Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Mu-seq: Sequence-Based Mapping and Identification of Transposon Ind...
Published: October, 2013

Abstract: Mutations tagged by transposon insertions can be readily mapped and identified in organisms with sequenced genomes. Collections of such mutants all... Read more »

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DNA shearing Bioruptor
Identification of genes expressed by immune cells of the colon that...
Published: October, 2013

Abstract: A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this f... Read more »

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DNA shearing Bioruptor
A missense mutation accelerating the gating of the lysosomal Cl-/H+...
Published: October, 2013

Abstract: Chloride/proton exchange by the lysosomal anion transporter ClC-7/Ostm1 is of pivotal importance for the physiology of lysosomes and bone resorptio... Read more »

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DNA shearing Bioruptor
A molecular evolution approach to study the roles of tropomyosin in...
Published: October, 2013

Abstract: Tropomyosin, a coiled-coil protein that binds along the length of the actin filament, is a universal regulator of the actin cytoskeleton. We have t... Read more »

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Bioruptor
The double PHD finger domain of MOZ/MYST3 induces α-helical structu...
Published: October, 2013

Abstract: Histone tail modifications control many nuclear processes by dictating the dynamic exchange of regulatory proteins on chromatin. Here we report nov... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
A functionally conserved Polycomb response element from mouse HoxD ...
Published: October, 2013

Abstract: Anterior-posterior body axis in all bilaterians is determined by the Hox gene clusters that are activated in a spatio-temporal order. This expressi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Early adipogenesis is regulated through USP7-mediated deubiquitinat...
Published: October, 2013

Abstract: Transcriptional coregulators, including the acetyltransferase Tip60, have a key role in complex cellular processes such as differentiation. Whereas... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The Elongin Complex Antagonizes the Chromatin Factor Corto for Vein...
Published: October, 2013

Abstract: Drosophila wings mainly consist of two cell types, vein and intervein cells. Acquisition of either fate depends on specific expression of genes tha... Read more »

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Antibody IPure kit
Genome-wide and cell-specific epigenetic analysis challenges the ro...
Published: October, 2013

Abstract: The Drosophila spermatogenesis cell differentiation pathway involves the activation of a large set of genes in primary spermatocytes. Most of these... Read more »

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Bioruptor Chromatin Shearing
Targeted disruption of hotair leads to homeotic transformation and ...
Published: October, 2013

Abstract: Long noncoding RNAs (lncRNAs) are thought to be prevalent regulators of gene expression, but the consequences of lncRNA inactivation in vivo are mo... Read more »

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Antibody H3K27me3 (C15410069)
IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression du...
Published: October, 2013

Abstract: BACKGROUND: Whereas recent research has characterized the mechanism by which dendritic cells (DCs) induce TH1/TH17 responses, the functional specia... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Gene dysregulation by histone variant H2A.Z in bladder cancer
Published: October, 2013

Abstract: Background The incorporation of histone variants into nucleosomes is one of the main strategies that the cell uses to regulate the structure and ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
The SERRATE protein is involved in alternative splicing in Arabidop...
Published: October, 2013

Abstract: How alternative splicing (AS) is regulated in plants has not yet been elucidated. Previously, we have shown that the nuclear cap-binding protein co... Read more »

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Bioruptor Cell Lysis Bioruptor Plus
Gene regulatory scenarios of primary 1,25-dihydroxyvitamin d3 targe...
Published: October, 2013

Abstract: Genome- and transcriptome-wide data has significantly increased the amount of available information about primary 1,25-dihydroxyvitamin D3 (1,25(OH... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Dimethyl fumarate regulates histone deacetylase expression in astro...
Published: October, 2013

Abstract: We previously showed that dimethyl fumarate (DMF) reduces inflammatory activation in astrocytes, involving activation of transcription factor Nrf2.... Read more »

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Antibody
Evidence of population bottleneck in Astragalus michauxii (Fabaceae...
Published: October, 2013

Abstract: Genetic factors such as decreased genetic diversity and increased homozygosity can have detrimental effects on rare species, and may ultimately lim... Read more »

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DNA shearing Bioruptor
Blimp1 (Prdm1) prevents re-specification of photoreceptors into ret...
Published: October, 2013

Abstract: During retinal development, photoreceptors and bipolar cells express the transcription factor Otx2. Blimp1 is transiently expressed in Otx2+ cells.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Lack of decorin expression by human bladder cancer cells offers new...
Published: October, 2013

Abstract: Decorin, a multifunctional small leucine-rich extracellular matrix proteoglycan, has been shown to possess potent antitumour activity. However, the... Read more »

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IP-Star
CTCF binding site sequence differences are associated with unique r...
Published: October, 2013

Abstract: CTCF (CCCTC-binding factor) is a highly conserved multifunctional DNA-binding protein with thousands of binding sites genome-wide. Our previous wor... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Global analysis of eukaryotic mRNA degradation reveals Xrn1-depende...
Published: October, 2013

Abstract: The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be monitored by comparative dynamic transcriptome analysis (cDTA... Read more »

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Bioruptor
Global DNA methylation screening of liver in piperonyl butoxide-tre...
Published: October, 2013

Abstract: Disruptive epigenetic gene control has been shown to be involved in carcinogenesis. To identify key molecules in piperonyl butoxide (PBO)-induced h... Read more »

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DNA shearing Antibody MeDIP kit 5mC (C15200081)
NLRP7 affects trophoblast lineage differentiation, binds to overexp...
Published: October, 2013

Abstract: Maternal-effect mutations in NLRP7 cause rare biparentally inherited hydatidiform moles (BiHMs), abnormal pregnancies containing hypertrophic vesic... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryon...
Published: October, 2013

Abstract: The self-renewal and pluripotency of embryonic stem cells (ESC) is regulated by a highly integrated network of essential transcription factors, whi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Combined modulation of polycomb and trithorax genes rejuvenates β c...
Published: October, 2013

Abstract: Inadequate functional β cell mass underlies both type 1 and type 2 diabetes. β Cell growth and regeneration also decrease with age through mechanis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Spt6 regulates intragenic and antisense transcription, nucleosome p...
Published: October, 2013

Abstract: Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Membrane-to-nucleus signaling links insulin-like growth factor-1- a...
Published: October, 2013

Abstract: STEM CELL FACTOR (MOUSE: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
A Conserved Protein Motif Is Required for Full Modulatory Activity ...
Published: October, 2013

Abstract: NELF-B is a BRCA1-interacting protein and subunit (with NELF-A, -C/D, and -E) of the human negative elongation factor (NELF) complex, which partici... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Angiomodulin is required for cardiogenesis of embryonic stem cells ...
Published: October, 2013

Abstract: The transcription factor p63, member of the p53 gene family, encodes for two main isoforms, TAp63 and ΔNp63 with distinct functions on epithelial h... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Class I Lysine Deacetylases Facilitate Glucocorticoid-induced Trans...
Published: October, 2013

Abstract: Nuclear receptors use lysine acetyltransferases and lysine deacetylases (KDACs) in regulating transcription through histone acetylation. Lysine ace... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (...
Published: October, 2013

Abstract: Here we sought to identify transcription factors that induce ADAMTS5, a crucial proteinase for osteoarthritis development. Exhaustive comparison of... Read more »

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