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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates ...
Published: June, 2009
Abstract: The renin-angiotensin system (RAS) plays a crucial role in cardiovascular and neuronal (patho-)physiology. The angiotensin AT2 receptor (AT2R) seem... Read more »
Phosphorylation of histone H3 Thr-45 is linked to apoptosis.
Published: June, 2009
Abstract: Numerous post-translational modifications have been identified in histones. Most of these occur within the histone tails, but a few have been ident... Read more »
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Bioruptor Cell Lysis Western Blot
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bo...
Published: June, 2009
Abstract: Sustained angiogenesis, through either local sprouting (angiogenesis) or the recruitment of bone marrow-derived cells (BMDCs) (vasculogenesis), is ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A novel mechanism of antagonism between ATP-dependent chromatin rem...
Published: June, 2009
Abstract: Gene expression depends upon the antagonistic actions of chromatin remodeling complexes. While this has been studied extensively for the enzymes th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone H3 modifications associated with differentiation and long-t...
Published: June, 2009
Abstract: Long-term culture of mesenchymal stem cells leads to a loss of differentiation capacity, the molecular mechanism of which remains not understood. W... Read more »
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Antibody LowCell ChIP kit
Copper accumulation and compartmentalization in mouse fibroblast la...
Published: June, 2009
Abstract: Copper (Cu) is the active center of some enzymes because of its redox-active property, although that property could have harmful effects. Because o... Read more »
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Cell Lysis
The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor ...
Published: June, 2009
Abstract: Genomic integrity is threatened by multiple sources of DNA damage. DNA double-strand breaks (DSBs) are among the most dangerous types of DNA lesion... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gfi1 integrates progenitor versus granulocytic transcriptional prog...
Published: May, 2009
Abstract: In patients with severe congenital neutropenia (SCN) and mice with growth factor independent-1 (Gfi1) loss of function, arrested myeloid progenitor... Read more »
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Chromatin Shearing ChIP-qPCR
Magnet-guided transduction of mammalian cells and mice using engine...
Published: May, 2009
Abstract: Targeted delivery of therapeutic transgenes into specific cells remains a highly relevant challenge for tissue engineering and future gene-based th... Read more »
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Bioruptor
Characterization of the murine Ephrin-B2 promoter.
Published: May, 2009
Abstract: Eph/ephrin signaling is pivotal in prenatal angiogenesis. Although their role in these processes has been extensively studied the mechanisms contro... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate...
Published: May, 2009
Abstract: Ectopic repression of retinoic acid (RA) receptor target genes by PML/RARA and PLZF/RARA fusion proteins through aberrant recruitment of nuclear co... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rapid antibody selection by mRNA display on a microfluidic chip.
Published: May, 2009
Abstract: In vitro antibody-display technologies are powerful approaches for isolating monoclonal antibodies from recombinant antibody libraries. However, th... Read more »
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Cell Lysis
A comprehensive analysis of recruitment and transactivation potenti...
Published: April, 2009
Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma. K-Rta and K-bZIP are two major viral transcription facto... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Conversion of cholic acid and chenodeoxycholic acid into their 7-ox...
Published: April, 2009
Abstract: Secondary bile acid-producing bacteria were isolated from human feces to improve our appreciation of the functional diversity and redundancy of the... Read more »
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Cell Lysis Enzymatic Assay
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histo...
Published: March, 2009
Abstract: The linker histone H1 generally participates in the establishment of chromatin structure. However, of the seven somatic H1 isotypes in humans some ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cyclical chromatin looping and transcription factor association on ...
Published: March, 2009
Abstract: The nuclear receptor vitamin D receptor (VDR) is known to associate with three vitamin D response element (VDREs)-containing regions within the CDK... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signal...
Published: March, 2009
Abstract: The C. elegans insulin/IGF-1 signaling (IIS) cascade plays a central role in regulating life span, dauer, metabolism, and stress. The major regulat... Read more »
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Bioruptor Western Blot Tissue Homogenization
Role of 2-oxoglutarate dehydrogenase in brain pathologies involving...
Published: March, 2009
Abstract: Read more »
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Bioruptor Cell Lysis
The dynamic DNA methylomes of double-stranded DNA viruses associate...
Published: March, 2009
Abstract: The natural history of cancers associated with virus exposure is intriguing, since only a minority of human tissues infected with these viruses ine... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide regulon and crystal structure of BlaI (Rv1846c) from My...
Published: March, 2009
Abstract: Comparative genomics with Staphylococcus aureus suggested the existence of a regulatory system governing beta-lactamase (BlaC) production in Mycoba... Read more »
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Bioruptor Chromatin Shearing Cell Lysis
Relics of repeat-induced point mutation direct heterochromatin form...
Published: March, 2009
Abstract: Both RNAi-dependent and -independent mechanisms have been implicated in the establishment of heterochromatin domains, which may be stabilized by fe... Read more »
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Antibody
Genome-wide high throughput analysis of DNA methylation in eukaryotes.
Published: March, 2009
Abstract: Cytosine methylation is the quintessential epigenetic mark. Two well-established methods, bisulfite sequencing and methyl-DNA immunoprecipitation (... Read more »
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Antibody
Differential chromatin marking of introns and expressed exons by H3...
Published: March, 2009
Abstract: Variation in patterns of methylations of histone tails reflects and modulates chromatin structure and function. To provide a framework for the anal... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Temporal regulation of Ath5 gene expression during eye development.
Published: February, 2009
Abstract: During central nervous system development the timing of progenitor differentiation must be precisely controlled to generate the proper number and c... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Intestinal hypoxia-inducible transcription factors are essential fo...
Published: February, 2009
Abstract: Iron deficiency and iron overload are among the most prevalent nutritional disorders worldwide. Duodenal cytochrome b (DcytB) and divalent metal tr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The reelin and GAD67 promoters are activated by epigenetic drugs th...
Published: February, 2009
Abstract: The epigenetic down-regulation of genes is emerging as a possible underlying mechanism of the GABAergic neuron dysfunction in schizophrenia. For ex... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Nuclear factor-kappaB binds to the Epstein-Barr Virus LMP1 promoter...
Published: February, 2009
Abstract: The latent membrane protein 1 (LMP1) oncogene carried by Epstein-Barr virus (EBV) is essential for transformation and maintenance of EBV-immortaliz... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic ...
Published: February, 2009
Abstract: Patched (Ptch) heterozygous mice develop medulloblastoma (MB) and rhabdomyosarcoma (RMS) resembling the corresponding human tumors. We have previou... Read more »
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MeDIP kit
Survival motor neuron gene 2 silencing by DNA methylation correlate...
Published: January, 2009
Abstract: Spinal muscular atrophy (SMA), a common neuromuscular disorder, is caused by homozygous absence of the survival motor neuron gene 1 (SMN1), while t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependen...
Published: January, 2009
Abstract: Members of the sirtuin (SIRT) family of NAD-dependent deacetylases promote longevity in multiple organisms. Deficiency of mammalian SIRT6 leads to ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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