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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Asparagine synthetase deficiency detected by whole exome sequencing...
Published: September, 2014
Abstract: Deficiency of Asparagine Synthetase (ASNSD, MIM 615574) is a very rare autosomal recessive disorder presenting with some brain abnormalities. Affec... Read more »
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DNA shearing Bioruptor
Measuring fast gene dynamics in single cells with timelapse lumines...
Published: September, 2014
Abstract: Timelapse fluorescence microscopy is an important tool for measuring in vivo gene dynamics in single cells. However, fluorescent proteins are limit... Read more »
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Bioruptor
Genome-wide map of regulatory interactions in the human genome.
Published: September, 2014
Abstract: Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. We generat... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
SNAIL1 combines competitive displacement of ASCL2 and epigenetic me...
Published: September, 2014
Abstract: EPHB3 is a critical cellular guidance factor in the intestinal epithelium and an important tumor suppressor in colorectal cancer (CRC) whose expres... Read more »
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Bioruptor Chromatin Shearing Antibody Bioruptor Plus
Genome-wide CNV analysis in 221 unrelated patients and targeted hig...
Published: September, 2014
Abstract: To uncover novel causative genes in patients with unexplained adenomatous polyposis, a model disease for colorectal cancer, we performed a genome-w... Read more »
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DNA shearing Bioruptor
Spontaneous sleep-wake cycle and sleep deprivation differently indu...
Published: September, 2014
Abstract: Brain-derived neurotrophic factor (Bdnf) regulates neuronal plasticity, slow wave activity and sleep homeostasis. Environmental stimuli control Bdn... Read more »
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Antibody 5mC (C15200081)
6-methoxyflavone inhibits NFAT translocation into the nucleus and s...
Published: September, 2014
Abstract: NFAT plays a crucial role in the immune system by regulating the transcription of inducible genes during immune responses. In T cells, NFAT protein... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induce...
Published: September, 2014
Abstract: AIMS: Ultraviolet irradiation and carcinogens have been reported to induce epigenetic alterations, which potentially contribute to the development ... Read more »
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MagMeDIP kit
TELP, a sensitive and versatile library construction method for nex...
Published: September, 2014
Abstract: Next-generation sequencing has been widely used for the genome-wide profiling of histone modifications, transcription factor binding and gene expre... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Comparison of TALE designer transcription factors and the CRISPR/dC...
Published: September, 2014
Abstract: The transcription activator-like effectors (TALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat (CRISPR) associated ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Shigella flexneri targets the HP1γ subcode through the phosphothreo...
Published: September, 2014
Abstract: HP1 proteins are transcriptional regulators that, like histones, are targets for post-translational modifications defining an HP1-mediated subcode.... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The DEK oncoprotein binds to highly and ubiquitously expressed gene...
Published: September, 2014
Abstract: BACKGROUND: The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. Whil... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Up to date sample preparation of proteins for mass spectrometric an...
Published: September, 2014
Abstract: Abstract For the identification of proteins from biological samples by mass spectrometry there are two scenarios. Proteins are pre-fractionated in ... Read more »
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Bioruptor Tissue Homogenization
Target enrichment of ultraconserved elements from arthropods provid...
Published: September, 2014
Abstract: Gaining a genomic perspective on phylogeny requires the collection of data from many putatively independent loci across the genome. Among insects, ... Read more »
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DNA shearing Bioruptor
Neural stem cell differentiation is dictated by distinct actions of...
Published: September, 2014
Abstract: Signaling factors including retinoic acid (RA) and thyroid hormone (T3) promote neuronal, oligodendrocyte, and astrocyte differentiation of cortica... Read more »
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Bioruptor Chromatin Shearing ChIP-seq HighCell ChIP kit
Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphoc...
Published: September, 2014
Abstract: BackgroundIdentification of novel genetic risk factors is imperative for a better understanding of B lymphomagenesis and for the development of nov... Read more »
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Antibody
NKCC1 mediates traumatic brain injury-induced hippocampal neurogene...
Published: September, 2014
Abstract: Traumatic brain injury (TBI) is one of the most prevalent causes of worldwide mortality and morbidity. We previously had evidenced that TBI induced... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
PDYN, a gene implicated in brain/mental disorders, is targeted by R...
Published: September, 2014
Abstract: The dynorphin κ-opioid receptor system is implicated in mental health and brain/mental disorders. However, despite accumulating evidence that PDYN ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
PaperClip: rapid multi-part DNA assembly from existing libraries.
Published: September, 2014
Abstract: Assembly of DNA 'parts' to create larger constructs is an essential enabling technique for bioengineering and synthetic biology. Here we describe a... Read more »
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Bioruptor Cell Lysis
Chromatin immunoprecipitation for human monocyte derived macrophages.
Published: September, 2014
Abstract: The importance of Chromatin Immunoprecipitation (ChIP) technology has grown exponentially along with an increased interest in epigenetic regulation... Read more »
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis t...
Published: September, 2014
Abstract: Wilms tumour is the most common childhood kidney cancer. Here we report the whole-exome sequencing of 44 Wilms tumours, identifying missense mutati... Read more »
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Bioruptor Cell Lysis
The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-depend...
Published: September, 2014
Abstract: The retinoblastoma gene, rb, ensures at least its tumor suppressor function by inhibiting cell proliferation. Its role in apoptosis is more complex... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit
Identification of a Face Enhancer Reveals Direct Regulation of LIM ...
Published: September, 2014
Abstract: Development of the mammalian face requires a large number of genes that are expressed with spatio-temporal specificity, and transcriptional regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprog...
Published: September, 2014
Abstract: Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesi... Read more »
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Bioruptor
Histone-fold domain protein NF-Y promotes chromatin accessibility f...
Published: September, 2014
Abstract: Cell type-specific master transcription factors (TFs) play vital roles in defining cell identity and function. However, the roles ubiquitous factor... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Western Blot
Determinants of G quadruplex-induced epigenetic instability in REV1...
Published: September, 2014
Abstract: REV1-deficient chicken DT40 cells are compromised in replicating G quadruplex (G4)-forming DNA. This results in localised, stochastic loss of paren... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Pcgf6, a polycomb group protein, regulates mesodermal lineage diffe...
Published: September, 2014
Abstract: Polycomb group (PcG) proteins comprise evolutionary conserved factors with essential functions for embryonic development and adult stem cells. PcG ... Read more »
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Antibody
Pregnane X receptor activation and silencing promote steatosis of h...
Published: September, 2014
Abstract: In addition to its well-characterized role in the regulation of drug metabolism and transport by xenobiotics, pregnane X receptor (PXR) critically ... Read more »
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Bioruptor Cell Lysis
A dynamic CTCF chromatin binding landscape promotes DNA hydroxymeth...
Published: September, 2014
Abstract: CCCTC-binding factor (CTCF) is a ubiquitously expressed multifunctional transcription factor characterized by chromatin binding patterns often desc... Read more »
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Bioruptor Cell Lysis
Mechanism-based genotoxicity screening of metal oxide nanoparticles...
Published: September, 2014
Abstract: BACKGROUND: The rapid expansion of manufacturing and use of nano-sized materials fuels the demand for fast and reliable assays to identify their po... Read more »
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Bioruptor

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