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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The draft genome and transcriptome of Cannabis sativa.
Published: October, 2011
Abstract: ABSTRACT: BACKGROUND: Cannabis sativa has been cultivated throughout human history as a source of fiber, oil and food, and for its medicinal and i... Read more »
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DNA shearing Bioruptor
Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for...
Published: October, 2011
Abstract: Master regulator protein p53, popularly known as the "guardian of genome" is the hub for regulation of diverse cellular pathways. Depending on the ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The oxidized thiol proteome in fission yeast--optimization of an IC...
Published: October, 2011
Abstract: Major intracellular disulfide formation is prevented in the cytosol by potent reducing systems. However, protein thiols can be oxidized as a conseq... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
Androgen receptor and nutrient signaling pathways coordinate the de...
Published: October, 2011
Abstract: L-type amino acid transporters such as LAT1 and LAT3 mediate the uptake of essential amino acids. Here we report that prostate cancer cells coordin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
R432 is a key residue for the multiple functions of Ndt80p in Candi...
Published: October, 2011
Abstract: Ndt80p is an important transcription modulator to various stress-response genes in Candida albicans, the most common human fungal pathogen in syste... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Maternal cannabis use alters ventral striatal dopamine D2 gene regu...
Published: October, 2011
Abstract: BACKGROUND: Prenatal cannabis exposure has been linked to addiction vulnerability, but the neurobiology underlying this risk is unknown. METHODS: S... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional signatures of regulatory and toxic responses to ben...
Published: October, 2011
Abstract: ABSTRACT: BACKGROUND: Small molecule ligands often have multiple effects on the transcriptional program of a cell: they trigger a receptor specifi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Mutations in CSTA, encoding Cystatin A, underlie exfoliative ichthy...
Published: October, 2011
Abstract: Autosomal-recessive exfoliative ichthyosis presents shortly after birth as dry, scaly skin over most of the body with coarse peeling of nonerythema... Read more »
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DNA shearing Bioruptor
CTCF-promoted RNA polymerase II pausing links DNA methylation to sp...
Published: October, 2011
Abstract: Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is poorly understood.... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR Antibody
The human histone H3 complement anno 2011.
Published: October, 2011
Abstract: Histones are highly basic, relatively small proteins that complex with DNA to form higher order structures that underlie chromosome topology. Of th... Read more »
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Antibody
NF-κB controls energy homeostasis and metabolic adaptation by upreg...
Published: October, 2011
Abstract: Cell proliferation is a metabolically demanding process. It requires active reprogramming of cellular bioenergetic pathways towards glucose metabol... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Size-dependent cytotoxicity of amorphous silica nanoparticles in hu...
Published: October, 2011
Abstract: The purpose of this study is to compare the potential cytotoxicity induced by amorphous silica particles with different sizes. The effects of one f... Read more »
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Bioruptor
Specific regulatory motifs predict glucocorticoid responsiveness of...
Published: October, 2011
Abstract: The glucocorticoid receptor (GR) is an ubiquitously expressed ligand-activated transcription factor that mediates effects of cortisol in relation t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Separation-of-function mutation in HPC2, a member of the HIR comple...
Published: October, 2011
Abstract: The HIR complex, which is comprised of the four proteins Hir1, Hir2, Hir3 and Hpc2, was first characterized as a repressor of three of the four his... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Spt6 is required for heterochromatic silencing in the fission yeast...
Published: October, 2011
Abstract: Spt6 is a conserved factor, critically required for several transcription- and chromatin-related processes. We now show that Spt6 and its binding p... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNA methylation profiles of human active and inactive X chromosomes.
Published: October, 2011
Abstract: X-chromosome inactivation (XCI) is a dosage compensation mechanism that silences the majority of genes on one X chromosome in each female cell. To ... Read more »
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Antibody
Large-scale methylation domains mark a functional subset of neurona...
Published: October, 2011
Abstract: DNA methylation is essential for embryonic and neuronal differentiation, but the function of most genomic DNA methylation marks is poorly understoo... Read more »
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DNA shearing Bioruptor
Targeted bisulfite sequencing by solution hybrid selection and mass...
Published: October, 2011
Abstract: We applied a solution hybrid selection approach to the enrichment of CpG islands (CGIs) and promoter sequences from the human genome for targeted h... Read more »
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DNA shearing Bioruptor
Translocation-capture sequencing reveals the extent and nature of c...
Published: September, 2011
Abstract: Chromosomal rearrangements, including translocations, require formation and joining of DNA double strand breaks (DSBs). These events disrupt the in... Read more »
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DNA shearing Bioruptor
A Protein Epitope Signature Tag (PrEST) Library Allows SILAC-based ...
Published: September, 2011
Abstract: Mass spectrometry-based proteomics increasingly relies on relative or absolute quantification. In relative quantification, stable isotope based met... Read more »
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Bioruptor Cell Lysis
DNA-end capping by the budding yeast transcription factor and subte...
Published: September, 2011
Abstract: Telomere repeats in budding yeast are maintained at a constant average length and protected (‘capped’), in part, by mechanisms involving the TG13 ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone tail acetylation in brain occurs in an unpredictable fashio...
Published: September, 2011
Abstract: Histone acetylation plays a role in the regulation of gene transcription. Yet it is not known whether post-mortem brain tissue is suitable for the ... Read more »
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Antibody LowCell ChIP kit
An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a...
Published: September, 2011
Abstract: An evolutionarily conserved subcircuit (kernel) dedicated to a specific developmental function is found at the top of the gene regulatory networks ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Studying RNA–Protein Interactions In Vivo By RNA Immunoprecipitation
Published: September, 2011
Abstract: The crucial roles played by RNA-binding proteins in all aspects of RNA metabolism, particularly in the regulation of transcription, have become inc... Read more »
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Bioruptor
Reciprocal repression between Sox3 and snail transcription factors ...
Published: September, 2011
Abstract: In developing amniote embryos, the first epithelial-to-mesenchymal transition (EMT) occurs at gastrulation, when a subset of epiblast cells moves t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Glutathione-S-transferase pi 1(GSTP1) gene silencing in prostate ca...
Published: September, 2011
Abstract: Gene silencing by epigenetic mechanisms is frequent in prostate cancer (PCA). The link between DNA hypermethylation and histone modifications is no... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
BRCA1 tumour suppression occurs via heterochromatin-mediated silenc...
Published: September, 2011
Abstract: Mutations in the tumour suppressor gene BRCA1 lead to breast and/or ovarian cancer. Here we show that loss of Brca1 in mice results in transcriptio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rapid, massively parallel single-cell drug response measurements vi...
Published: September, 2011
Abstract: A central question in cancer therapy is how individual cells within a population of tumor cells respond to drugs designed to arrest their growth. H... Read more »
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Master Mix
Silencing of Kruppel-like factor 2 by the histone methyltransferase...
Published: September, 2011
Abstract: The Kruppel-like factor (KLF) proteins are multitasked transcriptional regulators with an expanding tumor suppressor function. KLF2 is one of the p... Read more »
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Antibody H3K27me3 (C15410069)
Interaction of Arabidopsis DET1 with CCA1 and LHY in mediating tran...
Published: September, 2011
Abstract: The COP10-DET1-DDB1 (CDD) complex is an evolutionarily conserved protein complex discovered for its role in the repression of photomorphogenesis in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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