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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Epigenetic switch involved in activation of pioneer factor FOXA1-de...
Published: April, 2011
Abstract: Transcription factors (TFs) bind specifically to discrete regions of mammalian genomes called cis-regulatory elements. Among those are enhancers, w... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR Antibody
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell m...
Published: April, 2011
Abstract: Schwann cell myelination is tightly regulated by timely expression of key transcriptional regulators that respond to specific environmental cues, b... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Bin3 RNA methyltransferase is required for repression of caudal...
Published: April, 2011
Abstract: Bin3 was first identified as a Bicoid-interacting protein in a yeast two-hybrid screen. In human cells, a Bin3 ortholog (BCDIN3) methylates the 5' ... Read more »
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Bioruptor
Psm3 acetylation on conserved lysine residues is dispensable for vi...
Published: April, 2011
Abstract: In budding yeast and humans, cohesion establishment during S phase requires the acetyltransferase Eco1/Esco1-2, which acetylates the cohesin subuni... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveal...
Published: April, 2011
Abstract: Recent studies have demonstrated that the Ten-eleven translocation (Tet) family proteins can enzymatically convert 5-methylcytosine (5mC) to 5-hydr... Read more »
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Antibody
Heterochromatin formation in bistable chromatin domains controls th...
Published: April, 2011
Abstract: Clonally variant gene expression is a common survival strategy used by many pathogens, including the malaria parasite Plasmodium falciparum. Among ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Recombineering, transfection, Western, IP and ChIP methods for prot...
Published: April, 2011
Abstract: Protein tagging offers many advantages for proteomic and regulomic research. Ideally, protein tagging is equivalent to having a high affinity antib... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Western Blot Antibody
Epigenetic Regulation of Glucose Transporters in Non-Small Cell Lun...
Published: March, 2011
Abstract: Due to their inherently hypoxic environment, cancer cells often resort to glycolysis, or the anaerobic breakdown of glucose to form ATP to provide ... Read more »
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Antibody H3K4me3 (C15410003)
Comprehensive analysis of the chromatin landscape in Drosophila mel...
Published: March, 2011
Abstract: Chromatin is composed of DNA and a variety of modified histones and non-histone proteins, which have an impact on cell differentiation, gene regula... Read more »
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Bioruptor Chromatin Shearing
Biparental inheritance of chromosomal abnormalities in male twins w...
Published: March, 2011
Abstract: In a monozygotic twin couple with mental retardation (MR), we identified a maternally inherited inversion and a paternally inherited translocation:... Read more »
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DNA shearing Bioruptor
Direct recruitment of ERK cascade components to inducible genes is ...
Published: March, 2011
Abstract: Components of the ERK cascade are recruited to genes, but it remains unknown how they are regulated at these sites. The RNA-binding protein heterog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of the PMP22 gene through an intronic enhancer.
Published: March, 2011
Abstract: Successful myelination of the peripheral nervous system depends upon induction of major protein components of myelin, such as peripheral myelin pro... Read more »
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Bioruptor Chromatin Shearing
The multifunctional Ccr4-Not complex directly promotes transcriptio...
Published: March, 2011
Abstract: The Ccr4-Not complex has been implicated in the control of multiple steps of mRNA metabolism; however, its functions in transcription remain ambigu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
5-Hydroxymethylcytosine in the mammalian zygote is linked with epig...
Published: March, 2011
Abstract: The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a totipotent developmental potential. A major initial event in th... Read more »
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Antibody
Role for miR-204 in human pulmonary arterial hypertension.
Published: March, 2011
Abstract: Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PAS... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cutting edge: persistently open chromatin at effector gene loci in ...
Published: March, 2011
Abstract: Memory CD8(+) T cells are characterized by more rapid and robust effector function upon infection compared with naive T cells, but factors governin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alte...
Published: March, 2011
Abstract: Pre-messenger RNAs (pre-mRNAs) maturation is initiated cotranscriptionally. It is therefore conceivable that chromatin-borne information participat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ah receptor antagonism inhibits constitutive and cytokine inducible...
Published: March, 2011
Abstract: There is increasing evidence that the aryl hydrocarbon receptor (AHR) plays a role in tumor progression through numerous mechanisms. We have previo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of ...
Published: March, 2011
Abstract: The regulation of neutrophil lifespan by induction of apoptosis is critical for maintaining an effective host response and preventing excessive inf... Read more »
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Bioruptor Cell Lysis
SNP discovery in black cottonwood (Populus trichocarpa) by populati...
Published: March, 2011
Abstract: The western black cottonwood (Populus trichocarpa) was the first tree to have its genome fully sequenced and has emerged as the model species for t... Read more »
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DNA shearing Bioruptor
EpiChIP: gene-by-gene quantification of epigenetic modification lev...
Published: March, 2011
Abstract: The combination of chromatin immunoprecipitation with next-generation sequencing technology (ChIP-seq) is a powerful and increasingly popular metho... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
DNA methyltransferase 1, cytosine methylation, and cytosine hydroxy...
Published: March, 2011
Abstract: Mitochondrial DNA (mtDNA) has been reported to contain 5-methylcytosine (5mC) at CpG dinucleotides, as in the nuclear genome, but neither the mecha... Read more »
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DNA shearing Bioruptor
High-resolution genome-wide in vivo footprinting of diverse transcr...
Published: March, 2011
Abstract: Regulation of gene transcription in diverse cell types is determined largely by varied sets of cis-elements where transcription factors bind. Here ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Synergism between DNA methylation and macroH2A1 occupancy in epigen...
Published: March, 2011
Abstract: Promoter hypermethylation and heterochromatinization is a frequent event leading to gene inactivation and tumorigenesis. At the molecular level, in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Role for cohesin in the formation of a heterochromatic domain at fi...
Published: March, 2011
Abstract: Increasing evidence implicates cohesin in the control of gene expression. Here we report the first analysis of cohesin-dependent gene regulation in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen receptor α-mediated transcription induces cell cycle-depen...
Published: March, 2011
Abstract: Prolonged exposure to estrogen increases breast cancer risk. Estrogen is known to induce chromosomal aberrations, yet the mechanisms by which estro... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A critical role for the protein phosphatase 2A B'α regulatory subun...
Published: March, 2011
Abstract: Sphingosine kinase 1 (SK1) is an important regulator of cellular signalling that has gained recent attention as a potential target for anti-cancer ... Read more »
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Bioruptor Cell Lysis
Involvement of placental growth factor in Wallerian degeneration.
Published: March, 2011
Abstract: Wallerian degeneration (WD) is an inflammatory process of nerve degeneration, which occurs more rapidly in the peripheral nervous system compared w... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Aurora kinase B activity is modulated by thyroid hormone during tra...
Published: March, 2011
Abstract: Covalent histone modifications clearly play an essential role in ligand-dependent transcriptional regulation by nuclear receptors. One of the predo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
H3 lysine 4 is acetylated at active gene promoters and is regulated...
Published: March, 2011
Abstract: Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification whose role in the regulation of gene expression has been ex... Read more »
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Bioruptor Chromatin Shearing

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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