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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-...
Published: January, 2012
Abstract: Bmi1 is a key stem cell regulatory gene implicated in the pathogenesis of many aggressive cancers, including medulloblastoma. Overexpression of Bmi... Read more »
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LowCell ChIP kit
A novel retinoblastoma therapy from genomic and epigenetic analyses
Published: January, 2012
Abstract: Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very qui... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genetic inactivation of the polycomb repressive complex 2 in T cell...
Published: January, 2012
Abstract: T cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling. In t... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Activating transcription factor 4-dependent induction of FGF21 duri...
Published: January, 2012
Abstract: Nutrient deprivation or starvation frequently correlates with amino acid limitation. Amino acid starvation initiates a signal transduction cascade ... Read more »
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Chromatin Shearing ChIP-qPCR Bioruptor Plus
Nonoverlapping functions of the Polycomb group Cbx family of protei...
Published: January, 2012
Abstract: Polycomb group proteins are essential regulators of cell fate decisions during embryogenesis. In mammals, at least five different Cbx proteins (Cbx... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RAD tag sequencing as a source of SNP markers in Cynara cardunculus L.
Published: January, 2012
Abstract: ABSTRACT: BACKGROUND: The globe artichoke (Cynara cardunculus L. var. scolymus) genome is relatively poorly explored, especially compared to those... Read more »
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DNA shearing Bioruptor
Epigenetic control of somatostatin and cortistatin expression by β ...
Published: January, 2012
Abstract: β Amyloid, present in senile plaques, has been related largely to neuronal loss in the brain of patients with Alzheimer's disease. However, how neu... Read more »
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LowCell ChIP kit
Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA...
Published: January, 2012
Abstract: Aberrant neocortical DNA methylation has been suggested to be a pathophysiological contributor to psychotic disorders. Recently, a growth arrest an... Read more »
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Antibody 5mC (C15200081)
dSet1 is the main H3K4 di- and tri-methyltransferase throughout Dro...
Published: January, 2012
Abstract: In eukaryotes, the post-translational addition of methyl groups to histone H3 lysine 4 (H3K4) plays key roles in maintenance and establishment of a... Read more »
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Bioruptor
The prosensory function of sox2 in the chicken inner ear relies on ...
Published: January, 2012
Abstract: The proneural gene Atoh1 is crucial for the development of inner ear hair cells and it requires the function of the transcription factor Sox2 throu... Read more »
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Chromatin Shearing ChIP-qPCR
Novel transcriptional targets of the SRY-HMG box transcription fact...
Published: January, 2012
Abstract: The HMG box transcription factor SOX4 involved in neuronal development is amplified and overexpressed in a subset of lung cancers, suggesting that ... Read more »
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Antibody
The cytokine temporal profile in rat cortex after controlled cortic...
Published: January, 2012
Abstract: Cerebral inflammatory responses may initiate secondary cascades following traumatic brain injury (TBI). Changes in the expression of both cytokines... Read more »
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Bioruptor Tissue Homogenization
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels im...
Published: December, 2011
Abstract: The TET family of FE(II) and 2-oxoglutarate-dependent enzymes (Tet1/2/3) promote DNA demethylation by converting 5-methylcytosine to 5-hydroxymethy... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
High-Mobility Group A1 Protein: A New Coregulator of Peroxisome Pro...
Published: December, 2011
Abstract: Rationale:The nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) is an important regulator of gene transcription in vascular cel... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
Genotoxic effects of silver nanoparticles stimulated by oxidative s...
Published: December, 2011
Abstract: Many classes of silver nanoparticles (Ag-NPs) have been synthesized and widely applied, but the genotoxicity of Ag-NPs and the factors leading to g... Read more »
The little elongation complex regulates small nuclear RNA transcrip...
Published: December, 2011
Abstract: Eleven-nineteen lysine-rich leukemia (ELL) participates in the super elongation complex (SEC) with the RNA polymerase II (Pol II) CTD kinase P-TEFb... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Adaptation to P element transposon invasion in Drosophila melanogas...
Published: December, 2011
Abstract: Transposons evolve rapidly and can mobilize and trigger genetic instability. Piwi-interacting RNAs (piRNAs) silence these genome pathogens, but it ... Read more »
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DNA shearing Bioruptor
Caenorhabditis elegans Heterochromatin Protein 1 (HPL-2) links deve...
Published: December, 2011
Abstract: ABSTRACT: BACKGROUND: Heterochromatin protein 1 (HP1) family proteins have a well-characterized role in heterochromatin packaging and gene regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of a proximal Sp1 response element in the mouse Dl...
Published: December, 2011
Abstract: ABSTRACT: BACKGROUND: DLK2 is an EGF-like membrane protein, closely related to DLK1, which is involved in adipogenesis. Both proteins interact wit... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A small molecule differentiation inducer increases insulin producti...
Published: December, 2011
Abstract: New drugs for preserving and restoring pancreatic β-cell function are critically needed for the worldwide epidemic of type 2 diabetes and the cure ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Second order regulator Collier directly controls intercalary-specif...
Published: December, 2011
Abstract: In Drosophila, trunk metamerization is established by a cascade of segmentation gene activities: the gap genes, the pair rule genes, and the segmen... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of cell growth by Notch signaling and its differential r...
Published: December, 2011
Abstract: Cancer stem cells (CSCs) are postulated to be a small subset of tumor cells with tumor-initiating ability that shares features with normal tissue-s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
cAMP response element-binding protein is a primary hub of activity-...
Published: December, 2011
Abstract: Long-lasting forms of neuronal plasticity require de novo gene expression, but relatively little is known about the events that occur genome-wide i... Read more »
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Bioruptor Cell Lysis Western Blot
Prepatterning of developmental gene expression by modified histones...
Published: December, 2011
Abstract: A hallmark of anamniote vertebrate development is a window of embryonic transcription-independent cell divisions before onset of zygotic genome act... Read more »
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Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)
The Chromatin Binding Protein HMGN1 Regulates the Expression of Met...
Published: December, 2011
Abstract: High Mobility Group N1 protein (HMGN1), a nucleosomal binding protein that affects the structure and function of chromatin, is encoded by a gene lo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals ...
Published: December, 2011
Abstract: The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Bio-CAP: a versatile and highly sensitive technique to purify and c...
Published: December, 2011
Abstract: Across vertebrate genomes methylation of cytosine residues within the context of CpG dinucleotides is a pervasive epigenetic mark that can impact g... Read more »
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DNA shearing Bioruptor
Tracheobronchial transplantation with a stem-cell-seeded bioartific...
Published: December, 2011
Abstract: BACKGROUND: Tracheal tumours can be surgically resected but most are an inoperable size at the time of diagnosis; therefore, new therapeutic optio... Read more »
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Antibody LowCell ChIP kit
Comprehensive genome-wide protein-DNA interactions detected at sing...
Published: December, 2011
Abstract: Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins bind throughout a genome. However, DNA contamination and DNA ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A distinct mechanism for coactivator versus corepressor function by...
Published: December, 2011
Abstract: Histone methyltransferase G9a has been understood primarily as a corepressor of gene expression, but we showed previously that G9a positively regul... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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