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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Heat shock factor 2 is a stress-responsive mediator of neuronal mig...
Published: July, 2014
Abstract: Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development de... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis...
Published: July, 2014
Abstract: Bone disease, characterized by the presence of lytic lesions and osteoporosis is the hallmark of multiple myeloma (MM). Stromal cell-derived factor... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
K-Lysine acetyltransferase 2a regulates a hippocampal gene expressi...
Published: July, 2014
Abstract: Neuronal histone acetylation has been linked to memory consolidation, and targeting histone acetylation has emerged as a promising therapeutic stra... Read more »
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LowCell ChIP kit
IGF2BP1 Expression in Human Mesenchymal Stem Cells Significantly Af...
Published: July, 2014
Abstract: Mesenchymal stem cells (MSCs) are a population of cells harboring in many tissues with the ability to differentiate toward many different lineages.... Read more »
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MeDIP kit
Genome-wide association analysis of eosinophilic esophagitis provid...
Published: July, 2014
Abstract: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder associated with allergic hypersensitivity to food. We interrogated >1.5 millio... Read more »
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IP-Star IP-Star Compact
Screening and identification of small molecule inhibitors of ErbB2-...
Published: July, 2014
Abstract: ERBB2 amplification and overexpression are strongly associated with invasive cancer with high recurrence and poor prognosis. Enhanced ErbB2 signali... Read more »
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Bioruptor Cell Lysis
Comparative genome sequencing reveals chemotype-specific gene clust...
Published: July, 2014
Abstract: Background The fungal genus Stachybotrys produces several diverse toxins that affect human health. Its strains comprise two mutually-exclusive tox... Read more »
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DNA shearing Bioruptor
Paradoxical role of DNA methylation in activation of FoxA2 gene exp...
Published: July, 2014
Abstract: The transcription factor FoxA2 is a master regulator of endoderm development and pancreatic beta cell gene expression. To elucidate the mechanisms ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Microsatellite Primers for the Fungi Rhizopogon kretzerae and R. sa...
Published: July, 2014
Abstract: PREMISE OF THE STUDY: Rhizopogon kretzerae and R. salebrosus (Rhizopogonaceae) are ectomycorrhizal fungi symbiotic with pines and the mycoheterotr... Read more »
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DNA shearing Bioruptor
Noncoding Transcription by Alternative RNA Polymerases Dynamically ...
Published: July, 2014
Abstract: The eukaryotic epigenome is shaped by the genome topology in three-dimensional space. Dynamic reversible variations in this epigenome structure dir... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star Bioruptor Plus IPure kit IP-Star Compact
Non-Circadian Expression Masking Clock-Driven Weak Transcription Rh...
Published: July, 2014
Abstract: U2OS cells harbor a circadian clock but express only a few rhythmic genes in constant conditions. We identified 3040 binding sites of the circadian... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Very small deletions within the NESP55 gene in pseudohypoparathyroi...
Published: July, 2014
Abstract: Pseudohypoparathyroidism (PHP) is caused by reduced expression of genes within the GNAS cluster, resulting in parathormone resistance. The cluster ... Read more »
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DNA shearing Bioruptor
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Published: July, 2014
Abstract: Mutations in the RNA-binding protein FUS have been shown to cause the neurodegenerative disease amyotrophic lateral sclerosis. We investigate wheth... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
bPeaks: a bioinformatics tool to detect transcription factor bindin...
Published: July, 2014
Abstract: Peak calling is a critical step in ChIPseq data analysis. Choosing the correct algorithm as well as optimized parameters for a specific biological ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Maintenance and replication of the human cytomegalovirus genome dur...
Published: July, 2014
Abstract: Human cytomegalovirus (HCMV) can establish latent infection in hematopoietic progenitor cells (HPCs) or CD14 (+) monocytes. While circularized vira... Read more »
Comparison of five different RNA sources to examine the lactating b...
Published: July, 2014
Abstract: The objective of this study was to examine five different sources of RNA, namely mammary gland tissue (MGT), milk somatic cells (SC), laser microdi... Read more »
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DNA shearing Bioruptor
Four methods of preparing mRNA 5' end libraries using the illumina ...
Published: July, 2014
Abstract: BACKGROUND: The 5' untranslated regions of mRNA play an important role in their translation. RESULTS: Here, we describe the development of four m... Read more »
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DNA shearing Bioruptor
Transcriptional regulation of LUX by CBF1 mediates cold input to th...
Published: July, 2014
Abstract: Circadian clocks allow organisms to anticipate daily changes in the environment to enhance overall fitness. Transcription factors (TFs) play a prom... Read more »
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Bioruptor Chromatin Shearing Bioruptor Plus
Epigenomic analysis of primary human T cells reveals enhancers asso...
Published: July, 2014
Abstract: A characteristic feature of asthma is the aberrant accumulation, differentiation or function of memory CD4(+) T cells that produce type 2 cytokines... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Histone Variant H2A.W Defines Heterochromatin and Promotes Chro...
Published: July, 2014
Abstract: Histone variants play crucial roles in gene expression, genome integrity, and chromosome segregation. We report that the four H2A variants in Arabi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Helicobacter pylori-induced STAT3 activation and signalling network...
Published: July, 2014
Abstract: Background: Helicobacter pylori (H. pylori) is the most important gastric carcinogen. However, the mechanisms of H. pylori induced gastric carcinog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ectopic DNMT3L triggers assembly of a repressive complex for retrov...
Published: July, 2014
Abstract: Mammalian genomes are replete with retrotransposable elements, including endogenous retroviruses. DNA methyltransferase 3-like (DNMT3L) is an epige... Read more »
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LowCell ChIP kit
Tissue specific insulator function at H19/Igf2 revealed by deletion...
Published: July, 2014
Abstract: Parent-of-origin specific expression at imprinted genes is regulated by allele-specific DNA methylation at imprinting control regions (ICRs). This ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gl...
Published: July, 2014
Abstract: Exposure to environmental estrogens (xenoestrogens) may play a causal role in the increased breast cancer incidence which has been observed in Euro... Read more »
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Antibody
Synergistic apoptosis in head and neck squamous cell carcinoma cell...
Published: July, 2014
Abstract: Background: In head and neck squamous cell carcinoma (HNSCC), resistance to single agent targeted therapy may be overcome by co-targeting of compen... Read more »
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Bioruptor Cell Lysis Western Blot
The interaction of MYC with the trithorax protein ASH2L promotes ge...
Published: July, 2014
Abstract: The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Identification of a large protein network involved in epigenetic tr...
Published: July, 2014
Abstract: Pluripotency of embryonic stem cells (ESCs) is maintained by transcriptional activities and chromatin modifying complexes highly organized within t... Read more »
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Bioruptor Chromatin Shearing Antibody H3K4me3 (C15410003)
The telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p ...
Published: July, 2014
Abstract: We provide evidence that a central player in ribosome synthesis, the ribonucleic acid helicase Prp43p, can be activated by yeast Gno1p and its huma... Read more »
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Bioruptor Cell Lysis
TET1 is a maintenance DNA demethylase that prevents methylation spr...
Published: July, 2014
Abstract: TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the preci... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Leishmania donovani chaperone cyclophilin 40 is essential for i...
Published: July, 2014
Abstract: During its life cycle, the protozoan pathogen Leishmania donovani is exposed to contrasting environments inside insect vector and vertebrate host, ... Read more »
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Bioruptor Cell Lysis

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  • FASEB Biological Methylation: Fundamental Mechanisms
    Porto, Portugal
    Jul 28-Aug 1, 2024
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