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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Association of UHRF1 with methylated H3K9 directs the maintenance o...
Published: September, 2012
Abstract: A fundamental challenge in mammalian biology has been the elucidation of mechanisms linking DNA methylation and histone post-translational modifica... Read more »
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Antibody 5mC (C15200081)
FRUIT, a Scar-Free System for Targeted Chromosomal Mutagenesis, Epi...
Published: September, 2012
Abstract: Recombineering is a widely-used approach to delete genes, introduce insertions and point mutations, and introduce epitope tags into bacterial chrom... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Quantitative Proteomic Workflow for Characterization of Frozen Cl...
Published: September, 2012
Abstract: This paper describes a simple, highly efficient and robust proteomic workflow for routine liquid-chromatography tandem mass spectrometry analysis o... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
PML promotes MHC class II gene expression by stabilizing the class ...
Published: September, 2012
Abstract: Promyelocytic leukemia (PML) nuclear bodies selectively associate with transcriptionally active genomic regions, including the gene-rich major hist... Read more »
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Bioruptor Cell Lysis Bioruptor Plus
Melanoma-Associated Cancer-Testis Antigen 16 (CT16) Regulates the E...
Published: September, 2012
Abstract: Cancer-testis (CT) antigens are predominantly expressed in testis or placenta, but absent in most adult tissues. During malignant transformation CT... Read more »
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MeDIP kit
Chromatin immunoprecipitation and microarray analysis reveal that T...
Published: September, 2012
Abstract: RNA polymerase II (RNAP-II) synthesizes the m7G-capped Spliced Leader (SL) RNA and most protein-coding mRNAs in trypanosomes. RNAP-II recruitment t... Read more »
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Bioruptor Chromatin Shearing
TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors...
Published: September, 2012
Abstract: Tumor suppressor gene silencing through cytosine methylation contributes to cancer formation. Whether DNA demethylation enzymes counteract this onc... Read more »
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DNA shearing Bioruptor
Global transcriptional control by glucose and carbon regulator CcpA...
Published: September, 2012
Abstract: The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydr... Read more »
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Bioruptor Chromatin Shearing
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protecti...
Published: September, 2012
Abstract: Adaptive features of innate immunity, recently described as "trained immunity," have been documented in plants, invertebrate animals, and mice, but... Read more »
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Antibody
p53-Independent regulation of p21Waf1/Cip1 expression and senescenc...
Published: September, 2012
Abstract: p21 is a potent cyclin-dependent kinase inhibitor that plays a role in promoting G1 cell cycle arrest and cellular senescence. Consistent with this... Read more »
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Antibody
ERG and FLI1 binding sites demarcate targets for aberrant epigeneti...
Published: September, 2012
Abstract: ERG and FLI1 are closely related members of the ETS family of transcription factors and have been identified as essential factors for the function ... Read more »
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IP-Star Antibody
H4K20me1 Contributes to Downregulation of X-Linked Genes for C. ele...
Published: September, 2012
Abstract: The Caenorhabditis elegans dosage compensation complex (DCC) equalizes X-chromosome gene dosage between XO males and XX hermaphrodites by two-fold ... Read more »
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Antibody
Dynamic and Coordinated Epigenetic Regulation of Developmental Tran...
Published: September, 2012
Abstract: Heart development is exquisitely sensitive to the precise temporal regulation of thousands of genes that govern developmental decisions during diff... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A GWAS sequence variant for platelet volume marks an alternative DN...
Published: September, 2012
Abstract: We recently identified 68 genomic loci where common sequence variants are associated with platelet count and volume. Platelets are formed in the bo... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Tet2 Facilitates the Derepression of Myeloid Target Genes during CE...
Published: September, 2012
Abstract: The methylcytosine hydroxylase Tet2 has been implicated in hematopoietic differentiation and the formation of myeloid malignancies when mutated. An... Read more »
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DNA shearing Bioruptor Antibody
A Temporal Chromatin Signature in Human Embryonic Stem Cells Identi...
Published: September, 2012
Abstract: Directed differentiation of human embryonic stem cells (ESCs) into cardiovascular cells provides a model for studying molecular mechanisms of human... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Divergent antiviral effects of bioflavonoids on the hepatitis C vir...
Published: September, 2012
Abstract: We have previously demonstrated that quercetin, a bioflavonoid, blocks hepatitis C virus (HCV) proliferation by inhibiting NS5A-driven internal rib... Read more »
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Master Mix
Pesticide and Insect Repellent Mixture (Permethrin and DEET) Induce...
Published: September, 2012
Abstract: Environmental compounds are known to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a ... Read more »
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Antibody
Expression of MUC17 Is Regulated by HIF1α-Mediated Hypoxic Response...
Published: September, 2012
Abstract: MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated that the aberrant o... Read more »
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Chromatin Shearing ChIP-qPCR
Argonaute proteins couple chromatin silencing to alternative splicing.
Published: September, 2012
Abstract: Argonaute proteins play a major part in transcriptional gene silencing in many organisms, but their role in the nucleus of somatic mammalian cells ... Read more »
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Bioruptor Chromatin Shearing
Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with...
Published: September, 2012
Abstract: Background Salinomycin is a polyether ionophore antibiotic that has recently been shown to induce cell death in human cancer cells displaying mult... Read more »
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Bioruptor Cell Lysis Western Blot
A mechanistic basis for amplification differences between samples a...
Published: September, 2012
Abstract: ABSTRACT: BACKGROUND: For many analytical methods the efficiency of DNA amplification varies across the genome and between samples. The most affect... Read more »
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DNA shearing Bioruptor
A Snapshot of Histone Modifications within Transposable Elements in...
Published: September, 2012
Abstract: Transposable elements (TEs) are a major source of genetic variability in genomes, creating genetic novelty and driving genome evolution. Analysis o... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Multigenerational epigenetic adaptation of the hepatic wound-healin...
Published: September, 2012
Abstract: We investigated whether ancestral liver damage leads to heritable reprogramming of hepatic wound healing in male rats. We found that a history of l... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K27me3 (C15410069)
Mutant p53 is a transcriptional co-factor that binds to G-rich regu...
Published: September, 2012
Abstract: The molecular mechanisms underlying mutant p53 (mutp53) “gain-of-function” (GOF) are still insufficiently understood, but there is evidence that mu... Read more »
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Bioruptor Chromatin Shearing
Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor...
Published: September, 2012
Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipocyte differentiation and function. We and others have previously... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Widespread plasticity in CTCF occupancy linked to DNA methylation.
Published: September, 2012
Abstract: CTCF is a ubiquitously expressed regulator of fundamental genomic processes including transcription, intra- and interchromosomal interactions, and ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
BZLF1 Governs CpG-Methylated Chromatin of Epstein-Barr Virus Revers...
Published: September, 2012
Abstract: Epigenetic mechanisms are essential for the regulation of all genes in mammalian cells but transcriptional repression including DNA methylation are... Read more »
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DNA shearing Bioruptor
PARP activation regulates the RNA-binding protein NONO in the DNA d...
Published: August, 2012
Abstract: After the generation of DNA double-strand breaks (DSBs), poly(ADP-ribose) polymerase-1 (PARP-1) is one of the first proteins to be recruited and ac... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis
MutSβ and histone deacetylase complexes promote expansions of trinu...
Published: August, 2012
Abstract: Trinucleotide repeat (TNR) expansions cause at least 17 heritable neurological diseases, including Huntington's disease. Expansions are thought to ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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