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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered ...
Published: June, 2019
Abstract: The deubiquitinating enzyme BAP1 is a tumor suppressor, among others involved in cholangiocarcinoma. BAP1 has many proposed molecular targets, whil... Read more »
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Antibody
Resveratrol up-regulates ATP2A3 gene expression in breast cancer ce...
Published: June, 2019
Abstract: Resveratrol (RSV) is a phytoestrogen which has been related to chemoprevention of several types of cancer. In this work, we show up to a 6-fold inc... Read more »
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OneDay ChIP Kit
DNA methylation of the Tacr2 gene in a CUMS model of depression.
Published: June, 2019
Abstract: Tacr2, the gene encoding the NK2 receptor, belongs to G protein-coupled receptors. Accumulating evidence has indicated that the tachykinin receptor... Read more »
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MagMeDIP kit
Characterization of the salmon louse Lepeophtheirus salmonis miRNom...
Published: June, 2019
Abstract: The salmon louse Lepeophtheirus salmonis is a marine ectoparasite that has a detrimental impact on salmon farms. Genomic knowledge of adult stages ... Read more »
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CATS
A chromosome-scale genome assembly of cucumber (Cucumis sativus L.).
Published: June, 2019
Abstract: BACKGROUND: Accurate and complete reference genome assemblies are fundamental for biological research. Cucumber is an important vegetable crop and ... Read more »
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Megaruptor
Twist2 amplification in rhabdomyosarcoma represses myogenesis and p...
Published: June, 2019
Abstract: Rhabdomyosarcoma (RMS) is an aggressive pediatric cancer composed of myoblast-like cells. Recently, we discovered a unique muscle progenitor marked... Read more »
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Antibody
Preformed chromatin topology assists transcriptional robustness of ...
Published: May, 2019
Abstract: Long-range gene regulation involves physical proximity between enhancers and promoters to generate precise patterns of gene expression in space and... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
NRG1 is a critical regulator of differentiation in TP63-driven squa...
Published: May, 2019
Abstract: Squamous cell carcinomas (SCCs) account for the majority of cancer mortalities. Although TP63 is an established lineage-survival oncogene in SCCs, ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Ep400 deficiency in Schwann cells causes persistent expression of e...
Published: May, 2019
Abstract: Schwann cells ensure efficient nerve impulse conduction in the peripheral nervous system. Their development is accompanied by defined chromatin cha... Read more »
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Antibody
Novel interactions between the HTLV-1 antisense protein HBZ and the...
Published: May, 2019
Abstract: The human T-cell leukemia virus type 1 (HTLV-1) regulatory proteins Tax and HBZ play indispensable roles in regulating viral and cellular gene expr... Read more »
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HighCell ChIP kit
The sncRNA Zoo: a repository for circulating small noncoding RNAs i...
Published: May, 2019
Abstract: The repertoire of small noncoding RNAs (sncRNAs), particularly miRNAs, in animals is considered to be evolutionarily conserved. Studies on sncRNAs ... Read more »
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CATS
Metabolic and Innate Immune Cues Merge into a Specific Inflammatory...
Published: May, 2019
Abstract: Innate immune responses are intricately linked with intracellular metabolism of myeloid cells. Toll-like receptor (TLR) stimulation shifts intracel... Read more »
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Master Mix
Life-Long AAV-Mediated CRISPR Genome Editing in Dystrophic Heart Im...
Published: May, 2019
Abstract: Previous studies from others and us have demonstrated that CRISPR genome editing could offer a promising therapeutic strategy to restore dystrophin... Read more »
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Antibody
Acetate Promotes T Cell Effector Function during Glucose Restriction.
Published: May, 2019
Abstract: Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic ... Read more »
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Antibody
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeut...
Published: May, 2019
Abstract: High-grade gliomas defined by histone 3 K27M driver mutations exhibit global loss of H3K27 trimethylation and reciprocal gain of H3K27 acetylation,... Read more »
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Antibody IP-Star Compact iDeal ChIP-seq Kit for Histones
BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Re...
