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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The Polycomb Group Gene EMF2B is essential for maintenance of flora...
Published: October, 2014
Abstract: The Polycomb Repressive Complex 2 (PRC2) represses transcriptional activity of target genes through trimethylation of Lysine 27 of Histone H3. The ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa an...
Published: October, 2014
Abstract: Obesity contributes to the development of non‑alcoholic fatty liver disease (NAFLD), which is characterized by the upregulated expression of two ke... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003) Bioruptor Plus
Altered promoter nucleosome positioning is an early event in gene s...
Published: October, 2014
Abstract: Gene silencing in cancer frequently involves hypermethylation and dense nucleosome occupancy across promoter regions. How a promoter transitions to... Read more »
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DNA shearing Bioruptor
SOX11 promotes tumor angiogenesis through transcriptional regulatio...
Published: October, 2014
Abstract: SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). We have recently proven that SO... Read more »
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Bioruptor Chromatin Shearing HighCell ChIP kit IPure kit
Integrator Regulates Transcriptional Initiation and Pause Release f...
Published: October, 2014
Abstract: In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organisms, the transition from initiation to productiv... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Active and passive demethylation of male and female pronuclear DNA ...
Published: October, 2014
Abstract: The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embr... Read more »
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Antibody
Predicting interactome networks perturbations in human cancer: appl...
Published: October, 2014
Abstract: Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagn... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Hairy root transformation using Agrobacterium rhizogenes as a tool ...
Published: October, 2014
Abstract: Agrobacterium rhizogenes (or Rhizobium rhizogenes) is able to transform plant genomes and induce the production of hairy roots. We describe the use... Read more »
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Bioruptor Chromatin Shearing
Autophagy Controls BCG-Induced Trained Immunity and the Response to...
Published: October, 2014
Abstract: The anti-tuberculosis-vaccine Bacillus Calmette-Guérin (BCG) is the most widely used vaccine in the world. In addition to its effects against tuber... Read more »
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Antibody
The PML-associated protein DEK regulates the balance of H3.3 loadin...
Published: October, 2014
Abstract: Histone variant H3.3 is deposited in chromatin at active sites, telomeres, and pericentric heterochromatin by distinct chaperones, but the mechanis... Read more »
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Bioruptor Chromatin Shearing Antibody
Epigenetic mechanisms regulate placental c-myc and hTERT in normal ...
Published: October, 2014
Abstract: Placental development is known for its resemblance with tumor development, such as in the expression of oncogenes (c-myc) and telomerase (hTERT). T... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A NOTCH1-driven MYC enhancer promotes T cell development, transform...
Published: October, 2014
Abstract: Efforts to identify and annotate cancer driver genetic lesions have been focused primarily on the analysis of protein-coding genes; however, most g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Head formation: OTX2 regulates Dkk1 and Lhx1 activity in the anteri...
Published: October, 2014
Abstract: The Otx2 gene encodes a paired-type homeobox transcription factor that is essential for the induction and the patterning of the anterior structures... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide mapping of yeast histone chaperone anti-silencing funct...
Published: September, 2014
Abstract: Genome-wide participation and importance of the histone chaperone Asf1 (Anti-Silencing Function 1) in diverse DNA transactions like replication, re... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
c-Rel Regulates Ezh2 Expression in Activated Lymphocytes and Malign...
Published: September, 2014
Abstract: The Polycomb group protein Ezh2 is a histone methyltransferase that modifies chromatin structure to alter gene expression during embryonic developm... Read more »
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Bioruptor
Co-regulated expression of Na+/phosphate Pho89 transporter and Ena1...
Published: September, 2014
Abstract: The yeast Saccharomyces cerevisiae has two main high-affinity inorganic phosphate (Pi) transporters, Pho84 and Pho89, functionally relevant at acid... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq Bioruptor Plus
Retrotransposon-based profiling of mammalian epigenomes: DNA methyl...
Published: September, 2014
Abstract: In the current study, we have used HT-TREBS to individually analyze the DNA methylation pattern of 4799 IAP LTR retrotransposons in embryonic stem,... Read more »
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DNA shearing Bioruptor
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 a...
Published: September, 2014
Abstract: Throughout evolution primate genomes have been modified by waves of retrotransposon insertions. For each wave, the host eventually finds a way to r... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The specific alteration of histone methylation profiles by DZNep du...
Published: September, 2014
Abstract: Early embryo development constitutes a unique opportunity to study acquisition of epigenetic marks, including histone methylation. This study inves... Read more »
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Antibody
Co-detection and sequencing of genes and transcripts from the same ...
Published: September, 2014
Abstract: Despite the recent advance of single-cell gene expression analyses, co-measurement of both genomic and transcriptional signatures at the single-cel... Read more »
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DNA shearing Bioruptor
Significance of glioma-associated oncogene homolog 1 (GLI1) express...
Published: September, 2014
Abstract: IntroductionThe recently identified claudin-low subtype of breast cancer is enriched for cells with stem-like and mesenchymal-like characteristics.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Vitamin d receptor-mediated stromal reprogramming suppresses pancre...
Published: September, 2014
Abstract: The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) is attributed to intrinsic chemoresistance and a growth-permissive tumor microe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
SET8 methyltransferase activity during the DNA double-strand break ...
Published: September, 2014
Abstract: DNA double-strand breaks (DSBs) activate a signaling pathway known as the DNA damage response (DDR) which via protein–protein interactions and post... Read more »
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Antibody
Transducin-like enhancer of split 3 (TLE3) in adipose tissue is inc...
Published: September, 2014
Abstract: Transgenic overexpression of adipose tissue (AT) transducin-like enhancer of split 3 (TLE3) mimicked peroxisome proliferator-activated receptor gam... Read more »
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Master Mix
Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediate...
Published: September, 2014
Abstract: Depression is a debilitating condition with a profound impact on quality of life for millions of people worldwide. Physical exercise is used as a t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Tra...
Published: September, 2014
Abstract: In mammals, cytosine methylation (5mC) is widely distributed throughout the genome but is notably depleted from active promoters and enhancers. Whi... Read more »
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DNA shearing Bioruptor
Dysregulation of genome-wide gene expression and DNA methylation in...
Published: September, 2014
Abstract: BACKGROUND: Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development fa... Read more »
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MagMeDIP kit
Evidence that breast cancer risk at the 2q35 locus is mediated thro...
Published: September, 2014
Abstract: GWAS have identified a breast cancer susceptibility locus on 2q35. Here we report the fine mapping of this locus using data from 101,943 subjects f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
NF-κB Transcriptional Activity Is Modulated by FK506-binding Protei...
Published: September, 2014
Abstract: Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to... Read more »
Epigenetic events determine tissue-specific toxicity of inhalationa...
Published: September, 2014
Abstract: 1,3-Butadiene (BD), a widely used industrial chemical and a ubiquitous environmental pollutant, is a known human carcinogen. Although genotoxicity ... Read more »
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DNA shearing

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