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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Chromatin activity at GWAS loci identifies T cell states driving co...
Published: March, 2019
Abstract: Complex immune disease variants are enriched in active chromatin regions of T cells and macrophages. However, whether these variants function in sp... Read more »
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Bioruptor iDeal ChIP-seq Kit for Histones
MicroRNAs and Transplantation.
Published: March, 2019
Abstract: miRNAs, ∼20 to 22 nucleotide single-stranded RNA species that play a pivotal role in the regulation of protein-coding genes, are emerging as ro... Read more »
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CATS
NF-κB p65 dimerization and DNA-binding is important for inflammator...
Published: March, 2019
Abstract: Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-... Read more »
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Microplex Library Preparation kit
H3K27me3 is an epigenetic barrier while KDM6A overexpression improv...
Published: March, 2019
Abstract: Aberrant epigenetic reprogramming is a major factor of developmental failure of cloned embryos. Histone H3 lysine 27 trimethylation (H3K27me3), a h... Read more »
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Antibody
Long-term evaluation of AAV-CRISPR genome editing for Duchenne musc...
Published: March, 2019
Abstract: Duchenne muscular dystrophy (DMD) is a monogenic disorder and a candidate for therapeutic genome editing. There have been several recent reports of... Read more »
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CRISPR
One-step generation of modular CAR-T cells with AAV-Cpf1.
Published: March, 2019
Abstract: Immune-cell engineering opens new capabilities for fundamental immunology research and immunotherapy. We developed a system for efficient generatio... Read more »
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CRISPR
Genomewide analysis of 6-methyladenine DNA in peripheral blood mono...
Published: March, 2019
Abstract: AIM: The aim of this paper is to explore the expression of 6-methyladenine (6mA) DNA and to elucidate its gene regulation role in systemic lupus er... Read more »
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Antibody
The alternative reality of plant mitochondrial DNA
Published: March, 2019
Abstract: Plant mitochondrial genomes are usually assembled and displayed as circular maps based on the widely-held assumption that circular genome molecules... Read more »
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Megaruptor
Differential regulation of RNA polymerase III genes during liver re...
Published: February, 2019
Abstract: Mouse liver regeneration after partial hepatectomy involves cells in the remaining tissue synchronously entering the cell division cycle. We have u... Read more »
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Microplex Library Preparation kit
A critical but divergent role of PRDM14 in human primordial germ ce...
Published: February, 2019
Abstract: PRDM14 is a crucial regulator of mouse primordial germ cells (mPGC), epigenetic reprogramming and pluripotency, but its role in the evolutionarily ... Read more »
Environmental Toxicant Induced Epigenetic Transgenerational Inherit...
Published: February, 2019
Abstract: Prostate diseases include prostate cancer, which is the second most common male neoplasia, and benign prostatic hyperplasia (BPH), which affects ap... Read more »
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Antibody
CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoiet...
Published: February, 2019
Abstract: In this study, we demonstrate that, among all five CBX Polycomb proteins, only CBX7 possesses the ability to control self-renewal of human hematopo... Read more »
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Antibody Microplex Library Preparation kit
Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Mic...
Published: February, 2019
Abstract: The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However... Read more »
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Antibody
EZH2 is overexpressed in transitional preplasmablasts and is involv...
Published: February, 2019
Abstract: Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using m... Read more »
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Antibody IPure kit IP-Star Compact True MicroChIP kit iDeal ChIP-seq Kit for Transcription Factors
A cell cycle-coordinated Polymerase II transcription compartment en...
Published: February, 2019
Abstract: Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed until the mid-blastu... Read more »
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Antibody
Crosstalk Between Glucocorticoid Receptor and Early-growth Response...
Published: February, 2019
Abstract: The brain-derived neurotrophic factor (BDNF) is a key player in brain functions such as synaptic plasticity, stress, and behavior. Its gene structu... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Adolescent social isolation affects parvalbumin expression in the m...
Published: February, 2019
Abstract: Altered parvalbumin (PV) expression is observed in the prefrontal cortex of subjects with schizophrenia. Environmental context, particularly during... Read more »
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ChIP-qPCR
Developmental regulation of DNA cytosine methylation at the immunog...
Published: February, 2019
Abstract: DNA cytosine methylation is involved in the regulation of gene expression during development and its deregulation is often associated with disease.... Read more »
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Premium Bisulfite Kit
Interleukin-22 protects intestinal stem cells against genotoxic str...
Published: February, 2019
Abstract: Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from... Read more »
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Beads
Characterizing the Major Structural Variant Alleles of the Human Ge...
Published: January, 2019
Abstract: In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen... Read more »
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Megaruptor
Complete Genome Sequence and Methylome Analysis of Micrococcus lute...
Published: January, 2019
Abstract: Micrococcus luteus has been found in a wide range of habitats. We report the complete genome sequence and methylome analysis of strain SA211 isolat... Read more »
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Megaruptor
Replication timing and epigenome remodelling are associated with th...
Published: January, 2019
Abstract: DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and c... Read more »
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Antibody
Evidence of association of circulating epigenetic-sensitive biomark...
Published: January, 2019
Abstract: Circulating biomarkers available in clinical practice do not allow to stratify patients with coronary heart disease (CHD) prior the onset of a clin... Read more »
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MagMeDIP kit
Chromatin-Based Classification of Genetically Heterogeneous AMLs in...
Published: January, 2019
Abstract: Global investigation of histone marks in acute myeloid leukemia (AML) remains limited. Analyses of 38 AML samples through integrated transcriptiona... Read more »
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Antibody
CRISPR-mediated activation of a promoter or enhancer rescues obesit...
Published: January, 2019
Abstract: A wide range of human diseases result from haploinsufficiency, where the function of one of the two gene copies is lost. Here, we targeted the rema... Read more »
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CRISPR
High-throughput ChIPmentation: freely scalable, single day ChIPseq ...
Published: January, 2019
Abstract: BACKGROUND: Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor bin... Read more »
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Antibody
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Ep...
Published: January, 2019
Abstract: CD4 T helper (Th) differentiation is regulated by diverse inputs, including the vitamin A metabolite retinoic acid (RA). RA acts through its recept... Read more »
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Antibody
Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rha...
Published: January, 2019
Abstract: Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin remodeling complex, is the hallmark genetic aberration of atypical te... Read more »
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Antibody
Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Pro...
Published: January, 2019
Abstract: Adenosine deaminase associated with RNA1 (ADAR1) deregulation contributes to therapeutic resistance in many malignancies. Here we show that ADAR1-i... Read more »
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Antibody LowCell ChIP kit
Fluorescence-Activated Cell Sorting-Based Isolation and Characteriz...
Published: January, 2019
Abstract: Adult mammalian brain, including humans, has rather limited addition of new neurons and poor regenerative capacity. In contrast, neural stem cells ... Read more »
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Microplex Library Preparation kit

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