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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A quantitative mass spectrometry-based approach to monitor the dyna...
Published: June, 2018
Abstract: Understanding the dynamics of endogenous protein-protein interactions in complex networks is pivotal in deciphering disease mechanisms. To enable t... Read more »
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Antibody
Replication-coupled histone H3.1 deposition determines nucleosome c...
Published: June, 2018
Abstract: Developmental phase transitions are often characterized by changes in the chromatin landscape and heterochromatin reorganization. In Arabidopsis, c... Read more »
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LowCell ChIP kit
Genome-wide rules of nucleosome phasing
Published: June, 2018
Abstract: Regular successions of positioned nucleosomes – phased nucleosome arrays (PNAs) – are predominantly known from transcriptional start si... Read more »
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Microplex Library Preparation kit
Modulation of vitamin D signaling by the pioneer factor CEBPA.
Published: June, 2018
Abstract: The myeloid master regulator CCAAT enhancer-binding protein alpha (CEBPA) is known as a pioneer factor. In this study, we report the CEBPA cistrome... Read more »
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Antibody
27nt-RNAs guide histone variant deposition via 'RNA-induced DNA rep...
Published: June, 2018
Abstract: BACKGROUND: During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby,... Read more »
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Beads
The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and F...
Published: June, 2018
Abstract: Synovial sarcoma (SS) is defined by the hallmark SS18-SSX fusion oncoprotein, which renders BAF complexes aberrant in two manners: gain of SSX to t... Read more »
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Antibody
A high-quality genome sequence of Rosa chinensis to elucidate ornam...
Published: June, 2018
Abstract: Rose is the world's most important ornamental plant, with economic, cultural and symbolic value. Roses are cultivated worldwide and sold as garden ... Read more »
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Megaruptor
MeDIP combined with in-solution targeted enrichment followed by NGS...
Published: June, 2018
Abstract: DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invas... Read more »
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iDeal Library Preparation Kit
Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB coop...
Published: June, 2018
Abstract: In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), pro... Read more »
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Antibody
Determination of the presence of 5-methylcytosine in Paramecium tet...
Published: June, 2018
Abstract: 5-methylcytosine DNA methylation regulates gene expression and developmental programming in a broad range of eukaryotes. However, its presence and ... Read more »
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Antibody
SETBP1 induces transcription of a network of development genes by a...
Published: June, 2018
Abstract: SETBP1 variants occur as somatic mutations in several hematological malignancies such as atypical chronic myeloid leukemia and as de novo germline ... Read more »
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Antibody
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedif...
Published: June, 2018
Abstract: To date, it remains largely unclear to what extent chromatin machinery contributes to the susceptibility and progression of complex diseases. Here,... Read more »
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Antibody
DNA Methylation and Regulatory Elements during Chicken Germline Ste...
Published: June, 2018
Abstract: The production of germ cells in vitro would open important new avenues for stem biology and human medicine, but the mechanisms of germ cell di... Read more »
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MethylCap
Immunity drives regulation in cancer through NF-κB.
Published: June, 2018
Abstract: Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to... Read more »
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Antibody
Immunity drives TET1 regulation in cancer through NF-kB
Published: June, 2018
Abstract: Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to... Read more »
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Antibody
The reference epigenome and regulatory chromatin landscape of chron...
Published: June, 2018
Abstract: Chronic lymphocytic leukemia (CLL) is a frequent hematological neoplasm in which underlying epigenetic alterations are only partially understood. H... Read more »
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Antibody
Epigenetic regulation of vascular NADPH oxidase expression and reac...
Published: June, 2018
Abstract: Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in... Read more »
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Antibody
Involvement of Epigenetic Modifications of GABAergic Interneurons i...
Published: June, 2018
Abstract: Background: Prenatal stress is considered a risk factor for anxiety disorder. Downregulation in the expression of GABAergic gene, that is, glutamic... Read more »
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MeDIP kit
Increased H3K9 methylation and impaired expression of Protocadherin...
Published: June, 2018
Abstract: Kleefstra syndrome, a disease with intellectual disability, autism spectrum disorders and other developmental defects is caused in humans by haploi... Read more »
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Antibody
Histone H3 lysine 36 methyltransferase mobilizes NER factors to reg...
Published: June, 2018
Abstract: The Set2 methyltransferase and its target, histone H3 lysine 36 (H3K36), affect chromatin architecture during the transcription and repair of DNA d... Read more »
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Antibody
Pro-inflammatory cytokine and high doses of ionizing radiation have...
Published: June, 2018
Abstract: The NF-κB transcription factors are activated via diverse molecular mechanisms in response to various types of stimuli. A plethora of functio... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense...
Published: June, 2018
Abstract: BACKGROUND: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide m... Read more »
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HighCell ChIP kit
UTX-mediated enhancer and chromatin remodeling suppresses myeloid l...
Published: June, 2018
Abstract: The histone H3 Lys27-specific demethylase UTX (or KDM6A) is targeted by loss-of-function mutations in multiple cancers. Here, we demonstrate that U... Read more »
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Antibody
Estrogen receptor α dependent regulation of estrogen related recept...
Published: May, 2018
Abstract: BACKGROUND: Breast cancer (BC) is highly heterogeneous with ~ 60-70% of estrogen receptor positive BC patient's response to anti-hormone the... Read more »
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Antibody
The histone demethylase Phf2 acts as a molecular checkpoint to prev...
Published: May, 2018
Abstract: Aberrant histone methylation profile is reported to correlate with the development and progression of NAFLD during obesity. However, the identifica... Read more »
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Antibody
A Rapid and Robust Protocol for Reduced Representation Bisulfite Se...
Published: May, 2018
Abstract: Reduced representation bisulfite sequencing (RRBS) is one of the most comprehensive yet economic ways of mapping whole genome DNA-methylation. Here... Read more »
An improved assembly and annotation of the melon (Cucumis melo L.) ...
Published: May, 2018
Abstract: We report an improved assembly (v3.6.1) of the melon (Cucumis melo L.) genome and a new genome annotation (v4.0). The optical mapping approach allo... Read more »
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IPure kit IP-Star Compact
Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem...
Published: May, 2018
Abstract: The cell microenvironment, which is critical for stem cell maintenance, contains both cellular and non-cellular components, including sec... Read more »
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IP-Star Antibody True MicroChIP kit iDeal ChIP-seq Kit for Histones
Polycomb Repressive Complex 2 attenuates the very high expression o...
Published: May, 2018
Abstract: PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression... Read more »
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Antibody IPure kit
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and ...
Published: May, 2018
Abstract: Processes like cellular senescence are characterized by complex events giving rise to heterogeneous cell populations. However, the early molecular ... Read more »
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Antibody

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