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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor reg...
Published: September, 2009
Abstract: Menin, the product of the MEN1 (multiple endocrine neoplasia type 1) tumor suppressor gene, is involved in activation of gene transcription as part... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of glucocorticoid receptor and hepatocyte nuclear ...
Published: September, 2009
Abstract: Hepatocyte nuclear factor 4alpha (HNF4alpha) plays a crucial role in hepatocyte differentiation, liver organogenesis and regulation of liver functi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ultradian hormone stimulation induces glucocorticoid receptor-media...
Published: September, 2009
Abstract: Studies on glucocorticoid receptor (GR) action typically assess gene responses by long-term stimulation with synthetic hormones. As corticosteroids... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ID1 promotes expansion and survival of primary erythroid cells and ...
Published: August, 2009
Abstract: The discovery of JAK2V617F as an acquired mutation in the majority of patients with myeloproliferative disorders (MPDs) and the key role of the JAK... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Targeting of EZH2 to a defined genomic site is sufficient for recru...
Published: August, 2009
Abstract: Polycomb-mediated gene silencing and DNA methylation underlie many epigenetic processes important in normal development as well as in cancer. An in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A...
Published: August, 2009
Abstract: HIC1, a tumor suppressor gene epigenetically silenced in many human cancers encodes a transcriptional repressor involved in regulatory loops modula... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Using ChIP-chip and ChIP-seq to study the regulation of gene expres...
Published: August, 2009
Abstract: Transcription is a sophisticated multi-step process in which RNA polymerase II (Pol II) transcribes a DNA template into RNA in concert with a broad... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
BRG1 increases transcription of proinflammatory genes in renal isch...
Published: August, 2009
Abstract: Acute kidney injury stimulates renal production of inflammatory mediators, including TNF-alpha and monocyte chemoattractant protein 1 (MCP-1). Thes... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Growth promotion and cell binding ability of bovine lactoferrin to ...
Published: August, 2009
Abstract: Lactoferrin, a major whey protein of human milk, is considered as growth promoter for bifidobacteria, the predominant microorganisms of human intes... Read more »
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Cell Lysis
High-resolution analysis of epigenetic changes associated with X in...
Published: August, 2009
Abstract: Differentiation of female murine ES cells triggers silencing of one X chromosome through X-chromosome inactivation (XCI). Immunofluorescence studie... Read more »
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Antibody H3K4me3 (C15410003)
CpG methylation controls reactivation of HIV from latency.
Published: August, 2009
Abstract: DNA methylation of retroviral promoters and enhancers localized in the provirus 5' long terminal repeat (LTR) is considered to be a mechanism of tr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cutting edge: SWI/SNF mediates antisense Igh transcription and locu...
Published: August, 2009
Abstract: The stepwise process of Ag receptor gene assembly, termed V(D)J recombination, is coordinated during lymphocyte development by sweeping changes in ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Drosophila MSL complex globally acetylates H4K16 on the male X chro...
Published: August, 2009
Abstract: The Drosophila melanogaster male-specific lethal (MSL) complex binds the single male X chromosome to upregulate gene expression to equal that from ... Read more »
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Bioruptor Chromatin Shearing
Endoplasmic reticulum stress regulates adipocyte resistin expression.
Published: August, 2009
Abstract: OBJECTIVE: Resistin is a secreted polypeptide that impairs glucose metabolism and, in rodents, is derived exclusively from adipocytes. In murine ob... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
p38 Mitogen-activated protein kinase- and HuR-dependent stabilizati...
Published: August, 2009
Abstract: Activation of p38 mitogen-activated protein kinase (MAPK) plays an important role in the G(2)/M cell cycle arrest induced by DNA damage, but little... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulon-specific control of transcription elongation across the yea...
Published: August, 2009
Abstract: Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Snail2 cooperates with Snail1 in the repression of vitamin D recept...
Published: August, 2009
Abstract: Vitamin D receptor (VDR) mediates the antitumoral action of the active vitamin D metabolite 1alpha,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). VDR ... Read more »
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Bioruptor Cell Lysis Western Blot
SWI/SNF and Asf1p cooperate to displace histones during induction o...
Published: August, 2009
Abstract: Regulation of the Saccharomyces cerevisiae HO promoter has been shown to require the recruitment of chromatin-modifying and -remodeling enzymes. De... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The fission yeast homeodomain protein Yox1p binds to MBF and confin...
Published: August, 2009
Abstract: The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional induction of SOX9 by NF-kappaB family member RelA i...
Published: August, 2009
Abstract: OBJECTIVE: Although SOX9 is a key molecule for chondrogenic differentiation, little is known about the upstream signal. The present study attempted... Read more »
Isolation of active regulatory elements from eukaryotic chromatin u...
Published: July, 2009
Abstract: The binding of sequence-specific regulatory factors and the recruitment of chromatin remodeling activities cause nucleosomes to be evicted from chr... Read more »
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Bioruptor Chromatin Shearing
Filter-based hybridization capture of subgenomes enables resequenci...
Published: July, 2009
Abstract: To exploit contemporary sequencing technologies for targeted genetic analyses, we developed a hybridization enrichment strategy for DNA capture tha... Read more »
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DNA shearing Bioruptor
Genistein induces adipogenesis but inhibits leptin induction in hum...
Published: July, 2009
Abstract: It was shown recently that synovial fibroblast transformation into adipocytes reduced the expression of interleukin-6 (IL-6) and IL-8. However, the... Read more »
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Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Histone methylation regulator PTIP is required for PPARgamma and C/...
Published: July, 2009
Abstract: PPARgamma and C/EBPalpha cooperate to control preadipocyte differentiation (adipogenesis). However, the factors that regulate PPARgamma and C/EBPal... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Global analysis of DNA methylation and transcription of human repet...
Published: July, 2009
Abstract: Half of the human genome consists of repetitive DNA sequences. Recent studies in various organisms highlight the role of chromatin regulation of re... Read more »
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DNA shearing Bioruptor
CRTC2 (TORC2) contributes to the transcriptional response to fastin...
Published: July, 2009
Abstract: The liver contributes to glucose homeostasis by promoting either storage or production of glucose, depending on the physiological state. The cAMP r... Read more »
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Bioruptor Western Blot Tissue Homogenization
H3K64 trimethylation marks heterochromatin and is dynamically remod...
Published: July, 2009
Abstract: Histone modifications are central to the regulation of all DNA-dependent processes. Lys64 of histone H3 (H3K64) lies within the globular domain at ... Read more »
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Antibody H3K4me3 (C15410003)
Improved Protocols for Illumina Sequencing
Published: July, 2009
Abstract: In this unit, we describe a set of improvements we have made to the standard Illumina protocols to make the sequencing process more reliable in a h... Read more »
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DNA shearing Bioruptor
The human CD6 gene is transcriptionally regulated by RUNX and Ets t...
Published: July, 2009
Abstract: CD6 is a lymphocyte surface receptor involved in lymphocyte activation and differentiation processes that is constitutively expressed on developing... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Metabolic intermediates selectively stimulate transcription factor ...
Published: June, 2009
Abstract: Cells use strategic metabolites to sense the metabolome and accordingly modulate gene expression. Here, we show that the purine and phosphate pathw... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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