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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

RNAi-dependent H3K27 methylation is required for heterochromatin fo...
Published: June, 2007
Abstract: Methylated H3K27 is an important mark for Polycomb group (PcG) protein-mediated transcriptional gene silencing (TGS) in multicellular eukaryotes. H... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Notch activation stimulates transient and selective binding of Su(H...
Published: June, 2007
Abstract: The CSL [CBF1/Su(H)/Lag2] proteins [Su(H) in Drosophila] are implicated in repression and activation of Notch target loci. Prevailing models imply ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
CHD4/Mi-2beta activity is required for the positioning of the mesod...
Published: April, 2007
Abstract: Experiments in Xenopus have illustrated the importance of extracellular morphogens for embryonic gene regulation in vertebrates. Much less is known... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ubiquitylation of histone H2B controls RNA polymerase II transcript...
Published: April, 2007
Abstract: Transcription by RNA polymerase II (polII) is accompanied by dramatic changes in chromatin structure. Numerous enzymatic activities contribute to t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Carbon nanotube polymer composites for photonic devices
Published: March, 2007
Abstract: We report the fabrication of high optical quality single wall carbon nanotube polyvinyl alcohol composites and their application in nanotube based ... Read more »
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Bioruptor
Identification of novel functional TBP-binding sites and general fa...
Published: February, 2007
Abstract: Our current knowledge of the general factor requirement in transcription by the three mammalian RNA polymerases is based on a small number of model... Read more »
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Antibody
An unmethylated 3' promoter-proximal region is required for efficie...
Published: February, 2007
Abstract: The promoter regions of approximately 40% of genes in the human genome are embedded in CpG islands, CpG-rich regions that frequently extend on the ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genetic unmasking of an epigenetically silenced microRNA in human c...
Published: February, 2007
Abstract: The mechanisms underlying microRNA (miRNA) disruption in human disease are poorly understood. In cancer cells, the transcriptional silencing of tum... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Modulation of drug-stimulated ATPase activity of human MDR1/P-glyco...
Published: January, 2007
Abstract: MDR1 (multidrug resistance 1)/P-glycoprotein is an ATP-driven transporter which excretes a wide variety of structurally unrelated hydrophobic compo... Read more »
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Liposome Preparation
Reciprocal regulation of p63 by C/EBP delta in human keratinocytes.
Published: January, 2007
Abstract: BACKGROUND: Genetic experiments have clarified that p63 is a key transcription factor governing the establishment and maintenance of multilayered e... Read more »
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Antibody
H3K9 methylation and RNA interference regulate nucleolar organizati...
Published: January, 2007
Abstract: Investigations aimed at identifying regulators of nuclear architecture in Drosophila demonstrated that cells lacking H3K9 methylation and RNA inter... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic regulation of histone H3 serine 10 phosphorylation statu...
Published: January, 2007
Abstract: BACKGROUND: The human herpes simplex virus (HSV) host cell factor HCF-1 is a transcriptional coregulator that associates with both histone methyl- ... Read more »
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Bioruptor Tissue Homogenization
JunB is required for endothelial cell morphogenesis by regulating c...
Published: December, 2006
Abstract: The molecular mechanism triggering the organization of endothelial cells (ECs) in multicellular tubules is mechanistically still poorly understood.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Protein interactions within the Set1 complex and their roles in the...
Published: November, 2006
Abstract: Set1 is the catalytic subunit and the central component of the evolutionarily conserved Set1 complex (Set1C) that methylates histone 3 lysine 4 (H3... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xis...
Published: October, 2006
Abstract: Initiation of X inactivation depends on the coordinated expression of the sense/antisense pair Xist/Tsix. We show here that a precisely defined Xis... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Architecture of a polycomb nucleoprotein complex.
Published: October, 2006
Abstract: Polycomb group (PcG) epigenetic silencing proteins act through cis-acting DNA sequences, named Polycomb response elements (PREs). Within PREs, Plei... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Glutaredoxin modulates platelet-derived growth factor-dependent cel...
Published: September, 2006
Abstract: Glutaredoxin (GRX) is a glutathione-disulfide oxidoreductase involved in various cellular functions, including the redox-dependent regulation of ce... Read more »
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Cell Lysis
A profile of methyl-CpG binding domain protein occupancy of hyperme...
Published: September, 2006
Abstract: Methyl-CpG binding domain (MBD) proteins have been shown to couple DNA methylation to transcriptional repression. This biological property suggests... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Influenza virus inhibits RNA polymerase II elongation.
Published: July, 2006
Abstract: The influenza virus RNA-dependent RNA polymerase interacts with the serine-5 phosphorylated carboxy-terminal domain (CTD) of the large subunit of R... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
BEAMing: single-molecule PCR on microparticles in water-in-oil emul...
Published: July, 2006
Abstract: Read more »
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Bioruptor
Menin links estrogen receptor activation to histone H3K4 trimethyla...
Published: May, 2006
Abstract: The product of the multiple endocrine neoplasia type 1 (MEN1) tumor suppressor gene, menin, is an integral component of MLL1/MLL2 histone methyltra... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Effects of various growth conditions in a chemostat on expression o...
Published: May, 2006
Abstract: Porphyromonas gingivalis, one of the gram-negative organisms associated with periodontal disease, possesses potential virulence factors, including ... Read more »
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Cell Lysis
The hemoglobin receptor protein of porphyromonas gingivalis inhibit...
Published: May, 2006
Abstract: Extracellular proteinaceous factors of Porphyromonas gingivalis, a periodontal pathogen, that influence receptor activator of nuclear factor-kappaB... Read more »
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Cell Lysis Western Blot
The Polycomb group protein EZH2 directly controls DNA methylation.
Published: February, 2006
Abstract: The establishment and maintenance of epigenetic gene silencing is fundamental to cell determination and function. The essential epigenetic systems ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The benzamide MS-275 is a potent, long-lasting brain region-selecti...
Published: January, 2006
Abstract: The association of the histone deacetylase (HDAC) inhibitor valproate (VPA) with atypical antipsychotics has become a frequent treatment strategy f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA...
Published: October, 2005
Abstract: We screened radiation-sensitive yeast mutants for DNA damage checkpoint defects and identified Dot1, the conserved histone H3 Lys 79 methyltransfer... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Defective CD3gamma gene transcription is associated with NFATc2 ove...
Published: October, 2005
Abstract: OBJECTIVE: Determine the molecular defects underlying the CD3(-)CD4(+) T-cell phenotype and persistence of this clonal population in patients with ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cell lysis directed by sigmaE in early stationary phase and effect ...
Published: August, 2005
Abstract: It has been shown that Escherichia coli cells with increased expression of the rpoE gene encoding sigma(E) exhibit enhanced cell lysis in early sta... Read more »
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Cell Lysis
Identification of a novel adhesion molecule involved in the virulen...
Published: July, 2005
Abstract: Legionella pneumophila is an intracellular bacterium, and its successful parasitism in host cells involves two reciprocal phases: transmission and ... Read more »
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Cell Lysis
Membrane binding properties and terminal residues of the mature hep...
Published: November, 2004
Abstract: The immature core protein (p23, residues 1 to 191) of hepatitis C virus undergoes posttranslational modifications including intramembranous proteol... Read more »

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