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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

SATB1-mediated Functional Packaging of Chromatin into Loops.
Published: July, 2012
Abstract: Mammalian genomes are organized into multiple layers of higher-order chromatin structure, and in this organization chromatin looping is a striking ... Read more »
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DNA shearing Bioruptor Chromatin Shearing
An investigation of the affinities, specificity and kinetics involv...
Published: July, 2012
Abstract: Human transcription factor Yin Yang 1 (YY1) is a four-zinc-finger protein that regulates a large number of genes with different biological function... Read more »
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DNA shearing Bioruptor
Histone H2B monoubiquitination is required to reach maximal transcr...
Published: July, 2012
Abstract: Previously, we had identified HISTONE MONOUBIQUITINATION1 (HUB1) as an unconventional ubiquitin E3 ligase that was not involved in protein degradat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Lipocalin 2 (LCN2), the TNF-like receptor TWEAKR and its ligand TWE...
Published: July, 2012
Abstract: NFAT1 is a transcription factor that elicits breast carcinoma cells to become invasive, contributing thus to formation of metastasis. The molecular... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The human CST complex is a terminator of telomerase activity.
Published: July, 2012
Abstract: The lengths of human telomeres, which protect chromosome ends from degradation and end fusions, are crucial determinants of cell lifespan. During e... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Aberrant expression of IFN-γ in Th2 cells from Th2 LCR-deficient mice.
Published: July, 2012
Abstract: The Th2 locus control region (LCR) has been shown to be a crucial cis-acting element for Th2 cytokine expression and Th2 cell differentiation. To s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethy...
Published: July, 2012
Abstract: Nucleotide excision repair factors, initially characterized as part of DNA repair, have been shown to participate in the transcriptional process in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Occludin is a direct target of thyroid transcription factor-1 (TTF-...
Published: July, 2012
Abstract: The thyroid transcription factor 1 gene (TTF-1 or NKX2-1) is essential to lung development; however, it is also a critical factor in lung cancer. T... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide characterization of Foxa2 targets reveals upregulation ...
Published: July, 2012
Abstract: The transcription factors Foxa1 and Foxa2 promote the specification of midbrain dopaminergic (mDA) neurons and the floor plate. Whether their role ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) d...
Published: July, 2012
Abstract: The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Transcription termination between polo and snap, two closely spaced...
Published: July, 2012
Abstract: Transcription termination of RNA polymerase II between closely spaced genes is an important, though poorly understood, mechanism. This is true, in ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Live cell monitoring of periodic gene expression in synchronous hum...
Published: June, 2012
Abstract: We developed a system to monitor periodic luciferase activity from cell cycle-regulated promoters in synchronous cells. Reporters were driven by a ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Cohesins Repress KSHV Immediate Early Gene Transcription During Lat...
Published: June, 2012
Abstract: Chromatin-organizing factors, like CTCF and cohesins, have been implicated in the control of complex viral regulatory programs. We investigated the... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Neurog2 Simultaneously Activates and Represses Alternative Gene Exp...
Published: June, 2012
Abstract: Progenitor cells undergo a series of stable identity transitions on their way to becoming fully differentiated cells with unique identities. Each c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cdc28 kinase activity regulates the basal transcription machinery a...
Published: June, 2012
Abstract: The cyclin-dependent kinase Cdc28 is the master regulator of the cell cycle in Saccharomyces cerevisiae. Cdc28 initiates the cell cycle by activati... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Separating the wheat from the chaff: mitigating the effects of nois...
Published: June, 2012
Abstract: ABSTRACT: BACKGROUND: Through next-generation sequencing, the amount of sequence data potentially available for phylogenetic analyses has increased... Read more »
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DNA shearing Bioruptor
ZRF1 controls oncogene-induced senescence through the INK4-ARF locus.
Published: June, 2012
Abstract: The reactivation of the INK4-ARF locus, which is epigenetically repressed by Polycomb proteins in healthy cells, is a hallmark of senescence. One m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Fluorescence-based phenotypic selection allows forward genetic scre...
Published: June, 2012
Abstract: The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in app... Read more »
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DNA shearing Bioruptor
Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to pro...
Published: June, 2012
Abstract: CCAAT/enhancer-binding protein (C/EBP) β is required for both mitotic clonal expansion (MCE) and terminal adipocyte differentiation of 3T3-L1 pread... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic hydroxymethylation of deoxyribonucleic acid marks different...
Published: June, 2012
Abstract: Enhancers are developmentally controlled transcriptional regulatory regions whose activities are modulated through histone modifications or histone... Read more »
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Antibody
Genome-wide profiling in melatonin exposed human breast cancer cell...
Published: June, 2012
Abstract: Epigenetic alterations have emerged as an important mechanism involved in tumorigenesis. The epigenetic impact of DNA methylation in various types ... Read more »
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MeDIP kit
The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) ha...
Published: June, 2012
Abstract: ABSTRACT: BACKGROUND: While growing in natural environments yeasts can be affected by osmotic stress provoked by high glucose concentrations. The r... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Bovine polledness - an autosomal dominant trait with allelic hetero...
Published: June, 2012
Abstract: The persistent horns are an important trait of speciation for the family Bovidae with complex morphogenesis taking place briefly after birth. The p... Read more »
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DNA shearing Bioruptor
Topoisomerase II is required for the production of long Pol II gene...
Published: June, 2012
Abstract: The extent to which the DNA relaxation activities of eukaryotic topoisomerases (topo I and topo II) are redundant during gene transcription is uncl... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Cell Cycle Role for the Epigenetic Factor CTCF-L/BORIS.
Published: June, 2012
Abstract: CTCF is a ubiquitous epigenetic regulator that has been proposed as a master keeper of chromatin organisation. CTCF-like, or BORIS, is thought to a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF...
Published: June, 2012
Abstract: The CACCC-box binding protein Erythroid Krüppel-like Factor (EKLF/KLF1) is a master regulator that directs the expression of many important erythro... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit
Extensive promoter hypermethylation and hypomethylation is associat...
Published: June, 2012
Abstract: Dysregulated microRNA (miRNA) expression contributes to the pathogenesis of hematopoietic malignancies, including chronic lymphocytic leukemia (CLL... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star Antibody H3K4me3 (C15410003) Bioruptor Plus
Defective mitochondrial morphology and bioenergetic function in mic...
Published: June, 2012
Abstract: Formation, distribution and maintenance of functional mitochondria are achieved through dynamic processes that strictly depend on transcription of ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Targeted re-sequencing of the allohexaploid wheat exome.
Published: June, 2012
Abstract: Bread wheat, Triticum aestivum, is an allohexaploid composed of the three distinct ancestral genomes, A, B and D. The polyploid nature of the wheat... Read more »
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DNA shearing Bioruptor
GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chro...
Published: June, 2012
Abstract: JunB, an activator protein-1 (AP-1) transcription factor component, acts either as a tumor suppressor or as an oncogene depending on the cell conte... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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