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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the P...
Published: March, 2012
Abstract: BACKGROUND: Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation is one of epigenetic mech... Read more »
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DNA shearing Bioruptor
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights...
Published: March, 2012
Abstract: Synovial sarcoma is a translocation-associated sarcoma where the underlying chromosomal event generates SS18-SSX fusion transcripts. In vitro and i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis.
Published: March, 2012
Abstract: The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regu... Read more »
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DNA shearing Bioruptor
Mammalian HCA66 protein is required for both ribosome synthesis and...
Published: March, 2012
Abstract: Ribosome production, one of the most energy-consuming biosynthetic activities in living cells, is adjusted to growth conditions and coordinated wit... Read more »
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Bioruptor Cell Lysis Western Blot
Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidops...
Published: March, 2012
Abstract: Nucleosomes package eukaryotic DNA and are composed of four different histone proteins, designated H3, H4, H2A, and H2B. Histone H3 has two main va... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
DLK2 is a transcriptional target of KLF4 in the early stages of adi...
Published: March, 2012
Abstract: The epidermal growth factor-like protein DLK2, highly homologous to DLK1, has been identified as a modulator of adipogenesis in vitro. Knocking dow... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An epigenetic mechanism for high, synergistic expression of indolea...
Published: March, 2012
Abstract: IDO1 can be induced by interferon gamma (IFN-γ) in multiple cell types. We have earlier described that the DNA methyltransferase inhibitor zebulari... Read more »
Proteome analysis of Acetobacter pasteurianus during acetic acid fe...
Published: March, 2012
Abstract: Acetic acid bacteria (AAB) are Gram-negative, strictly aerobic microorganisms that show a unique resistance to ethanol (EtOH) and acetic acid (AcH)... Read more »
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Bioruptor Cell Lysis
Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with...
Published: March, 2012
Abstract: Mutations of the Wnt5a gene, encoding a ligand of the non-canonical Wnt pathway, and the Ror2 gene, encoding its receptor, have been found in patie... Read more »
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LowCell ChIP kit
Identification and characterization of ToRC, a novel ISWI-containin...
Published: March, 2012
Abstract: SNF2-like motor proteins, such as ISWI, cooperate with histone chaperones in the assembly and remodeling of chromatin. Here we describe a novel, ev... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide evaluation of histone methylation changes associated wi...
Published: March, 2012
Abstract: Leaf senescence is the orderly dismantling of older tissue that allows recycling of nutrients to developing portions of the plant and is accompanie... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Resveratrol Inhibits KSHV Reactivation by Lowering the Levels of Ce...
Published: March, 2012
Abstract: In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Toxoplasma gondii Chromodomain Protein 1 Binds to Heterochromatin a...
Published: March, 2012
Abstract: Background Apicomplexan parasites are responsible for some of the most deadly parasitic diseases afflicting humans, including malaria and toxoplas... Read more »
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites...
Published: March, 2012
Abstract: Polycomb group (PcG) proteins are involved in epigenetic silencing where they function as major determinants of cell identity, stem cell pluripoten... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Methylome analysis using MeDIP-seq with low DNA concentrations.
Published: March, 2012
Abstract: DNA methylation is an epigenetic mark that has a crucial role in many biological processes. To understand the functional consequences of DNA methyl... Read more »
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DNA shearing Bioruptor IP-Star MagMeDIP kit
Integrated epigenome profiling of repressive histone modifications,...
Published: March, 2012
Abstract: Epigenetic regulation of gene expression is commonly altered in human cancer. We have observed alterations of DNA methylation and microRNA expressi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Estrogen receptor alpha mediates progestin-induced mammary tumor gr...
Published: March, 2012
Abstract: Synthetic progesterone used in contraception drugs (progestins) can promote breast cancer growth but the mechanisms involved are unknown. Moreover,... Read more »
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HighCell ChIP kit
Chromatin-modifying enzymes as modulators of reprogramming.
Published: March, 2012
Abstract: Generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic remodelling. Whereas several proteins... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates...
Published: March, 2012
Abstract: The generation of induced pluripotent stem cells (iPSCs) often results in aberrant epigenetic silencing of the imprinted Dlk1-Dio3 gene cluster, co... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mutually exclusive binding of telomerase RNA and DNA by ku alters t...
Published: March, 2012
Abstract: In Saccharomyces cerevisiae, the Ku heterodimer contributes to telomere maintenance as a component of telomeric chromatin and as an accessory subun... Read more »
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Bioruptor Cell Lysis
Mapping and Functional Characterisation of a CTCF-Dependent Insulat...
Published: March, 2012
Abstract: The Scl gene encodes a transcription factor essential for haematopoietic development. Scl transcription is regulated by a panel of cis-elements spr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RYBP Represses Endogenous Retroviruses and Preimplantation- and Ger...
Published: March, 2012
Abstract: Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function. RYBP binds Polycomb H2A monoubiquitin... Read more »
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Bioruptor Chromatin Shearing
Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating...
Published: March, 2012
Abstract: The Mixl1 homeodomain protein plays a key role in mesendoderm patterning during embryogenesis, but its target genes remain to be identified. We com... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The rs3743205 SNP Is Important for the Regulation of the Dyslexia C...
Published: March, 2012
Abstract: Estrogen is involved in numerous physiological processes such as growth, differentiation, and function of the male and female reproductive tissues.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
EZH2 couples pancreatic regeneration to neoplastic progression.
Published: March, 2012
Abstract: Although the polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) is well recognized for its role as a key regulator of cell differentiation, ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
High Resolution Genetic Mapping by Genome Sequencing Reveals Genome...
Published: March, 2012
Abstract: Not Available Read more »
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DNA shearing Bioruptor Bioruptor Plus
Widespread site-dependent buffering of human regulatory polymorphism.
Published: March, 2012
Abstract: The average individual is expected to harbor thousands of variants within non-coding genomic regions involved in gene regulation. However, it is cu... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Small-molecule-induced DNA damage identifies alternative DNA struct...
Published: March, 2012
Abstract: Guanine-rich DNA sequences that can adopt non-Watson-Crick structures in vitro are prevalent in the human genome. Whether such structures normally ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal t...
Published: March, 2012
Abstract: Pancreas development is initiated by the specification and expansion of a small group of endodermal cells. Several transcription factors are crucia... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the ...
Published: March, 2012
Abstract: To elucidate the molecular mechanism underlying the endochondral ossification process during the skeletal growth and osteoarthritis (OA) developmen... Read more »
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Antibody

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