslational modifications, particularly methylation and acetylation, in Plasmodium falciparum gene regulation h... Read more »
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Bioruptor Cell Lysis
Identification and analysis of the proximal promoters of microRNA g...
Published: January, 2013
Abstract: Endogenous microRNAs (miRNAs) modulate gene expression at the post-transcription level. In plants, a vast majority of MIR genes are thought to be t... Read more »
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Bioruptor Chromatin Shearing
Bone marrow NR4A expression is not a dominant factor in the develop...
Published: January, 2013
Abstract: The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolic pathways. We previously... Read more »
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Master Mix
The Roles of Whole-Genome and Small-Scale Duplications in the Funct...
Published: January, 2013
Abstract: Researchers have long been enthralled with the idea that gene duplication can generate novel functions, crediting this process with great evolution... Read more »
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DNA shearing Bioruptor
Genotyping 1000 yeast strains by next-generation sequencing.
Published: January, 2013
Abstract: BACKGROUND: The throughput of next-generation sequencing machines has increased dramatically over the last few years; yet the cost and time for lib... Read more »
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for ...
Published: January, 2013
Abstract: Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role ... Read more »
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Bioruptor
The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control Cwl...
Published: January, 2013
Abstract: The WalRK (YycFG) two-component system co-ordinates cell wall metabolism with growth by regulating expression of autolysins and proteins that modul... Read more »
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Bioruptor Chromatin Shearing
A pair of transposons coordinately suppresses gene expression, inde...
Published: January, 2013
Abstract: Our knowledge is limited regarding mechanisms by which transposable elements control host gene expression. Two Antirrhinum lines, HAM2 and HAM5, sh... Read more »
Bridging Decapentaplegic and Wingless signaling in Drosophila wings...
Published: January, 2013
Abstract: Wnts and bone morphogenetic proteins (BMPs) are signaling elements that are crucial for a variety of events in animal development. In Drosophila, W... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of differentially methylated regions using streptavi...
Published: January, 2013
Abstract: We have developed a method that enriches for methylated cytosines by capturing the fraction of bisulfite-treated DNA with unconverted cytosines. Th... Read more »
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DNA shearing Bioruptor
53BP1 Alters the Landscape of DNA Rearrangements and Suppresses AID...
Published: January, 2013
Abstract: Deficiencies in factors that regulate the DNA damage response enhance the incidence of malignancy by destabilizing the genome. However, the precise... Read more »
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DNA shearing Bioruptor
Vorinostat Induces Apoptosis and Differentiation in Myeloid Maligna...
Published: January, 2013
Abstract: Background Aberrant epigenetic patterns are central in the pathogenesis of haematopoietic diseases such as myelodysplastic syndromes (MDS) and acu... Read more »
ATR-like kinase Mec1 facilitates both chromatin accessibility at DN...
Published: January, 2013
Abstract: Faithful DNA replication is essential for normal cell division and differentiation. In eukaryotic cells, DNA replication takes place on chromatin. ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Autologous platelet-poor plasma decreases the bronchial stump necro...
Published: January, 2013
Abstract: Background: Necrosis of the bronchial stump is a very important trigger for bronchopleural fistula. The administration of local autologous platelet... Read more »
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Master Mix
Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting...
Published: December, 2012
Abstract: Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment progra... Read more »
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DNA shearing Bioruptor
The N-terminal segment of Plasmodium falciparum SURFIN(4.1) is requ...
Published: December, 2012
Abstract: Plasmodium falciparum SURFIN is a type I transmembrane protein that shares domains with molecules expressed on the surface of the red blood cells (... Read more »
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Antibody
Poised RNA Polymerase II Changes over Developmental Time and Prepar...
Published: December, 2012
Abstract: Poised RNA polymerase II (Pol II) is predominantly found at developmental control genes and is thought to allow their rapid and synchronous inducti... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Evolution of cichlid vision via trans-regulatory divergence.
Published: December, 2012
Abstract: ABSTRACT: BACKGROUND: Phenotypic evolution may occur through mutations that affect either the structure or expression of protein-coding genes. Alth... Read more »
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DNA shearing Bioruptor Bioruptor Plus
The RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells a...
Published: December, 2012
Abstract: Enhancers play a central role in precisely regulating the expression of developmentally regulated genes. However, the machineries required for enha... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enrichment of meiotic recombination hotspot sequences by avidin cap...
Published: December, 2012
Abstract: About 40% of the hotspots for meiotic recombination contain the degenerate consensus sequence 5'-CCNCCNTNNCCNC-3'. Here we present a novel protocol... Read more »
NKX2-1 activation by SMAD2 signaling after definitive endoderm diff...
Published: December, 2012
Abstract: Expression of NKX2-1 is required to specify definitive endoderm to respiratory endoderm. However, the transcriptional regulation of NKX2-1 is not f... Read more »
Structural analysis of the genome of breast cancer cell line ZR-75-...
Published: December, 2012
Abstract: ABSTRACT: BACKGROUND: It has recently emerged that common epithelial cancers such as breast cancers have fusion genes like those in leukaemias. In ... Read more »
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DNA shearing Bioruptor

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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