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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Published: July, 2014
Abstract: Mutations in the RNA-binding protein FUS have been shown to cause the neurodegenerative disease amyotrophic lateral sclerosis. We investigate wheth... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
bPeaks: a bioinformatics tool to detect transcription factor bindin...
Published: July, 2014
Abstract: Peak calling is a critical step in ChIPseq data analysis. Choosing the correct algorithm as well as optimized parameters for a specific biological ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Maintenance and replication of the human cytomegalovirus genome dur...
Published: July, 2014
Abstract: Human cytomegalovirus (HCMV) can establish latent infection in hematopoietic progenitor cells (HPCs) or CD14 (+) monocytes. While circularized vira... Read more »
Comparison of five different RNA sources to examine the lactating b...
Published: July, 2014
Abstract: The objective of this study was to examine five different sources of RNA, namely mammary gland tissue (MGT), milk somatic cells (SC), laser microdi... Read more »
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DNA shearing Bioruptor
Four methods of preparing mRNA 5' end libraries using the illumina ...
Published: July, 2014
Abstract: BACKGROUND: The 5' untranslated regions of mRNA play an important role in their translation. RESULTS: Here, we describe the development of four m... Read more »
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DNA shearing Bioruptor
Transcriptional regulation of LUX by CBF1 mediates cold input to th...
Published: July, 2014
Abstract: Circadian clocks allow organisms to anticipate daily changes in the environment to enhance overall fitness. Transcription factors (TFs) play a prom... Read more »
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Bioruptor Chromatin Shearing Bioruptor Plus
Epigenomic analysis of primary human T cells reveals enhancers asso...
Published: July, 2014
Abstract: A characteristic feature of asthma is the aberrant accumulation, differentiation or function of memory CD4(+) T cells that produce type 2 cytokines... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Histone Variant H2A.W Defines Heterochromatin and Promotes Chro...
Published: July, 2014
Abstract: Histone variants play crucial roles in gene expression, genome integrity, and chromosome segregation. We report that the four H2A variants in Arabi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Helicobacter pylori-induced STAT3 activation and signalling network...
Published: July, 2014
Abstract: Background: Helicobacter pylori (H. pylori) is the most important gastric carcinogen. However, the mechanisms of H. pylori induced gastric carcinog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ectopic DNMT3L triggers assembly of a repressive complex for retrov...
Published: July, 2014
Abstract: Mammalian genomes are replete with retrotransposable elements, including endogenous retroviruses. DNA methyltransferase 3-like (DNMT3L) is an epige... Read more »
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LowCell ChIP kit
Tissue specific insulator function at H19/Igf2 revealed by deletion...
Published: July, 2014
Abstract: Parent-of-origin specific expression at imprinted genes is regulated by allele-specific DNA methylation at imprinting control regions (ICRs). This ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gl...
Published: July, 2014
Abstract: Exposure to environmental estrogens (xenoestrogens) may play a causal role in the increased breast cancer incidence which has been observed in Euro... Read more »
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Antibody
Synergistic apoptosis in head and neck squamous cell carcinoma cell...
Published: July, 2014
Abstract: Background: In head and neck squamous cell carcinoma (HNSCC), resistance to single agent targeted therapy may be overcome by co-targeting of compen... Read more »
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Bioruptor Cell Lysis Western Blot
The interaction of MYC with the trithorax protein ASH2L promotes ge...
Published: July, 2014
Abstract: The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Identification of a large protein network involved in epigenetic tr...
Published: July, 2014
Abstract: Pluripotency of embryonic stem cells (ESCs) is maintained by transcriptional activities and chromatin modifying complexes highly organized within t... Read more »
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Bioruptor Chromatin Shearing Antibody H3K4me3 (C15410003)
The telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p ...
