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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A Chromosomal Duplication Encompassing Interleukin-33 Causes aNovel...
Published: April, 2022
Abstract: Interleukin (IL)-33 is a member of the IL-1 cytokine family and is secreted by fibroblasts, endothelial cells, and epithelial cells in tissues (lun... Read more »
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D-Plex RNA-seq kit
Folic Acid Treatment Directly Influences the Genetic andEpigenetic ...
Published: April, 2022
Abstract: Folic acid (FA) is a synthetic form of vitamin B9, generally used as a nutritional supplement and an adjunctive medication in cancer therapy. FA is... Read more »
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Premium RRBS Kit
The CpG Island-Binding Protein SAMD1 Contributes to anUnfavorable G...
Published: April, 2022
Abstract: The unmethylated CpG island-binding protein SAMD1 is upregulated in many human cancer types, but its cancer-related role has not yet been investiga... Read more »
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Bioruptor Antibody Microplex Library Preparation kit
An obesogenic feedforward loop involving PPARγ, acyl-CoA bindingpro...
Published: April, 2022
Abstract: Acyl-coenzyme-A-binding protein (ACBP), also known as a diazepam-binding inhibitor (DBI), is a potent stimulator of appetite and lipogenesis. Bioin... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
MLL-AF4 and a murinized pSer-variant thereof are turning on thenucl...
Published: April, 2022
Abstract: BACKGROUND: Recent pathomolecular studies on the MLL-AF4 fusion protein revealed that the murinized version of MLL-AF4, the MLL-Af4 fusion protein,... Read more »
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Bioruptor Antibody
Assessment of TET1 gene expression, DNA methylation and H3K27me3lev...
Published: April, 2022
Abstract: Endometriosis is the cause of infertility. The eutopic endometrium of women with endometriosis showed an aberrant expression pattern of multitude g... Read more »
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Chromatin Shearing Antibody
Familial long-read sequencing increases yield of de novo mutations.
Published: April, 2022
Abstract: Studies of de novo mutation (DNM) have typically excluded some of the most repetitive and complex regions of the genome because these regions canno... Read more »
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Megaruptor
Local euchromatin enrichment in lamina-associated domains anticipat...
Published: April, 2022
Abstract: BACKGROUND: Interactions of chromatin with the nuclear lamina via lamina-associated domains (LADs) confer structural stability to the genome. The d... Read more »
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Antibody Microplex Library Preparation kit
Transposon activity, local duplications and propagation of structur...
Published: April, 2022
Abstract: BACKGROUND: Immortalized cell lines are widely used model systems whose genomes are often highly rearranged and polyploid. However, their genome st... Read more »
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Megaruptor
ZWC complex-mediated SPT5 phosphorylation suppresses divergentantis...
Published: April, 2022
Abstract: The human genome encodes large numbers of non-coding RNAs, including divergent antisense transcripts at transcription start sites (TSSs). However, ... Read more »
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Antibody
The genome sequence of Anoplius nigerrimus (Scopoli, 1763), a spide...
Published: April, 2022
Abstract: We present a genome assembly from an individual Anoplius nigerrimus (Arthropoda; Insecta; Hymenoptera; Pompilidae) of unknown sex. The genome seque... Read more »
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Megaruptor
Immune disease variants modulate gene expression in regulatory CD4T...
Published: April, 2022
Abstract: Identifying cellular functions dysregulated by disease-associated variants could implicate novel pathways for drug targeting or modulation in cell ... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
SMYD5 is a histone H3-specific methyltransferase mediatingmono-meth...
Published: April, 2022
Abstract: Although post-translational modifications (-PTMs) of some histone H3 lysine residues are well studied, the PTMs of histone H3 lysine 37 in mammalia... Read more »
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Antibody
Environmental induced transgenerational inheritance impacts systems...
Published: April, 2022
Abstract: Environmental toxicants have been shown to promote the epigenetic transgenerational inheritance of disease through exposure specific epigenetic alt... Read more »
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Antibody
A leukemia-protective germline variant mediates chromatin modulefor...
