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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Restricted nucleation and piRNA-mediated establishment of heterochr...
Published: February, 2021
Abstract: Heterochromatin is a key architectural feature of eukaryotic genomes, crucial for silencing of repetitive elements and maintaining genome stability... Read more »
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Antibody
The epigenetic landscape in purified myonuclei from fast and slow m...
Published: February, 2021
Abstract: Muscle cells have different phenotypes adapted to different usage and can be grossly divided into fast/glycolytic and slow/oxidative types. While m... Read more »
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Antibody
Environmental enrichment induces epigenomic and genome organization...
Published: February, 2021
Abstract: In early development, the environment triggers mnemonic epigenomic programs resulting in memory and learning experiences to confer cognitive phenot... Read more »
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Antibody
Chromatin dysregulation associated with NSD1 mutation in head and n...
Published: February, 2021
Abstract: Chromatin dysregulation has emerged as an important mechanism of oncogenesis. To develop targeted treatments, it is important to understand the tra... Read more »
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Antibody Bioruptor Plus IP-Star Compact
Kmt2c mutations enhance HSC self-renewal capacity and convey a sele...
Published: February, 2021
Abstract: The myeloid tumor suppressor KMT2C is recurrently deleted in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), particularly therapy-... Read more »
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Antibody
The glucocorticoid receptor recruits the COMPASS complex to regulat...
Published: February, 2021
Abstract: Glucocorticoids (GCs) are effective anti-inflammatory drugs; yet, their mechanisms of action are poorly understood. GCs bind to the glucocorticoid ... Read more »
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Antibody
A distinct metabolic response characterizes sensitivity to EZH2inhi...
Published: February, 2021
Abstract: Multiple myeloma (MM) is a heterogeneous haematological disease that remains clinically challenging. Increased activity of the epigenetic silencer ... Read more »
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iDeal ChIP-seq Kit for Histones
A brain cyst load-associated antigen is a Toxoplasma gondii biomark...
Published: February, 2021
Abstract: BACKGROUND: Biomarker discovery remains a major challenge for predictive medicine, in particular, in the context of chronic diseases. This is true ... Read more »
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IPure kit iDeal ChIP-seq Kit for Histones
BAF complexes drive proliferation and block myogenic differentiatio...
Published: January, 2021
Abstract: Rhabdomyosarcoma (RMS) is a pediatric malignancy of skeletal muscle lineage. The aggressive alveolar subtype is characterized by t(2;13) or t(1;13)... Read more »
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Chromatin Shearing iDeal ChIP-seq Kit for Transcription Factors
A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia
Published: January, 2021
Abstract: Long-range oncogenic enhancers play an important role in cancer. Yet, whether similar regulation of tumor suppressor genes is relevant remains uncl... Read more »
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Antibody IP-Star Compact
Developmental cannabidiol exposure increases anxiety and modifiesge...
Published: January, 2021
Abstract: BACKGROUND: Use of cannabidiol (CBD), the primary non-psychoactive compound found in cannabis, has recently risen dramatically, while relatively li... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.ZAcety...
Published: January, 2021
Abstract: Histone variants differ in amino acid sequence, expression timing and genomic localization sites from canonical histones and convey unique function... Read more »
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Microplex Library Preparation kit
Genomic Characterization of VIM and MCR Co-Producers: The First Two...
Published: January, 2021
Abstract: BACKGROUND: the co-production of carbapenemases and -genes represents a worrisome event in the treatment of infections. The aim of the study was to... Read more »
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Megaruptor
Epigenetic impairment and blunted transcriptional response to Mycob...
Published: January, 2021
Abstract: Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of recent infection with Mycobacte... Read more »
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Microplex Library Preparation kit
IGFBP2 protects against pulmonary fibrosis through inhibiting P21-m...
Published: January, 2021
Abstract: Accumulation of senescent cells contributes to age related diseases including idiopathic pulmonary fibrosis (IPF). Insulin-like growth factor bindi... Read more »
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DNA Methylation Profiling (RRBS Service)
Perturbed DNA methylation by sustained overexpression of Gadd45b in...
