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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Integrative omics data analyses of repeated dose toxicity of valpro...
Published: January, 2018
Abstract: Valproic acid (VPA) is a very potent anti-cancer and neuro-protective drug probably by its HDAC inhibiting properties, which may cause steatosis in... Read more »
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MagMeDIP kit
BCG Educates Hematopoietic Stem Cells to Generate Protective Innate...
Published: January, 2018
Abstract: The dogma that adaptive immunity is the only arm of the immune response with memory capacity has been recently challenged by several studies demons... Read more »
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Microplex Library Preparation kit
Metabolic Induction of Trained Immunity through the Mevalonate Path...
Published: January, 2018
Abstract: Innate immune cells can develop long-term memory after stimulation by microbial products during infections or vaccinations. Here, we report that me... Read more »
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Antibody
BCG Vaccination Protects against Experimental Viral Infection in Hu...
Published: January, 2018
Abstract: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) has heterologous beneficial effects against non-related infections. The basis of the... Read more »
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Antibody
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain o...
Published: January, 2018
Abstract: Sirtuins are NAD+-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulate... Read more »
A novel long noncoding RNA LINC00844 regulates prostate cancer cell...
Published: January, 2018
Abstract: The majority of the human genome is transcribed, yielding a rich repository of non-coding transcripts that are involved in a myriad of biological p... Read more »
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Bioruptor
Senescence-associated reprogramming promotes cancer stemness.
Published: January, 2018
Abstract: Cellular senescence is a stress-responsive cell-cycle arrest program that terminates the further expansion of (pre-)malignant cells. Key signalling... Read more »
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Antibody
APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC ...
Published: January, 2018
Abstract: To date, epimutations reported in man have been somatic and erased in germlines. Here, we identify a cause of the autosomal recessive cblC class of... Read more »
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IP-Star Histone ChIP kit
Copper induces expression and methylation changes of early developm...
Published: January, 2018
Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »
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MagMeDIP kit
STAT5BN642H is a driver mutation for T cell neoplasia
Published: January, 2018
Abstract: STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and... Read more »
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Antibody
Genome-wide analysis of day/night DNA methylation differences in Po...
Published: January, 2018
Abstract: DNA methylation is an important mechanism of epigenetic modification. Methylation changes during stress responses and developmental processes have ... Read more »
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MagMeDIP kit Antibody
Obligatory and facilitative allelic variation in the DNA methylome ...
Published: January, 2018
Abstract: Integrating epigenetic data with genome-wide association study (GWAS) results can reveal disease mechanisms. The genome sequence itself also&n... Read more »
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MagMeDIP kit Antibody
MLL2 conveys transcription-independent H3K4 trimethylation in oocytes
Published: January, 2018
Abstract: Histone 3 K4 trimethylation (depositing H3K4me3 marks) is typically associated with active promoters yet paradoxically occurs at untranscribed doma... Read more »
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Antibody Microplex Library Preparation kit
TBR2 antagonizes retinoic acid dependent neuronal differentiation b...
Published: January, 2018
Abstract: During cerebral cortex development, neural progenitors are required to elaborate a variety of cell differentiation signals to which they are contin... Read more »
Chromatin Immunoprecipitation Assay in the Hyperthermoacidophilic C...
Published: January, 2018
Abstract: Chromatin immunoprecipitation (ChIP) is a powerful method used for identifying genome-wide DNA-protein interactions in vivo. A large number of esse... Read more »
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IPure kit
Detection of Hermetia illucens by real-time PCR
Published: January, 2018
Abstract: Insects are rich in proteins and could be an alternative source of macronutrients to feed animals and humans. Over the past few years, numerous com... Read more »
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Master Mix
Antioxydation And Cell Migration Genes Are Identified as Potential ...
Published: January, 2018
Abstract: Basal-like breast cancers are among the most aggressive cancers and effective targeted therapies are still missing. In order to identify new therap... Read more »
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MethylCap
Impact of Lactobacillus plantarum ST-III on the composition of infa...
Published: January, 2018
Abstract: Several studies have demonstrated the effect of probiotics on prevention of diseases in infants. However, the mechanisms remain not fully addressed... Read more »
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Master Mix
RNA-Based dCas9–VP64 System Improves the Viability of Cryopreserved...
Published: January, 2018
Abstract: Regenerative therapies require availability of an abundant healthy cell source which can be achieved by e±cient cryopreservation techniques.... Read more »
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Antibody CRISPR
Epigenetic alterations in TRAMP mice: epigenome DNA methylation pro...
Published: January, 2018
Abstract: Purpose: We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer m... Read more »
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MagMeDIP kit
Environmental toxicant induced epigenetic transgenerational inherit...
Published: January, 2018
Abstract: Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Sy... Read more »
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Antibody
Cancer cell specific inhibition of Wnt/β-catenin signaling by force...
Published: January, 2018
Abstract: Use of the diabetes type II drug Metformin is associated with a moderately lowered risk of cancer incidence in numerous tumor entities. Studying th... Read more »
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Antibody
Neonatal exposure to hyperoxia leads to persistent disturbances in ...
Published: January, 2018
Abstract: Background: Early pulmonary oxygen exposure is one of the most important factors implicated in the development of bronchopulmonary dysplasia (BPD).... Read more »
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Antibody
Analysis of DNA methylome and transcriptome profiling following Gib...
Published: January, 2018
Abstract: The present work investigated a comprehensive genome-wide landscape of DNA methylome and its relationship with transcriptome upon gibberellin A3 (G... Read more »
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MagMeDIP kit Antibody
Isl1 mediates mesenchymal expansion in the developing external geni...
Published: January, 2018
Abstract: Genital malformations are among the most common human birth defects, and both genetic and environmental factors can contribute to these malformatio... Read more »
BRACHYURY directs histone acetylation to target loci during mesoder...
Published: January, 2018
Abstract: T-box transcription factors play essential roles in multiple aspects of vertebrate development. Here, we show that cooperative function of BRACHYUR... Read more »
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Antibody
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: December, 2017
Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »
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Bioruptor ChIP-seq
(Po)STAC (Polycistronic SunTAg modified CRISPR) enables live-cell a...
Published: December, 2017
Abstract: CRISPR/dCas9-based labeling has allowed direct visualization of genomic regions in living cells. However, poor labeling efficiency and signal-to-ba... Read more »
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Antibody
Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest ...
Published: December, 2017
Abstract: Cockayne syndrome (CS) is caused by mutations in CSA and CSB. The CSA and CSB proteins have been linked to both promoting transcription-coupled rep... Read more »
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Antibody
The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome...
Published: December, 2017
Abstract: Therapeutic intervention is an important need in ameliorating the severe consequences of Rett Syndrome (RTT), a neurological disorder caused by mut... Read more »
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Antibody

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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