Published: May, 2019
Abstract: Drug-tolerant "persister" tumor cells underlie emergence of drug-resistant clones and contribute to relapse and disease progression. Here we report... Read more »
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Antibody
The methylation pattern of DNA and complex correlations with gene e...
Published: May, 2019
Abstract: Chinese cabbage (Brassica rapa L. ssp. pekinensis) is one of the most important economic crops. However, its yield and quality can be severely thre... Read more »
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MagMeDIP kit
Genome Sequence and Methylation Patterns of sp. Strain BOL3-1, the...
Published: May, 2019
Abstract: sp. strain BOL3-1 was isolated from Salar de Uyuni, Bolivia, and sequenced using single-molecule real-time sequencing. Its 3.7-Mbp genome was analy... Read more »
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Megaruptor
Epigenetic Alterations in Juvenile Spondyloarthritis Patients: a Pr...
Published: May, 2019
Abstract: Juvenile spondyloarthritis (jSpA) is a complex disease with both genetic and environmental factors contributing to etiology. Multiple studies have ... Read more »
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MagMeDIP kit
Cardiac Reprogramming Factors Synergistically Activate Genome-wide ...
Published: May, 2019
Abstract: The cardiogenic transcription factors (TFs) Mef2c, Gata4, and Tbx5 can directly reprogram fibroblasts to induced cardiac-like myocytes (iCLMs), pre... Read more »
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Antibody
Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory i...
Published: May, 2019
Abstract: BACKGROUND: Rewriting of the epigenome has risen as a promising alternative to gene editing for precision medicine. In nature, epigenetic silencing... Read more »
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Antibody
Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Tra...
Published: May, 2019
Abstract: The gene regulatory network (GRN) of naive mouse embryonic stem cells (ESCs) must be reconfigured to enable lineage commitment. TCF3 sanctions rewi... Read more »
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Antibody
Guidelines for optimized gene knockout using CRISPR/Cas9
Published: May, 2019
Abstract: CRISPR/Cas9 technology has evolved as the most powerful approach to generate genetic models both for fundamental and preclinical research. Despite ... Read more »
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IP-Star Compact Microplex Library Preparation kit iDeal ChIP-seq Kit for Transcription Factors CRISPR
Interferon signature in patients with STAT1 gain-of-function mutati...
Published: May, 2019
Abstract: STAT1 gain-of-function (GOF) variants lead to defective Th17 cell development and chronic mucocutaneous candidiasis (CMC), but frequently also... Read more »
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IP-Star Compact
The Chromatin Factor HNI9 and ELONGATED HYPOCOTYL5 Maintain ROS Hom...
Published: May, 2019
Abstract: Reactive oxygen species (ROS) can accumulate in cells at excessive levels, leading to unbalanced redox states and to potential oxidative stress, wh... Read more »
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Antibody
Repression of Germline Genes in Somatic Tissues by H3K9 Dimethylat...
Published: May, 2019
Abstract: Repression of germline-promoting genes in somatic cells is critical for somatic development and function. To study how germline genes are repressed... Read more »
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IP-Star Compact
Long-range interactions between topologically associating domains s...
Published: May, 2019
Abstract: Genomic information is selectively used to direct spatial and temporal gene expression during differentiation. Interactions between topologically a... Read more »
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Antibody
Epigenetic control of the angiotensin-converting enzyme in endothel...
Published: May, 2019
Abstract: The angiotensin-converting enzyme (ACE) plays a central role in the renin-angiotensin system, which is involved in the regulation of blood pressure... Read more »
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MagMeDIP kit
Epigenetic modulation of a hardwired 3D chromatin landscape in two ...
Published: May, 2019
Abstract: The mechanisms underlying enhancer activation and the extent to which enhancer-promoter rewiring contributes to spatiotemporal gene expression are ... Read more »
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Antibody
Bromodomain inhibition of the coactivators CBP/EP300 facilitate cel...
Published: May, 2019
Abstract: Silencing of the somatic cell type-specific genes is a critical yet poorly understood step in reprogramming. To uncover pathways that maintain cell... Read more »
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Antibody

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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