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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

ChIP-seq of plasma cell-free nucleosomes identifies cell-of-origin ...
Published: May, 2019
Abstract: Blood cell-free DNA (cfDNA) is derived from fragmented chromatin in dying cells. As such, it remains associated with histones that may retain the c... Read more »
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Antibody
Canonical PRC1 controls sequence-independent propagation of Polycom...
Published: April, 2019
Abstract: Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catal... Read more »
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Antibody
Genome-wide DNA methylation profiles in Tibetan and Yorkshire pigs ...
Published: April, 2019
Abstract: Background: Tibetan pigs, which inhabit the Tibetan Plateau, exhibit distinct phenotypic and physiological characteristics from those of lowland pi... Read more »
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MagMeDIP kit
P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Res...
Published: April, 2019
Abstract: DNA damage response (DDR) involves dramatic transcriptional alterations, the mechanisms of which remain ill defined. Here, we show that following g... Read more »
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Bioruptor
BRCA1 mutations attenuate super-enhancer function and chromatin loo...
Published: April, 2019
Abstract: BACKGROUND: BRCA1-associated breast cancer originates from luminal progenitor cells. BRCA1 functions in multiple biological processes, including do... Read more »
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Microplex Library Preparation kit
PML modulates H3.3 targeting to telomeric and centromeric repeats i...
Published: April, 2019
Abstract: Targeted deposition of histone variant H3.3 into chromatin is paramount for proper regulation of chromatin integrity, particularly in heterochromat... Read more »
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Antibody
Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecul...
Published: April, 2019
Abstract: Studies in vertebrates have outlined conserved molecular control of definitive endoderm (END) development. However, recent work also shows that key... Read more »
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Antibody
The Reference Genome Sequence of Scutellaria baicalensis Provides I...
Published: April, 2019
Abstract: Scutellaria baicalensis Georgi is important in Chinese traditional medicine where preparations of dried roots, "Huang Qin," are used for liver and ... Read more »
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Megaruptor
Long intergenic non-coding RNAs regulate human lung fibroblast func...
Published: April, 2019
Abstract: Phenotypic changes in lung fibroblasts are believed to contribute to the development of Idiopathic Pulmonary Fibrosis (IPF), a progressive and fata... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Defining UHRF1 Domains that Support Maintenance of Human Colon Canc...
Published: April, 2019
Abstract: UHRF1 facilitates the establishment and maintenance of DNA methylation patterns in mammalian cells. The establishment domains are defined, includin... Read more »
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Antibody
TET3 prevents terminal differentiation of adult NSCs by a non-catal...
Published: April, 2019
Abstract: Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, altho... Read more »
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Antibody
Dissecting the role of H3K27 acetylation and methylation in PRC2 me...
Published: April, 2019
Abstract: The Polycomb repressive complexes PRC1 and PRC2 act non-redundantly at target genes to maintain transcriptional programs and ensure cellular identi... Read more »
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Antibody
Essential Gene Profiles for Human Pluripotent Stem Cells Identify U...
Published: April, 2019
Abstract: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding... Read more »
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Antibody
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphoc...
Published: April, 2019
Abstract: Increased glycolysis parallels immune cell activation, but the role of pyruvate remains largely unexplored. We found that stimulation of dendritic ... Read more »
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Antibody
Identification of ADGRE5 as discriminating MYC target between Burki...
Published: April, 2019
Abstract: BACKGROUND: MYC is a heterogeneously expressed transcription factor that plays a multifunctional role in many biological processes such as cell pro... Read more »
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Antibody
A TetR-family transcription factor regulates fatty acid metabolism ...
Published: April, 2019
Abstract: Fatty acid metabolism and its regulation are known to play important roles in bacteria and eukaryotes. By contrast, although certain archaea appear... Read more »
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IPure kit
Enabling cell-type-specific behavioral epigenetics in Drosophila: a...
Published: April, 2019
Abstract: BACKGROUND: Epigenetic mechanisms play fundamental roles in brain function and behavior and stressors such as social isolation can alter animal beh... Read more »
Assessment and site-specific manipulation of DNA (hydroxy-)methylat...
Published: April, 2019
Abstract: Dynamic changes in DNA (hydroxy-)methylation are fundamental for stem cell differentiation. However, the signature of these epigenetic marks in spe... Read more »
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MagMeDIP kit
The FZD7-TWIST1 axis is responsible for anoikis resistance and tumo...
Published: April, 2019
Abstract: Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD... Read more »
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Antibody
Mitochondrial stress triggers a pro-survival response through epige...
Published: April, 2019
Abstract: Mitochondrial dysfunction represents an important cellular stressor and when intense and persistent cells must unleash an adaptive response to prev... Read more »
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Premium RRBS Kit
Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Ph...
Published: April, 2019
Abstract: CAF-1 is an evolutionarily conserved H3/H4 histone chaperone that plays a key role in replication-coupled chromatin assembly and is targeted to the... Read more »
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Antibody
Kdm6b regulates context-dependent hematopoietic stem cell self-rene...
Published: April, 2019
Abstract: The histone demethylase KDM6B (JMJD3) is upregulated in blood disorders, suggesting that it may have important pathogenic functions. Here we examin... Read more »
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Antibody
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human ...
Published: March, 2019
Abstract: Expansion of transposable elements (TEs) coincides with evolutionary shifts in gene expression. TEs frequently harbor binding sites for transcripti... Read more »
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Antibody
Restriction-site associated DNA sequencing supports a sister group ...
Published: March, 2019
Abstract: The orchid genus Nigritella is closely related to Gymnadenia and has from time to time been merged with the latter. Although Nigritella is morpholo... Read more »
Biocompatible N-acetyl cysteine reduces graphene oxide and persists...
Published: March, 2019
Abstract: We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced ... Read more »
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Megaruptor
Point mutations in the PDX1 transactivation domain impair human β-c...
Published: March, 2019
Abstract: OBJECTIVE: Hundreds of missense mutations in the coding region of PDX1 exist; however, if these mutations predispose to diabetes mellitus is unknow... Read more »
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Antibody Microplex Library Preparation kit
H3K27M induces defective chromatin spread of PRC2-mediated repressi...
Published: March, 2019
Abstract: Lys-27-Met mutations in histone 3 genes (H3K27M) characterize a subgroup of deadly gliomas and decrease genome-wide H3K27 trimethylation. Here we u... Read more »
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IP-Star Compact iDeal ChIP-seq Kit for Histones
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transiti...
Published: March, 2019
Abstract: Humoral immunity depends on efficient activation of B cells and their subsequent differentiation into antibody-secreting cells (ASCs). The transcri... Read more »
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Bioruptor
TF-ChIP Method for Tissue-Specific Gene Targets.
Published: March, 2019
Abstract: Chromatin immunoprecipitation (ChIP) is an assay developed in order to define the dynamic nature of transcription processes. This method has been w... Read more »
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Bioruptor
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prost...
Published: March, 2019
Abstract: Androgen deprivation therapy for prostate cancer (PCa) benefits patients with early disease, but becomes ineffective as PCa progresses to a castrat... Read more »
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Antibody

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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