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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Molecular and evolutionary characteristics of the fraction of human...
Published: January, 2010
Abstract: BACKGROUND: The mode of evolution of the highly homogeneous Higher-Order-Repeat-containing alpha satellite arrays is still subject to discussion. T... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis ...
Published: January, 2010
Abstract: Global DNA hypomethylation is a hallmark of cancer cells, but its molecular mechanisms have not been elucidated. Here, we show that the disruption ... Read more »
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MeDIP kit
Impact of DNA demethylation of the G0S2 gene on the transcription o...
Published: December, 2009
Abstract: We recently identified that DNA methylation of the G0S2 gene was significantly more frequent in squamous lung cancer than in non-squamous lung canc... Read more »
Cytotoxic effect and apoptosis induction by silver nanoparticles in...
Published: December, 2009
Abstract: Nanosilver has well-known antibacterial properties, and is widely used in daily life as various medical and general products. In comparison with si... Read more »
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Bioruptor
Muscle inactivation of mTOR causes metabolic and dystrophin defects...
Published: December, 2009
Abstract: Mammalian target of rapamycin (mTOR) is a key regulator of cell growth that associates with raptor and rictor to form the mTOR complex 1 (mTORC1) a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain emb...
Published: December, 2009
Abstract: Embryonic stem cell (ESC) pluripotency is dependent on an intrinsic gene regulatory network centered on Oct4. Propagation of the pluripotent state ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dissection of Rad9 BRCT domain function in the mitotic checkpoint r...
Published: December, 2009
Abstract: In Saccharomyces cerevisiae, destabilizing telomeres, via inactivation of telomeric repeat binding factor Cdc13, induces a cell cycle checkpoint th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone H1 binding is inhibited by histone variant H3.3
Published: December, 2009
Abstract: Linker histones are involved in the formation of higher-order chromatin structure and the regulation of specific genes, yet it remains unclear what... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cag3 is a novel essential component of the Helicobacter pylori Cag ...
Published: December, 2009
Abstract: Helicobacter pylori strains harboring the cag pathogenicity island (PAI) have been associated with more severe gastric disease in infected humans. ... Read more »
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Bioruptor Cell Lysis
DNA methylation programming and reprogramming in primate embryonic ...
Published: December, 2009
Abstract: DNA methylation is an important epigenetic mechanism, affecting normal development and playing a key role in reprogramming epigenomes during stem c... Read more »
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Antibody
Simultaneous quantitative analysis of N-acylethanolamides in clinic...
Published: December, 2009
Abstract: A simple and rapid analytical method is described for the simultaneous quantitative analysis of three different N-acylethanolamides in human biolog... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
CpG-island promoters drive transcription of human telomeres.
Published: December, 2009
Abstract: The longstanding dogma that telomeres, the heterochromatic extremities of linear eukaryotic chromosomes, are transcriptionally silent was overturne... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic DNA methylation programs persistent adverse effects of earl...
Published: December, 2009
Abstract: Adverse early life events can induce long-lasting changes in physiology and behavior. We found that early-life stress (ELS) in mice caused enduring... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Set2-dependent K36 methylation is regulated by novel intratail inte...
Published: December, 2009
Abstract: Posttranslational modifications to histones have been studied extensively, but the requirement for the residues within the tails for different stag... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ZBED6, a novel transcription factor derived from a domesticated DNA...
Published: December, 2009
Abstract: A single nucleotide substitution in intron 3 of IGF2 in pigs abrogates a binding site for a repressor and leads to a 3-fold up-regulation of IGF2 i... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Discovering hematopoietic mechanisms through genome-wide analysis o...
Published: November, 2009
Abstract: GATA factors interact with simple DNA motifs (WGATAR) to regulate critical processes, including hematopoiesis, but very few WGATAR motifs are occup... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
An oestrogen-receptor-alpha-bound human chromatin interactome.
Published: November, 2009
Abstract: Genomes are organized into high-level three-dimensional structures, and DNA elements separated by long genomic distances can in principle interact ... Read more »
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Antibody
The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of e...
Published: November, 2009
Abstract: The size of the mammalian body is determined by genetic and environmental factors differentially modulating pre- and postnatal growth. We now repor... Read more »
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LowCell ChIP kit
Frequent long-range epigenetic silencing of protocadherin gene clus...
Published: November, 2009
Abstract: Wilms' tumour (WT) is a pediatric tumor of the kidney that arises via failure of the fetal developmental program. The absence of identifiable mutat... Read more »
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DNA shearing Bioruptor
Global analysis of H3K4 methylation defines MLL family member targe...
Published: November, 2009
Abstract: A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) at promoter regions. Set1/COMPASS was the f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The presence of RNA polymerase II, active or stalled, predicts epig...
Published: November, 2009
Abstract: Instructive mechanisms are present for induction of DNA methylation, as shown by methylation of specific CpG islands (CGIs) by specific inducers an... Read more »
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Antibody
Zinc finger transcription factor ecotropic viral integration site 1...
Published: November, 2009
Abstract: Ecotropic viral integration site 1 (EVI1) plays important roles in leukaemia and development, and its expression is temporally and spatially highly... Read more »
Antiangiogenic liposomal gene therapy with 16K human prolactin effi...
Published: November, 2009
Abstract: Human 16K PRL (16K hPRL) is a potent inhibitor of angiogenesis both in vitro and in vivo. It has been shown to prevent tumor growth in three xenogr... Read more »
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Master Mix
Sp1 mediate hypoxia induced ephrinB2 expression via a hypoxia-induc...
Published: October, 2009
Abstract: Environmental factors are instrumental in maintaining a healthy vasculature. Oxygen tension is higher in arteries than in veins and thus has the po... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The NF-kappaB factor RelB and histone H3 lysine methyltransferase G...
Published: October, 2009
Abstract: The interplay of transcription factors, histone modifiers, and DNA modification can alter chromatin structure that epigenetically controls gene tra... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chroma...
Published: October, 2009
Abstract: Activation of Janus kinase 2 (JAK2) by chromosomal translocations or point mutations is a frequent event in haematological malignancies. JAK2 is a ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
INTS3 controls the hSSB1-mediated DNA damage response.
Published: October, 2009
Abstract: Human SSB1 (single-stranded binding protein 1 [hSSB1]) was recently identified as a part of the ataxia telangiectasia mutated (ATM) signaling pathw... Read more »
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Bioruptor Cell Lysis Western Blot
The histone variant macroH2A is an epigenetic regulator of key deve...
Published: October, 2009
Abstract: The histone variants macroH2A1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the physiological function o... Read more »
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Antibody H3K4me3 (C15410003)
Development of a novel output value for quantitative assessment in ...
Published: October, 2009
Abstract: In DNA methylation microarray analysis, quantitative assessment of intermediate methylation levels in samples with various global methylation level... Read more »
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Antibody
Smad3 is required for normal follicular follicle-stimulating hormon...
Published: October, 2009
Abstract: Follicle-stimulating hormone (FSH) is the major regulator of folliculogenesis, but other factors modulate its action, including members of the tran... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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