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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Increased H3K9 methylation and impaired expression of Protocadherin...
Published: June, 2018
Abstract: Kleefstra syndrome, a disease with intellectual disability, autism spectrum disorders and other developmental defects is caused in humans by haploi... Read more »
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Antibody
Histone H3 lysine 36 methyltransferase mobilizes NER factors to reg...
Published: June, 2018
Abstract: The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA d... Read more »
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Antibody
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: June, 2018
Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora of functio... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense...
Published: June, 2018
Abstract: BACKGROUND: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide m... Read more »
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HighCell ChIP kit
UTX-mediated enhancer and chromatin remodeling suppresses myeloid l...
Published: June, 2018
Abstract: The histone H3 Lys27-specific demethylase UTX (or KDM6A) is targeted by loss-of-function mutations in multiple cancers. Here, we demonstrate that U... Read more »
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Antibody
Estrogen receptor α dependent regulation of estrogen related recept...
Published: May, 2018
Abstract: BACKGROUND: Breast cancer (BC) is highly heterogeneous with ~ 60-70% of estrogen receptor positive BC patient's response to anti-hormone the... Read more »
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Antibody
The histone demethylase Phf2 acts as a molecular checkpoint to prev...
Published: May, 2018
Abstract: Aberrant histone methylation profile is reported to correlate with the development and progression of NAFLD during obesity. However, the identifica... Read more »
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Antibody
A Rapid and Robust Protocol for Reduced Representation Bisulfite Se...
Published: May, 2018
Abstract: Reduced representation bisulfite sequencing (RRBS) is one of the most comprehensive yet economic ways of mapping whole genome DNA-methylation. Here... Read more »
An improved assembly and annotation of the melon (Cucumis melo L.) ...
Published: May, 2018
Abstract: We report an improved assembly (v3.6.1) of the melon (Cucumis melo L.) genome and a new genome annotation (v4.0). The optical mapping approach allo... Read more »
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IPure kit IP-Star Compact
Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem...
Published: May, 2018
Abstract: The cell microenvironment, which is critical for stem cell maintenance, contains both cellular and non-cellular components, including sec... Read more »
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IP-Star Antibody True MicroChIP kit iDeal ChIP-seq Kit for Histones
Polycomb Repressive Complex 2 attenuates the very high expression o...
Published: May, 2018
Abstract: PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression... Read more »
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Antibody IPure kit
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: May, 2018
Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »
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Antibody
Distinct epigenetic landscapes underlie the pathobiology of pancrea...
Published: May, 2018
Abstract: Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although... Read more »
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Antibody
Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates...
Published: May, 2018
Abstract: Cell–cell and cell–matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, bu... Read more »
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Bioruptor H3K4me3 (C15410003) Bioruptor Plus
Insulin promoter in human pancreatic β cells contacts diabetes susc...
Published: May, 2018
Abstract: Both type 1 and type 2 diabetes involve a complex interplay between genetic, epigenetic, and environmental factors. Our laboratory has been interes... Read more »
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IP-Star Compact Microplex Library Preparation kit True MicroChIP kit
Functional interplay between E2F7 and ribosomal rRNA gene transcrip...
Published: May, 2018
Abstract: A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. ... Read more »
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Bioruptor
Local adaptation and ecological differentiation under selection, mi...
Published: May, 2018
Abstract: How the balance between selection, migration and drift influences the evolution of local adaptation has been under intense theoretical scrutiny. Ye... Read more »
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Bioruptor
The chromatin remodeling factor SPOC1 acts as a cellular restricti...
Published: May, 2018
Abstract: The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA dam... Read more »
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Bioruptor Bioruptor Plus
Modulation of gene transcription and epigenetics of colon carcinoma...
Published: May, 2018
Abstract: Interactions between bacteria and colon cancer cells influence the transcription of the host cell. Yet is it undetermined whether the bacteria itse... Read more »
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Microplex Library Preparation kit
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: May, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while lim...
Published: May, 2018
Abstract: GATA-binding protein 3 (GATA3) acts as the master transcription factor for type 2 T helper (Th2) cell differentiation and function. However, it is ... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones
A new metabolic gene signature in prostate cancer regulated by JMJD...
Published: May, 2018
Abstract: Histone methylation is essential for gene expression control. Trimethylated lysine 27 of histone 3 (H3K27me3) is controlled by the balance between ... Read more »
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Antibody IP-Star Compact True MicroChIP kit
Nuclear fate of yeast snoRNA is determined by co-transcriptional Rn...
Published: May, 2018
Abstract: Small nucleolar RNA (snoRNA) are conserved and essential non-coding RNA that are transcribed by RNA Polymerase II (Pol II). Two snoRNA classes, for... Read more »
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Bioruptor
The Ftx Noncoding Locus Controls X Chromosome Inactivation Independ...
Published: May, 2018
Abstract: Accumulation of the Xist long noncoding RNA (lncRNA) on one X chromosome is the trigger for X chromosome inactivation (XCI) in female mammals.... Read more »
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Antibody
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Mainta...
Published: May, 2018
Abstract: Hox genes modulate the properties of hematopoietic stem cells (HSCs) and reacquired Hox expression in progenitors contributes to leukemogenesis. He... Read more »
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True MicroChIP kit
SUN2 Modulates HIV-1 Infection and Latency through Association with...
Published: May, 2018
Abstract: The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV gen... Read more »
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Bioruptor
The novel BET bromodomain inhibitor BI 894999 represses super-enhan...
Published: May, 2018
Abstract: Bromodomain and extra-terminal (BET) protein inhibitors have been reported as treatment options for acute myeloid leukemia (AML) in preclinical mod... Read more »
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Antibody
Viral targeting of TFIIB impairs de novo polymerase II recruitment ...
Published: April, 2018
Abstract: Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regula... Read more »
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Bioruptor Bioruptor Plus
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: April, 2018
Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »
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Bioruptor Bioruptor Plus

イベント

  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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