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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Notch pathway activation targets AML-initiating cell homeostasis an...
Published: January, 2013
Abstract: Notch signaling pathway activation is known to contribute to the pathogenesis of a spectrum of human malignancies, including T cell leukemia. Howev... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cell Cycle-Dependent Recruitment of Polycomb Proteins to the ASNS P...
Published: January, 2013
Abstract: Epigenetic modifiers and transcription factors contribute to developmentally programmed gene expression. Here, we establish a functional link betwe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin signatures and retrotransposon profiling in mouse embryos...
Published: January, 2013
Abstract: How a more plastic chromatin state is maintained and reversed during development is unknown. Heterochromatin-mediated silencing of repetitive eleme... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)
Bookmarking by specific and nonspecific binding of FoxA1 pioneer fa...
Published: January, 2013
Abstract: While most transcription factors exit the chromatin during mitosis and the genome becomes silent, a subset of factors remains and "bookmarks" genes... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Targeted multiplex next-generation sequencing: advances in techniqu...
Published: January, 2013
Abstract: Next-generation sequencing (NGS) is emerging as an efficient and cost-effective tool in population genomic analyses of nonmodel organisms, allowing... Read more »
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DNA shearing Bioruptor
MeCP2 modulates gene expression pathways in astrocytes.
Published: January, 2013
Abstract: ABSTRACT: BACKGROUND: Mutations in MECP2 encoding methyl-CpG-binding protein 2 (MeCP2) cause the X-linked neurodevelopmental disorder Rett syndrome... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational in...
Published: January, 2013
Abstract: Environmental compounds have been shown to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine... Read more »
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Antibody
Valproic acid inhibits the proliferation of cancer cells by re-expr...
Published: January, 2013
Abstract: In this study, primary murine prostate cancer (PCa) cells were derived using the well-established TRAMP model (transgenic adenocarcinoma mouse pros... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Plastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Ep...
Published: January, 2013
Abstract: Environmental compounds are known to promote epigenetic transgenerational inheritance of adult onset disease in subsequent generations (F1–F3) foll... Read more »
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Antibody
An in vivo hypoxia metagene identifies the novel hypoxia inducible ...
Published: January, 2013
Abstract: A hypoxia-associated gene signature (metagene) was previously derived via in vivo data-mining. In this study, we aimed to investigate whether this ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
SIRT1 Positively Regulates Breast Cancer Associated Human Aromatase...
Published: January, 2013
Abstract: Breast cancer remains one of the leading causes of death in women diagnosed with cancer. In breast cancer, aberrant expression of the CYP19A1 gene,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineag...
Published: January, 2013
Abstract: Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. He... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
In Vivo Epigenomic Profiling of Germ Cells Reveals Germ Cell Molecu...
Published: January, 2013
Abstract: The limited number of in vivo germ cells poses an impediment to genome-wide studies. Here, we applied a small-scale chromatin immunoprecipitation s... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene...
Published: January, 2013
Abstract: The Mixed Lineage Leukemia (MLL) protein is an important epigenetic regulator required for the maintenance of gene activation during development. M... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dual function of MIPS1 as a metabolic enzyme and transcriptional re...
Published: January, 2013
Abstract: Because regulation of its activity is instrumental either to support cell proliferation and growth or to promote cell death, the universal myo-inos... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit
The SIRT1 Modulators AROS and DBC1 Regulate HSF1 Activity and the H...
Published: January, 2013
Abstract: The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligode...
Published: January, 2013
Abstract: Establishment of oligodendrocyte identity is crucial for subsequent events of myelination in the CNS. Here, we demonstrate that activation of ATP-d... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Mechanism of competence activation by the ComRS signaling system in...
Published: January, 2013
Abstract: In many streptococci, competence for natural DNA transformation is regulated by the Rgg-type regulator ComR and the pheromone ComS, which is sensed... Read more »
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Bioruptor Cell Lysis
Rapid inactivation and proteasome-mediated degradation of OGG1 cont...
Published: January, 2013
Abstract: Inhibition of DNA repair has been proposed as a mechanism underlying heat-induced sensitization of tumour cells to some anticancer treatments. Base... Read more »
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Bioruptor
Myb-domain protein Teb1 controls histone levels and centromere asse...
Published: January, 2013
Abstract: The TTAGGG motif is common to two seemingly unrelated dimensions of chromatin function-the vertebrate telomere repeat and the promoter regions of m... Read more »
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Bioruptor Chromatin Shearing
Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD1...
Published: January, 2013
Abstract: ADP-ribosylation is a posttranslational modification regulating various physiological processes, including DNA damage repair, gene transcription, a... Read more »
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Bioruptor Cell Lysis
Characterization of the EZH2-MMSET Histone Methyltransferase Regula...
Published: January, 2013
Abstract: Histone methyltransferases (HMTases), as chromatin modifiers, regulate the transcriptomic landscape in normal development as well in diseases such ... Read more »
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HighCell ChIP kit
Pre-mRNA Splicing Is a Determinant of Nucleosome Organization
Published: January, 2013
Abstract: Chromatin organization affects alternative splicing and previous studies have shown that exons have increased nucleosome occupancy compared with th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestr...
Published: January, 2013
Abstract: Embryonic development is characterized by dynamic changes in gene expression, yet the role of chromatin remodeling in these cellular transitions re... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Histone methyltransferase MLL3 contributes to genome-scale circadia...
Published: January, 2013
Abstract: Daily cyclical expression of thousands of genes in tissues such as the liver is orchestrated by the molecular circadian clock, the disruption of wh... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 ...
Published: January, 2013
Abstract: The nuclear receptor peroxisome proliferator-activated receptor (PPAR)α is primarily known as a regulator of fatty acid metabolism, energy balance,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Comprehensive histone phosphorylation analysis and identification o...
Published: January, 2013
Abstract: The important role of histone posttranslational modifications, particularly methylation and acetylation, in Plasmodium falciparum gene regulation h... Read more »
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Bioruptor Cell Lysis
Identification and analysis of the proximal promoters of microRNA g...
Published: January, 2013
Abstract: Endogenous microRNAs (miRNAs) modulate gene expression at the post-transcription level. In plants, a vast majority of MIR genes are thought to be t... Read more »
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Bioruptor Chromatin Shearing
Bone marrow NR4A expression is not a dominant factor in the develop...
Published: January, 2013
Abstract: The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolic pathways. We previously... Read more »
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Master Mix
The Roles of Whole-Genome and Small-Scale Duplications in the Funct...
Published: January, 2013
Abstract: Researchers have long been enthralled with the idea that gene duplication can generate novel functions, crediting this process with great evolution... Read more »
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DNA shearing Bioruptor

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