Published: January, 2021
Abstract: Heterochromatin disorganization is a key hallmark of aging and DNA methylation state is currently the main molecular predictor of chronological age... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Stronger induction of trained immunity by mucosal BCG or MTBVAC vac...
Published: January, 2021
Abstract: BCG vaccination can strengthen protection against pathogens through the induction of epigenetic and metabolic reprogramming of innate immune cells,... Read more »
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Antibody
FOS licenses early events in stem cell activation driving skeletal ...
Published: January, 2021
Abstract: Muscle satellite cells (SCs) are a quiescent (non-proliferative) stem cell population in uninjured skeletal muscle. Although SCs have been investig... Read more »
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iDeal ChIP-qPCR
The Essential Function of SETDB1 in Homologous Chromosome Pairing a...
Published: January, 2021
Abstract: SETDB1 is a histone-lysine N-methyltransferase critical for germline development. However, its function in early meiotic prophase I remains unknown... Read more »
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Antibody
Interspecies RNA Interactome of Pathogen and Host in a Heritable De...
Published: January, 2021
Abstract: Communication with bacteria deeply impacts the life history traits of their hosts. Through specific molecules and metabolites, bacteria can promote... Read more »
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D-Plex small RNA-seq
Distinct Extracellular RNA Profiles in Different PlasmaComponents.
Published: January, 2021
Abstract: Circulating extracellular RNAs (exRNAs) have great potential to serve as biomarkers for a wide range of diagnostic, therapeutic, and prognostic app... Read more »
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D-Plex small RNA-seq
Detection of genetic variation and base modifications at base-pairr...
Published: January, 2021
Abstract: Accurate decoding of nucleic acid variation is critical to understand the complexity and regulation of genome function. Here we use a single-molecu... Read more »
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Antibody
Histone demethylase JMJD2B/KDM4B regulates transcriptional program ...
Published: January, 2021
Abstract: Trophoblast stem cell (TSC) is crucial to the formation of placenta in mammals. Histone demethylase JMJD2 (also known as KDM4) family proteins have... Read more »
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Microplex Library Preparation kit
Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage.
Published: January, 2021
Abstract: HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed underst... Read more »
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Antibody
The Identification of a Novel Fucosidosis-Associated Mutation: A C...
Published: January, 2021
Abstract: Fucosidosis is a rare neurodegenerative autosomal recessive disorder, which manifests as progressive neurological and psychomotor deterioration, gr... Read more »
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Premium RRBS Kit
Chromosome-scale genome assembly provides insights into the evoluti...
Published: January, 2021
Abstract: Passion fruit (Passiflora edulis Sims) is an economically valuable fruit that is cultivated in tropical and subtropical regions of the world. Here,... Read more »
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Megaruptor
Postoperative abdominal sepsis induces selective and persistent cha...
Published: January, 2021
Abstract: BACKGROUND: Postoperative abdominal infections belong to the most common triggers of sepsis and septic shock in intensive care units worldwide. Whi... Read more »
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Antibody IP-Star Compact iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
Genome-wide DNA methylation and RNA-seq analyses identify genes and...
Published: January, 2021
Abstract: Doxorubicin resistance is a major challenge in the successful treatment of canine diffuse large B-cell lymphoma (cDLBCL). In the present study, Met... Read more »
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MethylCap kit
Prenatal Stress Leads to the Altered Maturation of Corticostriatal ...
Published: January, 2021
Abstract: Prenatal stress (PRS) had a long-term adverse effect on motor behaviors. Corticostriatal synaptic plasticity, a cellular basis for motor controllin... Read more »
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MagMeDIP kit
CREB3 Transactivates lncRNA ZFAS1 to Promote PapillaryThyroid Carci...
Published: January, 2021
Abstract: The incidence rate of thyroid carcinoma ranks ninth among human malignancies, and it accounts for the most frequent malignancy in endocrine-related... Read more »
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iDeal ChIP-qPCR

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