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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The prolyl-isomerase PIN1 is essential for nuclear Lamin-Bstructure...
Published: September, 2021
Abstract: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposab... Read more »
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Antibody
DOT1L O-GlcNAcylation promotes its protein stability andMLL-fusion ...
Published: September, 2021
Abstract: Histone lysine methylation functions at the interface of the extracellular environment and intracellular gene expression. DOT1L is a versatile hist... Read more »
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Antibody
WT1 regulates HOXB9 gene expression in a bidirectional way.
Published: September, 2021
Abstract: The homeoboxB9 (HOXB9) gene is necessary for specification of the anterior-posterior body axis during embryonic development and expressed in variou... Read more »
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Antibody
INTS11 regulates hematopoiesis by promoting PRC2 function.
Published: September, 2021
Abstract: INTS11, the catalytic subunit of the Integrator (INT) complex, is crucial for the biogenesis of small nuclear RNAs and enhancer RNAs. However, the ... Read more »
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Antibody Microplex Library Preparation kit
Histone deacetylase 4 deletion broadly affects cardiac epigeneticre...
Published: September, 2021
Abstract: Histone deacetylase 4 (HDAC4) is a member of class IIa histone deacetylases (class IIa HDACs) and is believed to possess a low intrinsic deacetylas... Read more »
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IP-Star Antibody
Genome-wide epigenomic analyses in patients with nociceptive andneu...
Published: September, 2021
Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
The related coactivator complexes SAGA and ATAC control embryonicst...
Published: September, 2021
Abstract: SUMMARY SAGA (Spt-Ada-Gcn5 acetyltransferase) and ATAC (Ada-two-A-containing) are two related coactivator complexes, sharing the same histone acety... Read more »
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Microplex Library Preparation kit
De novo genome assembly of the marine teleost, bluefin trevally (Ca...
Published: September, 2021
Abstract: The bluefin trevally, Caranx melampygus, also known as the bluefin kingfish or bluefin jack, is known for its remarkable, bright-blue fins. This ma... Read more »
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Megaruptor
Genome-wide and sister chromatid-resolved profiling of protein occu...
Published: September, 2021
Abstract: Elucidating the mechanisms underlying chromatin maintenance upon genome replication is critical for the understanding of how gene expression progra... Read more »
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Antibody
Epigenetic remodelling of enhancers in response to estrogen depriva...
Published: September, 2021
Abstract: Estrogen hormones are implicated in a majority of breast cancers and estrogen receptor alpha (ER), the main nuclear factor mediating estrogen signa... Read more »
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Antibody iDeal ChIP-seq Kit for Histones iDeal ChIP-qPCR hMeDIP
Biobehavioral organization shapes the immune epigenome in infant rh...
Published: August, 2021
Abstract: How individuals respond to and cope with stress is linked with their health and well-being. It is presumed that early stress responsiveness helps s... Read more »
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Premium RRBS Kit
Functional microRNA targetome undergoes degeneration-induced shift ...
Published: August, 2021
Abstract: BACKGROUND: MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degene... Read more »
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D-Plex small RNA-seq
Activated Histone Acetyltransferase p300/CBP-Related SignallingPath...
Published: August, 2021
Abstract: Accumulating evidence implicates the histone acetylation-based epigenetic mechanisms in the pathoetiology of diabetes-associated micro-/macrovascul... Read more »
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Antibody
Aiolos regulates eosinophil migration into tissues.
Published: August, 2021
Abstract: Expression of Ikaros family transcription factor IKZF3 (Aiolos) increases during murine eosinophil lineage commitment and maturation. Herein, we in... Read more »
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Antibody
Targeted long-read sequencing identifies missing disease-causingvar...
Published: August, 2021
Abstract: Despite widespread clinical genetic testing, many individuals with suspected genetic conditions lack a precise diagnosis, limiting their opportunit... Read more »
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Megaruptor
Establishment of two homozygous CRISPR interference (CRISPRi)knock-...
