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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Mus81-Mms4 function as a single heterodimer to cleave nicked interm...
Published: May, 2012
Abstract: The formation of crossovers is a fundamental genetic process. The XPF-family endonuclease, Mus81-Mms4 (Eme1), contributes significantly to crossing... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The aryl hydrocarbon receptor ligands 2,3,7,8-tetrachlorodibenzo-p-...
Published: May, 2012
Abstract: The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (ED... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide ...
Published: May, 2012
Abstract: Epigenetic regulation is an essential process for the normal functioning of genes. Therefore, targeting epigenetic dysregulation in cancer may be a... Read more »
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Antibody
Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDA...
Published: May, 2012
Abstract: Read more »
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Antibody
Epigenetic Repression of RARRES1 Is Mediated by Methylation of a Pr...
Published: May, 2012
Abstract: BACKGROUND: The cis-acting promoter element responsible for epigenetic silencing of retinoic acid receptor responder 1 (RARRES1) by methylation is ... Read more »
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Antibody
Functional Genomic Methods to Study Estrogen Receptor Activity.
Published: May, 2012
Abstract: Estrogen Receptor (ER) is a nuclear receptor that mediates the actions of estrogen and tamoxifen. ER is expressed in a major fraction of human brea... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Dynamics of enhancer chromatin signatures mark the transition from ...
Published: May, 2012
Abstract: The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Evolution of Burkholderia pseudomallei in Recurrent Melioidosis.
Published: May, 2012
Abstract: Burkholderia pseudomallei, the etiologic agent of human melioidosis, is capable of causing severe acute infection with overwhelming septicemia lead... Read more »
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DNA shearing Bioruptor
The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulate...
Published: May, 2012
Abstract: Lineage commitment studies in mammary glands have focused on identifying cell populations that display stem or progenitor properties. However, the ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
The angiogenesis suppressor gene AKAP12 is under the epigenetic con...
Published: May, 2012
Abstract: Histone deacetylases (HDACs) are a family of 18 enzymes that deacetylate lysine residues of both histone and nonhistone proteins and to a large ext... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
HIF1A induces expression of the WASF3 metastasis-associated gene un...
Published: May, 2012
Abstract: The WASF3 (WAVE3) gene is an important mediator of cell motility, invasion and metastasis and is expressed at high levels in some advanced stage tu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The linker histone plays a dual role during gametogenesis in S. cer...
Published: May, 2012
Abstract: The differentiation of gametes involves dramatic changes to chromatin, affecting transcription, meiosis, and cell morphology. Sporulation in S. cer... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis ChIP-seq Western Blot
BIM promoter directly targeted by EBNA3C in polycomb-mediated repre...
Published: May, 2012
Abstract: Detailed analyses of the chromatin around the BIM promoter has revealed that latent Epstein-Barr virus (EBV) triggers the recruitment of polycomb r... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Glucose-Dependent Regulation of NR2F2 Promoter and Influence of SNP...
Published: May, 2012
Abstract: BACKGROUND: The Nuclear Receptor 2F2 (NR2F2/COUP-TFII) heterozygous knockout mice display low basal insulinemia and enhanced insulin sensitivity. W... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Integrative genomics identifies the corepressor SMRT as a gatekeepe...
Published: May, 2012
Abstract: The molecular role of corepressors is poorly understood. Here, we studied the transcriptional function of the corepressor SMRT during terminal adip... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Ep...
Published: May, 2012
Abstract: Repetitive sequences account for more than 50% of the human genome. Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The histone demethylase Kdm3a is essential to progression through d...
Published: May, 2012
Abstract: Histone demethylation has important roles in regulating gene expression and forms part of the epigenetic memory system that regulates cell fate and... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
DNA methylation in an intron of the IBM1 histone demethylase gene s...
Published: May, 2012
Abstract: The stability of epigenetic patterns is critical for genome integrity and gene expression. This highly coordinated process involves interrelated po... Read more »
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Antibody LowCell ChIP kit
Hsp90 globally targets paused RNA polymerase to regulate gene expre...
Published: May, 2012
Abstract: The molecular chaperone Heat shock protein 90 (Hsp90) promotes the maturation of several important proteins and plays a key role in development, ca... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide analysis of p63 binding sites identifies AP-2 factors a...
Published: May, 2012
Abstract: The p63 transcription factor (TP63) is critical in development, growth and differentiation of stratifying epithelia. This is highlighted by the sev... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq
RBE controls microRNA164 expression to effect floral organogenesis.
Published: May, 2012
Abstract: The establishment and maintenance of organ boundaries are vital for animal and plant development. In the Arabidopsis flower, three microRNA164 gene... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Differential Modulation of the Oligodendrocyte Transcriptome by Son...
Published: May, 2012
Abstract: Differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes is regulated by the interplay between extrinsic signals and... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Flk1-cre Mediated Deletion of ETV2 Defines Its Narrow Temporal ...
Published: May, 2012
Abstract: During embryonic development, the emergence of hematopoiesis and vasculogenesis is tightly associated, with many transcription factors implicated i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
High throughput automated chromatin immunoprecipitation as a platfo...
Published: May, 2012
Abstract: Chromatin immunoprecipitation (ChIP) is an assay for interrogating protein-DNA interactions that is increasingly being used for drug target discove... Read more »
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Bioruptor Chromatin Shearing
Hydroxylation of 5-methylcytosine by TET2 maintains the active stat...
Published: May, 2012
Abstract: Differentiation is accompanied by extensive epigenomic reprogramming, leading to the repression of stemness factors and the transcriptional mainten... Read more »
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DNA shearing Bioruptor
Genome-wide search reveals the existence of a limited number of thy...
Published: May, 2012
Abstract: Thyroid hormone (T3) has a major influence on cerebellum post-natal development. The major phenotypic landmark of exposure to low levels of T3 duri... Read more »
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Bioruptor Chromatin Shearing
piRNA-mediated transgenerational inheritance of an acquired trait.
Published: May, 2012
Abstract: The maintenance of genome integrity is an essential trait to the successful transmission of genetic information. In animal germ cells, piRNAs guide... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Environmentally induced epigenetic transgenerational inheritance of...
Published: May, 2012
Abstract: The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was inves... Read more »
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Antibody
Disruption of RAB40AL function leads to Martin-Probst syndrome, a r...
Published: May, 2012
Abstract: Background and aim Martin-Probst syndrome (MPS) is a rare X-linked disorder characterised by deafness, cognitive impairment, short stature and dist... Read more »
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DNA shearing Bioruptor
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors...
Published: May, 2012
Abstract: Increasing evidence suggests that chromatin modifications have important roles in modulating constitutive or alternative splicing. Here we demonstr... Read more »
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Bioruptor Chromatin Shearing

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