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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Cooperation between the transcription factors p63 and IRF6 is essen...
Published: May, 2010
Abstract: Cleft palate is a common congenital disorder that affects up to 1 in 2,500 live human births and results in considerable morbidity to affected indi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Repression of transcriptional activity of C/EBPalpha by E2F-dimeriz...
Published: May, 2010
Abstract: The transcription factor CCAAT/enhancer-binding protein alpha (C/EBPalpha) coordinates proliferation arrest and the differentiation of myeloid prog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Profiling of promoter occupancy by PPARalpha in human hepatoma cell...
Published: May, 2010
Abstract: The transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha) is an important regulator of hepatic lipid metabolism. While ... Read more »
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Bioruptor Chromatin Shearing
Drosophila RB proteins repress differentiation-specific genes via t...
Published: May, 2010
Abstract: The RB and E2F proteins play important roles in the regulation of cell division, cell death, and development by controlling the expression of genes... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cooperation of NFkappaB and CREB to induce synergistic IL-6 express...
Published: May, 2010
Abstract: Astrocytes are critical players in the innate immune response of the central nervous system. Upon encountering proinflammatory stimuli, astrocytes ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Massively parallel sequencing, a new method for detecting adventiti...
Published: May, 2010
Abstract: There has been an upsurge of interest in developing new veterinary and human vaccines and, in turn, this has involved the development of new mammal... Read more »
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DNA shearing Bioruptor
Regulation of Epstein-Barr virus OriP replication by poly(ADP-ribos...
Published: May, 2010
Abstract: Poly(ADP-ribose) polymerase (PARP) is an abundant, chromatin-associated, NAD-dependent enzyme that functions in multiple chromosomal processes, inc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 ...
Published: May, 2010
Abstract: BACKGROUND: Multiple myeloma is an incurable malignancy of bone marrow plasma cells. Progression of multiple myeloma is accompanied by an increase ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Inhibitor of kappaB kinase beta regulates redox homeostasis by cont...
Published: May, 2010
Abstract: Cytokine-activated inhibitor of kappaB kinase beta (IKKbeta) is a key mediator of immune and inflammatory responses, but recent studies suggest tha... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Wilms' tumor gene 1 protein represses the expression of the tumor s...
Published: May, 2010
Abstract: Wilms' tumor gene 1 (WT1) is a transcription factor involved in developmental processes. In adult hematopoiesis, only a small portion of early prog... Read more »
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LowCell ChIP kit
Dnmt1/Transcription factor interactions: an alternative mechanism o...
Published: May, 2010
Abstract: DNA methylation inheritance is the process of copying, via the DNA methyltransferase 1 (Dnmt1), the pre-existing methylation patterns onto the new ... Read more »
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MeDIP kit
Estrogen receptor alpha controls a gene network in luminal-like bre...
Published: May, 2010
Abstract: Luminal-like breast tumor cells express estrogen receptor alpha (ERalpha), a member of the nuclear receptor family of ligand-activated transcriptio... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor...
Published: April, 2010
Abstract: The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
NER factors are recruited to active promoters and facilitate chroma...
Published: April, 2010
Abstract: Upon gene activation, we found that RNA polymerase II transcription machinery assembles sequentially with the nucleotide excision repair (NER) fact... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Orchestration of floral initiation by APETALA1.
Published: April, 2010
Abstract: The MADS-domain transcription factor APETALA1 (AP1) is a key regulator of Arabidopsis flower development. To understand the molecular mechanisms un... Read more »
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Bioruptor
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylatio...
Published: April, 2010
Abstract: Demethylation at distinct lysine residues in histone H3 by lysine-specific demethylase 1 (LSD1) causes either gene repression or activation. As a c... Read more »
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Antibody
A chromodomain switch mediated by histone H3 Lys 4 acetylation regu...
Published: April, 2010
Abstract: Chromodomain proteins (Chp1/Chp2/Swi6/Clr4) bind to methylated H3K9 (H3K9me) and regulate pericentric heterochromatin in fission yeast. Chp1 and Cl... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Targeted high throughput sequencing of a cancer-related exome subse...
Published: April, 2010
Abstract: Sequence capture methods for targeted next generation sequencing promise to massively reduce cost of genomics projects compared to untargeted seque... Read more »
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DNA shearing Bioruptor
Long intronic GAA repeats causing Friedreich ataxia impede transcri...
Published: April, 2010
Abstract: Friedreich ataxia is a degenerative disease caused by deficiency of the protein frataxin (FXN). An intronic expansion of GAA triplets in the FXN-en... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Autonomous silencing of the imprinted Cdkn1c gene in stem cells
Published: April, 2010
Abstract: Parent-of-origin specific expression of imprinted genes relies on the differential DNA methylation of specific genomic regions. Differentially meth... Read more »
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Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003) Histone ChIP kit
The male-determining gene SRY is a hybrid of DGCR8 and SOX3, and is...
Published: April, 2010
Abstract: In mammals, sex is determined by the presence or absence of the Y chromosome that bears a male-dominant sex-determining gene SRY, which switches th... Read more »
Regulation of photoreceptor gene expression by the retinal homeobox...
Published: March, 2010
Abstract: The retinal homeobox (Rx) gene product is essential for eye development. However little is known about its molecular function. It has been demonstr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNA methylome of familial breast cancer identifies distinct profile...
Published: March, 2010
Abstract: It is now understood that epigenetic alterations occur frequently in sporadic breast carcinogenesis, but little is known about the epigenetic alter... Read more »
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MeDIP kit
Distinct factors control histone variant H3.3 localization at speci...
Published: March, 2010
Abstract: The incorporation of histone H3 variants has been implicated in the epigenetic memory of cellular state. Using genome editing with zinc-finger nucl... Read more »
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Chromatin Shearing ChIP-qPCR
DNA methylation regulates adenosine A(2A) receptor cell surface exp...
Published: March, 2010
Abstract: Adenosine A(2A) receptors (A(2A)Rs) appear to play important roles in inflammation and in certain diseases of the nervous system. Pharmacological m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Splicing factor Spf30 assists exosome-mediated gene silencing in fi...
Published: March, 2010
Abstract: Heterochromatin assembly in fission yeast relies on the processing of cognate noncoding RNAs by both the RNA interference and the exosome degradati... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dr1 (NC2) is present at tRNA genes and represses their transcriptio...
Published: March, 2010
Abstract: Dr1 (also known as NC2beta) was identified as a repressor of RNA polymerase (pol) II transcription. It was subsequently shown to inhibit pol III tr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Bone morphogenetic protein-7 inhibits proximal tubular epithelial c...
Published: March, 2010
Abstract: Bone morphogenetic protein-7 (BMP-7) improves outcome in animal models of fibrotic renal disease by opposing transforming growth factor beta1 (TGF-... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Use of pJANUS-02-001 as a calibrator plasmid for Roundup Ready soyb...
Published: March, 2010
Abstract: Owing to the labelling requirements of food and feed products containing materials derived from genetically modified organisms, quantitative detect... Read more »
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Master Mix
Increased efficacy for in-house validation of real-time PCR GMO det...
Published: March, 2010
Abstract: To improve the efficacy of the in-house validation of GMO detection methods (DNA isolation and real-time PCR, polymerase chain reaction), a study w... Read more »
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Master Mix

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