Published: April, 2022
Abstract: Non-coding variants coordinate transcription factor (TF) binding and chromatin mark enrichment changes over regions spanning >100 kb. The... Read more »
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Antibody
Decitabine increases neoantigen and cancer testis antigen expressio...
Published: April, 2022
Abstract: BACKGROUND: Glioblastoma (GBM) is the most common and malignant primary brain tumour in adults. Despite maximal treatment, median survival remains ... Read more »
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Infinium Human MethylationEPIC Array Service
Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3and ...
Published: April, 2022
Abstract: Precision epigenome editing has gained significant attention as a method to modulate gene expression without altering genetic information. However,... Read more »
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Antibody
Broad domains of histone marks in the highly compact macronuclearg...
Published: April, 2022
Abstract: The unicellular ciliate contains a large vegetative macronucleus with several unusual characteristics, including an extremely high coding density a... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enha...
Published: March, 2022
Abstract: Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but s... Read more »
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IP-Star Antibody Microplex Library Preparation kit iDeal ChIP-seq Kit for Histones Chromatin Profiling (ChIP-seq) Services
Haplotype-resolved Chinese male genome assembly based on high-fidel...
Published: March, 2022
Abstract: The advantages of both the length and accuracy of high-fidelity (HiFi) reads enable chromosome-scale haplotype-resolved genome assembly. In this st... Read more »
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Megaruptor
GBS-MeDIP: A protocol for parallel identification of genetic andepi...
Published: March, 2022
Abstract: The GBS-MeDIP protocol combines two previously described techniques, Genotype-by-Sequencing (GBS) and Methylated-DNA-Immunoprecipitation (MeDIP). O... Read more »
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Antibody
H3K9 dimethylation safeguards cancer cells against activation of th...
Published: March, 2022
Abstract: Activation of interferon genes constitutes an important anticancer pathway able to restrict proliferation of cancer cells. Here, we demonstrate tha... Read more »
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Antibody
Complex regulatory role of DNA methylation in caste- and age-specif...
Published: March, 2022
Abstract: The reproductive castes of eusocial insects are often characterised by extreme lifespans and reproductive output, indicating an absence of the fecu... Read more »
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Premium RRBS Kit
Evaluation of N6-adenine DNA-immunoprecipitation-basedgenomic profi...
Published: March, 2022
Abstract: The detection of low-abundance DNA N6-methyladenine (DNA-m6A) remains challenging, limiting our understanding of this novel base in eukaryotes. To ... Read more »
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Antibody
Phylogenomics and Comparative Genomics Highlight SpecificGenetic Fe...
Published: March, 2022
Abstract: The species in Polyporales are ecologically and economically relevant wood decayers used in traditional medicine, but their genomic traits are stil... Read more »
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Megaruptor
Complete Genome Sequence of Herpes Simplex Virus 2 StrainG.
Published: March, 2022
Abstract: Herpes simplex virus type (HSV-2) is a common causative agent of genital tract infections. Moreover, HSV-2 and HIV infection can mutually increase ... Read more »
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Megaruptor
Preterm birth buccal cell epigenetic biomarkers to facilitatepreven...
Published: March, 2022
Abstract: Preterm birth is the major cause of newborn and infant mortality affecting nearly one in every ten live births. The current study was designed to d... Read more »
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Antibody
Avian influenza viruses suppress innate immunity by inducingtrans-t...
Published: March, 2022
Abstract: Innate immunity plays critical antiviral roles. The highly virulent avian influenza viruses (AIVs) H5N1, H7N9, and H5N6 can better escape host inna... Read more »
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Antibody CRISPR
Corticosterone induces discrete epigenetic signatures in the dorsal...
Published: March, 2022
Abstract: The genomic effects of circulating glucocorticoids are particularly relevant in cortico-limbic structures, which express a high concentration of st... Read more »
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MagMeDIP kit
Regulation of paternal 5mC oxidation and H3K9me2 asymmetry byERK1/2...
Published: March, 2022
Abstract: BACKGROUND: Extracellular-signal-regulated kinase (ERK) direct cell fate determination during the early development. The intricate interaction betw... Read more »
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Antibody

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