Published: August, 2021
Abstract: Using nuclease-deficient dead (d)Cas9 without enzymatic activity fused to transcriptional inhibitors (CRISPRi) allows for transcriptional interfere... Read more »
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Antibody CRISPR
Bisection of the X chromosome disrupts the initiation of chromosome...
Published: August, 2021
Abstract: During meiosis, gene expression is silenced in aberrantly unsynapsed chromatin and in heterogametic sex chromosomes. Initiation of sex chromosome s... Read more »
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Antibody
Evidence of an epidemic spread of KPC-producing in Czech hospitals
Published: August, 2021
Abstract: The aim of the present study is to describe the ongoing spread of the KPC-producing strains, which is evolving to an epidemic in Czech hospitals. D... Read more »
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Megaruptor
Altered Chromatin States Drive Cryptic Transcription in AgingMammal...
Published: August, 2021
Abstract: A repressive chromatin state featuring trimethylated lysine 36 on histone H3 (H3K36me3) and DNA methylation suppresses cryptic transcription in emb... Read more »
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Antibody Microplex Library Preparation kit True MicroChIP kit
Essential role of a ThPOK autoregulatory loop in the maintenance of...
Published: August, 2021
Abstract: The transcription factor ThPOK (encoded by the Zbtb7b gene) controls homeostasis and differentiation of mature helper T cells, while opposing their... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Niche stiffening compromises hair follicle stem cell potential duri...
Published: July, 2021
Abstract: Tissue turnover requires activation and lineage commitment of tissue-resident stem cells (SCs). These processes are impacted by ageing, but the mec... Read more »
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ChIPmentation
Phase separation drives aberrant chromatin looping and cancerdevelo...
Published: July, 2021
Abstract: The development of cancer is intimately associated with genetic abnormalities that target proteins with intrinsically disordered regions (IDRs). In... Read more »
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Antibody
Light affects behavioral despair involving the clock gene Period 1.
Published: July, 2021
Abstract: Light at night has strong effects on physiology and behavior of mammals. It affects mood in humans, which is exploited as light therapy, and has be... Read more »
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D-Plex RNA-seq kit
Enhanced targeted DNA methylation of the CMV and endogenous promote...
Published: July, 2021
Abstract: With the emergence of new CRISPR/dCas9 tools that enable site specific modulation of DNA methylation and histone modifications, more detailed inves... Read more »
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Antibody iDeal ChIP-qPCR
Complete Genome Sequence of pv. tabaci Strain 6605, a Causal Agent...
Published: July, 2021
Abstract: ABSTRACT Pseudomonas amygdali pv. tabaci strain 6605 is the bacterial pathogen causing tobacco wildfire disease that has been used as a mod... Read more »
Evidence for long-term association of virion-delivered HBV core pro...
Published: July, 2021
Abstract: Background \& Aims HBV persists in the nucleus of infected hepatocytes as a covalently closed circular DNA (cccDNA) episome that constitutes th... Read more »
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Antibody
The USDA-ARS Ag100Pest Initiative: High-Quality GenomeAssemblies fo...
Published: July, 2021
Abstract: Simple Summary High-quality genome assemblies are essential tools for modern biological research. In the past, creating genome assemblies was prohi... Read more »
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Megaruptor
Epigenetic Drifts during Long-Term Intestinal OrganoidCulture
Published: July, 2021
Abstract: Organoids retain the morphological and molecular patterns of their tissue of origin, are self-organizing, relatively simple to handle and accessibl... Read more »
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IP-Star iDeal ChIP-seq Kit for Histones
Metabolically controlled histone H4K5 acylation/acetylation ratiodr...
Published: July, 2021
Abstract: In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and ... Read more »
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Microplex Library Preparation kit
Single-cell microRNA sequencing method comparison and application t...
Published: July, 2021
Abstract: Molecular single cell analyses provide insights into physiological and pathological processes. Here, in a stepwise approach, we first evaluate 19 p... Read more »
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D-Plex small RNA-seq

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