Published: July, 2014
Abstract: We provide evidence that a central player in ribosome synthesis, the ribonucleic acid helicase Prp43p, can be activated by yeast Gno1p and its huma... Read more »
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Bioruptor Cell Lysis
TET1 is a maintenance DNA demethylase that prevents methylation spr...
Published: July, 2014
Abstract: TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the preci... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Leishmania donovani chaperone cyclophilin 40 is essential for i...
Published: July, 2014
Abstract: During its life cycle, the protozoan pathogen Leishmania donovani is exposed to contrasting environments inside insect vector and vertebrate host, ... Read more »
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Bioruptor Cell Lysis
From transient transcriptome responses to disturbed neurodevelopmen...
Published: July, 2014
Abstract: The superordinate principles governing the transcriptome response of differentiating cells exposed to drugs are still unclear. Often, it is assumed... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Feasibility of a lateral flow test for neurocysticercosis using nov...
Published: July, 2014
Abstract: Neurocysticercosis is a frequent parasitic infection of the human brain, occurring in most of the world, and requires imaging of the brain to diagn... Read more »
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Bioruptor
Interactions with RNA direct the Polycomb group protein SCML2 to ch...
Published: July, 2014
Abstract: Polycomb repressive complex-1 (PRC1) is essential for the epigenetic regulation of gene expression. SCML2 is a mammalian homolog of Drosophila SCM,... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Functional Conservation of the Pre-Sensor One Beta-Finger Hairpin (...
Published: July, 2014
Abstract: Mini-chromosome maintenance (MCM) proteins form complexes that are required for DNA replication and are highly conserved throughout evolution. The ... Read more »
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Bioruptor Cell Lysis Western Blot
Genome-wide analysis of DNA 5-hmC in peripheral blood of uremia by ...
Published: July, 2014
Abstract: Abstract Background: Treatment of uremia is now dominated by dialysis; in some cases, patients are treated with dialysis for decades, but overall o... Read more »
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DNA shearing Bioruptor
Influence of ND10 Components on Epigenetic Determinants of Early KS...
Published: July, 2014
Abstract: We have previously demonstrated that acquisition of intricate patterns of activating (H3K4me3, H3K9/K14ac) and repressive (H3K27me3) histone modifi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Apigenin reactivates Nrf2 anti-oxidative stress signaling in mouse ...
Published: July, 2014
Abstract: Nrf2 is a crucial transcription factor that controls a critical anti-oxidative stress defense system and is implicated in skin homeostasis. Apigeni... Read more »
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MagMeDIP kit
GENOME-WIDE SCREEN OF PROMOTER METHYLATION IDENTIFIES NOVEL MARKERS...
Published: July, 2014
Abstract: OBJECTIVE: To investigate the genome-wide promoter methylation and gene expression for the identification of methylation markers in obesity. METHOD... Read more »
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DNA shearing Bioruptor Antibody
DNA topoisomerase 1α promotes transcriptional silencing of transpos...
Published: July, 2014
Abstract: RNA-directed DNA methylation (RdDM) and histone H3 lysine 9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target tr... Read more »
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DNA shearing Bioruptor
Divergent roles of histone deacetylase 6 (HDAC6) and histone deacet...
Published: July, 2014
Abstract: The anti-inflammatory cytokine IL-10 is a key modulator of immune responses. A better understanding of the regulation of this cytokine offers the p... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
3β,5α,6β-Cholestanetriol and 25-hydroxycholesterol accumulate in AT...
Published: July, 2014
Abstract: OBJECTIVE: Oxysterols are oxidized derivatives of sterols that have cytotoxic effects and are potent regulators of diverse cellular functions. Effi... Read more »
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Bioruptor Cell Lysis
Chromatin Profiling Reveals Regulatory Network Shifts and a Protect...
Published: June, 2014
Abstract: Transcriptional regulatory mechanisms likely contribute to the etiology of Inflammatory Bowel Disease (IBD), as genetic variants associated with th... Read more »
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Bioruptor Chromatin Shearing ChIP-seq

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